31 research outputs found
Geriatric in Patient Profile at the Department of Internal Medicine at Niamey National Hospital, Niger
Background: The ageing population in developing countries has brought a demographic and an epidemiological transition, with the impact of chronic diseases resulting from life style changes on the health status of the population. Objective: To describ a profile geriatrics patient, specifically to identify epidemiologic, clinical, etiologic and outcome of this group at the department of internal medicine to NNH Patients and method: Medical records of all geriatric patients aged â„65 years admitted at the department of NNH Between January 2012 and December 2015 were retrieved and reviewed retrospectively. Results: A total of 6074 admissions at the internal medicine department of NNH over three years were reported and 1130 (18, 6%) were geriatrics patients, the average age was 75, 95 years and more than half were men (50,7%). 80 % of patients were in the young old group (65-74 years), 13% in the old group (75-84 years) and 7% in the oldest old group (â„85 years). High blood pressure was the frequent comorbidity (12, 3%) and the most symptoms caused hospitalization were stroke (17, 6%), fevers (16, 5%) and worst health (13, 1%). Frequent illnesses were cardiovascular diseases (38.4%), infections, (19.2%) and endocrine diseases (11%). The average length of hospital stays was 8, 7 days. The mortality rate was 18, 2% and the worst outcomes factors were female sex, frail elderly group in 75 to 84 years and high blood pressure. Conclusion: Chronic diseases were responsible of morbidity and mortality for the majority elderlyâs patient
e-Pilly TROP Maladies infectieuses tropicales
Lâe-Pilly TROP est un ouvrage dâinfectiologie tropicale destinĂ© aux mĂ©decins et aux Ă©tudiants en mĂ©decine des pays francophones du Sud. La prise en compte des diffĂ©rents niveaux de la pyramide sanitaire dans ces pays le rend aussi accessible aux infirmiers des centres de santĂ© communautaires urbains et des structures de santĂ© intermĂ©diaires des zones rurales. Par dĂ©finition, les Pays En DĂ©veloppement accroissant progressivement leurs capacitĂ©s de diagnostic biologique et de traitement, les outils de prise en charge correspondent aux moyens des niveaux pĂ©riphĂ©riques comme Ă ceux des niveaux hospitaliers de rĂ©fĂ©rence
Efficacite et tolerance de lâassociation artemether lumefantrine dans le traitement du paludisme simple a Plasmodium falciparum au Niger
ProblĂ©matique : Le paludisme, de par son ampleur,sa gravitĂ© et ses consĂ©quences Ă©conomiques et sociales demeure un problĂšme de santĂ© publique majeur dans les pays tropicaux en gĂ©nĂ©ral et au Niger enparticulier. A ces consĂ©quences vient sâajouter la polychimiorĂ©sistance simultanĂ©e ou croisĂ©e des souches de P.falciparum aux antipaludiques courants. Pour y remĂ©dier le programme national de lutte contre lepaludisme du Niger a adoptĂ© lâassociation artĂ©mether lumĂ©fantrine (COARTEMÂź) en traitement de premiĂšre intention du paludisme simple en 2005. Nous avons Ă©valuĂ© lâefficacitĂ© thĂ©rapeutique et la tolĂ©rance de lâartĂ©mether lumĂ©fantrine chez les patients impaludĂ©s de moins de 5 ans au niveau des trois sites sentinelles du Niger.Objectif : Lâobjectif gĂ©nĂ©ral est dâĂ©tudier lâefficacitĂ© thĂ©rapeutique et la tolĂ©rance du COARTEMÂź chez les sujets souffrant de paludisme Ă Plasmodium falciparum non compliquĂ©.MĂ©thodologie : Câest une Ă©tude multicentrique, prospective, descriptive et ouverte avec