On Methods of Checking Digital Out-Of-Step Protection Devices

The article addressed the issue of commissioning task that must take place before putting out-ofstep protection into operation. Most of the developers of digital out-of-step protection devices utilize control of impedance vector locus parameter during transient in a power system to detect its out-of-step operation, however checking the setting of such protection in the field conditions using existing means is often a challenging work. To facilitate the commissioning of such devices and provide means to automatize the process so as to rid of human factor the authors suggest means of simulating impedance vector locus with the desired parameters on the complex plane to check distance out-of-step protection. The means for checking current-oscillation based out-of-step protection is also considered. The results of a transient simulation representing instantaneous values of currents and voltages are saved in the international oscillography recording format COMTRADE, which makes it possible to carry out comprehensive verification of emergency control equipment using any kind of testing equipment that is able to generate the corresponding electrical signals stored in such format

Genome-Wide Study of Drug Resistant Mycobacterium tuberculosis and Its Intra-Host Evolution during Treatment

The emergence of drug resistant Mycobacterium tuberculosis (MTB) strains has become a global public health problem, while, at the same time, there has been development of new antimicrobial agents. The main goals of this study were to determine new variants associated with drug resistance in MTB and to observe which polymorphisms emerge in MTB genomes after anti-tuberculosis treatment. We performed whole-genome sequencing of 152 MTB isolates including 70 isolates as 32 series of pre- and post-treatment MTB. Based on genotypes and phenotypic drug susceptibility, we conducted phylogenetic convergence-based genome-wide association study (GWAS) with streptomycin-, isoniazid-, rifampicin-, ethambutol-, fluoroquinolones-, and aminoglycosides-resistant MTB against susceptible ones. GWAS revealed statistically significant associations of SNPs within Rv2820c, cyp123 and indels in Rv1269c, Rv1907c, Rv1883c, Rv2407, Rv3785 genes with resistant MTB phenotypes. Comparisons of serial isolates showed that treatment induced different patterns of intra-host evolution. We found indels within Rv1435c and ppsA that were not lineage-specific. In addition, Beijing-specific polymorphisms within Rv0036c, Rv0678, Rv3433c, and dop genes were detected in post-treatment isolates. The appearance of Rv3785 frameshift insertion in 2 post-treatment strains compared to pre-treatment was also observed. We propose that the insertion within Rv3785, which was a GWAS hit, might affect cell wall biosynthesis and probably mediates a compensatory mechanism in response to treatment. These results may shed light on the mechanisms of MTB adaptation to chemotherapy and drug resistance formation

Poor but not by choice(s): The persistence of cognitive biases across economic groups

While economic inequality continues to rise within countries, efforts to address it have been largely ineffective, particularly those involving behavioral approaches. It is often implied but not tested that patterns among low-income individuals may be a factor impeding behavioral interventions aimed at improving upward economic mobility. To test this, we assessed rates of ten cognitive biases across nearly 5,000 participants from 27 countries, comparing between low-income adults and individuals that had overcome financial disadvantages as children, known as positive deviants. Using discrete and complex models, we find robust evidence of no differences within or between groups or countries. We therefore conclude without reservation that choices impeded by cognitive biases alone cannot explain why some individuals do not experience upward economic mobility. Policies must combine both behavioral and structural interventions to improve financial well-being across populations

The persistence of cognitive biases in financial decisions across economic groups

Abstract While economic inequality continues to rise within countries, efforts to address it have been largely ineffective, particularly those involving behavioral approaches. It is often implied but not tested that choice patterns among low-income individuals may be a factor impeding behavioral interventions aimed at improving upward economic mobility. To test this, we assessed rates of ten cognitive biases across nearly 5000 participants from 27 countries. Our analyses were primarily focused on 1458 individuals that were either low-income adults or individuals who grew up in disadvantaged households but had above-average financial well-being as adults, known as positive deviants. Using discrete and complex models, we find evidence of no differences within or between groups or countries. We therefore conclude that choices impeded by cognitive biases alone cannot explain why some individuals do not experience upward economic mobility. Policies must combine both behavioral and structural interventions to improve financial well-being across populations

The persistence of cognitive biases in financial decisions across economic groups.

Acknowledgements: We thank the Junior Researcher Programme, Global Behavioral Science (GLOBES), Department of Psychology, Columbia University; the Centre for Business Research, Judge Business School, University of Cambridge; Corpus Christi College, Cambridge; and Dr Ceren Sönmez, Michal Goldstein, Abby Yucht, and Anastasia Gracheva. This research was supported in part by the National Science Foundation (#2218595) and by Undergraduate Global Engagement at Columbia University. Additional support was provided to individual researchers from the Columbia University Office of the Provost, Masaryk University Centre for International Cooperation, and the Benjamin A. Gilman International Fund from the United States Department of State. This research was funded in part, by the UKRI [MR/N013468/1]. For the purpose of Open Access, the author has applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission.While economic inequality continues to rise within countries, efforts to address it have been largely ineffective, particularly those involving behavioral approaches. It is often implied but not tested that choice patterns among low-income individuals may be a factor impeding behavioral interventions aimed at improving upward economic mobility. To test this, we assessed rates of ten cognitive biases across nearly 5000 participants from 27 countries. Our analyses were primarily focused on 1458 individuals that were either low-income adults or individuals who grew up in disadvantaged households but had above-average financial well-being as adults, known as positive deviants. Using discrete and complex models, we find evidence of no differences within or between groups or countries. We therefore conclude that choices impeded by cognitive biases alone cannot explain why some individuals do not experience upward economic mobility. Policies must combine both behavioral and structural interventions to improve financial well-being across populations