Interpretation of the variability of the <i>β</i> Cephei star <i>λ</i> Scorpii. I. The multiple character

We derive accurate values of the orbital parameters of the close binary β Cephei star λ Scorpii. Moreover, we present the first determination of the properties of the triple system to which λ Scorpii belongs. Our analysis is based on a time series of 815 high-resolution spectra, covering a timespan of 14 years. We find a close orbit of 5d.9525days (e=0.26) and a wide orbit of approximately 1082d days (e=0.23). The orbital parameters of the triple star and a spectrum synthesis lead us to conclude that the system is composed of two early-type B stars and a low-mass pre-main-sequence star rather than containing an ultra-massive white dwarf as claimed before. Our proposed configuration is compatible with population synthesis. The radial velocity variations of the primary allow us to confirm the presence of at least one pulsation mode with frequency 4.679410 c d-1 which is subject to the light-time effect in the triple system. A detailed analysis of the complex line-profile variations is described in a subsequent paper

The functional role of temperate forest understorey vegetation in a changing world

Temperate forests cover 16% of the global forest area. Within these forests, the understorey is an important biodiversity reservoir that can influence ecosystem processes and functions in multiple ways. However, we still lack a thorough understanding of the relative importance of the understorey for temperate forest functioning. As a result, understoreys are often ignored during assessments of forest functioning and changes thereof under global change. We here compiled studies that quantify the relative importance of the understorey for temperate forest functioning, focussing on litter production, nutrient cycling, evapotranspiration, tree regeneration, pollination and pathogen dynamics. We describe the mechanisms driving understorey functioning and develop a conceptual framework synthesizing possible effects of multiple global change drivers on understorey-mediated forest ecosystem functioning. Our review illustrates that the understorey's contribution to temperate forest functioning is significant but varies depending on the ecosystem function and the environmental context, and more importantly, the characteristics of the overstorey. To predict changes in understorey functioning and its relative importance for temperate forest functioning under global change, we argue that a simultaneous investigation of both overstorey and understorey functional responses to global change will be crucial. Our review shows that such studies are still very scarce, only available for a limited set of ecosystem functions and limited to quantification, providing little data to forecast functional responses to global change

Relating land cover and spatial distribution of nephropathia epidemica and Lyme borreliosis in Belgium

Lyme borreliosis (LB) and nephropathia epidemica (NE) are zoonoses resulting from two different transmission mechanisms and the action of two different pathogens: the bacterium Borrelia burgdorferi and the Puumala virus, respectively. The landscape configuration is known to influence the spatial spread of both diseases by affecting vector demography and human exposure to infection. Yet, the connections between landscape and disease have rarely been quantified, thereby hampering the exploitation of land cover data sources to segment areas in function of risk. This study implemented a data-driven approach to relate land cover metrics and an indicator of NE/LB risk at different scales of observation of the landscape. Our results showed the suitability of the modeling approach (r2 &gt; 0.75, ¿ &lt;0.001) and highlighted the relevance of the scale of observation in the set of landscape attributes found to influence disease risk as well as common and specific risk factors of NE and LB

Assessment of the burden of outpatient clinic and MRI-guided needle muscle biopsies as reported by patients with facioscapulohumeral muscular dystrophy.

Muscle biopsies are used in clinical trials to measure target engagement of the investigational product. With many upcoming therapies for patients with facioscapulohumeral dystrophy (FSHD), the frequency of biopsies in FSHD patients is expected to increase. Muscle biopsies were performed either in the outpatient clinic using a Bergström needle (BN-biopsy) or in a Magnetic Resonance Imaging machine (MRI-biopsy). This study assessed the FSHD patients' experience of biopsies using a customized questionnaire. The questionnaire was sent to all FSHD patients who had undergone a needle muscle biopsy for research purposes, inquiring about biopsy characteristics and burden, and willingness to undergo a subsequent biopsy. Forty-nine of 56 invited patients (88%) completed the questionnaire, reporting on 91 biopsies. The median pain score (scale 0-10) during the procedure was 5 [2-8], reducing to 3 [1-5] and 2 [1-3] after one and 24 h, respectively. Twelve biopsies (13.2%) resulted in complications, eleven resolved within 30 days. BN-biopsies were less painful compared to MRI-biopsies (median NRS: 4 [2-6] vs. 7 [3-9], p = 0.001). The burden of needle muscle biopsies in a research setting is considerate and should not be underestimated. MRI-biopsies have a higher burden compared to BN-biopsies

Kikkermuizenoorlog. Katmuizenoorlog /

Kikkermuizenoorlog / Pseudo-Homerus. Katmuizenoorlog / Theodoros Prodromo

Large-sample assessment of varying spatial resolution on the streamflow estimates of the wflowsbm hydrological model

Distributed hydrological modelling moves into the realm of hyper-resolution modelling. This results in a plethora of scaling-related challenges that remain unsolved. To the user, in light of model result interpretation, finer-resolution output might imply an increase in understanding of the complex interplay of heterogeneity within the hydrological system. Here we investigate spatial scaling in the form of varying spatial resolution by evaluating the streamflow estimates of the distributed wflow_sbm hydrological model based on 454 basins from the large-sample CAMELS data set. Model instances are derived at three spatial resolutions, namely 3 km, 1 km, and 200 m. The results show that a finer spatial resolution does not necessarily lead to better streamflow estimates at the basin outlet. Statistical testing of the objective function distributions (Kling–Gupta efficiency (KGE) score) of the three model instances resulted in only a statistical difference between the 3 km and 200 m streamflow estimates. However, an assessment of sampling uncertainty shows high uncertainties surrounding the KGE score throughout the domain. This makes the conclusion based on the statistical testing inconclusive. The results do indicate strong locality in the differences between model instances expressed by differences in KGE scores of on average 0.22 with values larger than 0.5. The results of this study open up research paths that can investigate the changes in flux and state partitioning due to spatial scaling. This will help to further understand the challenges that need to be resolved for hyper-resolution hydrological modelling.Water Resource

Explanations for nitrogen decline

Environmental Biolog