un seul bras pour Ă©valuer lâefficacitĂ© thĂ©rapeutique et la tolĂ©rance de lâassociation artĂ©mether lumĂ©fantrine chez des enfantsde moins de 5 ans souffrant de paludisme simple au Niger. Le protocole OMS/2003 a Ă©tĂ© utilisĂ©.RĂ©sultats : 389 enfants ont Ă©tĂ© consultĂ©s, 202 enfants ont Ă©tĂ© suivis sur le plan clinique et parasitologique jusquâĂ J28 dont 84 Ă Gaya, 70 Ă Tessaoua et 48 Ă Agades. Au Niger, la rĂ©ponse clinique et parasitologique (RCPA) aprĂšs PCR, chez les enfants de moins de 5 ans est de 92%. Elle est de 96,3% Ă Tessaoua, 94.1% Ă Agades et 89,6% Ă Gaya. Il nâya pas de diffĂ©rence significative de rĂ©ponse entre les trois sites sentinelles (p>0,05). Avant la correction des donnĂ©es par PCR, la rĂ©ponse clinique et parasitologique adĂ©quate Ă©tait de 88.8%. Le COARTEM est bien tolĂ©rĂ©.Aucun effet secondaire indĂ©sirable nâa Ă©tĂ© observĂ© chez les sujets traitĂ©s.Conclusion : Le COARTEMÂź est une molĂ©cule efficace, qui rĂ©duit significativement la densitĂ© parasitaire et les manifestations cliniques du paludisme. Il peut ĂȘtre prescrit en traitement de premiĂšre intention du paludisme simple comme le recommande le MinistĂšre de la SantĂ© Publique du Niger (MSP/Niger). Le COARTEMÂź est une molĂ©cule qui est bien tolĂ©rĂ©e par les patients. Mots clĂ©s : RĂ©sistance, P.falciparum, ArtĂ©mether lumĂ©fantrine, Sites sentinelles et Niger. Efficacy and safety of artemether-lumefantrine in the treatment of uncomplicated malaria in Niger.Background: Malaria, with its width, its gravity and its economic and social consequences remains a major public health problem in tropical countries like Niger. These consequences come to be added the simultaneous or cross rĂ©sistance of P.falciparum to currents drugs. The National Malaria Programme of Niger adopted artemether-lumefantrine (COARTEMÂź) in treatment of uncomplicated malaria in 2005. We evaluated the efficacy and safety of artĂ©mether-lumĂ©fantrine in the treatment of children less than 5 years at Gaya, Tessaoua and Agades, three sentinelsâ sites of Niger.Objectives: The main objective of the study is to evaluate the efficacy and the safety of COARTEMÂź in the treatment of uncomplicated P.falciparum malaria in Niger.Methodology: It is a multicentric, prospective, descriptive and open study with only one arm to evaluate the efficacy and safety of artemether-lumefantrine in children less than 5 years suffering from uncomplicated malaria in Niger. OMS/2003 protocol was used.Results: 389 children were consulted and 199 children were followed for 28 days. 81 children are from Gaya, 70 from Tessaoua and 48 from Agades. After PCR, the clinical and parasitological adequate response (CPAR) of children less than 5 years is 92%. The CPAR is 96.3% at Tessaoua, 94.1% at Agades and 89.6% at Gaya. The difference of response between the three sentinels sites is not significant (p>0,05). Before PCR, the clinical and parasitological adequate response was 88.8%. The COARTEMÂź is welltolerated. No undesirable effect was observed during the study.Conclusion: COARTEMÂź is an effective drug, which reduces significantly parasitic and clinical symptoms of malaria. It can be prescribed in treatment of uncomplicated malaria as public health ministry of Niger recommends. COARTEMÂź is also safety and well tolerated by the patients.Key Words: Efficacy, Safety, Artemether-lumefantrine, P. falciparum, Niger
Traitement de la leishmaniose cutanee par le metronidazole : A propos de 78 cas au Niger
