1,262 research outputs found
The White Marble of the Arch of Augustus (Susa, North-Western Italy): Mineralogical and Petrographic Analysis for the Definition of its Origin
Design Of Two-Stage On/Off Cartridge Valves For Mobile Applications
Cartridge valves are widely used in mobile applications, where they are screwed in manifolds, to realize opportune circuit layouts. These valves are quite simple in operation but require a sophisticated design in order to meet all the requirements needed in the mobile machines. Typically, the design process is developed realizing a first design concept and some prototypes and experimentally testing them; after this, the designer chases the optimal performances requested to the valve with a trial and error approach on the prototypes, involving high time and cost resources. In this paper an alternative design procedure is proposed, which involves dedicated simulations to analyze the main critical issues regarding the cartridge valve object of the study. Modelling and simulations here have been considered as steps into the design process of a new valve, which satisfies the requirements and well adapt to the necessities to operate at higher flow and pressure levels without compromising its performances. In that way, the number of prototypes, realized to validate the numerical results and verify the design process, has been considerably reduced, together with related time and costs
Pressure losses in hydraulic manifolds
Hydraulic manifolds are used to realize compact circuit layout, but may introduce a high pressure drop in the system. Their design is in fact oriented more toward achieving minimum size and weight than to reducing pressure losses. This work studies the pressure losses in hydraulic manifolds using different methods: Computational Fluid Dynamic (CFD) analysis; semi-empirical formulation derived from the scientific literature, when available; and experimental characterization. The purpose is to obtain the pressure losses when the channels' connections within the manifold are not ascribable to the few classic cases studied in the literature, in particular for 90° bends (elbows) with expansion/contraction and offset intersection of channels. Moreover, since CFD analysis is used to predict pressure losses, general considerations of the manifold design may be outlined and this will help the design process in the optimization of flow passages. The main results obtained show how CFD analysis overestimates the experimental results; nevertheless, the numerical analysis represents the correct trends of the pressure losses
Design and experimental development of a compact and efficient range extender engine
The paper reviews the design and experimental development of an original range-extender single-cylinder two-stroke gasoline engine, rated at 30 kW (maximum engine speed: 4500 rpm). The goal of the project is to get most of the benefits of the two-stroke cycle (compactness, high power density, low cost), while addressing the typical issues affecting the conventional engines of this type. Among many recent similar propositions, the peculiarities of this engine, besides the cycle, are: external scavenging by means of an electric supercharger, piston controlled scavenge and exhaust ports (no poppet valves), gasoline direct injection (GDI), and a patented rotary valve for the optimization of the scavenging process, of the loop type. Lubrication is identical to a conventional four-stroke engine, and the rotary valve, connected to the crankshaft, helps to improve the balance of the piston reciprocating forces, yielding an excellent NVH behavior. It should be noted that, except the patented rotary valve, all the engine parts are standard automotive commercial components, that don’t require any specific expensive technology. In fact, the originality of the engine consists in the optimum combination of existing well assessed concepts.
The scavenging and combustion systems of the engine are developed in the first phase of the project, including the construction and the experimental testing of a prototype. In the second phase, the air metering system of the prototype is completely modified: the piston pump is replaced by an electric supercharger, and engine load is now controlled by the supercharger speed, without throttle valve.
The new engine is compared to a standard 4-stroke engine, developed in a previous project for the same application. The main advantages of the two-stroke engine may be summarized as follows: lower weight (−35%), higher brake efficiency (+6%, on average), less heat rejected (−18%), lower thermal and mechanical loads within the cylinder (−40%). The only concern, that will be addressed in a future phase of the study, is the compliance with very low NOx limits: in the worst scenario, the 2-stroke engine could be forced to adopt a well assessed but expensive after-treatment device
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial
Objectives To determine the efficacy of intraoperative treatment with low dose tranexamic acid in reducing the rate of perioperative transfusions in patients undergoing radical retropubic prostatectomy
Robot Pose Nowcasting: Forecast the Future to Improve the Present
In recent years, the effective and safe collaboration between humans and
machines has gained significant importance, particularly in the Industry 4.0
scenario. A critical prerequisite for realizing this collaborative paradigm is
precisely understanding the robot's 3D pose within its environment. Therefore,
in this paper, we introduce a novel vision-based system leveraging depth data
to accurately establish the 3D locations of robotic joints. Specifically, we
prove the ability of the proposed system to enhance its current pose estimation
accuracy by jointly learning to forecast future poses. Indeed, we introduce the
concept of Pose Nowcasting, denoting the capability of a system to exploit the
learned knowledge of the future to improve the estimation of the present. The
