251 research outputs found
Gauge Thresholds and Kaehler Metrics for Rigid Intersecting D-brane Models
The gauge threshold corrections for globally consistent Z2 x Z2' orientifolds
with rigid intersecting D6-branes are computed. The one-loop corrections to the
holomorphic gauge kinetic function are extracted and the Kaehler metrics for
the charged chiral multiplets are determined up to two constants.Comment: 22 pages, 1 figure; v2: minor modifications, version to appear in
JHE
Formation and characterization of FeLV iscoms.
Immunostimulating complexes (ISCOMs) have been prepared from feline leukaemia virus (FeLV) envelope proteins. The ISCOMs were characterized biochemically in SDS-polyacrylamide gel electrophoresis showing the presence of proteins of estimated molecular weights of 15,000, 27,000 and 70,000. Immunoblotting showed that both the transmembrane protein p15E and the external glycoprotein gp70 (making up the gp85 protein) were present in the ISCOM. Furthermore, a degradation product of gp70 with an estimated molecular weight of 32,000 was identified in the immunoblot. The FeLV ISCOM was shown by electron microscopy to have the characteristic cage-like structure of an ISCOM with a mean diameter of 37 nm. About 10% of the total amount of gp70 in the culture fluid was recovered in the ISCOMs. The largest loss was encountered during the sedimentation of the virus. In a preliminary immunization experiment in mice the FeLV ISCOMs elicited after a booster gave a clear-cut immune response against gp70
Stringy Instantons and Cascading Quivers
D-brane instantons can perturb the quantum field theories on space-time
filling D-branes by interesting operators. In some cases, these D-brane
instantons are novel "stringy" effects (not interpretable directly as instanton
effects in the low-energy quantum field theory), while in others the D-brane
instantons can be directly interpreted as field theory effects. In this note,
we describe a situation where both perspectives are available, by studying
stringy instantons in quivers which arise at simple Calabi-Yau singularities.
We show that a stringy instanton which wraps an unoccupied node of the quiver,
and gives rise to a non-perturbative mass in the space-time field theory, can
be reinterpreted as a conventional gauge theory effect by going up in an
appropriate renormalization group cascade. Interestingly, in the cascade, the
contribution of the stringy instanton does not come from gauge theory
instantons but from strong coupling dynamics.Comment: 17 pages, 6 figures, harvma
âDetection and significance of adenoviruses in cases of sudden infant deathâ.
Respiratory tract infections have been thought to act as a trigger mechanism in sudden infant death. In 118 autopsy cases of infant death, paraffin-embedded or frozen lung tissues were investigated by means of a nested polymerase chain reaction (PCR) to detect adenovirus (AV) DNA. The primers used are general primers and allow the detection of most pathogenic adenoviruses with high specificity and sensitivity and independently of devitalization of viruses or degradation of viral DNA. For the investigation three groups were established: there were 13 cases of unnatural death, 78 cases of natural death without histological signs of interstitial pneumonia, and 27 cases with interstitial pneumonia. The first group was AV negative. In the group without interstitial pneumonia AV was detected in 10.2% of the cases. In the group with interstitial pneumonia the frequency of AV detection was almost 26%. The results obtained demonstrate an association between interstitial pneumonia and detection of AV DNA, indicating that AV may play an important part in pulmonary infection in infants. Histological evidence of interstitial pneumonia was not observed in all AV-positive cases, perhaps because nonspecific virus-related changes occurred only in early stages of viral infection. Comparison of the AV frequency in SIDS (15%) and non-SIDS cases (4%) indicates an association between pulmonary AV infections and sudden death. These results support the working hypothesis of respiratory infections acting as a trigger mechanism in sudden infant death
Comparative study of elemental mercury flux measurement techniques over a Fennoscandian boreal peatland
Quantitative estimates of the land-atmosphere exchange of gaseous elemental mercury (GEM) are biased by the measurement technique employed, because no standard method or scale in space and time are agreed upon. Here we present concurrent GEM exchange measurements over a boreal peatland using a novel relaxed eddy accumulation (REA) system, a rectangular Teflon (R) dynamic flux chamber (DFC) and a DFC designed according to aerodynamic considerations (Aero-DFC). During four consecutive days the DFCs were placed alternately on two measurement plots in every cardinal direction around the REA sampling mast. Spatial heterogeneity in peat surface characteristics (0-34 cm) was identified by measuring total mercury in eight peat cores (57 +/- 8 ng g(-1), average SE), vascular plant coverage (32-52%), water table level (4.5-14.1 cm) and dissolved gaseous elemental mercury concentrations (28-51 pg L-1) in the peat water. The GEM fluxes measured by the DFCs showed a distinct diel pattern, but no spatial difference in the average fluxes was detected (ANOVA, alpha = 0.05). Even though the correlation between the Teflon DFC and Aero-DFC was significant (r = 0.76, p < 0.05) the cumulative flux of the Aero-DFC was a factor of three larger. The average flux of the Aero-DFC (1.9 ng m(-2) h(-1)) and REA (2 ng m(-2) h(-1)) were in good agreement. The results indicate that