Employing bibliometric analysis on research published in Pakistan Journal of Medical and Health Sciences from 2019 – 2009.

Introduction: Pakistan Journal of Medical and Health Sciences is peer review and indexed in the Scopus-Elsevier database. This study signifies the participation of (PJMHS) in the research productivity, published from 2019 - 2009. Material and Methods: The records of the published data retrieved from PJMHS website and Scopus-Elsevier database for tabulation in MS Office Excel Sheet. Frequency of publications, type of documents, usage of pages, citations, and association of the first author with their countries. Results: Total 3817 documents written by 15401 (4%) authors in seven categories published in 43 issues. An average of (2.8%) pages consumed with getting of 896 (23.4%) citations in publications. Collaboration of three authors contributed 1339 (36.6%) documents and got first slot, and four authors 3344 (21.7%) added 836 (22%) of documents. The first authors affiliated with 29 countries around the globe participated in publications; Pakistan with 3484 (91%), Iran 79 (2%), Indonesia 77 (2%), and Kingdome of Saudi Arabia 65 (1.7%) stand on top places. Conclusion: Pakistan Journal of Medical and Health Sciences (PJMHS) is a peer-reviewed journal published continuously and facilitates research communities of medical and health sciences to get their attention in sharing ideas on a reciprocal basis from similar specialties or sub-specialties of common disciplines

A Review Articles: Pantoea agglomerans in UTI- It is Bacteria Caused Urinary Tract Infection and Genomic Analysis related with Bacterial Resistance

Pantoea Spp. is a plant bacteria that has been identified as an emerging pathogen in humans related with outbreaks and many clinical infections. It is referred to as a "mystery bacterium of evil and good" since it may cause both bad and good. With the proposed investigation, the researchers hope to uncover a significant risk component that is connected with reoccurring urinary tract infections (UTI). They also hope to identify bacterial reasons and antibiotic susceptibility profiles that can be used to lower the threat of reinfection and prevent complications associated with recurrent UTI. In the existence of risk variables, the likelihood of developing a UTI increases; also, a correct susceptibility pattern increases the likelihood of achieving therapeutic effectiveness and preventing illness complications. Because of its capacity to infect immunocompromised persons and produce severe illness as a consequence of its multi - drug resistance, Pantoeasppregard is considered to be a dangerous opportunistic pathogen. In this paper we are going to focus on related bacteria, pathogenicity, resistance genes, classification

Morphofunctional ecology of 15 seedlings species from an Atlantic Rainforest of Sergipe, Brazil

Atlantic Rainforest of Sergipe State is now fragmented and reduced to only 9% of its original cover. The knowledge of seedlings’ morphofunctional ecology in this ecosystem is essential to taxonomic, forestry and ecological purposes, since the ability to recognize seedlings on field is required to understand the natural regeneration and plant succession dynamics. In this study, the germination and seedlings morphology of 15 species of aSergiperemanescentForestwere described and illustrated. Besides, relationship among seed biometry, seedling morphology and ecological traits were analyzed. From the total of species analyzed 40% was classified as phanerocotylar epigeal with foliaceous cotyledons, 26.7% as cryptocotylar hypogeal with reserve storage cotyledons, 26.7% as phanerocotylar epigeal with reserve storage cotyledons and 6.6% as phanerocotylar hypogeal with reserve storage cotyledons. The relationships among seed biometry, seedling morpho-functional type and species ecological attributes found in species analyzed are similar to those obtained in other tropical forests. This result suggests that the morphology of seedlings is strongly driven by species regeneration niche.Em Sergipe a Floresta Atlântica encontra-se hoje fragmentada e reduzida a apenas 9% da sua cobertura original. O estudo da ecologia morfofuncional de plântulas nesse ecossistema é importante para a taxonomia, silvicultura e ecologia, possibilitando a identificação das plântulas no campo, requisito necessário para o entendimento da regeneração e sucessão vegetal. Neste estudo, foram descritas a germinação e a morfologia de plântulas de 15 espécies de um remanescente florestal sergipano, sendo também analisadas as relações entre biometria das sementes, morfologia das plântulas e outros atributos ecológicos. Do total de espécies analisadas 40% foram classificadas como fanero-epígeo-foliáceas, 26,7%, como cripto-hipógeo-armazenadoras, 26,7% como fanero-epígeo-armazenadoras e 6,6% como fanero-hipógeo-armazenadoras. A existência de relações entre a biometria da semente, o tipo morfofuncional de plântula e os atributos ecológicos das espécies analisadas corroborou os resultados obtidos em outras florestas tropicais, indicando que a morfologia da plântula é fortemente direcionada pelas características do nicho de regeneração.São Cristóvão, S

