713 research outputs found

    Fast Frame-Based Image Deconvolution Using Variable Splitting and Constrained Optimization

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    We propose a new fast algorithm for solving one of the standard formulations of frame-based image deconvolution: an unconstrained optimization problem, involving an ℓ2\ell_2 data-fidelity term and a non-smooth regularizer. Our approach is based on using variable splitting to obtain an equivalent constrained optimization formulation, which is then addressed with an augmented Lagrangian method. The resulting algorithm efficiently uses a regularized version of the Hessian of the data fidelity term, thus exploits second order information. Experiments on a set of image deblurring benchmark problems show that our algorithm is clearly faster than previous state-of-the-art methods.Comment: Submitted to the 2009 IEEE Workshop on Statistical Signal Processin

    A Bathtub Curve from Nonparametric Model

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    This paper presents a nonparametric method to obtain the hazard rate "Bathtub curve" for power system components. The model is a mixture of the three known phases of a component life, the decreasing failure rate (DFR), the constant failure rate (CFR) and the increasing failure rate (IFR) represented by three parametric Weibull models. The parameters are obtained from a simultaneous fitting process of the model to the Kernel nonparametric hazard rate curve. From the Weibull parameters and failure rate curves the useful lifetime and the characteristic lifetime were defined. To demonstrate the model the historic time-to-failure of distribution transformers were used as an example. The resulted "Bathtub curve" shows the failure rate for the equipment lifetime which can be applied in economic and replacement decision models

    A Bathtub Curve from Nonparametric Model

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    This paper presents a nonparametric method to obtain the hazard rate "Bathtub curve" for power system components. The model is a mixture of the three known phases of a component life, the decreasing failure rate (DFR), the constant failure rate (CFR) and the increasing failure rate (IFR) represented by three parametric Weibull models. The parameters are obtained from a simultaneous fitting process of the model to the Kernel nonparametric hazard rate curve. From the Weibull parameters and failure rate curves the useful lifetime and the characteristic lifetime were defined. To demonstrate the model the historic time-to-failure of distribution transformers were used as an example. The resulted "Bathtub curve" shows the failure rate for the equipment lifetime which can be applied in economic and replacement decision models

    Relationship of arterial and exhaled CO2 during elevated artificial pneumoperitoneum pressure for introduction of the first trocar.

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    The present study evaluated the correlation between arterial CO2 and exhaled CO2 during brief high-pressure pneumoperitoneum. Patients were randomly distributed into two groups: P12 group (n=30) received a maximum intraperitoneal pressure of 12mmHg, and P20 group (n=37) received a maximum intraperitoneal pressure of 20mmHg. Arterial CO2 was evaluated by radial arterial catheter and exhaled CO2 was measured by capnometry at the following time points: before insufflation, once intraperitoneal pressure reached 12mmHg , 5 minutes after intraperitoneal pressure reached 12mmHg for the P12 group or 20mmHg for the P20 group, and 10 minutes after intraperitoneal pressure reached 12mmHg for the P12 group or when intraperitoneal pressure had decreased from 20mmHg to 12mmHg, for the P20 group. During brief durations of very high intraperitoneal pressure (20mmHg), there was a strong correlation between arterial CO2 and exhaled CO2. Capnometry can be effectively used to monitor patients during transient increases in artificial pneumoperitoneum pressure

    Metabolic plasticity for subcutaneous fat accumulation in a long-distance migratory bird traced by 2 H 2 O

