Respiratory Evolution Facilitated the Origin of Pterosaur Flight and Aerial Gigantism

Pterosaurs, enigmatic extinct Mesozoic reptiles, were the first vertebrates to achieve true flapping flight. Various lines of evidence provide strong support for highly efficient wing design, control, and flight capabilities. However, little is known of the pulmonary system that powered flight in pterosaurs. We investigated the structure and function of the pterosaurian breathing apparatus through a broad scale comparative study of respiratory structure and function in living and extinct archosaurs, using computer-assisted tomographic (CT) scanning of pterosaur and bird skeletal remains, cineradiographic (X-ray film) studies of the skeletal breathing pump in extant birds and alligators, and study of skeletal structure in historic fossil specimens. In this report we present various lines of skeletal evidence that indicate that pterosaurs had a highly effective flow-through respiratory system, capable of sustaining powered flight, predating the appearance of an analogous breathing system in birds by approximately seventy million years. Convergent evolution of gigantism in several Cretaceous pterosaur lineages was made possible through body density reduction by expansion of the pulmonary air sac system throughout the trunk and the distal limb girdle skeleton, highlighting the importance of respiratory adaptations in pterosaur evolution, and the dramatic effect of the release of physical constraints on morphological diversification and evolutionary radiation

Restoring youth justice New directions in domestic and international law and practice

SIGLEAvailable from British Library Document Supply Centre-DSC:m00/19577 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

Public defenders Learning from the US experience

SIGLEAvailable from British Library Document Supply Centre-DSC:m01/28706 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

Cancer in the thyroid is not always thyroid cancer

<p>Most clinicians assume that a thyroid mass which appears to be malignant is most likely a tumour arising from thyroid cells. We present a case where the thyroid malignancy was associated with a degree of systemic clinical and biochemical disturbance which suggested alternative diagnoses, and in which fine-needle aspiration revealed that the patient had a thyroid lymphoma. Gastric biopsy showed that this was a primary gastric diffuse B cell lymphoma. Subsequent management provided a number of challenging and overlapping problems, and the patient eventually died from this high-grade malignancy. We review the prevalence, presentation, diagnosis and management of lymphomas presenting as thyroid masses, and underline the problems in management when there is multi-system disease.</p

Integrating fish into irrigation infrastructure projects in Myanmar: rice-fish what if…?

With rapidly increasing investment in water control infrastructure (WCI) and a recently ratified agriculture development strategy that promotes integrated farming of high-value products such as fish, agricultural production, already fundamental to Myanmar’s economy, will be central to driving the countries’ socioeconomic transformation. Water planners and managers have a unique opportunity to design and manage WCI to incorporate fish and, in so doing, reduce conflicts and optimise the benefits to both people and the ecosystem services upon which they depend. Results from rice–fish culture experimental trials in Myanmar’s Ayeyarwady Delta are providing an evidence base for the importance of integrating fish into WCI, highlighting a range of both environmental and social benefits. By using less than 13% of paddy land area and through best management practices, existing rice productivity is sustained, alongside a 25% increase in economic returns for the same land area from fish. In addition, there are considerably more protein and micronutrients available from the fish produced in the system. Should these farming system innovations be adopted at scale, Myanmar stands to benefit from increased employment, incomes and nutritional value of farm plots (alongside associated reductions in pesticide pollution) and water use benefits