experimental evaluation is conducted on two different datasets, providing
state-of-the-art and real-time performance and confirming the validity of the
proposed method on both the robotic and human scenarios
Microvascular oxygen delivery-to-utilization mismatch at the onset of heavy-intensity exercise in optimally treated patients with CHF
Sperandio PA, Borghi-Silva A, Barroco A, Nery LE, Almeida DR, Neder JA. Microvascular oxygen delivery-to-utilization mismatch at the onset of heavy-intensity exercise in optimally treated patients with CHF. Am J Physiol Heart Circ Physiol 297: H1720-H1728, 2009. First published September 4, 2009; doi:10.1152/ajpheart.00596.2009.-Impaired muscle blood flow at the onset of heavy-intensity exercise may transiently reduce microvascular O(2) pressure and decrease the rate of O(2) transfer from capillary to mitochondria in chronic heart failure (CHF). However, advances in the pharmacological treatment of CHF (e. g., angiotensin-converting enzyme inhibitors and third-generation beta-blockers) may have improved microvascular O(2) delivery to an extent that intramyocyte metabolic inertia might become the main locus of limitation of O(2) uptake ((V)over dot(O2)) kinetics. We assessed the rate of change of pulmonary (V)over dot(O2) ((V)over dot(O2p)), (estimated) fractional O(2) extraction in the vastus lateralis (similar to Delta[deoxy-Hb + Mb] by near-infrared spectroscopy), and cardiac output ((Q)over dot(T)) during high-intensity exercise performed to the limit of tolerance (Tlim) in 10 optimally treated sedentary patients (ejection fraction = 29 +/- 8%) and 11 controls. Sluggish (V)over dot(O2p) and (Q)over dot(T) kinetics in patients were significantly related to lower Tlim values (P < 0.05). the dynamics of Delta[deoxy-Hb + Mb], however, were faster in patients than controls [mean response time (MRT) = 15.9 +/- 2.0 s vs. 19.0 +/- 2.9 s; P < 0.05] with a subsequent response overshoot being found only in patients (7/10). Moreover, tau(V)over dot(O2)/MRT-[deoxy-Hb + Mb] ratio was greater in patients (4.69 +/- 1.42 s vs. 2.25 +/- 0.77 s; P < 0.05) and related to (Q)over dot(T) kinetics and Tlim (R = 0.89 and -0.78, respectively; P < 0.01). We conclude that despite the advances in the pharmacological treatment of CHF, disturbances in central and peripheral circulatory adjustments still play a prominent role in limiting (V)over dot(O2p) kinetics and tolerance to heavy-intensity exercise in nontrained patients.Fed Univ São Paulo UNIFESP, Dept Med, Div Resp Med, Pulm Funct & Clin Exercise Physiol Unit SEFICE, São Paulo, BrazilFed Univ São Paulo UNIFESP, Dept Med, Div Cardiol, São Paulo, BrazilFed Univ Sao Carlos UFSCar, Nucleus Res Phys Exercise, Cardiopulm Lab, Sao Carlos, SP, BrazilFed Univ São Paulo UNIFESP, Dept Med, Div Resp Med, Pulm Funct & Clin Exercise Physiol Unit SEFICE, São Paulo, BrazilFed Univ São Paulo UNIFESP, Dept Med, Div Cardiol, São Paulo, BrazilWeb of Scienc
Determination of anaerobic threshold through heart rate and near infrared spectroscopy in elderly healthy men
BACKGROUND:Aging leads to low functional capacity and this can be reversed by safe and adequate exercise prescription. OBJECTIVE:The aim of this study was to identify the anaerobic threshold (AT) obtained from the V-slope method as well as visual inspection of oxyhemoglobin ( O2Hb) and deoxyhemoglobin (HHb) curves and compare findings with the heteroscedastic (HS) method applied to carbon dioxide production ( CO2), heart rate (HR), and HHb data in healthy elderly men. A secondary aim was to assess the degree of agreement between methods for AT determination. METHOD:Fourteen healthy men (61.4±6.3 years) underwent cardiopulmonary exercise testing (CPX) on a cycle ergometer until physical exhaustion. Biological signals collected during CPX included: ventilatory and metabolic variables; spectroscopy quasi-infrared rays - NIRS; and HR through a cardio-frequency meter. RESULTS:We observed temporal equivalence and similar values of power (W), absolute oxygen consumption (O2 - mL/min), relative O2 ( mL.Kg - 1.min -1), and HR at AT by the detection methods performed. In addition, by the Bland-Altman plot, HR confirmed good agreement between the methods with biases between -1.3 and 3.5 beats per minute. CONCLUSIONS:(i) all detection methods were sensitive in identifying AT, including the HS applied to HR and (ii) the methods showed a good correlation in the identification of AT. Thus, these results support HR as valid and readily available parameter in determining AT in healthy elderly men.Conselho Nacional de Desenvolvimento CientÃfico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Universidade Federal do Rio de Janeiro School of Medicine Physical Therapy DepartmentUniversidade Federal de São Paulo (UNIFESP) Department of MedicineUniversity of Illinois College of Applied Health Sciences Physical Therapy DepartmentUniversidade Federal de Sao Carlos Physical Therapy Department Nucleus of Research in Physical ExerciseUNIFESP, Department of MedicineSciEL
Gait-Based Diplegia Classification Using LSMT Networks
Diplegia is a specific subcategory of the wide spectrum of motion disorders gathered under the name of cerebral palsy. Recent works proposed to use gait analysis for diplegia classification paving the way for automated analysis. A clinically established gait-based classification system divides diplegic patients into 4 main forms, each one associated with a peculiar walking pattern. In this work, we apply two different deep learning techniques, namely, multilayer perceptron and recurrent neural networks, to automatically classify children into the 4 clinical forms. For the analysis, we used a dataset comprising gait data of 174 patients collected by means of an optoelectronic system. The measurements describing walking patterns have been processed to extract 27 angular parameters and then used to train both kinds of neural networks. Classification results are comparable with those provided by experts in 3 out of 4 forms
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