Effect of peppermint on pediatrics’ pain under endoscopic examination of the large bowel

Introduction: Colonoscopy is a painful and invasive technique for patients especially for pediatrics. Peppermint has analgesic effect. Therefore, we wish to look at the effect of peppermint essence on the patients&rsquo; satisfaction and pain after colonoscopy. Methods: This clinical trial study was performed on 100 patient&rsquo;s candidate for colonoscopy. Patients were randomly divided into two groups. Control group received no drug. Case group was administrated supermint essence thirty minutes before colonoscopy. A valid questionnaire was filled during the colonoscopy for patient&rsquo;s satisfaction and pain evaluation. Results: The mean value of abdominal pain was 0.527&plusmn;2.500 in control group and 1.625&plusmn;0.491 in case group after treatment (p&lt;0.05). Degree of satisfaction was 8 and 17.6 percent in control and case groups, respectively. Mean value of satisfaction in control group was 1.833&plusmn;0.389 that was significantly different from case group (2.607&plusmn;0.566) (p&lt;0.05). Duration of colonoscopy in control group was significantly higher than the one in case group (p&lt;0.05). Conclusion: Our findings showed that peppermint essence causes an increasing in satisfaction as well as a reduction in pain in patients under the colonoscopy.</p

The effect of supermint oral drop (peppermint essence) on the patients’ pain and their satisfaction after colonoscopy

زمینه و هدف: کولونوسکپی روشی تهاجمی است که برای بیمار به ویژه کودکان ناراحت کننده و دردناک است. هدف از تحقیق حاضر بررسی میزان تأثیر تجویز قطره خوراکی سوپرمینت (اسانس نعناع) بر درد و رضایتمندی بیمار پس از عمل کولونوسکوپی بوده است. روش بررسی: در این مطالعه کارآزمایی بالینی، 101 بیمار کاندید عمل کولونوسکوپی به روش در دسترس انتخاب و به طور تصادفی به دو گروه تقسیم شدند. به گروه شاهد(50 نفر) دارویی تجویز نشد. به گروه مورد (51 نفر)، 20 قطره خوراکی سوپرمینت 30 دقیقه قبل از کولونوسکوپی خورانده شد. پس از عمل کولونوسکوپی با استفاده از پرسشنامه استاندارد میزان درد و رضایتمندی بیمار بررسی شد. داده ها توسط آزمون توصیفی و تحلیلی (t-test) مورد تجزیه و تحلیل قرار گرفت. یافته ها: میانگین میزان دردهای شکمی در گروه شاهد 527/0±500/2 و در گروه مورد 491/0± 625/1 از نمره 10 بود (05/0

Isolation and genetic fingerprinting of Pseudomonas aeruginosa from Iranian patients with cystic fibrosis using RAPD-PCR

Abstract Sixty four Iranian patients with cystic fibrosis (CF) wer

Ganar o no ganar: cómo triunfar en la Liga de Campeones asiática

In professional sports, predicting success factors is very vital and important and is always questionable. The failure of teams in the leagues has been a constant issue and progress and gaining status has been a challenge for all clubs; and managers, officials, sports federations and clubs, and even researchers, are trying to shed light on the various dimensions of this issue. The purpose of this study was providing a model of predicting the success of football clubs in the Asian Champions League. The present study is descriptive-correlational. Seven Asian countries that won the Asian Champions League (ACL) were analyzed between 2014 and 2019. At the level of descriptive statistics, mean and standard deviation, and at the level of inferential statistics, because the response variable (success) was a qualitative variable, the logistic regression model was used. Data analysis was performed using SPSS software. Findings showed that 80% of the success of clubs in the ACL is correctly identified using the research model and foreign players, the average value of each player, the total value of the club and the number of players in a team have a positive impact on the success of football clubs. The age of the players has a negative effect, in other words, the lower average age can contribute to the success of football clubs. Therefore, these factors are considered as a comparative advantage for the success of clubs and managers and stakeholders are suggested to put the necessary planning and investment on their agenda to achieve these things.En los deportes profesionales, predecir los factores de éxito es muy vital e importante y siempre es cuestionable. El fracaso de los equipos en las ligas ha sido un tema constante y progresar y ganar estatus ha sido un reto para todos los clubes; y directivos, funcionarios, federaciones y clubes deportivos, e incluso investigadores, intentan arrojar luz sobre las diversas dimensiones de este problema. El propósito de este estudio fue proporcionar un modelo para predecir el éxito de los clubes de fútbol en la Liga de Campeones de Asia. El presente estudio es descriptivo-correlacional. Se analizaron siete países asiáticos que ganaron la Asian Champions League (ACL) entre 2014 y 2019. A nivel de estadística descriptiva, media y desviación estándar, y a nivel de estadística inferencial, porque la variable respuesta (éxito) fue una variable cualitativa. se utilizó el modelo de regresión logística. El análisis de datos se realizó con el software SPSS. Los hallazgos mostraron que el 80% del éxito de los clubes en la ACL se identifica correctamente utilizando el modelo de investigación y los jugadores extranjeros, el valor promedio de cada jugador, el valor total del club y la cantidad de jugadores en un equipo tienen un impacto positivo en El éxito de los clubes de fútbol. La edad de los jugadores tiene un efecto negativo, es decir, la menor edad media puede contribuir al éxito de los clubes de fútbol. Por lo tanto, estos factores se consideran una ventaja comparativa para el éxito de los clubes y se sugiere a los gerentes y partes interesadas que incluyan la planificación y la inversión necesarias en su agenda para lograr estas cosas.Actividad Física y Deport

