The impact of organisational culture and leadership on performance improvement in Iraq

In 2013, the World Bank ranked Iraq 165 out of 185 countries in its overall “ease of doing business” category. Transparency International ranked Iraq 169 out of 176 in its 2012 Corruption Perception Index (BEBA, 2013). This reflects the poor performance of the public sector organisations responsible for the delivery of the various services in Iraq. By looking at the literature, it is clear that organisational culture and leadership have a significant impact on the performance of organisations. Thus, this makes them important factors that need to be taken into consideration when reforming public sector performance in the developing world. However, there has not been any research that discusses this relationship from the context of the public sector in Iraq. Therefore, this paper aims at expanding the base of knowledge and empirically tests the impact of leadership, people and organisational culture on a public sector organisation’s performance in Iraq. The study has used a public service “Practices & Performance” Benchmarking tool called PROBE, which stands for PROmoting Business Excellence, to assess the current organisational leadership and people practices of a government organisation and has benchmarked them to best practices of world-class organisations. Interviews have also been conducted, first with the staff members to gain consensus on the assessment results. Then the organisation’s customers (who are mainly contractors) have also been interviewed to understand their level of satisfaction with the current practices of the organisation. The result derived from the interviews accord with the results generated by the PROBE tool. The assessment result has showed how poor leadership and people practices have led to a weak overall organisational performance. This result supports previous studies and confirms the impact of organisational culture, people and leadership on the performance of organisations

Some physiological and nutritional responses of common carp Cyprinus carpio juveniles to osmotic stress

The effect of salinity (<1, 7, and 15 ppt) on some physiological and nutritional parameters of common carp (Cyprinus carpio) juveniles was examined in two trials. In the first trial, the activity of the common liver enzymes (alkaline phosphatase ALP, Aspartate transaminase AST, and Alanine transaminase ALT) in the blood serum, and total plasma protein level on the 1st, 7th, and 14th day of exposure, using 90 fish (14.05±2.01g) were studied. In the second trial, the growth and feed efficiency performance (weight gain WG, relative growth rate RGR, specific growth rate SGR, and feed conversion ratio FCR), and apparent digestibility coefficients ADCs of dry matter, nutrients, and energy were investigated during ten ten-week rearing period using another 90 fish (15.71±1.59 g). The results showed that the activity of the ALP was increased significantly (P?0.05) with increasing salinity on the 1st day, and continued to the following 7th and 14th day periods. AST in 7 and 15 ppt showed significantly (P?0.05) higher activity levels compared with 1 ppt on the 1st day, similar differences were found on the 7th and 14th day for 15 ppt, but not for 7 ppt during the same periods. ALT exhibited significantly (P?0.05) higher activity in 7 and 15 ppt relative to <1 ppt during all periods. Total plasma protein fluctuated slightly (P>0.05) on the 1st and 7th day and decreased significantly (P?0.05) in 15 ppt only on the 14th day. Significantly (P?0.05) better specific growth rate SGR and feed conversion ratio FCR were observed in the lowest salinity (<1 ppt) while the worst in the highest (15 ppt). The ADCs of dry matter, nutrients, and digestible energy were decreased significantly (P?0.05) with increasing water salinity

Feasibility study of achieving reliable electricity supply using hybrid power system for rural primary schools in Iraq: a case study with umm qasr primary school

Electrical power is considered as a significant part of contemporary life, and an essential element for development. Fossil fuels have been utilized since the beginning of the twentieth century for electricity generation. However, fossil fuels depletion at the escalating pace as well as their formidable negative implications upon ecosystem contributed to increasing interest in harnessing renewable energy sources for producing electric power to meet the growing demand worldwide. In Iraq, the electrical supply is not sufficient to supply 12 hours a day of electricity. Many rural areas, particularly their schools are suffering from the electricity shortage such as Umm Qasr Primary School that located 20 km away from the city centre of Karbala city in the middle of Iraq. In order to overcome this issue, this paper proposes a hybrid system which relies on renewable resources and the local grid to electrify Umm Qasr Primary School. Various combinations of energy resources have been analysed by using HOMER software to estimate an optimum hybrid system. The analysis illustrates that the optimal configuration of the projected system is composed of 22.4 kW PV modules, 59 batteries, and 5738kWh purchased from the local grid which has reduced the net present cost(NPC)from US$163791 the current situation to US$60,420 for the proposed system. The simulation findings also demonstrate that detrimental emissions have been reduced significantly

Effect of dietary inclusion of raw and fermented hornwort, Ceratophyllum demersum, on growth performance and digestibility of young grass carp, Ctenopharyngodon idella Val.

