Estudos Artísticos

A arte inclui no seu sistema os mesmos processos que reproduzem o poder ou que renovam as suas retóricas através de astúcias de resistência. Criou-se me tempos a proposta radical de uma arte emancipada, independente de referencialidade para além dos valores plásticos. Esta radicalidade escondia afinal um conformismo otimista e modernista: a arte “abstrata” era conservadora, decorativa, e não incomodava afinal ninguém. Aqui se mostra a oportunidade deste desafio, da chamada de artigos que esta Revista Croma 14 convocou: o desafio é entrar no caleidoscópio das ilusões sem perder o norte, sem abdicar do sentido último da cultura, que é mais humanidade, mais inteira, mais consciente.info:eu-repo/semantics/publishedVersio

Enteric viruses in HIV-1 seropositive and HIV-1 seronegative children with diarrheal diseases in Brazil

Submitted by Sandra Infurna ([email protected]) on 2018-02-12T15:23:07Z No. of bitstreams: 1 marise_miagostovich_etal_IOC_2017.pdf: 2240909 bytes, checksum: e2949425400d04112ba26e666462f386 (MD5)Approved for entry into archive by Sandra Infurna ([email protected]) on 2018-02-12T15:34:17Z (GMT) No. of bitstreams: 1 marise_miagostovich_etal_IOC_2017.pdf: 2240909 bytes, checksum: e2949425400d04112ba26e666462f386 (MD5)Made available in DSpace on 2018-02-12T15:34:17Z (GMT). No. of bitstreams: 1 marise_miagostovich_etal_IOC_2017.pdf: 2240909 bytes, checksum: e2949425400d04112ba26e666462f386 (MD5) Previous issue date: 2017Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Escritório regionao Piauí. Teresina, PI, BrasilFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil.Hospital Municipal Jesus. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil.Diarrheal diseases (DD) have distinct etiological profiles in immune-deficient and immunecompetent patients. This study compares detection rates, genotype distribution and viral loads of different enteric viral agents in HIV-1 seropositive (n = 200) and HIV-1 seronegative (n = 125) children hospitalized with DD in Rio de Janeiro, Brazil. Except for group A rotavirus (RVA), which were detected through enzyme immunoassay, the other enteric viruses (norovirus [NoV], astrovirus [HAstV], adenovirus [HAdV] and bocavirus [HBoV]) were detected through PCR or RT-PCR. A quantitative PCR was performed for RVA, NoV, HAstV, HAdV and HBoV. Infections with NoV (19% vs. 9.6%; p<0.001), HBoV (14% vs. 7.2%; p = 0.042) and HAdV (30.5% vs. 14.4%; p<0.001) were significantly more frequent among HIV-1 seropositive children. RVA was significantly less frequent among HIV-1 seropositive patients (6.5% vs. 20%; p<0.001). Similarly, frequency of infection with HAstV was lower among HIV-1 seropositive children (5.5% vs. 12.8%; p = 0.018). Among HIV-1 seropositive children 33 (16.5%) had co-infections, including three enteric viruses, such as NoV, HBoV and HAdV (n = 2) and NoV, HAstV and HAdV (n = 2). The frequency of infection with more than one virus was 17 (13.6%) in the HIV-1 negative group, triple infection (NoV + HAstV + HBoV) being observed in only one patient. The median viral load of HAstV in feces was significantly higher among HIV-1 positive children compared to HIV-1 negative children. Concerning children infected with RVA, NoV, HBoV and HAdV, no statistically significant differences were observed in the medians of viral loads in feces, comparing HIV-1 seropositive and HIV-1 seronegative children. Similar detection rates were observed for RVA, HAstV and HAdV, whilst NoV and HBoV were significantly more prevalent among children with CD4+ T lymphocyte count below 200 cells/mm3. Enteric viruses should be considered an important cause of DD in HIV-1 seropositive children, along with pathogens more classically associated with intestinal infections in immunocompromised hosts

Rate of detection and fecal viral load of different enteric virus in fecal samples obtained from HIV-1 seropositive children by level of CD4⁺ T lymphocyte count in Rio de Janeiro, Brazil.

<p>Rate of detection and fecal viral load of different enteric virus in fecal samples obtained from HIV-1 seropositive children by level of CD4⁺ T lymphocyte count in Rio de Janeiro, Brazil.</p

Enteric virus detection in HIV-1 seropositive children and HIV-1 seronegative children hospitalized with diarrheal diseases by age group in Rio de Janeiro, Brazil.

<p>Enteric virus detection in HIV-1 seropositive children and HIV-1 seronegative children hospitalized with diarrheal diseases by age group in Rio de Janeiro, Brazil.</p

Fecal viral loads of enteric viruses in HIV-1 seropositive and seronegative children hospitalizaded with diarrheal diseases in Rio de Janeiro, Brazil.

<p>Fecal viral loads of enteric viruses in HIV-1 seropositive and seronegative children hospitalizaded with diarrheal diseases in Rio de Janeiro, Brazil.</p

Genotype distribution of different enteric viruses in fecal samples obtained from 123 HIV-1 seropositive children (n = 200 fecal samples) and 125 HIV-1 seronegative children ((n = 125 fecal samples) hospitalized with diarrheal diseases in Rio de Janeiro, Brazil.

<p>Genotype distribution of different enteric viruses in fecal samples obtained from 123 HIV-1 seropositive children (n = 200 fecal samples) and 125 HIV-1 seronegative children ((n = 125 fecal samples) hospitalized with diarrheal diseases in Rio de Janeiro, Brazil.</p

Detection of multiple enteric viruses in fecal samples from 123 HIV-1 seropositive children (n = 200 fecal samples) and 125 HIV-1 seronegative children ((n = 125 fecal samples) hospitalized with diarrheal diseases in Rio de Janeiro, Brazil.

<p>Detection of multiple enteric viruses in fecal samples from 123 HIV-1 seropositive children (n = 200 fecal samples) and 125 HIV-1 seronegative children ((n = 125 fecal samples) hospitalized with diarrheal diseases in Rio de Janeiro, Brazil.</p

Oligonucleotide primers and probes used for viral detection, quantification and molecular characterization.

<p>Oligonucleotide primers and probes used for viral detection, quantification and molecular characterization.</p