Haematic Potentials of Rhynchospora Corymbosa and Olax Subscorpioïdea Extract in Phenylhydrazine – induced Anaemic Rats

The decoction of the whole plant of Rhynchospora corymbosa and Olax subscorpioïdea leaves are used by the Local traditional healers in the department of Korhogo (Northern Côte d’Ivoire) to treat patients with sickle cell disease. This study was designed to assess, the antianemic potential of these plants extract. Anemia was induced with phenylhydrazine hydrochloride in rats. Animals were divided in normal (N), control (C), test (T), and reference (R) groups. T group included ill-induced Animals treated with R. corymbosa and O. subscorpioidea extracts, and R group ill-induced animals treated with vitamin B9 for anemic animals. Dosing was made as 1-day single dose repeated dose. In anemic animals, the production rate of RBC was significantly (p < 0.001) higher in T group as compared to C group. R. corymbosa whole plant and O. subscorpioidea leaves extracts have a haematic potential. The anti-anaemic effect may partly explain their use in patients with sickle cell disease who are affected by a deficiency of erythrocytes and its components

COVID-19 autopsy reports from the Ga-East Municipal and the 37 Military Hospitals in Accra, Ghana

Introduction: Since the declaration of COVID-19 by the World Health Organisation (WHO) as a global pandemic on 11th March 2020, the number of deaths continue to increase worldwide. Reports on its pathologic manifestations have been published with very few from the Sub-Saharan African region. This article reports autopsies on COVID-19 patients from the Ga-East and the 37 Military Hospitals to provide pathological evidence for better understanding of COVID-19 in Ghana.Methods: Under conditions required for carrying out autopsies on bodies infected with category three infectious agents, with few modifications, complete autopsies were performed on twenty patients with ante-mortem and/or postmortem RT -PCR confirmed positive COVID‑19 results, between April and June ,2020.Results: There were equal proportion of males and females. Thirteen (65%) of the patients were 55years or older with the same percentage (65%) having Type II diabetes and/or hypertension. The most significant pathological feature found at autopsy was diffuse alveolar damage. Seventy per cent (14/20) had associated thromboemboli in the lungs, kidneys and the heart. Forty per cent (6/15) of the patients that had negative results for COVID-19 by the nasopharyngeal swab test before death had positive results during postmortem using bronchopulmonary specimen. At autopsy all patients were identified to have pre-existing medical conditions.Conclusion: Diffuse alveolar damage was a key pathological feature of deaths caused by COVID-19 in all cases studied with hypertension and diabetes mellitus being major risk factors. Individuals without co-morbidities were less likely to die or suffer severe disease from SARS-CoV-

Haematic Potentials of Rhyhchospora corymbosa and Olax subscorpioïdea Extracti in Phenylhydrazine-induced Anaemic Rats

The decoction of the whole plant of Rhynchospora corymbosa and Olax subscorpioïdea leaves are used by the Local traditional healers in the department of Korhogo (Northern Côte d’Ivoire) to treat patients with sickle cell disease. This study was designed to assess, the antianemic potential of these plants extract. Anemia was induced with phenylhydrazine hydrochloride in rats. Animals were divided in normal (N), control (C), test (T), and reference (R) groups. T group included ill-induced Animals treated with R. corymbosa and O. subscorpioidea extracts, and R group ill-induced animals treated with vitamin B9 for anemic animals. Dosing was made as 1-day single dose repeated dose. In anemic animals, the production rate of RBC was significantly (p < 0.001) higher in T group as compared to C group. R. corymbosa whole plant and O. subscorpioidea leaves extracts have a haematic potential. The anti-anaemic effect may partly explain their use in patients with sickle cell disease who are affected by a deficiency of erythrocytes and its components

Haematic Potentials of Rhynchospora Corymbosa and Olax Subscorpioïdea Extract in Phenylhydrazine – induced Anaemic Rats

The decoction of the whole plant of Rhynchospora corymbosa and Olax subscorpioïdea leaves are used by the Local traditional healers in the department of Korhogo (Northern Côte d’Ivoire) to treat patients with sickle cell disease. This study was designed to assess, the antianemic potential of these plants extract. Anemia was induced with phenylhydrazine hydrochloride in rats. Animals were divided in normal (N), control (C), test (T), and reference (R) groups. T group included ill-induced Animals treated with R. corymbosa and O. subscorpioidea extracts, and R group ill-induced animals treated with vitamin B9 for anemic animals. Dosing was made as 1-day single dose repeated dose. In anemic animals, the production rate of RBC was significantly (p < 0.001) higher in T group as compared to C group. R. corymbosa whole plant and O. subscorpioidea leaves extracts have a haematic potential. The anti-anaemic effect may partly explain their use in patients with sickle cell disease who are affected by a deficiency of erythrocytes and its components

Haematic Potentials of Rhyhchospora corymbosa and Olax subscorpioïdea Extracti in Phenylhydrazine-induced Anaemic Rats

The decoction of the whole plant of Rhynchospora corymbosa and Olax subscorpioïdea leaves are used by the Local traditional healers in the department of Korhogo (Northern Côte d’Ivoire) to treat patients with sickle cell disease. This study was designed to assess, the antianemic potential of these plants extract. Anemia was induced with phenylhydrazine hydrochloride in rats. Animals were divided in normal (N), control (C), test (T), and reference (R) groups. T group included ill-induced Animals treated with R. corymbosa and O. subscorpioidea extracts, and R group ill-induced animals treated with vitamin B9 for anemic animals. Dosing was made as 1-day single dose repeated dose. In anemic animals, the production rate of RBC was significantly (p < 0.001) higher in T group as compared to C group. R. corymbosa whole plant and O. subscorpioidea leaves extracts have a haematic potential. The anti-anaemic effect may partly explain their use in patients with sickle cell disease who are affected by a deficiency of erythrocytes and its components

The use of biopesticides to control insect pests of papaya (Carica papaya)

Laboratory and field experiments were carried out between June 1997 and January 1999 at Paradise farm near Nsawam in the Eastern Region of Ghana to evaluate the effectiveness of neem seed extract and Bacillus thuringiensis (Kurtaski) for controlling insect pests of papaya Carica papaya. Methanol and aqueous neem seed extracts were tested at the following concentrations 0, 50, 75 and 100 g/L. Bacillus thuringiensis was applied at the rate of 0, 0.2, 0.4, 0.6, 0.8 and 1.0 g/L. Percentage mortality and leaf damage caused by insect pests were determined in the laboratory and in the field. The population of the major insect pests, which visited the plants, was also determined. The nature of the damage caused by the insect pests found on the various developmental stages of the plants was assessed by critical visual observation. The major insect pests recorded on papaya at Paradise farm were the variegated grasshopper, Zonocerus variegates (L), mealybugs, Planococcus sp and Mexican bean beetle, Epilachna sp. It was observed in the field that the populations of these insect pests were significantly reduced by the higher doses of methanol and aqueous neem extracts as well as the Bacillus thuringiensis treatments. The neem seed extracts and Bacillus thuringiensis preparations had significant effect on the mortality of adult and nymphs of Z. variegatus in the laboratory and in the field compared to the control. The rate of mortality increased as the dose increases. Hundred grams per litre of methanol and aqueous neem seed extract and 1 g of B. thuringiensis per litre of water were the most effective and induced the highest mortality of adults and nymphs of Z. variegatus compared to the other treatments. The least percentage leaf damage was recorded on papaya plants treated with the highest dosage of neem extract and B. thuringiensis. (Journal of the Ghana Science Association: 2001 3(3): 117-125