Chemical Characterization of Natural Soiling on Solar Panel Glass Covers in an Urban Environment

Photovoltaic (PV) systems are an important source of renewable energy in the United States and the world. As PV systems become more commonly used in urban environments, PV soiling by urban air pollution must be investigated. This study investigates the effects of aging and urban air pollutant deposition on multiple nanotechnology-enabled coating materials, described as “self-cleaning”, “hydrophilic”, and “hydrophobic”, applied onto glass panels that were exposed to natural soiling at different tilt angles (30°, 45°, 60°). Light meter measurements in the field showed no significant differences among samples. UV-Vis analysis showed that new self-cleaning coating started with 3.9% lower transmittance values than other samples, but after 4 months of natural aging, the hydrophobic sample performed ~ 2% better than others. XPS results showed that although freshly-coated samples had distinct elemental compositions, those compositions became similar after 4 months of field deployment. Results from this study will help elucidate the reliability of additive coatings for the protection of PV systems in urban environments and bring insights into the chemical and physical processes associated with urban PV aging

CAUSES AND MANAGEMENT OF VIRAL EYE INFECTION

Introduction: The eye is a fascinating organ for several reasons. It is not only have a composite structure, however it is considered an immune-privileged organ. The anatomy of the eye is composed of the anterior and posterior parts, the line of division is posterior to the lens. The anterior chamber lies within the anterior segment and is an immuneprivileged anatomical location, this is due to the fact that the T-cell response in this area is suppressed This protects the eye from potentially destructive immune attacks however it also makes defence against infectious agents challenging, particularly where T-cell responses are critical for immunological defence. Viruses could get into the eye by direct inoculation, or through haematogenous or neuronal spread. The diagnoses of viral eye infections are usually clinical one, helped by taking a thorough history and performing ophthalmic examination. But in challenging cases the lab tests are essential. In this review, we will discuss the most recent evidence regarding Causes and management of viral eye infection Aim of work: In this review, we will discuss the most recent evidence regarding Causes and management of viral eye infection Methodology: We did a systematic search for Causes and management of viral eye infection using PubMed search engine (http://www.ncbi.nlm.nih.gov/) and Google Scholar search engine (https://scholar.google.com). All relevant studies were retrieved and discussed. We only included full articles. Conclusions: A wide range of of viruses can affect the eye and cause viral eye infections, either as a primary infection or reactivation. Some affect the eye directly while the others indirectly but may still manifest with eye disease. One virus may affect several parts of the eye, while different viruses may cause the same eye disease. This could complicate the clinical diagnosis of viral eye disease, but the lab tests like PCR and antibody tests could assist in challenging cases where there may be diagnostic dilemma. The HIV epidemic has had an huge impact on ophthalmology clinics, this is because the virus can cause different eye diseases, and the associated decrease in cell-mediated immunity makes the person highly susceptible to opportunistic viral eye infections, sometimes with severe morbidity. There could be other viruses that may affect the eye that we did not discuss. Key words: Causes, management, viral eye infection

Survival implications vs. complications: unraveling the impact of vitamin D adjunctive use in critically ill patients with COVID-19—A multicenter cohort study

BackgroundDespite insufficient evidence, vitamin D has been used as adjunctive therapy in critically ill patients with COVID-19. This study evaluates the effectiveness and safety of vitamin D as an adjunctive therapy in critically ill COVID-19 patients.MethodsA multicenter retrospective cohort study that included all adult COVID-19 patients admitted to the intensive care units (ICUs) between March 2020 and July 2021. Patients were categorized into two groups based on their vitamin D use throughout their ICU stay (control vs. vitamin D). The primary endpoint was in-hospital mortality. Secondary outcomes were the length of stay (LOS), mechanical ventilation (MV) duration, and ICU-acquired complications. Propensity score (PS) matching (1:1) was used based on the predefined criteria. Multivariable logistic, Cox proportional hazards, and negative binomial regression analyses were employed as appropriate.ResultsA total of 1,435 patients were included in the study. Vitamin D was initiated in 177 patients (12.3%), whereas 1,258 patients did not receive it. A total of 288 patients were matched (1:1) using PS. The in-hospital mortality showed no difference between patients who received vitamin D and the control group (HR 1.22, 95% CI 0.87–1.71; p = 0.26). However, MV duration and ICU LOS were longer in the vitamin D group (beta coefficient 0.24 (95% CI 0.00–0.47), p = 0.05 and beta coefficient 0.16 (95% CI −0.01 to 0.33), p = 0.07, respectively). As an exploratory outcome, patients who received vitamin D were more likely to develop major bleeding than those who did not [OR 3.48 (95% CI 1.10, 10.94), p = 0.03].ConclusionThe use of vitamin D as adjunctive therapy in COVID-19 critically ill patients was not associated with survival benefits but was linked with longer MV duration, ICU LOS, and higher odds of major bleeding

Oral semaglutide adequate glycaemia control with safe cardiovascular ‎profile

BackgroundType 2 diabetes is a chronic and progressive disease that ‎associated with series complication such as major adverse ‎cardiovascular events. Adequate glycaemic control proven ‎to reduce this risk. Orally administered semaglutide ‎promising medication in managing patient with type 2 ‎diabetes.‎AimsTo assess the cardiovascular safety and efficacy of semaglutide, a recently approved glucagon-like peptide 1 receptor agonist (GLP-1 RA) for type 2 diabetes.Methods Pub Med, ‎Google Scholar, and EBSCO ‎ databases were ‎systematically search for relevant articles. The terms‎ diabetes‎, Glucagon-like peptide, semaglutide‎ were used. Out of hundred twenty-two records, only ‎four fulfilled ‎the inclusion criteria.Results Four placebo-controlled studies with oral semaglutide ‎were included. Single study concern about the cardiovascular safety of oral semaglutide ‎and showed that, ‎compared with placebo, semaglutide ‎ was not associated ‎with increased in the cardiovascular events. On the other ‎hand, the remaining trials shown that, semaglutide ‎ can ‎effectively control the blood glucose as evident by ‎reduction in HA1c.ConclusionOral semaglutide can effectively and safely lower blood glucose without increase in the major adverse ‎cardiovascular events‎‎ (MACE).

Proline-Induced Modifications in Morpho-Physiological, Biochemical and Yield Attributes of Pea (<i>Pisum sativum</i> L.) Cultivars under Salt Stress

Climate change is aggravating soil salinity, causing huge crop losses around the globe. Multiple physiological and biochemical pathways determine the ability of plants to tolerate salt stress. A pot experiment was performed to understand the impact of proline levels, i.e., 0, 10, 20 mM on growth, biochemical and yield attributes of two pea (Pisum sativum L.) cultivars (cv. L-888 and cv. Round) under salt stress (150 mM) along with control (0 mM; no stress). The pots were filled with river-washed sand; all the plants were irrigated with full-strength Hoagland’s nutrient solution and grown for two weeks before application of salt stress. Foliar spray of proline was applied to 46-day-old pea plants, once a week till harvest. Data for various growth and physio-biochemical attributes were collected from 70-day-old pea plants. Imposition of salt stress significantly checked growth, gas exchange characteristics [net CO2 assimilation rate (A), transpiration rate (E), stomatal conductance (gs)], total soluble proteins, concentration of superoxide dismutase (SOD), shoot and root K+ and Ca2+ contents, while sub-stomatal CO2 concentration (Ci), coefficient of non-photochemical quenching (qN), non-photochemical quenching (NPQ), concentration of catalase (CAT) and peroxidase (POD), free proline, and shoot and root Na+ contents increased substantially. Foliar application of proline significantly improved growth, yield, A, gs, activity of POD, and shoot and root K+ and Ca2+ contents, while decreased NPQ values in both pea cultivars under stress and non-stress conditions. Moreover, both pea cultivars showed significant differences as cv. Round exhibited a higher rate of growth, yield, gas exchange, soluble proteins, CAT activity, free proline, shoot and root K+ and Ca2+ contents compared to L-888. Hence, the outcomes of this study pave the way toward the usage of proline at 20 mM, and cv. Round may be recommended for saline soil cultivation

Proline-Induced Modifications in Morpho-Physiological, Biochemical and Yield Attributes of Pea (Pisum sativum L.) Cultivars under Salt Stress

Climate change is aggravating soil salinity, causing huge crop losses around the globe. Multiple physiological and biochemical pathways determine the ability of plants to tolerate salt stress. A pot experiment was performed to understand the impact of proline levels, i.e., 0, 10, 20 mM on growth, biochemical and yield attributes of two pea (Pisum sativum L.) cultivars (cv. L-888 and cv. Round) under salt stress (150 mM) along with control (0 mM; no stress). The pots were filled with river-washed sand; all the plants were irrigated with full-strength Hoagland&rsquo;s nutrient solution and grown for two weeks before application of salt stress. Foliar spray of proline was applied to 46-day-old pea plants, once a week till harvest. Data for various growth and physio-biochemical attributes were collected from 70-day-old pea plants. Imposition of salt stress significantly checked growth, gas exchange characteristics [net CO2 assimilation rate (A), transpiration rate (E), stomatal conductance (gs)], total soluble proteins, concentration of superoxide dismutase (SOD), shoot and root K+ and Ca2+ contents, while sub-stomatal CO2 concentration (Ci), coefficient of non-photochemical quenching (qN), non-photochemical quenching (NPQ), concentration of catalase (CAT) and peroxidase (POD), free proline, and shoot and root Na+ contents increased substantially. Foliar application of proline significantly improved growth, yield, A, gs, activity of POD, and shoot and root K+ and Ca2+ contents, while decreased NPQ values in both pea cultivars under stress and non-stress conditions. Moreover, both pea cultivars showed significant differences as cv. Round exhibited a higher rate of growth, yield, gas exchange, soluble proteins, CAT activity, free proline, shoot and root K+ and Ca2+ contents compared to L-888. Hence, the outcomes of this study pave the way toward the usage of proline at 20 mM, and cv. Round may be recommended for saline soil cultivation

