Opinions about Perceived Linguistic Intelligibility in Late-Medieval Italy

This article contributes to the historical study of intercomprehension between speakers of closely related languages by focusing on Italy in the period up to the mid-fifteenth century. After an introduction to the topic, the second section will be devoted to methodological questions, including certain differences between research based on experimental testing and research based on historical evidence. The third section of the article reports opinions by medieval speakers about the intelligibility of different Italo-Romance varieties, and then compares them to opinions about genealogically and/or geographically more distant languages. While the dominant view among experts on Italy’s linguistic history is that speakers were trapped within mutually unintelligible vernaculars, this review of the extant evidence suggests a greater degree of intercomprehension than is usually supposed.acceptedVersio

Cultural tourism development and the impact on local communities: a case study from the South of Italy

Cultural tourism is the idea that a place’s cultural perception has enough value to make it a destination for travel. Communities characterized by a high level of cultural development are usually associated with a high level of satisfaction about living conditions and wealth. In this research, we postulate that the creation and development of the cultural attractions of a place to attract tourists also have a positive impact on the life condition of the local community, not only for increased money availability but also for a change of inhabitants’ mind-set. Case study methodology has been used to support the hypotheses

Right ventricular restoration during pulmonary valve implantation in adults with congenital heart disease☆

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Understanding demand for innovation in the food industry

Purpose – This paper aims to focus on understanding how demand for innovation is articulated in low-tech industries, dominated by SMEs, where innovation is often based on informal processes and uncodified knowledge, relying on intangible assets. Design/methodology/approach – The authors hypothesize that the problems found in the innovation area are exacerbated in a traditional industry. SMEs might have difficulty understanding what their requirements might be, let alone finding the optimal provider of technologies. The authors therefore expect to find three main forms of demand: real, latent, and potential. The specific case is the food industry in Apulia, Italy. First, focus groups identified general business and technology needs. Then in-depth interviews were conducted with 87 firms, stratified in order to be representative of food firms in Apulia. Findings – The authors detected 285 different needs requiring an innovative solution. In most cases, firms understand the areas to be improved, but do not have a technological solution in mind. Demand for innovation is mostly latent. Research limitations/implications – The study is narrow in geographic and industry scope. This limits generalizability, but the methodology is transferable and the results comparable. The authors studied the demand side, whereas interaction between supply and demand needs to be understood. Future studies into regional public research organizations (PROs) and intermediaries can therefore be useful. Practical implications – The findings can be used to understand how PROs can engage with SMEs and what policymakers can do to facilitate the interaction. Originality/value – This study applies thinking typically used in high-tech sectors to a traditional sector, hence testing and extending the theoretical boundaries.Alessandro Muscio, Gianluca Nardone and Antonio Dottor

Ct-Guided Pancreatic Percutaneous Fine-needle Biopsy in Differential Diagnosis Between Pancreatic Cancer and Chronic Pancreatitis

Differential diagnosis between pancreatic cancer and chronic pancreatitis is still difficult to establish. In 63 patients with suspected pancreatic neoplasm we performed: serum CA 19-9 assessment, abdominal ultrasound, CT scan and CT-guided pancreatic percutaneous fine-needle biopsy. The conclusive diagnosis was pancreatic cancer in 40 patients and chronic pancreatitis in 23 patients. With regard to the differential diagnosis, sensitivity and specificity were respectively 80% and 78% for serum CA 19-9, 75% and 65% for abdominal US, 85% and 70% for CT scan, 00% and 87% for percutaneous fine-needle biopsy. We conclude that CT-guided percutaneous fine-needle biopsy is the most reliable method for differential diagnosis between pancreatic cancer and chronic pancreatitis

Placental Chorangiocarcinoma a Specific Histological Pattern of Uncertain Incidence and Clinical Impact: Systematic Review of the Literature

