Evaluación multicriterio para la optimización de redes de energía

Este trabajo propone una herramienta para ayudar en la toma de decisión de la planificación de redes de energía. Se incluye una evaluación multicriterio de los escenarios posibles de planificación considerando distintos criterios y ponderaciones. Para este cometido se usa la herramienta multiobjetivo discreta PROMETHEE y planos GAIA. El conjunto de escenarios se genera considerando incertidumbres que puede presentar el sistema. La simulación de la red eléctrica se lleva a cabo en la herramienta comercial OpenDSS. Para ilustrar la herramienta se ha tomado una red de la IEEE, donde se observan los beneficios del método propuesto. Los resultados obtenidos muestran que el tomar incertidumbres en el proceso de optimización de las redes de potencia, supone un gran aumento en la eficiencia de la red.Ministerio de Economía, Industria y Competitividad de España Proyecto CONFIGURA DPI2016-78338-

Importación de aceite de palma refinado y sostenible desde Ecuador a España

El presente documento se centra en un estudio de viabilidad de una operación de importación de aceite de palma refinado y sostenible desde Ecuador. En el actual escenario de crisis económica en el que nos encontramos en la mayoría de los países occidentales y, en el caso concreto de España, son muchas las empresas que se ven obligadas a salir al exterior para intentar compensar la baja demanda de sus países. Por ello nos decantamos por realizar una operación de importación de aceite de palma

Inter-Rater Variability in the Evaluation of Lung Ultrasound in Videos Acquired from COVID-19 Patients

12 páginas, 7 figuras, 1 tablaLung ultrasound (LUS) allows for the detection of a series of manifestations of COVID-19, such as B-lines and consolidations. The objective of this work was to study the inter-rater reliability (IRR) when detecting signs associated with COVID-19 in the LUS, as well as the performance of the test in a longitudinal or transverse orientation. Thirty-three physicians with advanced experience in LUS independently evaluated ultrasound videos previously acquired using the ULTRACOV system on 20 patients with confirmed COVID-19. For each patient, 24 videos of 3 s were acquired (using 12 positions with the probe in longitudinal and transverse orientations). The physicians had no information about the patients or other previous evaluations. The score assigned to each acquisition followed the convention applied in previous studies. A substantial IRR was found in the cases of normal LUS (κ = 0.74), with only a fair IRR for the presence of individual B-lines (κ = 0.36) and for confluent B-lines occupying 50% (κ = 0.50). No statistically significant differences between the longitudinal and transverse scans were found. The IRR for LUS of COVID-19 patients may benefit from more standardized clinical protocols.This research was partially funded by CDTI (Spanish acronym: Centre for Industrial Tech- nological Development), funding number COI-20201153. Partially supported by the Google Cloud Research Credits program with the funding number GCP19980904, by the project RTI2018-099118- A-I00 founded by MCIU/AEI/FEDER UE and by the European Commission–NextGenerationEU, through CSIC’s Global Health Platform (PTI Salud Global)

BIOVID: Micro espacios audiovisuales sobre biodiversidad

Se han realizado, editado y publicado microespacios de video alojados en la web www.ucm.es/segbiodiversidad/videos sobre aspectos relacionados con la biodiversidad, ecología y metodologías de seguimiento de aves, murciélagos, artrópodos y flora del campus de la Universidad Complutense de Madrid

Addictive and wonderful : the experience of reading the Harry Potter series

Aquest document està relacionat amb: Charming and bewitching : considering the Harry Potter serie

Effect of Graphene Flakes Modified by Dispersion in Surfactant Solutions on the Fluorescence Behaviour of Pyridoxine

