An Overview of Export and Import of Pulses in India

Pulses are an important part of Indian daily diets. Pulses are a key commodity category of crops that supply high quantity protein to the country's mainly vegetarian population, supplementary grains proteins. India is the world's leading producer and consumer of pulses. India imports a considerable number of pulses to meet the domestic requirement of pulses. India remains responsible for almost 15 percent of the import-export, 27 percent of the total consumption of pulses at the world level, and 25 percent of the total production of the pulses every year

Normative Study on Motor Fitness Test for University Boys

The purpose of the study was to construct a motor fitness test for identification and selection of talent at university level. Various test items were selected in the initial phase which was finally reduced to a four test item battery after scientific evaluation of the items selected. The study involved 258 college boys between the age group of 17-25years belonging to various colleges of Delhi NCR, India. Percentile norms were constructed for the evaluation of motor fitness level, which could be used as standard criteria for identification and selection of potential talent at the university level. Keywords: Motor fitness, physical fitness, motor abilities, university

Quality Assessment Of Andrographis Paniculata (Burm. F.) Wall. Ex Nees W.S.R To Geographical Region.

Kalmegh Andrographispaniculata (Burm. F.) Wall. Ex Nees is one of the main ingredients used in many formulations like Mahavishgarbhataila etc, India`s various part having favourable for Kalamegh plant, but geographical environmental influences the physico-chemical properties like Ash, extractives values and phytoconstituents. All samples passes ayurvedic Pharmacopeial standards but strength showed variations and Belgaum region showed best for Kalamegh . Thus, study revels that medicinal plants collection habitat must be considered

Ego: An Epistemological Analysis Of Self-Centric Consciousness

This Article probes into the profound intricacies of ego, a multifaceted paradigm of self-centric consciousness that has garnered significant scholarly interest across various disciplines. By drawing on philosophical and psychological theories, this rigorous exploration aims to elucidate the nuanced dimensions of ego, shedding light on its ontological essence and intricate interaction within the human psyche. Additionally, this article explores how the cultural context influences the conceptualization and experience of ego in Eastern philosophies, such as Hinduism and Buddhism, in comparison to Western philosophical and psychological frameworks. By undertaking a comparative analysis, this research seeks to uncover the cultural variations in understanding ego, encompassing diverse perspectives on self-identity, interconnectedness, and the role of ego within these distinct traditions. By examining the influence of cultural context, this investigation contributes to a deeper comprehension of the cultural contingency of ego, ultimately enriching our understanding of this fundamental construct in the broader landscape of human consciousness and subjective experience

A Review on Grid Integration Challenges of Wind Energy Systems

In recent decades, the strengthening of electric energy security and the reduction of greenhouse gas emissions acquired great traction. The integration of large-scale intermittent renewable energy resources (RER) such as wind energy into existing electrical systems has risen dramatically in recent years. In the last few years, however, this integration creates several operational and control issues that impede the process. Grid functioning must be reliable and stable. This article will look at the problems that have been documented as a result of the recommended solutions techniques and the integration of wind energy Among the many difficulties, Generation uncertainty, power quality difficulties, angular and voltage stability, and reactive power support are all factors to consider. The ability to ride through faults is examined and explored. Aside from that, there are financial, environmental, and political factors to consider

Mood stabilizers in pregnancy and lactation

Abstract Management of bipolar during pregnancy and postpartum is very challenging. The treating clinicians have to take into account various factors like current mental state, longitudinal history of the patient, past history of relapse while off medication, response to medication, time of pregnancy at which patient presents to the clinician, etc. The choice of drug should depend on the balance between safety and efficacy profile. Whenever patient is on psychotropic medication, close and intensive monitoring should be done. Among the various mood stabilizers, use of lithium during the second and third trimester appears to be safe. Use of valproate during first trimester is associated with major malformation and long-term sequalae in the form of developmental delay, lower intelligence quotient, and higher risk of development of autism spectrum disorder. Similarly use of carbamazepine in first trimester is associated with higher risk of major congenital malformation and its use in first trimester is contraindicated. Data for lamotrigine (LTG) appears to be more favorable than other antiepileptics. During lactation, use of valproate and LTG is reported to be safe. Use of typical and/atypical antipsychotic is a good option during pregnancy in women with bipolar disorder

REAL-TIME EEG BASED OBJECT RECOGNITION

A Brain Computer Interface (BCI) provides a communication path between human brain and the computer system. The major goal of BCI research is to develop a system that allows disabled people to communicate with other people, to control artificial limbs, or to control their environment. BCI is a challenging topic of computer vision research. It is extensively used by disabled people to communicate with other persons and helps to interact with the external environments. This paper provides an insight into object recognition by analyzing EEG signals in real-time. Three machine learning algorithms are implemented which are used for classification by supervised learning, namely Decision Trees, K-Nearest Neighbors and Support Vector Machine (SVM), multiple training sets and users are taken into account during the experiment and the efficiency of each algorithm is compared to suggest the best suited algorithm for this purpose