Hemarthria compressa—Aspergillus niger—Trichoderma pseudokoningii Mediated Trilateral Perspective for Bioremediation and Detoxification of Industrial Paper Sludge

The present study was carried out to evaluate the effects of different fungal species on the metal uptake from paper sludge by Hemarthria compressa L. Paper sludge (PS) in various concentrations (0, 30% and 60%) were used with four treatments of two fungal species (F0 = Control, F1 = Aspergillus niger, F2 = Trichoderma pseudokoningii, F3 = A. niger + T. pseudokoningii). Paper sludge as rooting medium steadily influenced growth and physio-biochemical attributes of H. compressa in F0. Results revealed discrete variations in growth attributes with different PS concentrations and each fungal treatment. The maximum damages in ionic homeostasis (Na+, K+, Ca2+, Mg2+) due to PS toxicity were evident in parallel with declined chlorophyll concentration. The highest growth, total chlorophyll and biomass of the plants were observed when PS was treated with combined fungal strains (F3). Translocation factor decreased with F3 that is indicative of changes in Cd, Pb, and Cu movement to shoot from root. The plants with combined fungal treatment also showed greater catalase (CAT), superoxide dismutase (SOD), and peroxidase (POD) activity. Ions, such as Ca, Mg, and Na, also increased gradually with combined fungal treatment. The correlation matrix displayed a close association among diverse fungal and PS levels with multiple plant attributes. PCA-Biplot confirmed the outcome of correlational analyses among different characters of H. compressa. The combined fungal mediate the extraction of heavy metals from the paper sludge by H. compressa recommends the high accumulation of heavy metal (HM) and possible reutilization of metal free sludge as a fertilizer, for application in cultivated fields. Furthermore, the effects of fungal species on HM attenuation in PS are linear and can be used in different habitats. Advancement in such research work will also be helpful in understanding the mechanisms and enhancing the ability of other native microbes to remediate metals

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results: NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year. Conclusion: As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population

International Nosocomial Infection Control Consortium report, data summary of 50 countries for 2010-2015: Device-associated module

•We report INICC device-associated module data of 50 countries from 2010-2015.•We collected prospective data from 861,284 patients in 703 ICUs for 3,506,562 days.•DA-HAI rates and bacterial resistance were higher in the INICC ICUs than in CDC-NHSN's.•Device utilization ratio in the INICC ICUs was similar to CDC-NHSN's. Background: We report the results of International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2010-December 2015 in 703 intensive care units (ICUs) in Latin America, Europe, Eastern Mediterranean, Southeast Asia, and Western Pacific. Methods: During the 6-year study period, using Centers for Disease Control and Prevention National Healthcare Safety Network (CDC-NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 861,284 patients hospitalized in INICC hospital ICUs for an aggregate of 3,506,562 days. Results: Although device use in INICC ICUs was similar to that reported from CDC-NHSN ICUs, DA-HAI rates were higher in the INICC ICUs: in the INICC medical-surgical ICUs, the pooled rate of central line-associated bloodstream infection, 4.1 per 1,000 central line-days, was nearly 5-fold higher than the 0.8 per 1,000 central line-days reported from comparable US ICUs, the overall rate of ventilator-associated pneumonia was also higher, 13.1 versus 0.9 per 1,000 ventilator-days, as was the rate of catheter-associated urinary tract infection, 5.07 versus 1.7 per 1,000 catheter-days. From blood cultures samples, frequencies of resistance of Pseudomonas isolates to amikacin (29.87% vs 10%) and to imipenem (44.3% vs 26.1%), and of Klebsiella pneumoniae isolates to ceftazidime (73.2% vs 28.8%) and to imipenem (43.27% vs 12.8%) were also higher in the INICC ICUs compared with CDC-NHSN ICUs. Conclusions: Although DA-HAIs in INICC ICU patients continue to be higher than the rates reported in CDC-NSHN ICUs representing the developed world, we have observed a significant trend toward the reduction of DA-HAI rates in INICC ICUs as shown in each international report. It is INICC's main goal to continue facilitating education, training, and basic and cost-effective tools and resources, such as standardized forms and an online platform, to tackle this problem effectively and systematically