138 research outputs found
La clase invertida: el papel de las actividades previas en el rendimiento final del alumno
[ES] El modelo de la clase invertida o flipped classroom consiste en dar la vuelta a la organización del modelo tradicional docente, sacando la transmisión de conocimientos fuera del aula y dejar tiempo de aula para propiciar un aprendizaje más activo y profundo en el alumnado. En la presente innovación se estudió el impacto que tiene visualizar vídeos con preguntas incrustadas sobre el rendimiento final en la asignatura. Los resultados mostraron por un lado que existe una relación marginalmente significativa entre la visualización de vídeos y el rendimiento en la prueba final de la asignatura. Por otro, se halló una correlación positiva aunque moderada entre las puntuaciones obtenidas en las preguntas incrustadas en los vídeos y la puntuación en el examen final. Estos resultados concuerdan con la idea de que es posible lograr un procesamiento más profundo de la información y, por tanto, un mejor recuerdo de la misma, cuando se insertan preguntas a lo largo de los vídeos[EN] The flipped classroom model consists on a re-arrangement of the traditional instructional model, in the sense that the lectures are placed out of the classroom whereas the classroom time is devoted to promote a more active and deeper learning in the students. This innovation was aimed to study the impact of viewing videos with questions embeded along it on the final achievent of the students. Results showed that there is a marginal relationship between watching videos and the score on the final test of the course. In addition, a possitive correlation between the scores obtained on the questions of the videos and the score on the final test was obtained. This results are in accordance with the idea that embeding questions along the videos leads to a more profound proccessing of the information, and therefore, a better learning.López-Crespo, G.; Fidalgo, C.; Martín-Albo, J.; Valdivia-Salas, S.; Lerma-Cabrera, JM.; Carvajal-Ruiz, M.; Carralero-Esteban, D. (2021). La clase invertida: el papel de las actividades previas en el rendimiento final del alumno. En IN-RED 2020: VI Congreso de Innovación Educativa y Docencia en Red. Editorial Universitat Politècnica de València. 104-109. https://doi.org/10.4995/INRED2020.2020.11994OCS10410
Autologous stem cell transplantation may be curative for patients with follicular lymphoma with early therapy failure without the need for immunotherapy
Objective/Background: Patients with follicular lymphoma (FL) with early therapy failure (ETF) within 2 years of frontline therapy have poor overall survival (OS). We recently reported the results of autologous stem cell transplantation (ASCT) in patients from the Grupo Español de Linfomas y Trasplantes de Médula Ósea (GELTAMO) registry treated with rituximab prior to ASCT and with ETF after first-line immunochemotherapy, leading to 81% 5-year OS since ASCT. We explored whether ASCT is also an effective option in the pre-rituximab era—that is, in patients treated in induction and rescued only with chemotherapy.
Methods: ETF was defined as relapse/progression within 2 years of starting first-line therapy. We identified two groups: the ETF cohort (n = 87) and the non-ETF cohort (n = 47 patients receiving ASCT but not experiencing ETF following first-line therapy).
Results: There was a significant difference in 5-year progression-free survival between the ETF and non-ETF cohorts (43% vs. 57%, respectively; p = .048). Nevertheless, in patients with ETF with an interval from first relapse after primary treatment to ASCT of <1 year, no differences were observed in 5-year progression-free survival (48% vs. 66%, respectively; p = .44) or in 5-year OS (69% vs. 77%, p = .4). Patients in the ETF cohort transplanted in complete remission showed a plateau in the OS curves, at 56%, beyond 13.7 years of follow-up.
Conclusion: ASCT may be a curative option for ETF in patients who respond to rescue chemotherapy, without the need for immunotherapy or other therapies, and should be considered as an early consolidation, especially in patients with difficult access to rituximab
Radon and material radiopurity assessment for the NEXT double beta decay experiment
The Neutrino Experiment with a Xenon TPC (NEXT), intended to investigate the
neutrinoless double beta decay using a high-pressure xenon gas TPC filled with
Xe enriched in 136Xe at the Canfranc Underground Laboratory in Spain, requires
ultra-low background conditions demanding an exhaustive control of material
radiopurity and environmental radon levels. An extensive material screening
process is underway for several years based mainly on gamma-ray spectroscopy
using ultra-low background germanium detectors in Canfranc but also on mass
spectrometry techniques like GDMS and ICPMS. Components from shielding,
pressure vessel, electroluminescence and high voltage elements and energy and
tracking readout planes have been analyzed, helping in the final design of the
experiment and in the construction of the background model. The latest
measurements carried out will be presented and the implication on NEXT of their
results will be discussed. The commissioning of the NEW detector, as a first
step towards NEXT, has started in Canfranc; in-situ measurements of airborne
radon levels were taken there to optimize the system for radon mitigation and
will be shown too.Comment: Proceedings of the Low Radioactivity Techniques 2015 workshop
(LRT2015), Seattle, March 201
Measurement of radon-induced backgrounds in the NEXT double beta decay experiment
The measurement of the internal Rn activity in the NEXT-White
detector during the so-called Run-II period with Xe-depleted xenon is
discussed in detail, together with its implications for double beta decay
searches in NEXT. The activity is measured through the alpha production rate
induced in the fiducial volume by Rn and its alpha-emitting progeny.
The specific activity is measured to be ~mBq/m. Radon-induced electrons have also been
characterized from the decay of the Bi daughter ions plating out on the
cathode of the time projection chamber. From our studies, we conclude that
radon-induced backgrounds are sufficiently low to enable a successful NEXT-100
physics program, as the projected rate contribution should not exceed
0.1~counts/yr in the neutrinoless double beta decay sample.Comment: 28 pages, 10 figures, 6 tables. Version accepted for publication in
JHE
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Demonstration of the event identification capabilities of the NEXT-White detector
In experiments searching for neutrinoless double-beta decay, the possibility of identifying the two emitted electrons is a powerful tool in rejecting background events and therefore improving the overall sensitivity of the experiment. In this paper we present the first measurement of the efficiency of a cut based on the different event signatures of double and single electron tracks, using the data of the NEXT-White detector, the first detector of the NEXT experiment operating underground. Using a 228Th calibration source to produce signal-like and background-like events with energies near 1.6 MeV, a signal efficiency of 71.6 ± 1.5 stat± 0.3 sys% for a background acceptance of 20.6 ± 0.4 stat± 0.3 sys% is found, in good agreement with Monte Carlo simulations. An extrapolation to the energy region of the neutrinoless double beta decay by means of Monte Carlo simulations is also carried out, and the results obtained show an improvement in background rejection over those obtained at lower energies. [Figure not available: see fulltext.
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Energy calibration of the NEXT-White detector with 1% resolution near Q ββ of 136Xe
Excellent energy resolution is one of the primary advantages of electroluminescent high-pressure xenon TPCs. These detectors are promising tools in searching for rare physics events, such as neutrinoless double-beta decay (ββ0ν), which require precise energy measurements. Using the NEXT-White detector, developed by the NEXT (Neutrino Experiment with a Xenon TPC) collaboration, we show for the first time that an energy resolution of 1% FWHM can be achieved at 2.6 MeV, establishing the present technology as the one with the best energy resolution of all xenon detectors for ββ0ν searches. [Figure not available: see fulltext.
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