2,304 research outputs found

    Las relaciones internacionales de los municipios

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    Los procesos de apertura, democratización, descentralización y reforma estructural dentro de los países, aunado al fenómeno de la globalización, han generado un incremento en la interacción internacional dando lugar a un fenómeno en el que las unidades subnacionales (estados y municipios en el caso de México) han adquirido participación propia en el ámbito internacional con sus similares de otros países, al construir nuevos escenarios para el desarrollo nacional y lo cal

    Análisis del Programa de Educación, Salud y Alimentación (Progresa) en el municipio de San Felipe del Progreso, estado de México, 1998-2000

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    Desde su instrumentación, el Programa de Educación, Salud y Alimentación (Progresa), como el principal programa de combate a la pobreza extrema del gobierno federal, ha sido sujeto a una serie de evaluaciones institucionales y de organismos académicos, las cuales se han orientado principalmente a analizar los tres componentes que maneja el Progresa; el CIESAS, una de las instituciones de evaluación, ha determinado efectos negativos del programa en cuanto a la cohesión de los grupos sociales; sin embargo, existen otros efectos potencialmente negativos que afectan al gobierno municipal y que en determinado momento pueden llevar a que la población cuestione la legitimidad de la autoridad local. El presente artículo tiene como objetivo demostrar, con un caso de estudio, este problema de pérdida de presencia del gobierno local ante la población

    La Nueva Gerencia Pública: Flamante mito de un viejo paradigma

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    La administración pública es tan antigua como el Estado moderno. La administración también contribuye a su permanencia. La amplitud de los cuerpos burocráticos del Estado es una clara manifestación de su desarrollo. A pesar de las acometidas de las nuevas y viejas teorías anti estatales, la burocracia, ha logrado sobrevivir. Recientemente la gerencia pública se ha erigido como una pretendida innovación anti burocrática; sin embargo en el texto se demuestra su similitud con el cameralismo, que al igual que éste podrá desaparecer o pasar de moda, quedando en el olvido. Se considera lo riesgoso de importar modelos administrativos sin considerar las condiciones que les dieron origen y los efectos que pudieran causar al implantarse en un medio ambiente como el nuestro, tan diferente al original

    Dallas zoo hunts for escaped vulture

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    No Abstract. Vulture News Vol. 56 () 2007: pp.108-10

    Improvement of Emissions of internal Combustion Engines Using Reduction in Weight

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    This slide presentation for the Natural Sciences Poster Session at Parkland College identifies the health hazards associated with combustion engine emissions and summarizes a study conducted to determine if an engine with reduced weight would also reduce emissions

    Unstable Housing for Former Foster Youth in Santa Cruz County

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    A lot of former foster youth are currently homeless. Homeless youth face the financial burdens of having to afford the cost of application fees. Rental application fees range from 30to30 to 50. The Community Action Board of Santa Cruz County (CAB) is a non-profit organization made up of six separate anti-poverty initiatives that concentrate on addressing the needs of people with limited resources. The Transitional Age Youth Housing Navigation (TAY NAV) is a program that works with former foster youth. The purpose of my project was to help raise funds in order to help pay for rental applications. The project was a fundraiser in the form of a bake sale. People were able to make monetary donations. We anticipate for the fundraiser to be an annual event to be able to help former foster youth with rental application fees. The event was implemented on April 1st, 2023, and raised a total of $625. It is encouraged that TAY NAV continues to promote the annual bake sale on social media and in local newspapers

    Rational Design of an Antimicrobial Peptide

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    Background: Clostridioides difficile is a gram-positive, spore-forming anaerobic bacterium that is the leading cause of nosocomial infections. Due to its detergent-resistant spores and antibiotic resistance, C. difficile infection is an urgent threat since it is difficult to eliminate, allowing it to persist in healthcare institutions. Inadequate treatments available for this infection lead to the problem that C. difficile infection rates may rise in coming years due to an increase in hospital-acquired infections following the COVID-19 pandemic, and therefore the discovery of new antimicrobial compounds is of utmost importance. Antimicrobial peptides (AMPs) have become a promising alternative due to their unique mechanism, resulting in less antimicrobial resistance. Protein synthesis is a metabolic process that is a validated target for antibiotics. Initiation factor 1 (IF1) is a key component of protein synthesis and plays a key role in forming the pre-initiation complex with the 30S ribosome. The solution structure of Cd-IF1 has been determined and it consists of 5 β strands and 1 α helix forming a β-barrel arranged in a β1-β2-β3-α1-β4-β5 topology. Methods: Protein expression and purification of 15N-labeled Cd-IF1 were isolated using Fast Protein Liquid Chromatography (FPLC). NMR Titration studies of Cd-IF1 and the 30S ribosomal subunit were carried out at 298 K on a Bruker Ultrashield Plus 600 NMR spectrometer. Minimum Inhibitory Concentration (MIC) Assays were conducted for antimicrobial susceptibility testing. Cytotoxicity assays were conducted using Human Embryonic Kidney-293 (HEK-293) cells to determine the toxicity of the Cd-IF1 AMP. Results: The MIC for C. difficile was 0.13 mg/ml (66 μM) and for gram-positive species, the range of MIC was between 0.14 mg/ml and 0.37 mg/ml. The range MIC values for gram-negative species were between 1.0 – 1.5 mg/ml. The cytotoxicity assay determined that Cd-IF1 AMP showed no toxicity against HEK-293 cells. Conclusion: NMR titration studies of the 30S ribosomal subunit and Cd-IF1 reveal key interactions between the α -helical strand and the 30S ribosome. A peptide was derived from the α helical strand and tested against C. difficile and various bacteria for antimicrobial abilities. From these studies, the C. difficile antimicrobial peptide (AMP) displayed broad-spectrum inhibition against a wide range of bacteria but not HEK-293 cells and may be a candidate for antibiotic development