Imunoproliferacijska bolest tankog crijeva manifestirana ascitesom i edemom

Immunoproliferative small intestinal disease (IPSID) is a rare disorder, which can progress to malignancy and invasion. Herein, a male patient is presented with hypoalbuminemic ascites and a history of chronic diarrhea five years before. Small intestinal biopsy and immunohistochemical study suggested the diagnosis of IPSID; the patient was then successfully treated with antibiotics. Considering the favorable therapeutic response of IPSID to antibiotics during primary stages, clinicians should be aware of its various presentations in order to initiate treatment at an early stage.Imunoproliferacijska bolest tankog crijeva je rijetka bolest koja može napredovati u malignu i invazivnu bolest. Prikazuje se slučaj bolesnika s hipoalbuminemičnim ascitesom i petogodišnjom anamnezom kroničnog proljeva. Biopsija tankog crijeva i imunohistokemijske pretrage upućivale su na dijagnozu imunoproliferacijske bolesti tankog crijeva, te je bolesnik uspješno liječen antibioticima. S obzirom na povoljan terapijski odgovor na antibiotike u ranim stadijima ove bolesti kliničari bi trebali poznavati njezine raznolike manifestacije kako bi pravodobno uveli primjerenu terapiju

The study of upper gastrointestinal endoscopy in patients with inflammatory bowel disease and ulcerative colitis

زمینه و هدف: در بررسی های تشخیصی بیماری های التهابی روده، یکی از موارد تشخیصی انجام آندوسکوپی فوقانی است که علاوه بر تأیید تشخیص، در افتراق کولیت های نامشخص نیز کمک کننده است. هدف از این مطالعه بررسی لزوم انجام آندوسکوپی فوقانی در بیماران مبتلا به التهاب روده بوده است. روش بررسی: در این مطالعه توصیفی- تحلیلی تعداد 30 کودک در بیمارستان مرکز طبی به صورت سرشماری از مهر 1388 تا اسفند 1389 که به عنوان بیماری کرون و کولیت اولسراتیو به تشخیص قطعی رسیدند؛ تحت انجام آندوسکوپی فوقانی قرار گرفتند و داده ها با استفاده از نرم افزارSPSS و آزمون آماری t-test تجزیه و تحلیل شدند. یافته ها: از30 کودک با تشخیص بیماری التهابی روده، تعداد 15 بیمار دچار کرون و مابقی کولیت اولسراتیو داشتند. نتایج مطالعه حاضر حاکی از درگیری ماکروسکوپی مری در 93 بیماران، درگیری معده در 87 و درگیری دئودنوم در 26 بیماران با تشخیص کرون بود. در بیماران کولیت اولسراتیو درگیری مری 80، معده 66 و دئودنوم 20 بود. از نظر میکروسکوپی در بیماران کرون درگیری مری 94، درگیری معده 80 و در نهایت درگیری دئودنوم 47 مشاهده شد. در بیماران کولیت اولسراتیو از نظر میکروسکوپی 94 درگیری مری، 87 درگیری معده و 67 درگیری دئودنوم داشتند. نتیجه گیری: با توجه به درصد قابل توجه درگیری دستگاه گوارش فوقانی در بیماران با بیماری التهابی روده، انجام آندوسکوپی در تمام بیماران جدا از نوع و محل درگیری و بررسی هیستوپاتولوژیک کاری منطقی و لازم بنظر می رسد

Probiotics for the Treatment of Pediatric Helicobacter Pylori Infection: A Randomized Double Blind Clinical Trial

Objective: Helicobacter pylori is recognized as a major etiological factor in the pathogenesis of gastritis and peptic ulcer disease. H. Pylori eradication has a failure rate of more than 30% in pediatric patients, particularly because of poor compliance, antibiotic resistance and occurrence of side-effects. This study was aimed to determine whether adding the probiotics to a standard anti-H. Pylori regimen could minimize the gastrointestinal side-effect prevalence and improve the eradication rate. Methods: Double-blind randomized placebo controlled study conducted at Children’s Medical Center in Tehran, Iran. Sixty six H. Pylori positive children were treated with a triple drug treatment protocol (omeprazole+amoxycillin+furazolidon) and randomly allocated to receive either probiotic or placebo. All patients underwent esophagogastroduodendoscopy. H. Pylori infection was diagnosed by either rapid urease test (RUT) or histology. H. Pylori status was assessed after 4-8 weeks of the completion of treatment with stool H. Pylori antigen test. The side effects of the treatment were determined in each group. Findings:. Mean age of patients was 9.09 (range 3‐14) years, 44 (65.7%) patients were boys (sex ratio 2:1). All 66 patients completed the course of treatment and follow-up. The rate of H. Pylori eradication was significantly higher in probiotic group (P=0.04). In probiotic supplemented children there was a lower rate of nausea/vomiting (P=0.02) and diarrhea (P=0.039) during treatment. Conclusion: This study showed that probiotics have positive effect on the eradication of H. Pylori infection. Adjuvant therapy with probiotic is recommended in order to reduce the frequency of antibiotic induced sideeffects during treatment with antibiotics

Vitamin D Deficiency among Female Nurses of Children’s Medical Center Hospital and Its Related Factors

Vitamin D deficiency is one of the most preventable challenges worldwide. The aim of this study was to determine the prevalence of vitamin D deficiency among female nurses working at Children’s Medical Center Hospital in Tehran, Iran, due to the risk factor of being a notably long period indoors and the fact that their health status may have consequences on the process of patients’ treatment. A total of 114 female nurses who were at least 20 years old entered the study voluntarily, and a questionnaire was applied to collect information on lifestyle and other factors associated with vitamin D deficiency. A sample of blood was taken to measure 25-hydroxyvitamin D (25-OHD) and cut off value to indicate deficiency was considered below 10ng/ml, and the amounts of 10-29ng/ml were declared insufficient. The mean of 25-OHD was 11.7±9.3ng/ml. A total of 79 subjects (69.3%) had a deficient level of vitamin D, 28 subjects (24.6%) had an insufficient level and only 7 subjects (6.1%) had sufficient level of vitamin D. The deficiency was more noticeable in the age group of 26-35 years old. Prevalence of vitamin D deficiency had a significant correlation with younger subjects (P<0.001). There was no significant association among other factors such as body mass index (BMI), health status complications, regular exercise, and duration of sun exposure. High prevalence of vitamin D deficiency in the study population leads to emphasise the need to screen health care workers for vitamin D levels

The Effect of Baclofen on Treatment of Infancy Gastro-esophageal Reflux Disorder

Objective: Transient lower esophageal sphincter relaxation (TLESR) is the major cause of gastroesophageal reflux disorder (GERD) in patient with reflux disease. GERD is the most common esophageal disorder in children. The GABA agonist baclofen decreases acid reflux through the inhibition of TLESRs and should similarly decrease non-acid reflux. The aim of this study was to evaluate the effect of baclofen on GERD in children. Methods: Thirty children with GERD were included in this clinical trial. Baclofen 0.25 mg/kg was given for three months. End points were assessed for weeks and months. Findings: Baclofen significantly improved the weight gain pattern and the mean of weight gain demonstrated a significant difference between base line value and weight on consequent months after therapy (P<0.0001). Restlessness showed a significant improvement between baseline and threes month after treatment (P<0.001).Vomiting significantly decreased on follow up visits (P<0.001). It is also increased the time and volume of feeding significantly 3 month after treatment (P<0.001). We have not found serious complications. Conclusion: Baclofen reduces the symptom of TLESRs and may have a role in treating GERD