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    The migrant black-tailed godwit (Limosa limosa) traditionally used natural wetlands in the Iberian Peninsula to prepare for migratory flights by feeding mainly in estuaries. In recent decades, this species has become increasingly dependent on rice fields, thereby relying on a plant-based diet for fuelling. Dietary fatty acids (FA) seem to be determinant to the composition of accumulated subcutaneous fat in migratory birds. It is still unclear whether metabolic plasticity allows for modification and/or synthesis of FA, contributing to a lipid profile that enables a successful migratory performance. Deuterated water was administered to captive black-tailed godwits submitted to two diets (fly larvae versus rice) and the incorporation of deuterium (2H) into subcutaneous triglycerides was analyzed by NMR. A recently developed localized biopsy method for sampling subcutaneous fat was employed with later successful release of all birds into the wild. The average chemical structure reflected mostly a mixture of saturated and monounsaturated 16- and 18-carbon FA, a profile frequently found in migrant birds. Significantly higher levels of polyunsaturated FA, as well as detectable levels of n-3 FA, were observed in fly-larvae-fed birds. Excess 2H-enrichments in FA revealed significantly higher rates of fractional de novo lipogenesis and FA desaturation capacity in rice-fed birds. This novel and non-lethal tracer method revealed the capacity of this species to alter its lipid metabolism to compensate for a poorer dietary lipid contribution. Because of its versatility, adapting this method to other scenarios and/or other migratory species is considered feasible and cost-effective.The authors acknowledge financial support from Fundacao para a Ciencia e Tecnologia (FCT) in the form of fellowships to I.V. (SFRH/BPD/90032/2012), P.M.A. (SFRH/BD/69238/2010), A.D.R. (SFRH/BD/74228/2010) and J.A.A. (SFRH/BPD/91527/2012) and research project EXCL/DTP-PIC/0069/2012. NMR data were collected at the UC-NMR facility that is supported by FEDER and FCT (RECI/QEQ-QFI/0168/2012, CENTRO-07-CT62-FEDER-002012) and Rede Nacional de Ressonancia Magnetica Nuclear (RNRMN).Peer Reviewe

    Efectos de la comunidad de origen en el participante de comunidades virtuales de marca

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    Os benefĂ­cios das empresas em manterem comunidades virtuais de marca prĂłprias versus os provenientes das comunidades criadas pelos consumidores permanecem desconhecidos. Esse estudo testa o efeito moderador do tipo de gestĂŁo da comunidade no impacto da homogeneidade psicogrĂĄfica percebida, da disponibilidade de avenidas virtuais e do relacionamento com a marca sobre as influĂȘncias da comunidade e as intençÔes dos participantes da comunidade. Os dados provĂȘm de 555 participantes ativos de duas grandes comunidades virtuais para o game XBOX no Brasil. Os resultados comprovam que a gestĂŁo da comunidade de origem Ă© moderadora de todas as relaçÔes consideradas. Apontam, tambĂ©m, que alguns dos efeitos mais favorĂĄveis para a empresa ocorrem na comunidade gerida pelos consumidores. A lealdade Ă  marca, porĂ©m, Ă© maior para membros da comunidade oficial. O estudo indica como as empresas podem se beneficiar de comunidades geridas por consumidores.The question about the effectiveness of companies in maintaining their own communities versus benefiting from the ones owned by consumers remains open. We examine differences between firm-managed and customer-managed brand communities regarding the impact of perceived psychographic homogeneity, availability of virtual avenues and relationship with the brand on the community’s influence on members and the assessments and intentions of community participants. Data were obtained from 555 respondents in two leading Microsoft XBOX brand communities in Brazil. Results indicate that management of the community of origin is the moderator of all considered relationships. Also, the most favorable effects for the company occur in the community that is not directly controlled and managed by the company itself. Brand loyalty, however, is higher for members of the official brand community. Guidelines on how companies can benefit from consumer-managed communities are discussed.Los beneficios de las empresas al mantener comunidades virtuales de marca propia versus los provenientes de las comunidades creadas por los consumidores permanecen desconocidos. Este estudio prueba el efecto moderador del tipo de gestiĂłn de la comunidad en el impacto de la homogeneidad sicogrĂĄfica percibida, de la disponibilidad de avenidas virtuales y de la relaciĂłn con la marca sobre las influencias de la comunidad y las intenciones de los participantes de la comunidad. Los datos provienen de 555 participantes activos de dos grandes comunidades virtuales para el game XBOX en Brasil. Los resultados comprueban que la gestiĂłn de la comunidad de origen es moderadora de todas las relaciones consideradas. Apuntan tambiĂ©n que algunos de los efectos mĂĄs favorables para la empresa ocurren en la comunidad gestionada por los consumidores. La lealtad a la marca, no obstante, es mayor entre miembros de la comunidad oficial. El estudio indica cĂłmo las empresas pueden beneficiarse con las comunidades gestionadas por consumidores

    Control algorithms based on the active and non-active currents for a UPQC without series transformers