Multiple sclerosis following bariatric surgery: A report of five cases

Multiple sclerosis (MS) is a debilitating chronic inflammatory demyelinating disease that affects the central nervous system. The underlying cause of multiple sclerosis is unknown, yet there are various predisposing factors. Currently, bariatric surgery is an increasingly common solution for obesity. It has been reported that bariatric procedures result in miscellaneous neurological complications. To the best of our knowledge, this is the first case series to report the occurrence of MS following bariatric surgery. Here we report the cases of five patients who were recruited for inclusion following neurological examination, complete cerebrospinal fluid (CSF) study, enhanced cranial as well as spinal cord magnetic resonance (MR) images. Diagnosis of multiple sclerosis was made based on McDonalds criteria (2010). All cases were diagnosed with relapsing-remitting form of multiple sclerosis (RRMS) after various types of bariatric surgeries

Relationship Between Glycated Haemoglobin and Carotid Atherosclerotic Disease Among Patients with Acute Ischaemic Stroke

Objectives: This study aimed to determine the relationship between glycaemic control and carotid atherosclerotic disease among patients with acute ischaemic stroke (AIS). Methods: This retrospective cross-sectional study took place in the Neurology Department of King Fahad Hospital of University, Khobar, Saudi Arabia, from April to October 2017. Data were collected from the medical records of 244 patients with a diagnosis of AIS confirmed by computed tomography. Doppler ultrasounds of the carotid artery were performed to determine the presence of increased carotid intima media thickness (CIMT) and plaques. Results: Significantly higher mean glycated haemoglobin (HbA1c) levels were noted in cases with high CIMT values (P = 0.002), but not in cases with carotid plaques (P = 0.360). In addition, there was a significant association between diabetes mellitus (DM) and high CIMT (P = 0.045), but not with carotid plaques (P = 0.075). Finally, while dyslipidaemia and age were independently correlated with high CIMT values (P = 0.034 and 0.050 each). Conclusion: High HbA1c levels were associated with high CIMT values, but not with carotid plaques. Therefore, HbA1c levels may be useful as an indirect marker of the initial stages of carotid artery atherosclerosis. Keywords: Glycated Hemoglobin A1c; Diabetes Mellitus; Carotid Intima-Media Thickness; Atherosclerotic Plaque; Stroke

Employing bibliometric analysis on research published in Pakistan Journal of Medical and Health Sciences from 2019 – 2009.

Introduction: Pakistan Journal of Medical and Health Sciences is peer review and indexed in the Scopus-Elsevier database. This study signifies the participation of (PJMHS) in the research productivity, published from 2019 - 2009. Material and Methods: The records of the published data retrieved from PJMHS website and Scopus-Elsevier database for tabulation in MS Office Excel Sheet. Frequency of publications, type of documents, usage of pages, citations, and association of the first author with their countries. Results: Total 3817 documents written by 15401 (4%) authors in seven categories published in 43 issues. An average of (2.8%) pages consumed with getting of 896 (23.4%) citations in publications. Collaboration of three authors contributed 1339 (36.6%) documents and got first slot, and four authors 3344 (21.7%) added 836 (22%) of documents. The first authors affiliated with 29 countries around the globe participated in publications; Pakistan with 3484 (91%), Iran 79 (2%), Indonesia 77 (2%), and Kingdome of Saudi Arabia 65 (1.7%) stand on top places. Conclusion: Pakistan Journal of Medical and Health Sciences (PJMHS) is a peer-reviewed journal published continuously and facilitates research communities of medical and health sciences to get their attention in sharing ideas on a reciprocal basis from similar specialties or sub-specialties of common disciplines

Interfacility critical care transfers in Saudi Arabia:measuring adverse events, mortality comparison and consensus on interventions in adult critical patients transferred by paramedics

Introduction: paramedics conducting interfacility transfer of critically-ill patients is one of the existing models in interfacility transfer. The paramedic model is available in multiple countries, including the Kingdom of Saudi Arabia. Paramedics’ expanded scope of practice has allowed them to transport, monitor and intervene with complex patients. This PhD thesis is designed to evaluate the safety of the paramedic model in Saudi Arabia conducting interfacility transportation of critically-ill patients. Method: the PhD thesis is mixed methods. A systematic literature review was conducted to examine literature on the safety of paramedics in interfacility transfers. A retrospective chart review was conducted to examine the incidence, predictors and pattern of adverse events seen in interfacility transfers by paramedics in Saudi Arabia. Following this, a retrospective chart review of interfacility transfers by physicians to the same institution was conducted to compare in-hospital mortality and 30-days survival in both groups. Finally, an expert survey was conducted to examine the consensus of paramedics’ intervention to adverse events seen in interfacility critical care transfers. Results: the literature showed that the frequency of adverse events seen by paramedics in interfacility transfers ranges from 5.1% to 18%. The rate of adverse events in adult critical patients transferred by paramedics to a tertiary care facility in Saudi Arabia was 13.7%, in-hospital mortality was 30.4% and 30-days survival was 68.1%. There is no significant difference regarding in-hospital mortality or 30-days survival between the paramedic and physician models. The paramedics’ interventions in interfacility adult critically-ill patients were rated appropriate by the majority of the experts in 86.8% of cases; the probability of an intervention to be appropriate was 84.9%. Conclusion: paramedics with appropriate training and skill can safely transfer critical interfacility adult patients. The mortality outcomes in the paramedic model are comparable to the physician model

