The cartujano stock of the spanish horse in America

The Cartujano stock of the Spanish horse is eumetric, mesomorphous, constitutionally compact and with subconvex profile. It shows a bright and energic aspect, with appreciable elevations and extensions. Its constitutional type is orthostenic or equanimous, its character is noble and docile. It is very interesting for the breaking in high school. This stock has its origin in the farm created by the Cartujanos monks from Jerez de la Frontera, in 1492. Today it can be find in Colombia on Mr. Francisco León Arboleda’s farm; in Costa Rica included in the farms of Mr. Mariano Guardia and Mr. Jorge Herrera, among others. Also in Cuba bought by Mr. Fidel Castro; in E.E.U.U. included in the farms of Mr. Currier, Mr. Broston, Mr. Parkinson, Mr. Garmendia and Mr. Alcalde, among others. In Mexico the most important breeders are Mr. Miguel Alemán, Mr. Enrique Alvarez and Mr. Plácido Arango. We also find this stock in other countries such as Nicaragua, Perú, Venezuela, etc. All that shows its important genetic contribution to the Spanish Breed horse in America.La estirpe Cartujana del Caballo Español es eumétrica, mesomorfa, constitucionalmente compacta y de perfil subconvexo. Esto le da un aspecto elegante y enérgico, con una apreciable elevación y extensión. Su tipo constitucional es ortosténico ó equilibrado, su carácter es noble y dócil. Es muy adecuada para la doma de Alta Escuela. Tiene su origen en la ganadería creada por los monjes Cartujanos de Jerez de la Frontera, en 1492. Se emplea aun como mejorante del caballo de raza española en Colombia (ganadería de D. Francisco León Arboleda) y en Costa Rica en las ganaderías del Sr. Mariano Guardia, D. Jorge Herrera y otras. También en Cuba fue comprada por el Sr. Fidel Castro; en USA se encuentra en las ganaderías de los sres. Currier, Broston, Parkinson, Garmendia, Alcalde, y otros. En México los ganaderos más importantes son D. Miguel Alemán, D. Enrique Alvarez y D. Plácido Arango. También está presente en Nicaragua, Perú, Venezuela, etc. Lo que demuestra su importante aportación genética al caballo Español en América

The redshift and broad band spectral energy distribution of NRAO 150

Context. NRAO 150 is one of the brightest radio and mm AGN sources on the northern sky. It has been revealed as an interesting source where to study extreme relativistic jet phenomena. However, its cosmological distance has not been reported so far, because of its optical faintness produced by strong Galactic extinction. Aims. Aiming at measuring the redshift of NRAO 150, and hence to start making possible quantitative studies from the source. Methods. We have conducted spectroscopic and photometric observations of the source in the near-IR, as well as in the optical. Results. All such observations have been successful in detecting the source. The near-IR spectroscopic observations reveal strong H$\alpha$ and H$\beta$ emission lines from which the cosmological redshift of NRAO 150 ($z=1.517\pm0.002$) has been determined for the first time. We classify the source as a flat-spectrum radio-loud quasar, for which we estimate a large super-massive black-hole mass $\sim5\times 10^{9} \mathrm{M_\odot}$. After extinction correction, the new near-IR and optical data have revealed a high-luminosity continuum-emission excess in the optical (peaking at $\sim2000$\,\AA, rest frame) that we attribute to thermal emission from the accretion disk for which we estimate a high accretion rate, $\sim30$\,% of the Eddington limit. Conclusions. Comparison of these source properties, and its broad-band spectral-energy distribution, with those of Fermi blazars allow us to predict that NRAO 150 is among the most powerful blazars, and hence a high luminosity -although not detected yet- $\gamma$-ray emitter.Comment: 8 pages, 4 figure