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    This study presents control algorithms for a new unified power quality conditioner (UPQC) without the series transformers that are frequently used to make the insertion of the series converter of the UPQC between the power supply and the load. The behaviour of the proposed UPQC is evaluated in presence of voltage imbalances, as well as under non-sinusoidal voltage-and current conditions. The presented algorithms derive from the concepts involving the active and non-active currents, together with a phase-locked-loop circuit. Based on these real-time algorithms, and considering the proposed hardware topology, the UPQC is able to compensate the harmonic components of the voltages and currents, correct the power factor, and keep the load voltages regulated, all of this in a dynamic way, responding instantaneously to changes in the loads or in the electrical power system. The control algorithms were distributed in a two-DSP digital control architecture, without any communication between them. Consequently, can be increased the sampling frequency of the acquired voltages and currents and improve the UPQC performance. Furthermore, some constraints of the proposed UPQC are evidenced, particularly when the main voltages are imbalanced. Simulation and experimental results are presented to verify the UPQC performance under transient and steady state conditions.info:eu-repo/semantics/publishedVersio

    Understanding how birds rebuild fat stores during migration: insights from an experimental study

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    Publisher's version (Ăștgefin grein).Mechanisms underlying fat accumulation for long-distance migration are not fully understood. This is especially relevant in the context of global change, as many migrants are dealing with changes in natural habitats and associated food sources and energy stores. The continental Black-tailed godwit Limosa limosa limosa is a long-distance migratory bird that has undergone a considerable dietary shift over the past few decades. Historically, godwits fed on an animal-based diet, but currently, during the non-breeding period godwits feed almost exclusively on rice seeds. The latter diet may allow building up of their fuel stores for migration by signifcantly increasing de novo lipogenesis (DNL) activity. Here, we performed an experiment to investigate lipid fux and the abundance of key enzymes involved in DNL in godwits, during fasting and refueling periods at the staging site, while feeding on rice seeds or fy larvae. Despite no signifcant diferences found in enzymatic abundance (FASN, ME1, ACC and LPL) in stored fat, experimental godwits feeding on rice seeds presented high rates of DNL when compared to fy-larvae fed birds (~35 times more) and fasted godwits (no DNL activity). The increase of fractional DNL in godwits feeding on a carbohydrate-rich diet can potentially be enhanced by the fasting period that stimulates lipogenesis. Although requiring further testing, these recent fndings provide new insights into the mechanisms of avian fat accumulation during a fasting and refueling cycle and associated responses to habitat and dietary changes in a migratory species.Te authors acknowledge fnancial support from FundacÌ§ĂŁo para a Ciencia e Tecnologia (FCT) in the form of fellowships to PMA (SFRH/BD/69238/2010), IV (SFRH/BPD/90032/2012) and JAA (SFRH/BPD/91527/2012) and research Project CGL2017-89009-P. NMR data were collected at the UC-NMR facility that is supported by FEDER and FCT (RECI/QEQ-QFI/0168/2012, CENTRO-07-CT62-FEDER-002012) and Rede Nacional de Ressonancia Magnética Nuclear (RNRMN). Tis study benefted from funding by the strategic program of MARE, fnanced by FCT (UID/MAR/04292/2019), and by FTC/MCTES to CESAM, (UID/AMB/50017 – POCI01-0145-FEDER-007638), through national funds.Peer Reviewe

    Prophylactic Treatment With Simvastatin Modulates the Immune Response and Increases Animal Survival Following Lethal Sepsis Infection

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    Chronic use of statins may have anti-inflammatory action, promoting immunomodulation and survival in patients with sepsis. This study aimed to analyze the effects of pretreatment with simvastatin in lethal sepsis induced by cecal ligation and puncture (CLP). Male Swiss mice received prophylactic treatment with simvastatin or pyrogen-free water orally in a single daily dose for 30 days. After this period, the CLP was performed. Naïve and Sham groups were performed as non-infected controls. Animal survival was monitored for 60 h after the CLP. Half of mice were euthanized after 12 h to analyze colony-forming units (CFUs); hematological parameters; production of IL-10, IL-12, IL-6, TNF-α, IFN-γ, and MCP-1; cell counts on peritoneum, bronchoalveolar lavage (BAL), bone marrow, spleen, and mesenteric lymph node; immunephenotyping of T cells and antigen presenting cells and production of hydrogen peroxide (H2O2). Simvastatin induced an increase in survival and a decrease in the CFU count on peritoneum and on BAL cells number, especially lymphocytes. There was an increase in the platelets and lymphocytes number in the Simvastatin group when compared to the CLP group. Simvastatin induced a greater activation and proliferation of CD4+ T cells, as well as an increase in IL-6 and MCP-1 production, in chemotaxis to the peritoneum and in H2O2 secretion at this site. These data suggest that simvastatin has an impact on the survival of animals, as well as immunomodulatory effects in sepsis induced by CLP in mice
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