Split-Stirling-cycle displacer linear-electric drive

The retrofit of a 1/4-W split-Stirling cooler with a linear driven on the displacer was achieved and its performance characterized. The objective of this work was to demonstrate that a small linear motor could be designed to meet the existing envelope specifications of the cooler and that an electric linear drive on the displacer could improve the cooler's reliability and performance. The paper describes the characteristics of this motor and presents cooler test results

Sun protective behaviour and sunburn prevalence in primary and secondary schoolchildren in Western Switzerland

Abstract Background: Switzerland has one of the highest incidence of cutaneous malignant melanoma, a potentially preventable cancer since its main risk factor, exposure to ultraviolet (UV) radiation, is amenable to behavioural changes. Although solar over-exposure during childhood and adolescence increase the risk of melanoma, determinants of sunburn and sun protective behaviours of Swiss children have scarcely been explored. Objectives: To investigate sunburn occurrence and sun protective behaviours of schoolchildren in western Switzerland. Methods: Self-reported questionnaires were administered during regular classes to pupils of the 5th (primary school, n=431), 8th and 11th grades (secondary school, n=837) in the 18 public schools of la Chaux-de-Fonds, western Switzerland, regarding their sunburn occurrence and sun-related behaviours. Descriptive statistics and multivariate logistic regression analyses were performed to assess predictors of sunburns and of three sun protective behaviours (sunscreen, shade, wear of covering clothes). Results: Response rate was 91%. Sunburn prevalence over the preceding year was high (60% at least one sunburn, 30% at least two, 43% at least one painful or blistering sunburn). Younger age, fair skin, regular sunscreen use, higher sun-related knowledge and preference for a tanned skin were predictors of sunburn. Sunscreen was the most used protective measure (69%), followed by seeking shade (33%) and wearing long sleeves shirts (32%). Decline in all protective measures was observed in older and pro-tan attitudes pupils. The wear of covering clothes was significantly associated with sunscreen use and seeking shade. Parental encouragement favoured sunscreen use and wear of protective clothes. Conclusion: In future sun protection campaigns targeting children and adolescents, sunscreen use as last protective barrier against UV radiation should be better emphasized. Multi-faceted interventions, including role models, parents and peers should help to improve children sun- protective behaviours

Systematic search for high-energy gamma-ray emission from bow shocks of runaway stars

Context. It has been suggested that the bow shocks of runaway stars are sources of high-energy gamma rays (E > 100 MeV). Theoretical models predicting high-energy gamma-ray emission from these sources were followed by the first detection of non-thermal radio emission from the bow shock of BD+43^\deg 3654 and non-thermal X-ray emission from the bow shock of AE Aurigae. Aims. We perform the first systematic search for MeV and GeV emission from 27 bow shocks of runaway stars using data collected by the Large Area Telescope (LAT) onboard the Fermi Gamma-ray Space Telescope (Fermi). Methods. We analysed 57 months of Fermi-LAT data at the positions of 27 bow shocks of runaway stars extracted from the Extensive stellar BOw Shock Survey catalogue (E-BOSS). A likelihood analysis was performed to search for gamma-ray emission that is not compatible with diffuse background or emission from neighbouring sources and that could be associated with the bow shocks. Results. None of the bow shock candidates is detected significantly in the Fermi-LAT energy range. We therefore present upper limits on the high-energy emission in the energy range from 100 MeV to 300 GeV for 27 bow shocks of runaway stars in four energy bands. For the three cases where models of the high-energy emission are published we compare our upper limits to the modelled spectra. Our limits exclude the model predictions for Zeta Ophiuchi by a factor $\approx$ 5.Comment: 5 pages, 5 figures, 1 table, accepted by A&

