Biological risks in professionals working in the mobile urgency service

This descriptive, cross-sectional study aims to evaluate the biological risks among professionals who work in the Mobile Emergency Service of the Metropolitan Region of São Luís - MA. The data were collected from 177 professionals from basic and advanced support units between February and April 2018, using a structured questionnaire.  While a high prevalence of exposure to biological risks was observed among all the subjects, men were found to be at a higher risk. The main source of contamination was blood, mainly affecting the whole skin during the procedure of immobilization. It was evidenced that most of the subjects did not complete the accident report and did not adhere to any post-exposure protocols. It is believed that the development of educational, safety and health measures can minimize the occupational hazards and accidents among the SAMU professionals, who are providers of indispensable service to society, even if susceptible to various environmental risks

Physical Activities Pattern among Brazilian Adults: Results of Phone Survey, 2006

O estudo descreve as características do padrão de atividade física da população adulta das capitais de Estados brasileiros e do Distrito Federal em 2006. Os dados foram coletados pelo sistema de vigilância de fatores de risco e proteção para doenças crônicas por inquérito telefônico (Vigitel) em uma amostra probabilística da população com 18 ou mais anos de idade (n=54.369). Foram analisados dois indicadores: ativo no lazer; e sedentário. Os indivíduos ativos no lazer foram 14,9%, a maioria homens. A caminhada é a modalidade mais comum, para ambos os sexos. A freqüência de ativos no lazer aumenta com a escolaridade e diminui com a idade. O sedentarismo já atingiu 29,2% da população adulta, com maior freqüência no sexo masculino, e aumenta com a idade e com a escolaridade. O perfil de atividade física é insatisfatório em todas as cidades, o que determina a necessidade de mais esforços no estímulo à prática da atividade físicaThis report describes the characteristics of physical activities pattern among adult population of Brazilian State Capitals and the Federal District in 2006. Data was collected through the surveillance system of risk and protection factors for chronic diseases by telephone inquiry (Vigitel) in a probabilistic sample of 54,369 individuals aged 18 years and older. We analyzed two indicators: leisure time physical activity; and sedentariness. The frequency of individuals active in leisure was just of 14.9%, greater among men. Walking is the most common modality for both sex. Frequency of leisure active life increases with education, and decreases with age. Sedentary life affects 29.2% of adult population, more frequently males. The physical activity profile is not satisfactory in all cities, which determines the need for more efforts to stimulate the practice of physical activit

Subcutaneous Adipose Tissue Plays A Beneficial Effect On Subclinical Atherosclerosis In Young Survivors Of Acute Lymphocytic Leukemia.

The aim of this study was to evaluate the relationship between body composition, metabolic profile, adipokines, and carotid intima-media thickness (cIMT) in young survivors of childhood acute lymphocytic leukemia (ALL). This cross-sectional study compared 55 ALL survivors, of chronological age between 15 years and 24 years, assigned into two groups according to the exposure to cranial radiation therapy (CRT; 25 irradiated and 30 nonirradiated) with 24 leukemia-free controls, and assessed body fat mass (dual-energy X-ray absorptiometry), computed tomography scan-derived abdominal adipose tissue, lipid profile, blood pressure (BP), adipokines, and cIMT by a multiple regression analysis. Treatment with CRT had an effect on all of the variables derived from the computed tomography scan: visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) (P<0.050). In a multiple linear regression model, cIMT positively correlated with exposure to CRT (P=0.029), diastolic BP (P=0.016), and leptin-to-adiponectin ratio (P=0.048), while negatively related to SAT (P=0.007). In young survivors of childhood ALL, CRT modified the distribution of fat and played a critical role in determining cIMT. Leptin-to-adiponectin ratio, a biomarker of abdominal obesity and metabolic syndrome, and diastolic BP also influenced cIMT, a marker of subclinical atherosclerosis. Nonetheless, adiposity-associated vascular disease might be attenuated by SAT. Changes in body fat must be evaluated in this group of patients in the early course of survivorship in order to avoid premature cardiovascular disease associated with atherosclerosis. Yet, further research as regards the possible protective effect of SAT on vascular disease is warranted.11479-48