Electromagnetic multipole moments of elementary spin-1/2, 1, and 3/2 particles

We study multipole decompositions of the electromagnetic currents of spin-1/2, 1, and 3/2 particles described in terms of Lagrangians designed to reproduce representation specific wave equations which are second order in the momenta and which emerge within the recently elaborated Poincar\'e covariant projector method. We calculate the electric multipoles of the above spins for the spinor, the four-vector, and the four-vector--spinor representations, attend to the most general non-Lagrangian spin-3/2 currents which are allowed by Lorentz invariance to be of third order in the momenta and construct the linear current equivalent of identical multipole moments of one of them. We conclude that such non-Lagrangian currents are not necessarily more general than the two-term currents emerging within the covariant projector method. We compare our results with those of the conventional Proca-, and Rarita-Schwinger frameworks. Finally, we test the representation dependence of the multipoles by placing spin-1 and spin-3/2 in the respective (1,0)$\oplus$(0,1), and (3/2,0)$\oplus$(0,3/2) single-spin representations. We observe representation independence of the charge monopoles and the magnetic dipoles, in contrast to the higher multipoles, which turn out to be representation dependent. In particular, we find the bi-vector $(1,0)\oplus (0,1)$ to be characterized by an electric quadrupole moment of opposite sign to the one found in $(1/2,1/2)$, and consequently, to the $W$ boson. Our finding points toward the possibility that the $\rho$ meson could transform as part of an antisymmetric tensor with an $a_{1}$ meson-like state as its representation companion.Comment: 27 pages, 2 figure

Dementia research in the Caribbean Hispanic islands: Present findings and future trends

During the last decade, the Caribbean Hispanic islands experienced accelerated demographic aging, representing the fastest aging region within Latin America. Age-related non-communicable diseases, including dementia, are now reported at high prevalence. The Caribbean islands share similar genetic ancestry, culture, migration patterns, and risk profiles, providing a unique setting to understand dementia in the Caribbean-Hispanics. This perspective article aimed to describe the impact of dementia in the Caribbean, at a local and regional level and reflect on research strategies to address dementia. We report on 10/66 project findings, described research projects and regional plans for the region. According to our results, the prevalence of dementia in the Caribbean is the highest in Latin America, with 11.7% in Dominican Republic, 11.6% in Puerto Rico, and 10.8% in Cuba. Preliminary data from new waves of the 10/66 study shows increasing numbers of dementia cases. Furthermore, dementia is expected to be one of the most serious medical and social issues confronted by Caribbean health systems. However, there is a scarcity of knowledge, awareness, and health services to deal with this public health crisis. In light of the new evidence, local and regional strategies are underway to better understand dementia trends for the region and develop policies aimed to decrease the impact of dementia. Implementation of our national plans is critical to deal with an aging population with high dementia rates. Current recommendations include emphasizing public health prevention campaigns to address modifiable risk factors and expand support to caregiver and family interventions

Autoimmune neurological conditions associated with Zika virus infection

Zika virus (ZIKV) is an emerging flavivirus rapidly spreading throughout the tropical Americas. mosquitoes is the principal way of transmission of the virus to humans. ZIKV can be spread by transplacental, perinatal, and body fluids. ZIKV infection is often asymptomatic and those with symptoms present minor illness after 3 to 12 days of incubation, characterized by a mild and self-limiting disease with low-grade fever, conjunctivitis, widespread pruritic maculopapular rash, arthralgia and myalgia. ZIKV has been linked to a number of central and peripheral nervous system injuries such as Guillain-Barré syndrome (GBS), transverse myelitis (TM), meningoencephalitis, ophthalmological manifestations, and other neurological complications. Nevertheless, mechanisms of host-pathogen neuro-immune interactions remain incompletely elucidated. This review provides a critical discussion about the possible mechanisms underlying the development of autoimmune neurological conditions associated with Zika virus infection

Costos de la otitis media aguda en niños de una ciudad de la costa caribe colombiana