Gravitational Collapse in One Dimension

We simulate the evolution of one-dimensional gravitating collisionless systems from non- equilibrium initial conditions, similar to the conditions that lead to the formation of dark- matter halos in three dimensions. As in the case of 3D halo formation we find that initially cold, nearly homogeneous particle distributions collapse to approach a final equilibrium state with a universal density profile. At small radii, this attractor exhibits a power-law behavior in density, {\rho}(x) \propto |x|^(-{\gamma}_crit), {\gamma}_crit \simeq 0.47, slightly but significantly shallower than the value {\gamma} = 1/2 suggested previously. This state develops from the initial conditions through a process of phase mixing and violent relaxation. This process preserves the energy ranks of particles. By warming the initial conditions, we illustrate a cross-over from this power-law final state to a final state containing a homogeneous core. We further show that inhomogeneous but cold power-law initial conditions, with initial exponent {\gamma}_i > {\gamma}_crit, do not evolve toward the attractor but reach a final state that retains their original power-law behavior in the interior of the profile, indicating a bifurcation in the final state as a function of the initial exponent. Our results rely on a high-fidelity event-driven simulation technique.Comment: 14 Pages, 13 Figures. Submitted to MNRA

The Phenion (R) Full-Thickness Skin Model for Percutaneous Absorption Testing

In recent years many efforts have been made to replace dermal toxicity testing of chemicals in the animal by in vitro assays. As a member of a German research consortium, we have previously contributed to the validation of an in vitro test protocol for percutaneous absorption studies on the basis of reconstructed human epidermis and both human and pig skin ex vivo. Aiming to assess the barrier properties of a newly developed reconstructed skin model, this protocol has now been transferred to the Phenion (R) Full-Thickness Skin Model (FT model). The permeation of testosterone and caffeine was quantified in parallel to that of pig skin using Franz-type diffusion cells. In addition, the permeation of benzoic acid and nicotine was studied. As expected, the FT model is more permeable than pig skin, yet its barrier properties are well in accordance with those of reconstructed human epidermis when compared to previous data. In fact, the FT model most efficiently retards testosterone as the compound of highest lipophilicity, which can be explained by an additional uptake by a reservoir formed by the dermis equivalent. Thus, the structure closely parallels human skin. In consequence, the Phenion FT model appears to be suitable for percutaneous absorption studies in hazard analysis and should be subjected to a catch-up validation study. Copyright (C) 2009 S. Karger AG, Base

On Existence and Properties of Approximate Pure Nash Equilibria in Bandwidth Allocation Games

In \emph{bandwidth allocation games} (BAGs), the strategy of a player consists of various demands on different resources. The player's utility is at most the sum of these demands, provided they are fully satisfied. Every resource has a limited capacity and if it is exceeded by the total demand, it has to be split between the players. Since these games generally do not have pure Nash equilibria, we consider approximate pure Nash equilibria, in which no player can improve her utility by more than some fixed factor $\alpha$ through unilateral strategy changes. There is a threshold $\alpha_\delta$ (where $\delta$ is a parameter that limits the demand of each player on a specific resource) such that $\alpha$-approximate pure Nash equilibria always exist for $\alpha \geq \alpha_\delta$, but not for $\alpha < \alpha_\delta$. We give both upper and lower bounds on this threshold $\alpha_\delta$ and show that the corresponding decision problem is ${\sf NP}$-hard. We also show that the $\alpha$-approximate price of anarchy for BAGs is $\alpha+1$. For a restricted version of the game, where demands of players only differ slightly from each other (e.g. symmetric games), we show that approximate Nash equilibria can be reached (and thus also be computed) in polynomial time using the best-response dynamic. Finally, we show that a broader class of utility-maximization games (which includes BAGs) converges quickly towards states whose social welfare is close to the optimum

An adaptive-binning method for generating constant-uncertainty/constant-significance light curves with Fermi-LAT data

We present a method enabling the creation of constant-uncertainty/constant-significance light curves with the data of the Fermi-Large Area Telescope (LAT). The adaptive-binning method enables more information to be encapsulated within the light curve than with the fixed-binning method. Although primarily developed for blazar studies, it can be applied to any sources. This method allows the starting and ending times of each interval to be calculated in a simple and quick way during a first step. The reported mean flux and spectral index (assuming the spectrum is a power-law distribution) in the interval are calculated via the standard LAT analysis during a second step. The absence of major caveats associated with this method has been established by means of Monte-Carlo simulations. We present the performance of this method in determining duty cycles as well as power-density spectra relative to the traditional fixed-binning method.Comment: 17 pages, 13 figures, 5 tables. Submitted to A&