Chorangiocarcinoma is a very rare and misdiagnosed placental neoplasm. The unique morphologic features of the lesion distinguish it from other trophoblastic tumors and vascular abnormalities. We present a systematic review of the literature to provide clarity on chorangiocarcinoma entity and biology. A literature search was carried out in December 2022 using the keywords "Placental chorangiocarcinoma", "Chorangioma", "Placenta", and "Throphoblast proliferation". Articles published from 1988 to 2022 were obtained from Scopus, Google Scholar, and PUBMED. In our review, we examined maternal age, gestational age at the time of delivery, parity, type of pregnancy, placental weight, ultrasound features of the placenta, macroscopic examination and tumor size, microscopic examination, immunostaining, maternal beta-human chorionic gonadotropin, fetal and maternal outcome. Eight manuscripts were detected. They are all case reports. The macroscopic characteristics of the lesions were represented by the presence of a grey-yellow-white color well-demarcated round nodule. Microscopically, all the authors described typical aspects of malignancy as a high rate of mitosis, nuclear atypia and necrotic areas. In some cases, the presence of AE1/AE3 cytoplasmic positivity, p63 nuclear staining, and beta-human chorionic gonadotropin (BHCG) were reported. A good fetal outcome was reported in all cases of newborns with normal birth weight, except one with fetal growth restriction. Maternal outcome was good in all cases except one with maternal lung metastasis three months after delivery. The clinical course has probably underestimated the real incidence of the pathology. Only greater knowledge of its histology and its clinical course will allow us to evaluate the real prevalence of the disease

Numerical and experimental analysis of the leaning Tower of Pisa under earthquake

Twenty years have passed from the most recent studies about the dynamic behavior of the leaning Tower of Pisa. Significant changes have occurred in the meantime, the most important ones concerning the soil-structure interaction. From 1999 to 2001, the foundation of the monument was consolidated through under-excavation, and the "Catino" at the basement was rigidly connected to the foundation. Moreover, in light of the recent advances in the field of earthquake engineering, past studies about the Tower must be revised. Therefore, the present research aims at providing new data and results about the structural response of the Tower under earthquake. As regards the experimental assessment of the Tower, the dynamic response of the structure recorded during some earthquakes has been analyzed in the time- and frequency-domain. An Array 2D test has been performed in the Square of Miracles to identify a soil profile suitable for site response analyses, thus allowing the definition of the free-field seismic inputs at the base of the Tower. On the other hand, a synthetic evaluation of the seismic input in terms of response spectra has been done by means of a hybrid approach that combines Probabilistic and Deterministic Seismic Hazard Assessment methods. Furthermore, natural accelerograms have been selected and scaled properly. A finite element model that takes into account the inclination of the structure has been elaborated, and it has been updated taking into account the available experimental results. Finally, current numerical and experimental efforts for enhancing the seismic characterization of the Tower have been illustrated

Toward the circular economy into the olive oil supply chain: A case study analysis of a vertically integrated firm

While the paradigm of circular economy (CE) and the processes of socio-technical transition have been broadly investigated at the theoretical level, understanding how the transition toward circular models can be implemented in practice is still limited. This contribution aims to provide in-depth and evidence-based insights on an emerging pathway for the operability of CE into the olive oil supply chain. A case study from the Apulia region (the leading olive oil producing area in Italy) is presented to show how an existing business model can be transformed into a circular one, and to what extent it can be replicated. The study focuses on a vertically integrated firm, in which a new industrial process has been introduced to manage olive pomace, which is one of the most important by-products obtained from olive oil extraction. The empirical analysis is built on the Circular Business Model Canvas (CBMC), which is conceived as a suitable theoretical and methodological tool to speed up the transition process toward CE at a micro-economic level. This analytical framework allows us to identify the interplaying elements that the firm combines to capture, create, and deliver value, as well as the relationships with the broader economic system. Particular attention is paid to two distinctive components of CBMC: material loops and adoption factors. Also, internal and external factors affecting the adoption of the new circular business model have been discussed by separating drivers and barriers of the transition process