The management and effectiveness of professionalization: An educational-based Epistemical study

This academic paper was developed with the aim of analyzing the management challenges for the effectiveness of professionalization. Managers of companies and educational units must contain all their demands in a unit in the administrative sector, so that there are no gaps or divisions in the separation of problems, such as lack of communication and difficulty in working as a team. Therefore, thinking about the actions of managers is immensely important for a good forwarding of professionalization. This is a bibliographical and documentary research, with a qualitative interpretive nature. With regard to the conditions for the effectiveness of the management process in the Brazilian business and educational fields, it became effective for us to carry out a bibliographic survey of existing studies on the subject since the turn of the 21st century. It is argued, therefore, that it is necessary to adopt a more professional and qualified management for the development and concreteness of the professional subject, as well as all those involved in the administrative system

Rest energy expenditure is decreased during the acute as compared to the recovery phase of sepsis in newborns

<p>Abstract</p> <p>Background</p> <p>Little is known with respect to the metabolic response and the requirements of infected newborns. Moreover, the nutritional needs and particularly the energy metabolism of newborns with sepsis are controversial matter. In this investigation we aimed to evaluate the rest energy expenditure (REE) of newborns with bacterial sepsis during the acute and the recovery phases.</p> <p>Methods</p> <p>We studied nineteen neonates (27.3 ± 17.2 days old) with bacterial sepsis during the acute phase and recovery of their illness. REE was determined by indirect calorimetry and VO₂and VCO₂measured by gas chromatography.</p> <p>Results</p> <p>REE significantly increased from 49.4 ± 13.1 kcal/kg/day during the acute to 68.3 ± 10.9 kcal/kg/day during recovery phase of sepsis (P < 0.01). Similarly, VO₂(7.4 ± 1.9 <it>vs </it>10 ± 1.5 ml/kg/min) and VCO₂(5.1 ± 1.7 <it>vs </it>7.4 ± 1.5 ml/kg/min) were also increased during the course of the disease (P < 0.01).</p> <p>Conclusion</p> <p>REE was increased during recovery compared to the sepsis phase. REE of septic newborns should be calculated on individualized basis, bearing in mind their metabolic capabilities.</p

Angiotensin Converting Enzyme Regulates Cell Proliferation and Migration

Background The angiotensin-I converting enzyme (ACE) plays a central role in the renin-angiotensin system, acting by converting the hormone angiotensin-I to the active peptide angiotensin-II (Ang-II). More recently, ACE was shown to act as a receptor for Ang-II, and its expression level was demonstrated to be higher in melanoma cells compared to their normal counterparts. However, the function that ACE plays as an Ang-II receptor in melanoma cells has not been defined yet. Aim Therefore, our aim was to examine the role of ACE in tumor cell proliferation and migration. Results We found that upon binding to ACE, Ang-II internalizes with a faster onset compared to the binding of Ang-II to its classical AT1 receptor. We also found that the complex Ang-II/ACE translocates to the nucleus, through a clathrin-mediated process, triggering a transient nuclear Ca2+ signal. In silico studies revealed a possible interaction site between ACE and phospholipase C (PLC), and experimental results in CHO cells, demonstrated that the beta 3 isoform of PLC is the one involved in the Ca2+ signals induced by Ang-II/ACE interaction. Further studies in melanoma cells (TM-5) showed that Ang-II induced cell proliferation through ACE activation, an event that could be inhibited either by ACE inhibitor (Lisinopril) or by the silencing of ACE. In addition, we found that stimulation of ACE by Ang-II caused the melanoma cells to migrate, at least in part due to decreased vinculin expression, a focal adhesion structural protein. Conclusion ACE activation regulates melanoma cell proliferation and migration.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)INCT Nanocarbono - UFMG (Brazil)Univ Fed Minas Gerais, Dept Physiol & Biophys, Belo Horizonte, MG, BrazilUniv Fed Sao Joao del Rei, Dept Nat Sci, Sao Joao Del Rei, MG, BrazilUniv Fed Ceara, Dept Phys, Fortaleza, CE, BrazilUniv Fed Sao Paulo, Dept Biophys, Sao Paulo, SP, BrazilUniv Fed Minas Gerais, Dept Phys, Belo Horizonte, MG, BrazilUniv Fed Minas Gerais, Dept Morphol, Belo Horizonte, MG, BrazilDepartment of Biophysics, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, BrazilWeb of Scienc