A 12-week feeding experiment was conducted to evaluate the growth performance, feed efficiency, digestibility and carcass composition of young grass carp Ctenopharyngodon idella (Val, 1844) (4.03±0.16 g) fed on a control diet and two experimental diets (38.5% crude protein). The experiment aimed to assess the utilization of raw hornwort Ceratophyllum demersum (HR) and fermented (HF) by adding 20% of each of the alternative ingredients separately to the control diet (C) to completely compensate barley, a portion of wheat bran and 20% of fish meal. Results indicated that all growth and feed efficiency parameters among groups were no significantly different (P>0.05) in specific growth rate (SGR), food conversion ratio (FCR), protein efficiency ratio (PER), and protein productive value (PPV) of fish fed HR and HF with the control diet. There was no effect (P>0.05) in stimulating digestibility (ADCtotal) when HR and HF were added to the diet. Both HR and HF produced significantly (P0.05) by the inclusion of raw or fermented hornwort. Whereas, the moisture, protein and lipid levels in carcass were similar (P>0.05) in all groups, except for the control diet (C), which recorded the highest ash level (P<0.05). In conclusion, the incorporation of raw or fermented hornwort up to 20% level was found to be not suitable, and there were adverse effects on the growth and feed efficiency of experimental fish

Hypoxia-Modified Cancer Cell Metabolism

While oxygen is critical to the continued existence of complex organisms, extreme levels of oxygen within a system, known as hypoxia (low levels of oxygen) and hyperoxia (excessive levels of oxygen), potentially promote stress within a defined biological environment. The consequences of tissue hypoxia, a result of a defective oxygen supply, vary in response to the gravity, extent and environment of the malfunction. Persistent pathological hypoxia is incompatible with normal biological functions, and as a result, multicellular organisms have been compelled to develop both organism-wide and cellular-level hypoxia solutions. Both direct, including oxidative phosphorylation down-regulation and inhibition of fatty-acid desaturation, and indirect processes, including altered hypoxia-sensitive transcription factor expression, facilitate the metabolic modifications that occur in response to hypoxia. Due to the dysfunctional vasculature associated with large areas of some cancers, sections of these tumors continue to develop in hypoxic environments. Crucial to drug development, a robust understanding of the significance of these metabolism changes will facilitate our understanding of cancer cell survival. This review defines our current knowledge base of several of the hypoxia-instigated modifications in cancer cell metabolism and exemplifies the correlation between metabolic change and its support of the hypoxic-adapted malignancy

Role of anti-inflammatory interleukin 10 in asymptomatic heartworm infection (Dirofilariasis) in dogs

Background: Dirofilaria immitis causes heartworm disease (HWD), a vector-borne zoonotic disease that primarily affects dogs and cats. Occasionally, human beings were reported to be infected as well. The current study aims to discover the asymptomatic dirofilariasis infection in dogs. In addition, to determine the prevalence of heartworm disease and the role of anti-inflammatory interleukin 10 (IL10) in developing the disease. Household dogs were selected from 10 veterinary clinics throughout Basrah, south of Iraq.Methods: The study included 117 dogs older than 12 months, none of them had received heartworm vaccinations, and all of them lived in their owners’ houses for at least 9 months. Animal ethics instructions were followed after the owner’s consent was obtained.  Physical and biochemical examinations were conducted including the examination of circulating antigens of microfilaria. The levels of anti-inflammatory IL10 and pro-inflammatory IL17, IL4, and IFN-γ were measured using ELISA tests. Descriptive statistics were used to evaluate the prevalence and the clinical and immunological results of the study.Results: Canine heartworm disease prevalence was 29.05% (34 out of 117). The physical examination showed normal vital signs for both infected and non-infected dogs. A significant elevation in the total WBC count was noticed in the infected group.  On the other hand, a significant decrease in RBCs count and hemoglobin was found in the infected group. There were neither changes in the platelet count nor the liver enzymes concentration between infected and non-infected groups.  A significant increase in anti-inflammatory interleukin 10 level and a significant decrease in pro-inflammatory IL17, IL4, and IFN-γ were noticed in the infected dogs. Conclusion: It is concluded that dirofilariasis infection is considered to be a serious life-threatening disease for dogs in Iraq. Therefore, a periodic test for heartworm infection every six months is recommended to eradicate heartworm infestations. The infected animals must be treated according to the American Heartworm Association recommendations

Use of in vitro human keratinocyte models to study the effect of cooling on chemotherapy drug-induced cytotoxicity

A highly distressing side-effect of cancer chemotherapy is chemotherapy-induced alopecia (CIA). Scalp cooling remains the only treatment for CIA, yet there is no experimental evidence to support the cytoprotective capacity of cooling. We have established a series of in vitro models for the culture of human keratinocytes under conditions where they adopt a basal, highly-proliferative phenotype thus resembling the rapidly-dividing sub-population of native hair-matrix keratinocytes. Using a panel of chemotherapy drugs routinely used clinically (docetaxel, doxorubicin and the active metabolite of cyclophosphamide 4-OH-CP), we demonstrate that although these drugs are highly-cytotoxic, cooling can markedly reduce or completely inhibit drug cytotoxicity, in agreement with clinical observations. By contrast, we show that cytotoxicity caused by specific combinatorial drug treatments cannot be adequately attenuated by cooling, supporting data showing that such treatments do not always respond well to cooling clinically. Importantly, we provide evidence that the choice of temperature may be critical in determining the efficacy of cooling in rescuing cells from drug-mediated toxicity. Therefore, despite their reductive nature, these in vitro models have provided experimental evidence for the clinically-reported cytoprotective role of cooling and represent useful tools for future studies on the molecular mechanisms of cooling-mediated cytoprotection