96 research outputs found

    Moving in next door: Network flooding as a side channel in cloud environments

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    The final publication is available at http://link.springer.com/chapter/10.1007/978-3-319-48965-0_56Co-locating multiple tenants' virtual machines (VMs) on the same host underpins public clouds' affordability, but sharing physical hardware also exposes consumer VMs to side channel attacks from adversarial co-residents. We demonstrate passive bandwidth measurement to perform traffic analysis attacks on co-located VMs. Our attacks do not assume a privileged position in the network or require any communication between adversarial and victim VMs. Using a single feature in the observed bandwidth data, our algorithm can identify which of 3 potential YouTube videos a co-resident VM streamed with 66% accuracy. We discuss defense from both a cloud provider's and a consumer's perspective, showing that effective defense is difficult to achieve without costly under-utilization on the part of the cloud provider or over-utilization on the part of the consumer.We would like to acknowledge the MIT PRIMES program and thank in particular Dr. Slava Gerovitch and Dr. Srini Devadas for their support. We are also grateful to Boston University, the Hariri Institute, and the Massachusetts Open Cloud. This paper is based upon work supported by the National Science Foundation under Grants No. 1414119 and 1413920

    Microbial Biofilms

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    Biofilms are the aggregation of microbial cells, which are associated with the surface in almost an irreversible manner. It exists in variety of forms like dental plaque, pond scum, or the slimy build up in sink. Biofilm formation involves sequence of steps like conditioning, attachment, metabolism, and detachment. Biofilm consists of water channels, EPS (Exopolysaccharide), and eDNA (Environmental DNA), which plays an important role in nutrient circulation, its development, and structure stabilization. Resistance of planktonic bacteria against antimicrobial agents gets increased on the formation of biofilm, which may be the presence of diffusive barrier EPS or neutralizing enzyme, cells undergoing starvation, or due to spore formation. There are numerous factors, which affects biofilm formation such as substratum effects, conditioning film on substratum, hydrodynamics, characteristics of the aqueous medium, cell characteristics, and environmental factors. Biofilm can cause industrial, medical, and household damage and is a reason for loss of billions of dollars every year. Development of biofilm on catheters, medical implants, and devices is a major cause of infections and diseases in humans. Examples include Plaque, Native Valve Endocarditis, Otitis media, Prostatitis, Cystic fibrosis, Periodontitis, Osteomyelitis, and many more

    Bike Location and Road Obstacle Tracking Using Smart Helmet

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    In India, most of the people prefer two wheelers compared to other form of vehicle due to simplicity and low cost. One important problem is bike riders suffer from inadequate roads and bad driving conditions. Other important problem with biker is that most of the time they don?t like to wear helmet which could be fatal when accidents happen. Since in India the usage of two wheelers is more as compared to four wheelers, it requires more attention as far as safety is concerned. Motorcycles have high rate of fatal accidents than automobiles or trucks and buses. According to some statistics serious head injuries can happen even in low speeds. Ninety percent of head injury cases are due to road traffic accidents, about 72 percent are youngsters in the age group of 18 to 40. So to overcome this problem we have introduced a smart helmet with additional features like road hazard warning, bike authentication. In the previous research work that focuses on the point that the bike will not get start if the rider is not wearing helmet, so we modified this feature and make ones bike secure at crucial time especially when one is away from the bike and somebody is trying to steal it. So, we recapitulated the above features and introduce the project with some more unique characteristics. The main aim of this project is to introduce the smart interactive robotic helmet with features such as road obstacle identification, bike authentication, would help the rider in detecting important traffic sounds like fire siren or horn and the smart helmet would warn the rider when hazard is ahead. In this research work, the helmet is designed in such a way that it would provide more security to the rider hence the user is attracted towards the helmet because of its peculiar characteristics. If the rider runs on the bad intersection path, he could record for the present and upcoming road obstacle which is saved in mp3 format and can play that recording by pressing the button when he goes on same path again

    Study of the profile of stroke in a tertiary-care hospital in the sub-Himalayan region in north India