    Yttrium-90 Selective Internal Radiation Therapy with Glass Microspheres for Hepatocellular Carcinoma: Current and Updated Literature Review.

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    Hepatocellular carcinoma is the most common primary liver cancer and it represents the majority of cancer-related deaths in the world. More than 70% of patients present at an advanced stage, beyond potentially curative options. Ytrrium-90 selective internal radiation therapy (Y90-SIRT) with glass microspheres is rapidly gaining acceptance as a potential therapy for intermediate and advanced stage primary hepatocellular carcinoma and liver metastases. The technique involves delivery of Y90 infused glass microspheres via the hepatic arterial blood flow to the appropriate tumor. The liver tumor receives a highly concentrated radiation dose while sparing the healthy liver parenchyma due to its preferential blood supply from portal venous blood. There are two commercially available devices: TheraSphere® and SIR-Spheres®. Although, Y90-SIRT with glass microspheres improves median survival in patients with intermediate and advanced hepatocellular carcinoma and has the potential to downstage hepatocellular carcinoma so that the selected candidates meet the transplantable criteria, it has not gained widespread acceptance due to the lack of large randomized controlled trials. Currently, there are various clinical trials investigating the use of Y90-SIRT with glass microspheres for treatment of hepatocellular carcinoma and the outcomes of these trials may result in the incorporation of Y90-SIRT with glass microspheres into the treatment guidelines as a standard therapy option for patients with intermediate and advanced stage hepatocellular carcinoma

    1% left of 100: Taino History and Puerto Rican Identity

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    1% left of 100 is a documentary poetics research project exploring the confluence of identity, family, and language. Crafted in a hybrid format that mixes Spanish and English according to my personal idiolect, which is itself a product of my heritage as a Puerto Rican, Africa, native Taino American, this poem engages with exciting new approaches to thinking about race which liberate us from talking about physical features and takes us instead toward race as a social fact, a product of culture, history, and family. I seek to intervene in a narrative of American history that, though it teaches about first contact for Africans, and Spanish and Carribean peoples, seldom offers the voices of the natives who have occupied the islands before their arrival. I ask: who were those who self-identified as Taino? Where are the Taino? Can a people be erased? In similarity to Theresa Hak Kyung Cha’s Dictee, a memoir-poem about the Japanese occupation of Korea, I see to claim a feminist genealogy. I argue that language is part of going back to mother and grandmother and generations farther back. How have my mothers and their mothers spoken Spanish---the third most spoken language in the world. There are 90,000 words in its vocabulary, yet only 300 words originate from Taino’s native speech. Again, I argue against the outsized lament for purity, for Pure Taino people who are “extinct.” Instead, with my project I try to demonstrate that no one person can truly claim to be purely indigenously Taino. To hold a part of history isn’t only for DNA to choose for us. Who we are can be a cultural claim in body and soul. This project draws on historical archives as well as personal familial archives to tell a new kind of historical race narrative. 1% left of 100 integrates Taino and Puerto Rican history with my family language and history. I present early memories woven with digital images from family photo albums as I also integrate critical sources and historical documents. Telling my ancestors’ story as well as my own offers up a poetics of witness. The war of the Taino existence is stuck to repeat itself within me now. Connecting life to picture to archive is the linkage to making 1% left of 100

    The Road From Classical to Quantum Codes: A Hashing Bound Approaching Design Procedure

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    Powerful Quantum Error Correction Codes (QECCs) are required for stabilizing and protecting fragile qubits against the undesirable effects of quantum decoherence. Similar to classical codes, hashing bound approaching QECCs may be designed by exploiting a concatenated code structure, which invokes iterative decoding. Therefore, in this paper we provide an extensive step-by-step tutorial for designing EXtrinsic Information Transfer (EXIT) chart aided concatenated quantum codes based on the underlying quantum-to-classical isomorphism. These design lessons are then exemplified in the context of our proposed Quantum Irregular Convolutional Code (QIRCC), which constitutes the outer component of a concatenated quantum code. The proposed QIRCC can be dynamically adapted to match any given inner code using EXIT charts, hence achieving a performance close to the hashing bound. It is demonstrated that our QIRCC-based optimized design is capable of operating within 0.4 dB of the noise limit
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