Food impaction in older age: Think about an eosinophilic esophagitis

Eosinophilic esophagitis is an inflammatory condition of esophagus. It is generally seen in childhood and young population. Men are more commonly affected than women. However, it is not common in an advanced age. Eosinophilic esophagitis decreases the ability of the esophagus to stretch and accommodation against foods. Therefore, the major symptom in adults with eosinophilic esophagitis is difficulty in swallowing solid food (dysphagia). Specifically, the food gets stuck in the esophagus after it is swallowed. Less common symptoms include heartburn and chest pain. Because of this, it may be incorrectly diagnosed as a gastroesophageal reflux disease. Here, we reported a case presented with food impaction at advanced age. As a conclusion, eosinophilic esophagitis is a rare entity that must be remembered in advance aged patients presenting with food impaction

Advances in Rootstock Breeding of Nut Trees: Objectives and Strategies

The production and consumption of nuts are increasing in the world due to strong economic returns and the nutritional value of their products. With the increasing role and importance given to nuts (i.e., walnuts, hazelnut, pistachio, pecan, almond) in a balanced and healthy diet and their benefits to human health, breeding of the nuts species has also been stepped up. Most recent fruit breeding programs have focused on scion genetic improvement. However, the use of locally adapted grafted rootstocks also enhanced the productivity and quality of tree fruit crops. Grafting is an ancient horticultural practice used in nut crops to manipulate scion phenotype and productivity and overcome biotic and abiotic stresses. There are complex rootstock breeding objectives and physiological and molecular aspects of rootstock–scion interactions in nut crops. In this review, we provide an overview of these, considering the mechanisms involved in nutrient and water uptake, regulation of phytohormones, and rootstock influences on the scion molecular processes, including long-distance gene silencing and trans-grafting. Understanding the mechanisms resulting from rootstock × scion × environmental interactions will contribute to developing new rootstocks with resilience in the face of climate change, but also of the multitude of diseases and pests.info:eu-repo/semantics/publishedVersio

Gastroesophageal reflux in asymptomatic obese subjects: An esophageal impedance-pH study

Baran, Bulent/0000-0001-7966-2346; Uyanikoglu, Ahmet/0000-0003-4881-5244WOS: 000350689100021PubMed: 25780302AIM: To investigate the relationship between reflux and body mass index (BMI) in the asymptomatic obese population using the impedance-pH technique. METHODS: Gastroesophageal reflux is frequent in the obese population. However, the relationship between acid reflux and BMI in asymptomatic obese people is unclear. Forty-six obese (BMI > 25 kg/m(2)) people were enrolled in this prospective study. We evaluated the demographic findings and 24-h impedance pH values of the whole group. Gas, acid (pH 30 kg/m(2)). Demographic and endoscopic findings, and impedance results were similar in these two groups. However, there was a positive correlation between BMI and total and supine pH < 4 episodes (P = 0.002, r = 0.414; P = 0.000, r = 0.542), pH < 4 reflux time (P = 0.015, r = 0.319; P = 0.003, r = 0.403), and DeMeester score (P = 0.012, r = 0.333). CONCLUSION: Acid reflux is correlated with BMI in asymptomatic obese individuals

Food impaction in older age: Think about an eosinophilic esophagitis

Eozinofilik özofajit özofagusun inşamatuvar hastalığıdır. Genellikle genç erişkin yaşta görülür. İleri yaşta nadiren görülmektedir. Eozinofilik özofajit, özofagusun yiyeceklere karşı esnemesini ve uyumunu azaltır. Bu nedenle esas semptom disfajidir. Özellikle gıdaların takılmasına neden olur. Bu yazıda, ileri yaşta gıda takılması ile gelen bir vaka sunduk. Özet olarak, ileri yaşta gıda takılması ile başvuran hastalarda nadir olmasına karşın eozinofilik özofajit akılda tutulmalıdır.Eosinophilic esophagitis is an inflammatory disease of esophagus. It is generally seen in childhood and young population. It is not common in advanced age. Eosinophilic esophagitis decreases the ability of the esophagus to stretch and accommodation against foods. Therefore, the major symptom in adults with eosinophilic esophagitis is difficulty in swallowing solid food (dysphagia). Therefore, food stuck in the esophageal lumen is the specific manifestation when swallowing. He- rein, we reported a patient in old age presented with food impaction. In conclusion, eosinophilic esophagitis is a rare entity that must be considered in elderly patients complaining food impaction

The Effect of Night-Shift Work on Right Heart Function in Medical Employees

Introduction: In this study, we aimed to explore the effect of sleeplessness on right heart function in medical employees who have night-shift work. Patients and Methods: Fifty-two employees who work nightshifts were included in this study. Right ventricle tissue Doppler imaging (TDI), myocardial performance index (MPI), tricuspid annular plane systolic excursion (TAPSE) and pulmonary artery stiffness (PAS) were calculated using maximal frequency shift (MFS) and acceleration time (AcT) in addition to routine echocardiographic examination of all individuals. Results: When comparing right ventricular functions before and after a night shift, there was reduction of tricuspid E wave velocity after sleeplessness was determined (p<0.001); however no differences were observed in A wave velocity, tricuspid E/A ratio and right ventricle TDI parameters (tricuspid annulus E’, A’ and S’). A systolic function indicator TAPSE showed significant reduction after sleeplessness (25.71±3.05 before nightshift, 24.50±2.86 after nightshift; p<0.001). No significant differences in the right ventricle myocardial performance index (MPI; also known as the Tei Index) and pulmonary artery stiffness values were observed (MPI 0.47±0.17 before nightshift, 0.51±0.18 after nightshift; p=0.201 and PAS 25±15 before nightshift, 22±7, after nightshift; p=0.194, respectively). Conclusion: Sleeplessness caused reduction of TAPSE, one of the right ventricle systolic function indicators in medical employees. More comprehensive studies are required to determine the effects of sleeplessness on right heart function

What is the impact of capsule endoscopy in the long term period?

WOS: 000373288400004PubMed ID: 27076873AIM: To assess the clinical impact of capsule endoscopy (CE) in the long-term follow-up period in patients with obscure gastrointestinal bleeding (OGIB). METHODS: One hundred and forty-one patients who applied CE for OGIB between 2009 and 2012 were retrospectively analyzed, and this cohort was then questioned prospectively. Demographic data of the patients were determined via the presence of comorbid diseases, use of non-steroidal anti-inflammatory drugs anticoagulant-antiaggregant agents, previous diagnostic tests for bleeding episodes, CE findings, laboratory tests and outcomes. RESULTS: CE was performed on 141 patients because of OGIB. The capsule was retained in the upper gastrointestinal (GI) system in two of the patients, thus video monitoring was not achieved. There were 139 patients [62% male, median age: 72 years (range: 13-93 years) and a median follow-up duration: 32 mo (range: 6-82 mo)]. The overall diagnostic yield of CE was 84.9%. Rebleeding was determined in 40.3% (56/139) of the patients. The rebleeding rates of patients with positive and negative capsule results at the end of the follow-up were 46.6% (55/118) and 4.8% (1/21), respectively. In the multivariate analysis, usage of NSAIDs, anticoagulant-antiaggregant therapies (OR = 5.8; 95% CI: 1.86-18.27) and vascular ectasia (OR = 6.02; 95% CI: 2.568-14.146) in CE were detected as independent predictors of rebleeding. In the univariate analysis, advanced age, comorbidity, and overt bleeding were detected as predictors of rebleeding. CONCLUSION: CE is a reliable method in the diagnosis of obscure GI bleeding. Negative CE correlated with a significantly lower rebleeding risk in the long-term follow-up period