Modelagem da proteção do solo por plantas de cobertura no sul de Minas Gerais.

A cobertura do solo é o fator de maior importância relativa no controle da erosão hídrica. Assim, objetivou-se no presente estudo elaborar a modelagem da cobertura vegetal de vinte e quatro plantas de cobertura, em diversos sistemas de plantio e históricos de uso, com potencial para cultivo no Sul de Minas Gerais. Para avaliação da cobertura vegetal foram realizadas avaliações no campo utilizando uma régua de classificação da cobertura vegetal, sendo o delineamento experimental inteiramente casualizado, com três repetições, utilizado neste experimento. As plantas cultivadas sobre a palhada de feijão irrigado apresentaram alto índice de cobertura do solo, o que pode estar relacionado à maior disponibilidade de nutrientes deixado por esta cultura na palhada e a maior reserva de água no solo, promovido pela irrigação do feijão. O milheto cultivado em nível e sobre a palhada de milheto e feijão-de-porco apresentou o menor índice de cobertura entre as plantas testadas. Na região sul de Minas Gerais os padrões de chuvas ocorrem em maior quantidade nos períodos de outubro a março, com elevação em dezembro e janeiro. Neste período o solo deve estar protegido do impacto da gota de chuva, pois o risco de erosão hídrica é maior. Assim, a utilização das plantas de cobertura é de grande importância, pois estas protegem o solo do impacto direto das gotas de chuvas e diminuem os picos de temperatura do solo, sendo que estas devem ser cultivadas, preferencialmente, sobre a palhada de feijão

Sensor based on β - NiOx hybrid film/multi-walled carbon nanotubes composite electrode for groundwater salinization inspection

The enrichment of groundwater with different nutrients (Na+, Ca2+, Mg2+, Cl−, CO32−, among others) triggers the salinization of the aquifer and makes it inappropriate for many purposes. In this work, we developed a highly sensitive and selective electrochemical sensor, based on Ni-inorganic films electrosynthetized in situ onto multi-walled carbon nanotubes composite paste electrode (MWCNE), which allows the early detection of salinization. The working sensor (β-NiOx/MWCNE) was derivatized from nickel hexacyanoferrate modified electrode in strong alkaline medium (pH = 12), producing a hybrid film composed by β-Ni(OH)2 and β-NiO(OH). The electrochemical properties, morphology and chemical composition of the formed β-NiOx thin films were evaluated by voltammetry, scanning electron microscopy and X-ray spectroscopy. The developed β-NiOx/MWCNE sensor was highly sensitive to the presence of Na+ cation by ion-exchange, and the increase of Na+ concentration in the range 4.46 × 10−7 to 4.93 × 10−6 mol L−1 inhibited linearly the reversible electrochemical signal of the device, allowing to determine trace concentrations of this ion (LOD = 9.86 × 10−8 mol L−1) with high correlation coefficient of the data (r = 0.999) and suitable precision/reproducibility of the measurements (RSD < 9%). Using Na+ as salinization marker and β-NiOx/MWCNE as electroanalytical device, we found evidences of groundwater salinization in Grossos, a Brazil coast city, whose inhabitants have hypertension above the national average. The attained results were comparable to those obtained by the standard methods for Na+ analysis (percentage error ranging from 0.5 to 1.6%), confirming the accuracy of the proposed electroanalytical platform.info:eu-repo/semantics/publishedVersio