The influence of graphene (G) dispersions in different types of surfactants (anionic, non-ionic, and cationic) on the fluorescence of vitamin B6 (pyridoxine) was studied. Scanning electron microscopy (SEM) was used to evaluate the quality of the G dispersions via measuring their flake thickness. The effect of surfactant type and concentration on the fluorescence intensity was analyzed, and fluorescence quenching effects were found for all of the systems. These turn out to be more intense with increasing both surfactant and G concentrations, albeit they do not depend on the G/surfactant weight ratio. For the same G concentration, the magnitude of the quenching follows the order: cationic > non-ionic ≥ anionic. The cationic surfactants, which strongly adsorb onto G via electrostatic attraction, are the most effective dispersing agents and they enable a stronger interaction with the zwitterionic form of the vitamin; the dispersing power improves with increasing the surfactant chain length. The fit of the experimental data to the Stern-Volmer equation suggests either a static or dynamic quenching mechanism for the dispersions in non-ionic surfactants, while those in ionic surfactants show a combined mechanism. The results that were obtained herein have been compared to those that were reported earlier for the quenching of another vitamin, riboflavin, to elucidate how the change in the vitamin structure influences the interactions with G in the surfactant dispersions

Maternal obesity and gestational diabetes are associated with DNA methylation alterations in the offspring throughout the first year of life

Objective: Obesity is a chronic metabolic disease of increasing prevalence and health importance in modern societies, which represents an added risk for the development of multiple pathologies. Moreover, epidemiological studies have shown how maternal obesity or gestational diabetes during pregnancy constitutes an important risk factor related to the appearance of cardiovascular and metabolic diseases in the offspring. Furthermore, this period of life is especially sensitive to extrinsic and intrinsic influence, so epigenetic remodelling may help explain the molecular mechanisms that underlie epidemiological findings. The main objective of this work was to determine the DNA methylation landscape of children born to mothers with obesity and gestational diabetes across their first year of life. Design and method: We have characterized the methylome of blood samples from a paediatric cohort of 39 subjects consisting of children born to mothers who suffered from obesity or obesity with gestational diabetes during pregnancy and healthy controls. We performed longitudinal measurements throughout the first year of life (0, 6 and 12 months; total N = 92) using Illumina Infinium MethylationEPIC BeadChip arrays to profile more than 770,000 CpG sites. The design allowed us to carry out both cross-sectional and longitudinal analyses in order to derive DNA methylation alterations associated with developmental and pathological-related epigenomics. Results: We have identified abundant DNA methylation alterations during child development from birth to 6 months and, to a lesser extent, until 12 months of age. At the same time, using cross-sectional analyses, we have identified DNA methylation biomarkers that discriminate children born to mothers who suffered from obesity or obesity with gestational diabetes during pregnancy compared to their healthy counterparts. Moreover, our longitudinal design allowed us to determine that these alterations are at least maintained during the first year of life. In addition, gene enrichment analyses revealed that these DNA methylation alterations are associated with regions and genes related to feeding behaviour, appetite, metabolism and cell signalling. Conclusions: Our results support the existence of an intrauterine-mediated maternal obesity effect with an impact on the childhood methylome and possible functional implications

Maternal obesity and gestational diabetes reprogram the methylome of offspring beyond birth by inducing epigenetic signatures in metabolic and developmental pathways

This work was supported by: the Spanish Association Against Cancer (Grant number PROYE18061FERN to M.F.F.), the Asturias Government (PCTI) cofounding 2018–2022/FEDER (Grant number IDI/2018/146 to M.F.F.), the Fundación General CSIC (Grant number 0348_CIE_6_E to M.F.F.), the Institute of Health Carlos III (Plan Nacional de I + D + I) cofounding FEDER (Grant numbers PI18/01527 and PI21/01067 to M.F.F. and A.F.F.; Grant numbers PI17/01517 and PI20/00269 to E.L.), and the Spanish Ministry of Science and Innovation (Grant number SGL2021-03-039/40 to M.F.F.) cofounding NextGenerationEU. J.R.T. is supported by a Juan de la Cierva fellowship from the Spanish Ministry of Science and Innovation (Grant number IJC2018-36825-I). J.J.A.L. is supported by the Spanish Association Against Cancer (Grant number PRDAS21642ALBA). R.F.P. and D.B.R. are supported by the Severo Ochoa program (Grant numbers BP17-114 and BP20-186). We also acknowledge support from the Institute of Oncology of Asturias (IUOPA, supported by Obra Social Cajastur Liberbank, Spain), the Health Research Institute of Asturias (ISPA-FINBA), the Health Research Institute INCLIVA and the Biomedical Research Networking Center on Rare Diseases (CIBERER-ISCIII).Peer reviewe