Sharps Injury Prevention for Hospital Workers

Objectives. The purpose of this study was to collect data on self-reported sharps injuries to develop best practices to reduce them. Methods. Data on sharps injuries were collected for the period of January–October 2008 using Adverse Event Notification Forms already in use at Sema Hospital. Results. On average, 0.2% of all self-reported injuries were sharps injuries averaging one injury per month. Housekeeping staff sustained 64% of such injuries, nurses sustained 36% (5 incidents). Outpatient clinics experienced the most injuries at 28%, followed by the Internal Diseases Inpatient Unit with 21% and the Medical Waste Room with 14%. Injuries often occurred during contact with medical waste bags (28%) and while replacing full sharp-boxes (14%). Conclusion. In summary, reducing needle stick injuries is an important component of the occupational and patient safety program at Sema Hospital. The research described in this study allowed the hospital to provide targeted interventions to increase awareness of the risks of needle stick injuries and reduce such injuries. The steps used in the study can be used in any health care organization in the world to design a customized improvement plan to reduce risk and injury

Co-infection relationship with Epstein-Barr virus in gastroduodenal diseases with Helicobacter Pylori. Quantitative PCR and EBNA-1 gene-based approach

Objective: Helicobacter pylori (Hp) and Epstein-Barr virus (EBV) are involved in gastric cancer (GC) etiology. EBV/Hp co infection was thought synergistically increase gastroduodenal disease occurence. We aimed to determine the presence of EBV/Hp co-infection in gastroduodenal diseases. Methods: The study group had 68 Hp (+) cases [25 GC, 13 IM (intestinal metaplasia), 30 PU (peptic ulcer)], and the control group had 40 NUD (non-ulcer dyspepsia) cases [20 Hp+, 20 Hp-]. EBV-DNA was detected by non-polymorphic EBNA-1 gene-based qPCR. EBV/EBNA-1 IgG levels were determined by quantitative and qualitative ELISA methods, respectively. Results: EBV-DNA positivity was 32% (8/25), 6.6% (2/30) and 5% (1/20) in GC, PU and NUD Hp (+) cases, respectively. There was a significant difference (p = 0.001) between GC (32%) and NUD Hp (+) (5%) cases in terms of EBV-DNA positivity. Mean EBV-DNA copy numbers were 6568.54 ?? 20351, 30.60 ?? 159.88 and 13.85 ?? 61.93 for GC, PU, and NUD, respectively. In terms of the mean EBV-DNA copy number, a significant difference was found between the groups (p = 0.005). In terms of EBV/EBNA-1 IgG antibody positivity, no significant difference was found between GC and NUD cases (p = 0.248). EBV DNA positivity was found to be significant (odds ration [OR] = 26.71 (p=0.009, %95CI 2.286312.041) in multivariate logistic regression. Conclusio??n: Although we had a small number of GC cases, it can be suggested that the estimated risk created by the synergistic effect based on the addition of EBV increased 26 times in the presence of Hp in GC. (Acta gastroenterol. belg., 2022, 85, 301-308)

USING PARTICLE SWARM OPTIMIZATION TO ESTABLISH A LOCAL GEOMETRIC GEOID MODEL

There exist a number of methods for approximating the local geoid surface and studies carried out to determine a local geoid. In this study, performance of geoid by PSO method in modeling local geoid was presented and analyzed. The ellipsoidal heights (h), derived from GPS observations, and known orthometric heights from first-order bench marks were first used to create local geometric geoid model, then the PSO method was used to convert ellipsoidal heights into orthometric heights (H). The resulting values were used to compare between the spirit leveling and GPS methods. The adopted PSO method can improve the fitting of local geometric geoid by quadratic surface fitting method, which agrees with the known orthometric heights within ±1.02cmthe Cartography produced: General Map, Partial Maps, Profile, Cross Sections and others

Antidiabetic potential and multi-biological activities of Trachystemon orientalis extracts

yalcin, emine/0000-0002-5280-5375WOS: 000493661900039Due to the increase in exposure to chemical substances, the investigation of natural compounds with protective effects has become popular. So in this study the antimicrobial, antioxidant, antimutagenic activities and enzyme inhibitory effects of Trachystemon orientalis leaf and stem extracts were investigated. Antimicrobial effect was determined by disc diffusion method and the antimutagenic effect was investigated by Ames/Salmonella/microsomal test. Antioxidant properties of T. orientalis extracts were determined by investigating the phytochemical contents and 2,2-diphenyl-1-picrylhydrazyl (DPPH) removal activity. The antidiabetic activity of the extracts was investigated by alpha-amylase and alpha-glucosidase enzyme inhibition. It has been determined that all extracts exhibit antimicrobial activity at different ratios and the highest antimicrobial activity was obtained with a 21 +/- 0.4 mm inhibition zone against Escherichia coli. The highest DPPH removal activity of leaf and stem extracts was determined to be 65.1 +/- 2.4% and 59.4 +/- 2.7%, respectively. In enzyme inhibitory analysis, it was determined that the alpha-glucosidase inhibitory effect of extracts was higher than the alpha-amylase inhibition effect. In antimutagenity test, the highest antimutagenic effects of leaf and stem extract were determined as 78.2 +/- 1.1% and 67.2 +/- 1.5%, respectively. As a result, T. orientalis leaf and stem extracts were determined as a potential natural antimicrobial, antimutagenic and antioxidant source with a moderately high antidiabetic activity