Is Brimonidine Tartrate Gel .5% Effective in Reducing Facial Erythema of Rosacea?

OBJECTIVE: The objective of this selective Evidence Based Medicine (EBM) review is to determine whether or not “Is Brimonidine Tartrate gel 0.5% effective in reducing facial erythema of Rosacea?” STUDY DESIGN: Review of two randomized controlled trials (RCT), and one 1-year longitudinal open-label study. DATA SOURCES: All studies were published in peer-reviewed journals found via the use of PubMed or Medline. OUTCOMES MEASURED: Patients were divided into two groups: those who received the Brimonidine Tartrate gel and those who received the vehicle (placebo) gel. Efficacy of Brimonidine tartrate gel was compared to the efficacy of the vehicle gel. Outcomes were measured at baseline and at various intervals post treatment using Clinician’s Erythema Assessment (CEA) and Patient’s Self-Assessment (PSA) scales. Both scales were designed as tools for evaluation of erythema. In the 1-year open label study, inflammatory lesion counts and telangiectasia were also evaluated to determine the long-term efficacy of the drug. Additionally, in this study, the subjects were asked to complete a questionnaire regarding the impact of rosacea on their social life at various points during the study. RESULTS: In both RCT, (Fowler – 2011 and Fowler – 2013) results of Brimonidine tartrate gel versus Vehicle gel reached statistical significance and proved to be an effective form of treatment in patients with facial erythema of Rosacea (p \u3c 0.001 and p CONCLUSION: Both RCT and one-year open label studies included in this review indicate that Brimonidine Tartrate gel 0.5% is an effective treatment for facial erythema of Rosacea in regards to quality of life and self-confidence due to the appearance

Meaning of migration, gender and identities in the lives of Asian Indian women: An exploratory study

The present study is an attempt at exploring meaning of migration in the lives of Asian Indian women. In personal narrative form, women provide an insight into the experiences that shape their lives as females growing up in India, reason for migration, and the changes brought forth by migration in aspects of redefining the self, the community, gender relations and functioning as members of a new society. The research problems identified for the present study deal with paucity of literature regarding migration issues of Asian Indian women in the field of psychology. There is also lack of information in the literature regarding issues of complexity, contradictions and ambiguity in understanding gender and migration experiences of Asian Indian women. The second problem that this study will address is methodological in how migration has been conceptualized and operationalized in psychology. The methodology in studying migration has moved towards quantifying cultural and experiential variables. It is felt that this is inadequate to understand processes, intricacies and idiosyncratic nuances of cultural definitions and choices. It also fails to allow for a ‘both and’ quality in existences and multiplicity in identities. For the purpose of the present study, the interview format was used to gather historical information about the participants\u27 lives and experiences. The researcher interviewed 6 migrant Asian Indian women in and around the suburbs of Philadelphia and New Jersey. A multi-session format was used for the interviews. The interviews revealed the complexity of person-context interactions and how they shape gender roles. Specifically, the women provided insights into multiple messages they received growing up and ways they attempted to cope, accept and resist. With reference to migration, this study reveals the connections between pre-migration experiences and later lives as well as shifts in roles that occur upon migration. The study also explores issues of balancing multiple identities, social concerns that confront them and perceived life stage outcomes

Meaning of migration, gender and identities in the lives of Asian Indian women: An exploratory study

The present study is an attempt at exploring meaning of migration in the lives of Asian Indian women. In personal narrative form, women provide an insight into the experiences that shape their lives as females growing up in India, reason for migration, and the changes brought forth by migration in aspects of redefining the self, the community, gender relations and functioning as members of a new society. The research problems identified for the present study deal with paucity of literature regarding migration issues of Asian Indian women in the field of psychology. There is also lack of information in the literature regarding issues of complexity, contradictions and ambiguity in understanding gender and migration experiences of Asian Indian women. The second problem that this study will address is methodological in how migration has been conceptualized and operationalized in psychology. The methodology in studying migration has moved towards quantifying cultural and experiential variables. It is felt that this is inadequate to understand processes, intricacies and idiosyncratic nuances of cultural definitions and choices. It also fails to allow for a ‘both and’ quality in existences and multiplicity in identities. For the purpose of the present study, the interview format was used to gather historical information about the participants\u27 lives and experiences. The researcher interviewed 6 migrant Asian Indian women in and around the suburbs of Philadelphia and New Jersey. A multi-session format was used for the interviews. The interviews revealed the complexity of person-context interactions and how they shape gender roles. Specifically, the women provided insights into multiple messages they received growing up and ways they attempted to cope, accept and resist. With reference to migration, this study reveals the connections between pre-migration experiences and later lives as well as shifts in roles that occur upon migration. The study also explores issues of balancing multiple identities, social concerns that confront them and perceived life stage outcomes