Viral non-coding RNA inhibits HNF4α expression in HCV associated hepatocellular carcinoma

BACKGROUND: Hepatitis C virus (HCV) infection is an established cause of chronic hepatitis, cirrhosis and hepatocellular carcinoma (HCC); however, it is unclear if the virus plays a direct role in the development of HCC. Hepatocyte nuclear factor 4α (HNF4α) is critical determinant of epithelial architecture and hepatic development; depletion of HNF4α is correlated with oncogenic transformation. We explored the viral role in the inhibition of HNF4α expression, and consequent induction of tumor-promoting genes in HCV infection-associated HCC. METHODS: Western blot analysis was used to monitor the changes in expression levels of oncogenic proteins in liver tissues from HCV-infected humanized mice. The mechanism of HNF4α depletion was studied in HCV-infected human hepatocyte cultures in vitro. Targeting of HNF4α expression by viral non-coding RNA was examined by inhibition of Luciferase HNF4α 3’-UTR reporter. Modulation of invasive properties of HCV-infected cells was examined by Matrigel cell migration assay. RESULTS: Results show inhibition of HNF4α expression by targeting of HNF4α 3’-UTR by HCV-derived small non-coding RNA, vmr11. Vmr11 enhances the invasive properties of HCV-infected cells. Loss of HNF4α in HCV-infected liver tumors of humanized mice correlates with the induction of epithelial to mesenchymal transition (EMT) genes. CONCLUSIONS: We show depletion of HNF4α in liver tumors of HCV-infected humanized mice by HCV derived small non-coding RNA (vmr11) and resultant induction of EMT genes, which are critical determinants of tumor progression. These results suggest a direct viral role in the development of hepatocellular carcinoma

Mycobacterium indicus pranii Supernatant Induces Apoptotic Cell Death in Mouse Peritoneal Macrophages In Vitro

Mycobacterium indicus pranii (MIP), also known as Mw, is a saprophytic, non-pathogenic strain of Mycobacterium and is commercially available as a heat-killed vaccine for leprosy and recently tuberculosis (TB) as part of MDT. In this study we provide evidence that cell-free supernatant collected from original MIP suspension induces rapid and enhanced apoptosis in mouse peritoneal macrophages in vitro. It is demonstrated that the MIP cell-free supernatant induced apoptosis is mitochondria-mediated and caspase independent and involves mitochondrial translocation of Bax and subsequent release of AIF and cytochrome c from the mitochondria. Experiments with pharmacological inhibitors suggest a possible role of PKC in mitochondria-mediated apoptosis of macrophages

Ultra-high resolution X-ray structures of two forms of human recombinant insulin at 100 K

The crystal structure of a commercially available form of human recombinant (HR) insulin, Insugen (I), used in the treatment of diabetes has been determined to 0.92 Å resolution using low temperature, 100 K, synchrotron X-ray data collected at 16,000 keV (λ = 0.77 Å). Refinement carried out with anisotropic displacement parameters, removal of main-chain stereochemical restraints, inclusion of H atoms in calculated positions, and 220 water molecules, converged to a final value of R = 0.1112 and Rfree = 0.1466. The structure includes what is thought to be an ordered propanol molecule (POL) only in chain D(4) and a solvated acetate molecule (ACT) coordinated to the Zn atom only in chain B(2). Possible origins and consequences of the propanol and acetate molecules are discussed. Three types of amino acid representation in the electron density are examined in detail: (i) sharp with very clearly resolved features; (ii) well resolved but clearly divided into two conformations which are well behaved in the refinement, both having high quality geometry; (iii) poor density and difficult or impossible to model. An example of type (ii) is observed for the intra-chain disulphide bridge in chain C(3) between Sγ6–Sγ11 which has two clear conformations with relative refined occupancies of 0.8 and 0.2, respectively. In contrast the corresponding S–S bridge in chain A(1) shows one clearly defined conformation. A molecular dynamics study has provided a rational explanation of this difference between chains A and C. More generally, differences in the electron density features between corresponding residues in chains A and C and chains B and D is a common observation in the Insugen (I) structure and these effects are discussed in detail. The crystal structure, also at 0.92 Å and 100 K, of a second commercially available form of human recombinant insulin, Intergen (II), deposited in the Protein Data Bank as 3W7Y which remains otherwise unpublished is compared here with the Insugen (I) structure. In the Intergen (II) structure there is no solvated propanol or acetate molecule. The electron density of Intergen (II), however, does also exhibit the three types of amino acid representations as in Insugen (I). These effects do not necessarily correspond between chains A and C or chains B and D in Intergen (II), or between corresponding residues in Insugen (I). The results of this comparison are reported