8,795 research outputs found
The organization and management of the Virtual Astronomical Observatory
The U.S. Virtual Astronomical Observatory (VAO; http://www.us-vao.org/) has
been in operation since May 2010. Its goal is to enable new science through
efficient integration of distributed multi-wavelength data. This paper
describes the management and organization of the VAO, and emphasizes the
techniques used to ensure efficiency in a distributed organization. Management
methods include using an annual program plan as the basis for establishing
contracts with member organizations, regular communication, and monitoring of
processes.Comment: 9 pages, 3 figures. SPIE Conference 8449: Modeling, Systems
Engineering, and Project Management for Astronomy
Quantifying Compliance Costs for Small Businesses in New Zealand
This paper reports on a small-scale study of the compliance costs of small New Zealand businesses. Participating firms were asked to keep a record of both time spent and expenditure directly incurred over a thirteen-week period. This differs from previous studies that rely on a firm's recall of how much time has been spent on compliance over the previous year. The results suggest that New Zealand small businesses on average spend less time and money on compliance than has been indicated in previous studies. However a number offirms do perceive compliance to be a major issue and in some cases this perception prevents firms from expanding
Bostonia. Volume 13
Founded in 1900, Bostonia magazine is Boston University's main alumni publication, which covers alumni and student life, as well as university activities, events, and programs
Polarization of macrophages toward M2 phenotype is favored by reduction in iPLA2β (group VIA phospholipase A2)*
Macrophages are important in innate and adaptive immunity. Macrophage participation in inflammation or tissue repair is directed by various extracellular signals and mediated by multiple intracellular pathways. Activation of group VIA phospholipase A2 (iPLA2β) causes accumulation of arachidonic acid, lysophospholipids, and eicosanoids that can promote inflammation and pathologic states. We examined the role of iPLA2β in peritoneal macrophage immune function by comparing wild type (WT) and iPLA2β−/− mouse macrophages. Compared with WT, iPLA2β−/− macrophages exhibited reduced proinflammatory M1 markers when classically activated. In contrast, anti-inflammatory M2 markers were elevated under naïve conditions and induced to higher levels by alternative activation in iPLA2β−/− macrophages compared with WT. Induction of eicosanoid (12-lipoxygenase (12-LO) and cyclooxygenase 2 (COX2))- and reactive oxygen species (NADPH oxidase 4 (NOX4))-generating enzymes by classical activation pathways was also blunted in iPLA2β−/− macrophages compared with WT. The effects of inhibitors of iPLA2β, COX2, or 12-LO to reduce M1 polarization were greater than those to enhance M2 polarization. Certain lipids (lysophosphatidylcholine, lysophosphatidic acid, and prostaglandin E2) recapitulated M1 phenotype in iPLA2β−/− macrophages, but none tested promoted M2 phenotype. These findings suggest that (a) lipids generated by iPLA2β and subsequently oxidized by cyclooxygenase and 12-LO favor macrophage inflammatory M1 polarization, and (b) the absence of iPLA2β promotes macrophage M2 polarization. Reducing macrophage iPLA2β activity and thereby attenuating macrophage M1 polarization might cause a shift from an inflammatory to a recovery/repair milieu
Statistical Computations with AstroGrid and the Grid
We outline our first steps towards marrying two new and emerging
technologies; the Virtual Observatory (e.g, AstroGrid) and the computational
grid. We discuss the construction of VOTechBroker, which is a modular software
tool designed to abstract the tasks of submission and management of a large
number of computational jobs to a distributed computer system. The broker will
also interact with the AstroGrid workflow and MySpace environments. We present
our planned usage of the VOTechBroker in computing a huge number of n-point
correlation functions from the SDSS, as well as fitting over a million CMBfast
models to the WMAP data.Comment: Invited talk to appear in "Proceedings of PHYSTAT05: Statistical
Problems in Particle Physics, Astrophysics and Cosmology
Saturation Effects in a Tunable Coherent Near-Infrared Source
A Saturation Effect in a Tunable Infrared Source Utilizing Four-Wave Parametric Conversion in Potassium Vapor is Reported and is Shown to Be the Result of Parasitic Oscillations. a Hundredfold Increase over Previously Attained Power Levels Has Been Affected Via Elimination of These Oscillations
The Statistical Approach to Quantifying Galaxy Evolution
Studies of the distribution and evolution of galaxies are of fundamental
importance to modern cosmology; these studies, however, are hampered by the
complexity of the competing effects of spectral and density evolution.
Constructing a spectroscopic sample that is able to unambiguously disentangle
these processes is currently excessively prohibitive due to the observational
requirements. This paper extends and applies an alternative approach that
relies on statistical estimates for both distance (z) and spectral type to a
deep multi-band dataset that was obtained for this exact purpose.
These statistical estimates are extracted directly from the photometric data
by capitalizing on the inherent relationships between flux, redshift, and
spectral type. These relationships are encapsulated in the empirical
photometric redshift relation which we extend to z ~ 1.2, with an intrinsic
dispersion of dz = 0.06. We also develop realistic estimates for the
photometric redshift error for individual objects, and introduce the
utilization of the galaxy ensemble as a tool for quantifying both a
cosmological parameter and its measured error. We present deep, multi-band,
optical number counts as a demonstration of the integrity of our sample. Using
the photometric redshift and the corresponding redshift error, we can divide
our data into different redshift intervals and spectral types. As an example
application, we present the number redshift distribution as a function of
spectral type.Comment: 40 pages (LaTex), 21 Figures, requires aasms4.sty; Accepted by the
Astrophysical Journa
Efficient Photometric Selection of Quasars from the Sloan Digital Sky Survey: 100,000 z<3 Quasars from Data Release One
We present a catalog of 100,563 unresolved, UV-excess (UVX) quasar candidates
to g=21 from 2099 deg^2 of the Sloan Digital Sky Survey (SDSS) Data Release One
(DR1) imaging data. Existing spectra of 22,737 sources reveals that 22,191
(97.6%) are quasars; accounting for the magnitude dependence of this
efficiency, we estimate that 95,502 (95.0%) of the objects in the catalog are
quasars. Such a high efficiency is unprecedented in broad-band surveys of
quasars. This ``proof-of-concept'' sample is designed to be maximally
efficient, but still has 94.7% completeness to unresolved, g<~19.5, UVX quasars
from the DR1 quasar catalog. This efficient and complete selection is the
result of our application of a probability density type analysis to training
sets that describe the 4-D color distribution of stars and spectroscopically
confirmed quasars in the SDSS. Specifically, we use a non-parametric Bayesian
classification, based on kernel density estimation, to parameterize the color
distribution of astronomical sources -- allowing for fast and robust
classification. We further supplement the catalog by providing photometric
redshifts and matches to FIRST/VLA, ROSAT, and USNO-B sources. Future work
needed to extend the this selection algorithm to larger redshifts, fainter
magnitudes, and resolved sources is discussed. Finally, we examine some science
applications of the catalog, particularly a tentative quasar number counts
distribution covering the largest range in magnitude (14.2<g<21.0) ever made
within the framework of a single quasar survey.Comment: 35 pages, 11 figures (3 color), 2 tables, accepted by ApJS; higher
resolution paper and ASCII version of catalog available at
http://sdss.ncsa.uiuc.edu/qso/nbckde
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