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    Background: Rapid urbanization of rural areas is predicted to increase the incidence of risk factors for vascular events such as stroke among the ruralites. A different culture, beliefs, terrain, and climatic conditions of Himachal Pradesh may have an impact on the profile of stroke. Objectives: To study the profile and the various risk factors of stroke in the sub-Himalayan region of north India. Material and Methods: It was an observational cross-sectional study conducted at the Department of Medicine, R.P. Government Medical College, Kangra, Himachal Pradesh, for a duration of 12 months, from June 2012 to May 2013. Consecutive patients presenting to the hospital with signs and symptoms of stroke were included in the study. Detailed history and clinical examination was carried out in all patients. CT scan, routine blood examination, and lipid profile were evaluated in all patients. Results: Total number of patients who presented with stroke in a year was 374. It formed 4.0% of the total hospital admissions in medical wards. The mean age of stroke patients was 66.17±12.9 years. Of the total patients, 254 (67.9%) were males and 120 (32%) were females; 127 patients (33.9%) presented between 6 am and 12 pm. The majority of patients presented in winter months, from November to January. Average delay in the presentation to hospital was 29 h. Only 79 (21.1%) patients presented within 3 h. Among the patients, 342 (91.4%) belonged to rural area, 61.4% had an infarct, and 38.6% had intracerebral bleed. The most common symptoms reported were weakness in 276 (73%) followed by speech abnormality in 53%. Hypertension as a risk factor was found in 174 (46.5%); 155 patients (41.4%) were smokers; and diabetes was present in 61 patients (16.4%). Average cholesterol level was 176±54.99 mg/dl, and average triglyceride level was 339 mg/dl. Conclusions: The major strength in our study was the predominance of rural population. The state has witnessed an increase in the incidence of stroke. Elderly population is predominantly affected. Average delay in presentation was 29 h, which is substantially high. Majority of the events occurred in winter months

    Influence of sex on the profile of acute coronary syndrome: a tertiary care hospital based study from the Sub-Himalayan region in North India

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    Background: Coronary events presents about ten years later in women than men. There exist distinct gender differences in terms of presentation of symptoms, validity of diagnostic tests and complications. Methods: The study was conducted in the department of medicine R.P. Govt. Medical College (RPGMC) Himachal Pradesh. Consecutive 300 patients of acute coronary syndrome from June 2011 to June 2012 were included in the study. Demographical profile was recorded with focused clinical examination and relevant investigation with lipid profile was done.Results:Among the study population of 300 individuals, 201 (67%) were males and 99 (33%) were females. The mean age among male patients was 61.3±11.7 years and in female patients the mean age was 65.6±11.20 years. 68.8% of females presented after 60 yrs of age. Dyslipidemia was the commonest risk factor followed by hypertension and obesity. 12.2% of female patients were smokers. Chest pain was the commonest presenting symptom seen in 82% cases. There was mean delay of 31.0±54.5 hrs in the presentation of females for treatment. ST Elevated Myocardial Infarction occurred less frequently in females.Conclusions: Acute coronary syndrome is more age dependent in females. The predominance of dyslipidemia, hypertension and obesity as risk factors gives a message for primary care physicians to create awareness for the prevention of Acute Coronary Syndrome. The atypical symptoms should be recognised early which should further prevent the delay in presentation.

    USE OF RECYCLED PLASTIC AS REPLACEMENT OF FINE AGGREGATE IN STRUCTURAL CONCRETE

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    Now a days disposal of dissipate plastic is one of the major green problem all above the world. The objective of this review paper is to examine the usefulness of using waste plastic as fine aggregate substitute in concrete mixtures. The compressive and tensile strength of a variety of concrete specimens were tested to establish how the amalgamation of recycled plastic as a replacement of fine aggregate would affect the expansion of strength in the mixes. In this reading plastic waste was mixed with cement concrete in a variety of scope such as 0%-15% and the M20 grade test specimen were casted to learning the behavior of plastic mixed concrete. All stages of plastic replacement show a perceptible diminish in compressive strength and tensile strength. https://journalnx.com/journal-article/2015071