Incidence and predictors of adverse events and outcomes for adult critically ill patients transferred by paramedics to a tertiary care medical facility

Objective: The aim of this study was to determine the incidence of adverse events and patients’ outcomes in inter‑facility critical care transfers by paramedics. Methods: We conducted a retrospective cohort study of adults undergoing inter‑facility transfer to a tertiary medical facility by paramedics. We included all patients transferred between 1st June, 2011 and 31st December, 2014. The primary outcome is in‑transit adverse event and the secondary outcome is in‑hospital mortality. Multiple logistic regression models were fitted to assess predictor variables for adverse events and in‑hospital mortality. Results: The incidence of adverse events was 13.7% (31/227 patients had in‑transit adverse event); the most common adverse events reported were desaturation and hypotension. A unit increase in risk score for transported patients (RSTP) significantly increased the occurrence of adverse events (adjusted odds ratio [OR]: 1.36, 95% confidence interval [CI]: 1.07–1.72 and adjusted P = 0.01). Compared to medical patients, cardiac patients were less likely to develop adverse events (adjusted OR: 0.117, 95% CI: 0.02–0.52 and adjusted P < 0.01). The in‑hospital mortality was 30.4% and 30-day survival was 68.1%. For two patients whose age differed by 1 year, the older patient was more likely to die (adjusted OR: 1.03, 95% CI: 1.01–1.05 and P < 0.01) and a unit increase in RSTP significantly increased occurrence of in‑hospital mortality (adjusted OR: 1.30, 95% CI: 1.0–1.60 and P = 0.01). Conclusion: The incidence of adverse events was 13.7%. The most common observed adverse events were desaturation and hypotension. In‑hospital mortality was 30.4% and 30-day survival was 68.1%

Independent and Combined Effects of Probiotics and Prebiotics as Supplements or Food-Rich Diets on a Propionic-Acid-Induced Rodent Model of Autism Spectrum Disorder

The link between nutrition and autism spectrum disorder (ASD) as a neurodevelopmental condition, which is clinically presented as significant delays or deviations in interaction and communication, has provided a fresh point of view and signals that nutrition may play a role in the etiology of ASD, as well as playing an effective role in treatment by improving symptoms. In this study, 36 male albino rat pups were used. They were randomly divided into five groups. The control group was fed only a standard diet and water for the 30 days of the experiment. The second group, which served as a propionic acid (PPA)-induced rodent model of ASD, received orally administered PPA (250 mg/kg body weight (BW)) for 3 days, followed by feeding with a standard diet until the end of the experiment. The three other groups were given PPA (250 mg/kg body weight (BW)) for 3 days and then fed a standard diet and orally administered yogurt (3 mL/kg BW/day), artichokes (400 mL/kg BW/day), and a combination of Lacticaseibacillus rhamnosus GG at 0.2 mL daily (1 × 109 CFU; as the probiotic of yogurt) and luteolin (50 mg/kg BW/day; as the major antioxidant and anti-inflammatory ingredient of artichokes) for 27 days. Biochemical markers, including gamma-aminobutyric acid (GABA), reduced glutathione (GSH), glutathione peroxidase (GPx1), tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and interleukin-10 (IL-10), were measured in brain homogenates in all groups. The data showed that while PPA demonstrated oxidative stress and neuroinflammation in the treated rats, yogurt, Lacticaseibacillus rhamnosus GG as a probiotic, and luteolin as a prebiotic ingredient in artichokes were effective in alleviating the biochemical features of ASD. In conclusion, nutritional supplementation seems to be a promising intervention strategy for ASD. A combined dietary approach using pro- and prebiotics resulted in significant amelioration of most of the measured variables, suggesting that multiple interventions might be more relevant for the improvement of biochemical autistic features, as well as psychological traits. Prospective controlled trials are needed before recommendations can be made regarding the ideal ASD diet