the novel REA design is in agreement for cumulative flux estimates with the Aero-DFC, which incorporates the effect of atmospheric turbulence. The comparison was performed over a fetch with spatially rather homogenous GEM flux dynamics under fairly consistent weather conditions, minimizing the effect of weather influence on the data from the three measurement systems. However, in complex biomes with heterogeneous surface characteristics where there can be large spatial variability in GEM gas exchange, the small footprint of chambers ( < 0.2 m(2)) makes for large coefficients of variation. Thus many chamber measurement replications are needed to establish a credible biome GEM flux estimate, even for a single point in time. Dynamic flux chambers will, however, be able to resolve systematic differences between small scale features, such as experimentally manipulated plots or small scale spatial heterogeneity
Unoriented D-brane Instantons vs Heterotic worldsheet Instantons
We discuss Fermi interactions of four hyperini generated by ``stringy''
instantons in a Type I / Heterotic dual pair on T^4/Z_2.Comment: Minor corrections and clarifications. Added reference
Lifting D-Instanton Zero Modes by Recombination and Background Fluxes
We study the conditions under which D-brane instantons in Type II orientifold
compactifications generate a non-perturbative superpotential. If the instanton
is non-invariant under the orientifold action, it carries four instead of the
two Goldstone fermions required for superpotential contributions. Unless these
are lifted, the instanton can at best generate higher fermionic F-terms of
Beasley-Witten type. We analyse two strategies to lift the additional zero
modes. First we discuss the process of instantonic brane recombination in Type
IIA orientifolds. We show that in some cases charge invariance of the measure
enforces the presence of further zero modes which, unlike the Goldstinos,
cannot be absorbed. In other cases, the instanton exhibits reparameterisation
zero modes after recombination and a superpotential is generated if these are
lifted by suitable closed or open string couplings. In the second part of the
paper we address lifting the extra Goldstinos of D3-brane instantons by
supersymmetric three-form background fluxes in Type IIB orientifolds. This
requires non-trivial gauge flux on the instanton. Only if the part of the
fermionic action linear in the gauge flux survives the orientifold projection
can the extra Goldstinos be lifted.Comment: 38 pages, 3 figures, 5 tables; v2: Appendix B slightly expanded,
minor rewordin
D-instanton derivation of multi-fermion F-terms in supersymmetric QCD
We investigate effects of field theory instantons by considering D-instantons
in a suitable D3-brane background. In supersymmetric QCD with SU(N_c) gauge
group with N_f=N_c flavors, the moduli space of vacua is deformed by
instantons. This effect can be described by the chiral interactions which are
called multi-fermion F-terms. We derive these chiral interaction terms as
D-instanton effects in the presence of D3-branes. For SU(2), the obtained
result agrees with the previous result worked out by Beasley and Witten
[hep-th/0409149]. We also explicitly work out those for the case of the
symplectic gauge group, and show that they describe the deformation of the
moduli space.Comment: 25 page
Dynamical supersymmetry breaking from unoriented D-brane instantons
We study the non-perturbative dynamics of an unoriented Z_5-quiver theory of
GUT kind with gauge group U(5) and chiral matter. At strong coupling the
non-perturbative dynamics is described in terms of set of baryon/meson
variables satisfying a quantum deformed constraint. We compute the effective
superpotential of the theory and show that it admits a line of supersymmetric
vacua and a phase where supersymmetry is dynamically broken via gaugino
condensation.Comment: 24 pages, 1 figur
Instanton Induced Neutrino Majorana Masses in CFT Orientifolds with MSSM-like spectra
Recently it has been shown that string instanton effects may give rise to
neutrino Majorana masses in certain classes of semi-realistic string
compactifications. In this paper we make a systematic search for supersymmetric
MSSM-like Type II Gepner orientifold constructions admitting boundary states
associated with instantons giving rise to neutrino Majorana masses and other L-
and/or B-violating operators. We analyze the zero mode structure of D-brane
instantons on general type II orientifold compactifications, and show that only
instantons with O(1) symmetry can have just the two zero modes required to
contribute to the 4d superpotential. We however discuss how the addition of
fluxes and/or possible non-perturbative extensions of the orientifold
compactifications would allow also instantons with and U(1) symmetries
to generate such superpotentials. In the context of Gepner orientifolds with
MSSM-like spectra, we find no models with O(1) instantons with just the
required zero modes to generate a neutrino mass superpotential. On the other
hand we find a number of models in one particular orientifold of the Gepner
model with instantons with a few extra uncharged
non-chiral zero modes which could be easily lifted by the mentioned effects. A
few more orientifold examples are also found under less stringent constraints
on the zero modes. This class of instantons have the interesting
property that R-parity conservation is automatic and the flavour structure of
the neutrino Majorana mass matrices has a simple factorized form.Comment: 68 pages, 2 figures; v2. typos corrected, refs adde
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