Acute otitis media is the main cause of consultation, antibiotic use, and ambulatory surgery in developed countries; besides, it is associated with an important economic burden. However, non-medical indirect costs of acute otitis media, which are relevant in this pathology, have been underestimatedLa otitis media aguda es la principal causa de consultas médicas, de uso de antibióticos y de cirugías ambulatorias en los países desarrollados. Está asociada con una significativa carga económica, pero sus costos indirectos no médicos, los cuales son relevantes en esta enfermedad, se han subestimad

Expression of Novel Opsins and Intrinsic Light Responses in the Mammalian Retinal Ganglion Cell Line RGC-5. Presence of OPN5 in the Rat Retina

The vertebrate retina is known to contain three classes of photoreceptor cells: cones and rods responsible for vision, and intrinsically photoresponsive retinal ganglion cells (RGCs) involved in diverse non-visual functions such as photic entrainment of daily rhythms and pupillary light responses. In this paper we investigated the potential intrinsic photoresponsiveness of the rat RGC line, RGC-5, by testing for the presence of visual and non-visual opsins and assessing expression of the immediate-early gene protein c-Fos and changes in intracellular Ca2+mobilization in response to brief light pulses. Cultured RGC-5 cells express a number of photopigment mRNAs such as retinal G protein coupled receptor (RGR), encephalopsin/panopsin (Opn3), neuropsin (Opn5) and cone opsin (Opn1mw) but not melanopsin (Opn4) or rhodopsin. Opn5 immunoreactivity was observed in RGC-5 cells and in the inner retina of rat, mainly localized in the ganglion cell layer (GCL). Furthermore, white light pulses of different intensities and durations elicited changes both in intracellular Ca2+ levels and in the induction of c-Fos protein in RGC-5 cell cultures. The results demonstrate that RGC-5 cells expressing diverse putative functional photopigments display intrinsic photosensitivity which accounts for the photic induction of c-Fos protein and changes in intracellular Ca2+ mobilization. The presence of Opn5 in the GCL of the rat retina suggests the existence of a novel type of photoreceptor cell

Vimentin and heat shock protein expression are induced in the kidney by angiotensin and by nitric oxide inhibition

Vimentin and heat shock protein expression are induced in the kidney by angiotensin and by nitric oxide inhibition.BackgroundAngiotensin II (Ang II) infusion and nitric oxide synthesis (NOS) inhibition with Nω-nitro-L-arginine-methyl-ester (L-NAME) are experimental models of hypertension associated with renal inflammation and oxidative stress. To gain insight into the nature of the tubulointerstitial injury induced in these models, we studied lectin-binding specificities, vimentin expression, and heat shock protein (HSP) 60 and 70 in these experimental models.MethodsSprague-Dawley rats received Ang II infusion (435 ng/kg/min) for 2 weeks by subcutaneous minipumps (Ang II group, N = 5) or L-NAME in the drinking water (70 mg/100 mL) for 3 weeks (L-NAME group N = 7). The control group consisted of 10 rats. Systolic blood pressure (tail-cuff plethysmography), serum creatinine, and proteinuria were determined weekly. At the end of the treatment period, rats were sacrificed and kidneys studied. Binding specificities of fluorescein-labeled lectins were examined in frozen sections, and cellular infiltrates were identified by immunohistology and expression of vimentin and HSP 60 and 70 with immunohistochemistry and computer image analysis.ResultsTubulointerstitial accumulation of macrophages, lymphocytes, and Ang II–positive cells were present in the Ang II group and L-NAME group. Vimentin, HSP 60, and HSP 70 were increased 8 to 20 times in the cortex of the rats of the Ang II group and the L-NAME groups. Neoexpression of vimentin and HSPs was found primarily in proximal tubular cells.ConclusionAng II infusion and NOS inhibition induce tubular injury with epithelial cell transdifferentiation and expression of stress proteins. The role of these changes in the accumulation and activation of the interstitial inflammatory infiltrate merits further investigation