    Study of LV functions in patients of subclinical hypothyroidism in patients coming to rural medical college of Sub-Himalayan region of India

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    Background:Subclinical hypothyroidism (SCH) is a common disorder and has been implicated in increased cardiovascular morbidity and mortality. Therefore, it is important to study the effect of SCH on cardiac morphology and function. Thus, present study titled “Study of LV functions in patients of subclinical hypothyroidism in patients coming to rural medical of sub-Himalayan region of India” was conducted in the department of medicine, Rajinder Prasad government medical Tanda over a period of three years from December, 2010 to November, 2013 to study left ventricular function in subclinical hypothyroidism.Methods: The study was conducted in the department of medicine, Rajinder Prasad government medical Tanda over a period of three years from December, 2010 to November, 2013 to study left ventricular function in subclinical hypothyroidism. The data was analysed using computer software Epi-info version 6.0 and SPSS version 12.0 for Windows. Descriptive characteristics were presented as percentages for quantitative variables including measurement of thyroid hormones and ejection fraction. Mean and standard deviation were reported.Results:Diastolic parameters were markedly altered, mainly isovolumic relaxation time, which was increased and reduction of E/A wave ratio (1.Conclusions:Implication for echocardiography in SCH patients observed were that early recognition of silent diastolic dysfunction can be done. We can institute L-thyroxinee therapy which has been found to reverse diastolic dysfunction of heart along with improvement in lipid levels, decreased systemic vascular resistance, diastolic hypertension and coagulation profile. SCH, invariably affects heart and sooner or later and leads to diastolic dysfunction. Early recognition by echocardiography and then treatment with L-thyroxinee is indicated.

    Physics of eccentric binary black hole mergers: A numerical relativity perspective

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    Gravitational wave observations of eccentric binary black hole mergers will provide unequivocal evidence for the formation of these systems through dynamical assembly in dense stellar environments. The study of these astrophysically motivated sources is timely in view of electromagnetic observations, consistent with the existence of stellar mass black holes in the globular cluster M22 and in the Galactic center, and the proven detection capabilities of ground-based gravitational wave detectors. In order to get insights into the physics of these objects in the dynamical, strong-field gravity regime, we present a catalog of 89 numerical relativity waveforms that describe binary systems of non-spinning black holes with mass-ratios 1≤q≤101\leq q \leq 10, and initial eccentricities as high as e0=0.18e_0=0.18 fifteen cycles before merger. We use this catalog to quantify the loss of energy and angular momentum through gravitational radiation, and the astrophysical properties of the black hole remnant, including its final mass and spin, and recoil velocity. We discuss the implications of these results for gravitational wave source modeling, and the design of algorithms to search for and identify eccentric binary black hole mergers in realistic detection scenarios.Comment: 11 pages, 5 figures, 2 appendices. A visualization of this numerical relativity waveform catalog is available at https://gravity.ncsa.illinois.edu/products/outreach/; v2: 13 pages, 5 figures, calculations for angular momentum emission and recoil velocities are now included, references added. Accepted to Phys. Rev.

    CRISPR-Cas9: Role in Processing of Modular Metabolic Engineered Bio-Based Products

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    Biogenetic engineering is a significant technology to sensibly manage microbial metabolic product factories. Genome modification methods for efficiently controlling and modifying genes at the genome level have progressed in biogenetic engineering during the last decade. CRISPR is genome editing technology that allows for the modification of organisms’ genomes. CRISPR and its related RNA-guided endonuclease are versatile advanced immune system frameworks for defending against foreign DNA and RNAs. CRISPR is efficient, accessible, and trustworthy genomic modification tool in unparalleled resolution. At present, CRISPR-Cas9 method is expanded to industrially manipulate cells. Metabolically modified organisms are quickly becoming interested in the production of different bio-based components. Here, chapter explore about the control productivity of targeted biomolecules in divergent cells based on the use of different CRISPR-related Cas9
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