La leishmaniose cutanĂ©e sĂ©vit de façon endĂ©mique au Niger. Le premier cas a Ă©tĂ© rapportĂ©Â en 1911. Lâatteinte de la population rurale est prĂ©dominante. Les formes cliniques classiques Ă type de lĂ©sions ulcĂ©rocrouteuses, ulcĂ©reuses et nodulaires sont observĂ©es en nombre important et aux localisations diverses. Leishmania major est pratiquement lâagent pathogĂšne retrouvĂ© au Niger, pays situĂ© dans une bande comprise entre les 8° et 20° latitudes nord allant de lâAtlantique Ă la frontiĂšre tchadienne. La prise en charge avec le mĂ©tronidazole est spectaculaire mĂȘme dans des formes ayant rĂ©sistĂ© Ă lâantimoniate de mĂ©glumine. Soixante-dix-huit patients ont Ă©tĂ© traitĂ©s pendant huit (8) semaines et suivis pendant 1 an. Nous avons obtenu 100% de guĂ©rison. Le mĂ©tronidazole Ă lâĂ©tat actuel est la meilleure indication dans le traitement de la leishmaniose cutanĂ©e au Niger.Mots clĂ©s : Leishmaniose cutanĂ©e, mĂ©tronidazole, Niamey, Niger
Etude de lâimpact socio-Ă©conomique du diabĂšte Ă Niamey
Introduction: Le diabĂšte est un problĂšme majeur de santĂ© publique par sa prĂ©valence importante et croissante dâune part, et son impact socio-Ă©conomique dâautre part.MĂ©thodologie: Il sâagit dâune Ă©tude prospective de type transversal de Janvier 2013 Ă Septembre 2013, portant sur 152 patients vus en consultation ou hospitalisĂ©s Ă lâHĂŽpital National de Niamey (services de pĂŽles de cardiologie, de mĂ©decine interne, et des urgences mĂ©dicale et chirurgicale). Ont Ă©tĂ© inclus les patients admis dans les services citĂ©s ci-dessus, ĂągĂ©s dâau moins 15 ans, diabĂ©tiques connus pendant une durĂ©e supĂ©rieure Ă 1 an au moins.RĂ©sultats: Les femmes (58%) prĂ©dominent notre Ă©chantillon de 152 patients. lâAge moyenne a Ă©tĂ© de 53,82 ans (16 Ă 83 ans). Les patients rĂ©sidant Ă Niamey sont plus reprĂ©sentĂ©s. LâacidocĂ©tose est la complication aigue la plus retrouvĂ©e dans 65,85%, tandis que les complications chroniques sont dominĂ©es par les complications cardiovasculaires dans 29,10% et les pieds diabĂ©tiques dans 29,10%. Le coĂ»t direct de la prise en charge est reprĂ©sentĂ© par les frais mensuels des consultations, Examens complĂ©mentaires, mĂ©dicaments, dĂ©placement et hospitalisation a Ă©tĂ© de 23270,7 et 279298,2 annuellement.Les coĂ»ts indirects sont reprĂ©sentĂ©s par les absences rĂ©pĂ©tĂ©es au travail pour cause de maladie ou de visite mĂ©dicale, Lâinaptitude au travail, DĂ©part Ă la retraite anticipĂ©e pour cause dâinvaliditĂ©, absences au travail de lâentourage, Le dĂ©cĂšs prĂ©maturĂ© reprĂ©sentent respectivement 51,22% ; 23,2% ; 12,73% ; 8,55% ; 2%.Conclusion: le coĂ»t direct de la prise en charge du diabĂšte reste Ă©levĂ©, alors que le revenu des patients est trĂšs bas. Les coĂ»ts indirects sont responsables dâune perte de productivitĂ©. Le coĂ»t de cette perte de productivitĂ© peut ĂȘtre aussi Ă©levĂ©, voire plus, que celui des coĂ»ts directs.Mots clĂ©s: CoĂ»t, diabĂšte, NiameyEnglish Title: Study of the socio-economic impact of diabetesEnglish AbstractIntroduction: Diabetes is a major public health problem through its large and growing prevalence of hand, and its socio-economic impact on the other.Methodology: The survey forms have served us study materials. And we conducted a prospective, cross-sectional study from January 2013 to September 2013; covering 152 patients seen or admitted to the National Hospital of Niamey (service centers cardiology, internal medicine, and emergency medical and surgical). The inclusion criteria were: patients admitted to the services listed above, patients at least 15 years,  known for a period greater than one year at least diabetic patients who agreed to participate in the survey.Results: The women (58%) prevail our sample of 152 patients. The Age averages was of 53.82 years (16 - 83 years old). The patients living in Niamey are more represented. The acidocetose is the acute (sharp) complication the most found in 65.85%, whereas the chronic complications are dominated by the cardiovascular complications in 29.10% and feet diabetics in 29.10%. The direct cost of the coverage (care) is represented by the monthly expenses of the consultations, complementary (additional) Examinations, the medicine, the travel (movement) and hospitalization was 23270.7 and 279298.2 annually.The indirect costs are represented by the absences repeated to the work because of illness or of medical examination. The unemployability, Retirement anticipated because of incapacity, absences in the work of the circle of acquaintances, The premature death Represent respectively 51.22%; 23.2%; 12.73%; 8.55%; 2%.Conclusion: In our study, the direct cost of managing diabetes is high. Indeed, the annual health expenditure ranges between 50.000 to 300.000 FCFA, 69% of the sample and indirect costs are responsible for a loss of productivity. The cost of this lost productivity can be as high as or more than the direct costs.Keywords: Cost, diabetes, Niame
Maladie de hodgkin a propos de 40 cas colliges a lâhopital national de Niamey (HNN) au Niger.
Objectifs : Cette Ă©tude vise Ă dĂ©crire les caractĂ©ristiques Ă©pidĂ©miologiques, cliniques et paracliniques de la maladie de Hodgkin (MdH). Câest la premiĂšre Ă©tude nigĂ©rienne spĂ©cialement consacrĂ©e Ă cette maladie.Patients et mĂ©thodes : Il sâagit de patients suivis en service dâOnco-HĂ©matologie de lâHNN pour MdH pendant une pĂ©riode de 10 ans (janvier 2000 Ă dĂ©cembre 2009). Les donnĂ©es avaient Ă©tĂ© recueillies Ă partir des dossiers des malades.RĂ©sultats : Quarante (40) dossiers Ă©taient retenus pour lâĂ©tude. LâĂąge moyen Ă©tait de 25,4 ans et les extrĂȘmes entre 5 et 65 ans. Le sex ratio hommes/femmes Ă©tait de 3. Les adĂ©nopathies (ADP) superficielles constituaient le principal motif de consultation (97,50%). Les principales localisations des (ADP) Ă©taient cervicales (60%). Le signe clinique dâĂ©volutivitĂ© le plus frĂ©quent Ă©tait la fiĂšvre (65%). Les stades III et IV reprĂ©sentaient 62,97% des cas. Sur le plan biologique, la cytologie mettait en Ă©vidence la cellule de Reed Sternberg dans 90% des cas et Ă lâhistologie les types 3 et 4 reprĂ©sentaient 69% des cas (respectivement 38% et 31%). LâanĂ©mie Ă©tait retrouvĂ©e dans 57% et lâhyperleucocytose dans 29% des cas. La vitesse de sĂ©dimentation accĂ©lĂ©rĂ©e dans 93,75% des cas Ă©tait le signe biologique dâĂ©volutivitĂ© le plus frĂ©quent. La sĂ©rologie VIH Ă©tait positive dans 5,60% des cas. A lâimagerie, le scanner Ă©tait rĂ©alisĂ© chez seulement 1 patient. La radiographie pulmonaire standard avait montrĂ© des adĂ©nopathies mĂ©diastinales dans 75% des cas et lâĂ©chographie avait objectivĂ© la splĂ©nomĂ©galie et lâhĂ©patomĂ©galie respectivement dans 42,85%, et 38,09% des cas.Conclusion : La MdH est une hĂ©mopathie maligne rencontrĂ©e au Niger plus souvent chez lâhomme de jeune Ăąge. La principale manifestation Ă©tait les adĂ©nopathies cervicales. Le diagnostic Ă©tait souvent rĂ©alisĂ© Ă un stade avancĂ© de la maladie. Lâextension de la maladie est sous-estimĂ©e du fait de lâinsuffisance du plateau technique.Mots clĂ©s : Hodgkin, Cellule de Reed Sternberg, adĂ©nopathie, cytologie, Niamey.HODGKIN DESEASE: STUDY OF 40 CASES AT THE NATIONAL HOSPITAL OF NIAMEY IN NIGER. ABSTRACTPurpose: The study aims to describe the epidemiological, clinical, and para-clinical characteristics of Hodgkin disease (HD). It is the first kind of study conducted which especially targets this disease in Niger.Patients and method: It is about patients followed at the Onco-Hematology service of the National Hospital of Niamey. The study was spanned on 10 years from January 2000 to December 2009. The data were obtained from patient files.Results: The mean age of the patients was 25.4 years. Males predominate with a sex ratio of 3. The extremes were 5 and 65 years. Superficial adenopathies were the most frequent symptoms (97.5%). The main localizations were cervical (60%). The most frequent clinical evolution signs were fever (65%). Stages III and IV represented 62.77% of the cases. The cytological exam highlights the Reed Sternberg cell (72.5% of cases). The histological exam revealed that types 3 and 4 represented 69% of the cases. The anemia was found in 57% and the hyperleucocytosis with 29% of the cases. The speed of sedimentation was up in 93.75% of the patients. It was the main sign of biological evolution. The HIV serology was positive in 5.60% of patients. The scanner has been realized to one patient. The chest radiography showed that mediastinal adenopathies were the most frequent deep localizations (75%). The echography showed that the splenomegaly and the hepatomegaly represented respectively 42.85% and 39.09% of cases.Conclusion: The Hodgkin disease is most often found among young males in Niger. The main manifestation was cervical adenopathies. The diagnosis was often done at an advance stage of the disease. The scope of the disease was underestimated due to the shortage of technical equipment.Keywords: Hodgkin, Reed Sternberg Cell, adenopathy, cytology, Niamey
Maladie de lyme ou myopathie ?
PrĂ©-requis: Les atteintes musculaires atypiques dans la maladie de Lyme peuvent poser le problĂšme de lâimputabilitĂ© directe de la maladie de Lyme ou comme facteur dĂ©clenchant de la maladie musculaire mĂ©connue.But: Montrer la difficultĂ© du diagnostic diffĂ©rentiel entre les atteintes musculaires de la maladie de Lyme et certaines myopathiesObservation: Nous rapportons le cas clinique dâune patiente de 65 ans chez qui le diagnostic de la maladie de Lyme a Ă©tĂ© posĂ© avec une symptomatologie musculaire mimant une dystrophie facio-scapulo-humĂ©rale (FSH) ou une myosite inflammatoire.Conclusion: Cette observation soulĂšve lâintĂ©rĂȘt du traitement antibiotique prĂ©coce dĂ©s la phase de lâĂ©rythĂšme migrans mĂȘme avec une sĂ©rologie Lyme douteuse ou nĂ©gative.Mots clĂ©s: Lyme, amyotrophie, myosite, dystrophie scapulo-humĂ©raleEnglish Title: Lyme disease or myopathy?English AbstractBackground: Atypical myopathy in Lyme disease can pose the problem of the direct accountability of the disease or as a triggering factor of a unknown muscle disease.Aim: Show the difficulty of differential diagnosis between myopathy of Lyme disease and certain myopathies.Observation: We report the case of a 65 years old woman in whom the diagnosis of Lyme disease was made with muscular symptoms mimicking facial scapular-humeral dystrophy or myositis.Conclusion: This raises the need of early antibiotic treatment dice the erythema migrans phase even with insignificant or negative lyme serology.Keywords: Lyme, amyotrophy, myositis, facial-scapular-humeral