H2 molecule in strong magnetic fields

The Pauli-Hamiltonian of a molecule with fixed nuclei in a strong constant magnetic field is asymptotic, in norm-resolvent sense, to an effective Hamiltonian which has the form of a multi-particle Schr\"odinger operator with interactions given by one-dimensional \delta-potentials. We study this effective Hamiltonian in the case of the H2 -molecule and establish existence of the ground state. We also show that the inter-nuclear equilibrium distance tends to 0 as the field-strength tends to infinity

454-Pyrosequencing: A Molecular Battiscope for Freshwater Viral Ecology

Viruses, the most abundant biological entities on the planet, are capable of infecting organisms from all three branches of life, although the majority infect bacteria where the greatest degree of cellular diversity lies. However, the characterization and assessment of viral diversity in natural environments is only beginning to become a possibility. Through the development of a novel technique for the harvest of viral DNA and the application of 454 pyrosequencing, a snapshot of the diversity of the DNA viruses harvested from a standing pond on a cattle farm has been obtained. A high abundance of viral genotypes (785) were present within the virome. The absolute numbers of lambdoid and Shiga toxin (Stx) encoding phages detected suggested that the depth of sequencing had enabled recovery of only ca. 8% of the total virus population, numbers that agreed within less than an order of magnitude with predictions made by rarefaction analysis. The most abundant viral genotypes in the pond were bacteriophages (93.7%). The predominant viral genotypes infecting higher life forms found in association with the farm were pathogens that cause disease in cattle and humans, e.g. members of the Herpesviridae. The techniques and analysis described here provide a fresh approach to the monitoring of viral populations in the aquatic environment, with the potential to become integral to the development of risk analysis tools for monitoring the dissemination of viral agents of animal, plant and human diseases

From AMANDA to IceCube

The first string of the neoteric high energy neutrino telescope IceCube successfully began operating in January 2005. It is anticipated that upon completion the new detector will vastly increase the sensitivity and extend the reach of AMANDA to higher energies. A discussion of the IceCube's discovery potential for extra-terrestrial neutrinos, together with the prospects of new physics derived from the ongoing AMANDA research will be the focus of this paper. Preliminary results of the first antarctic high energy neutrino telescope AMANDA searching in the muon neutrino channel for localized and diffuse excess of extra-terrestrial neutrinos will be reviewed using data collected between 2000 and 2003. Neutrino flux limits obtained with the all-flavor dedicated UHE and cascade analyses will be described. A first neutrino spectrum above one TeV in agreement with atmospheric neutrino flux expectations and no extra-terrestrial contribution will be presented, followed by a discussion of a limit for neutralino CDM candidates annihilating in the center of the Sun.Comment: 15 pages, 8 figures Invited talk contribution at 5th International Conference on Non-accelerator New Physics (NANP 05), Dubna, Russia, 20-25 Jun 200

Gamma Ray Bursts: recent results and connections to very high energy Cosmic Rays and Neutrinos

Gamma-ray bursts are the most concentrated explosions in the Universe. They have been detected electromagnetically at energies up to tens of GeV, and it is suspected that they could be active at least up to TeV energies. It is also speculated that they could emit cosmic rays and neutrinos at energies reaching up to the $10^{18}-10^{20}$ eV range. Here we review the recent developments in the photon phenomenology in the light of \swift and \fermi satellite observations, as well as recent IceCube upper limits on their neutrino luminosity. We discuss some of the theoretical models developed to explain these observations and their possible contribution to a very high energy cosmic ray and neutrino background.Comment: 12 pages, 7 figures. Text of a plenary lecture at the PASCOS 12 conference, Merida, Yucatan, Mexico, June 2012; to appear in J.Phys. (Conf. Series

Syk tyrosine kinase is critical for B cell antibody responses and memory B cell survival

Signals from the BCR are required for Ag-specific B cell recruitment into the immune response. Binding of Ag to the BCR induces phosphorylation of immune receptor tyrosine-based activation motifs in the cytoplasmic domains of the CD79a and CD79b signaling subunits, which subsequently bind and activate the Syk protein tyrosine kinase. Earlier work with the DT40 chicken B cell leukemia cell line showed that Syk was required to transduce BCR signals to proximal activation events, suggesting that Syk also plays an important role in the activation and differentiation of primary B cells during an immune response. In this study, we show that Syk-deficient primary mouse B cells have a severe defect in BCR-induced activation, proliferation, and survival. Furthermore, we demonstrate that Syk is required for both T-dependent and T-independent Ab responses, and that this requirement is B cell intrinsic. In the absence of Syk, Ag fails to induce differentiation of naive B cells into germinal center B cells and plasma cells. Finally, we show that the survival of existing memory B cells is dependent on Syk. These experiments demonstrate that Syk plays a critical role in multiple aspects of B cell Ab responses

Matching Dynamics with Constraints

We study uncoordinated matching markets with additional local constraints that capture, e.g., restricted information, visibility, or externalities in markets. Each agent is a node in a fixed matching network and strives to be matched to another agent. Each agent has a complete preference list over all other agents it can be matched with. However, depending on the constraints and the current state of the game, not all possible partners are available for matching at all times. For correlated preferences, we propose and study a general class of hedonic coalition formation games that we call coalition formation games with constraints. This class includes and extends many recently studied variants of stable matching, such as locally stable matching, socially stable matching, or friendship matching. Perhaps surprisingly, we show that all these variants are encompassed in a class of "consistent" instances that always allow a polynomial improvement sequence to a stable state. In addition, we show that for consistent instances there always exists a polynomial sequence to every reachable state. