43 research outputs found

    ASPEK-ASPEK LINGKUNGAN HIDUP DALAM KERJASAMA PEMBANGUNAN BERKELANJUTAN AUSTRALIA DAN INDONESIA ( 1992-1997)

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    ABSTRAK Skripsi ini meneliti tentang kerjasama pembangunan berkelanjutan Australia sebagai negara donor dan implikasi yang diperoleh Indonesia sebagai negara penerima bantuan pembangunan yang berwawasan lingkungan hidup. Dalam membahas penelitian ini digunakan peringkat analisis negarabangsa, dengan unit analisis pembangunan berkelanjutan dan unit eksplanasi Australia dan Indonesia. Penelitian ini menggunakan konsep kepentingan nasional, kebijakan luar negeri, dan pembangunan berkelanjutan. Teori yang digunakan adalah interdependensi, pembangunan seimbang, dan Human Capital Theory. Tipe penelitian yang digunakan adalah deskriptif-eksplanatif. Hipotesis yang diajukan dalam skripsi ini adalah kebijakan Australia dalam mendukung pelaksanaan pembangunan berkelanjutan dengan memfokuskan perhatian pada pembangunan sumber daya manusia terutama melalui pendidikan. Bagi Indonesia, seperti negara-negara miskin lainnya, selain permasalahan dana untuk pelaksanaan pembangunan berkelanjutan tersebut, juga mendapatkan tekanan yang terus meningkat dari pihak negara donor di dalam pelaksanaan kebijakan luar negerinya. Untuk menghadapi permasalahan tersebut Australia dan Indonesia harus menemukan solusi yang tepat dalam pengembangan pembangunan berwawasan lingkungan hidup dengan kerangka kerjasama yang lebih terbuka. Kata kunci: pembangunan berkelanjutan, interdependensi, dan Human Capital Theory

    Affected Family Members\u27 Communicative Management of Opioid Misuse Stigma: Applying and Rethinking the Stigma Management Communication Typology

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    Opioid misuse is a prevalent health problem in the United States with consequences extending past the person who misuses opioids to affected family members (AFM) through courtesy stigma. The goals of this study were to understand the stigma management communication (SMC) strategies employed by AFMs when they experience courtesy stigma and changes in strategies used over time. The findings from interviews with 34 AFMs suggest the SMC strategies they employ range from those that indicate acceptance of stigma and avoidance of stigma situations to strategies where AFMs actively challenge opioid misuse stigma. However, strategy use depended on the social context and AFMs’ perceptions of opioid misuse stigma at a given moment in time. Further, findings suggest changes in AFMs’ SMC strategies over time are related to changes in their perceptions of opioid misuse stigma. Theoretical and practical implications of how families manage stigma are discussed

    Infectious Pancreatic Necrosis Virus in Scottish Atlantic Salmon Farms, 1996–2001

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    The rapid growth of aquaculture has provided opportunities for the emergence of diseases. Programs designed to monitor these pathogens are useful for analysis of regional variation and trends, provided methods are standardized. Data from an official monitoring program were used to analyze the emergence of infectious pancreatic necrosis virus in Scottish salmon farms from 1996 to 2001. An annual increase in the prevalence of this virus was found in saltwater (10%) and freshwater sites (2% to 3%), with a much faster increase (6.5%) in Shetland’s freshwater sites. No significant increase in the virus was detected in the marine farms of southern mainland Scotland. However, the virus had become very prevalent at marine sites and was almost ubiquitous in Shetland by 2001, and thus the prevalence of this virus at marine sites may be underestimated. Because several diseases have emerged or are emerging in fish farming, aquaculture surveillance programs represent a rich potential source of data on emerging diseases

    Examining a staging model for anorexia nervosa: empirical exploration of a four stage model of severity.

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    Background: An illness staging model for anorexia nervosa (AN) has received increasing attention, but assessing the merits of this concept is dependent on empirically examining a model in clinical samples. Building on preliminary findings regarding the reliability and validity of the Clinician Administered Staging Instrument for Anorexia Nervosa (CASIAN), the current study explores operationalising CASIAN severity scores into stages and assesses their relationship with other clinical features. Method: In women with DSM-IV-R AN and sub-threshold AN (all met AN criteria using DSM 5), receiver operating curve (ROC) analysis (n = 67) assessed the relationship between the sensitivity and specificity of each stage of the CASIAN. Thereafter chi-square and post-hoc adjusted residual analysis provided a preliminary assessment of the validity of the stages comparing the relationship between stage and treatment intensity and AN sub-types, and explored movement between stages after six months (Time 3) in a larger cohort (n = 171). Results: The CASIAN significantly distinguished between milder stages of illness (Stage 1 and 2) versus more severe stages of illness (Stages 3 and 4), and approached statistical significance in distinguishing each of the four stages from one other. CASIAN Stages were significantly associated with treatment modality and primary diagnosis, and CASIAN Stage at Time 1 was significantly associated with Stage at 6 month follow-up. Conclusions: Provisional support is provided for a staging model in AN. Larger studies with longer follow-up of cases are now needed to replicate and extend these findings and evaluate the overall utility of staging as well as optimal staging models

    Multiway modeling and analysis in stem cell systems biology

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    <p>Abstract</p> <p>Background</p> <p>Systems biology refers to multidisciplinary approaches designed to uncover emergent properties of biological systems. Stem cells are an attractive target for this analysis, due to their broad therapeutic potential. A central theme of systems biology is the use of computational modeling to reconstruct complex systems from a wealth of reductionist, molecular data (e.g., gene/protein expression, signal transduction activity, metabolic activity, etc.). A number of deterministic, probabilistic, and statistical learning models are used to understand sophisticated cellular behaviors such as protein expression during cellular differentiation and the activity of signaling networks. However, many of these models are bimodal i.e., they only consider row-column relationships. In contrast, multiway modeling techniques (also known as tensor models) can analyze multimodal data, which capture much more information about complex behaviors such as cell differentiation. In particular, tensors can be very powerful tools for modeling the dynamic activity of biological networks over time. Here, we review the application of systems biology to stem cells and illustrate application of tensor analysis to model collagen-induced osteogenic differentiation of human mesenchymal stem cells.</p> <p>Results</p> <p>We applied Tucker1, Tucker3, and Parallel Factor Analysis (PARAFAC) models to identify protein/gene expression patterns during extracellular matrix-induced osteogenic differentiation of human mesenchymal stem cells. In one case, we organized our data into a tensor of type protein/gene locus link Ă— gene ontology category Ă— osteogenic stimulant, and found that our cells expressed two distinct, stimulus-dependent sets of functionally related genes as they underwent osteogenic differentiation. In a second case, we organized DNA microarray data in a three-way tensor of gene IDs Ă— osteogenic stimulus Ă— replicates, and found that application of tensile strain to a collagen I substrate accelerated the osteogenic differentiation induced by a static collagen I substrate.</p> <p>Conclusion</p> <p>Our results suggest gene- and protein-level models whereby stem cells undergo transdifferentiation to osteoblasts, and lay the foundation for mechanistic, hypothesis-driven studies. Our analysis methods are applicable to a wide range of stem cell differentiation models.</p

    Antennas for handheld satellite personal communicators

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    SIGLEAvailable from British Library Document Supply Centre-DSC:DXN028609 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

    Promising Practices in Supporting Student Development of Self-Determination Skills (NCSET Teleconference)

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    A transcript summarizing a teleconference on Florida's Self-Determination Initiative that helps educators support youth with disabilities in developing self-determination skills.NCSET is supported through cooperative agreement #H326J000005 with the U.S. Department of Education, Office of Special Education Programs. Opinions expressed herein do not necessarily reflect the policy or position of the U.S. Department of Education, and no official endorsement should be inferred
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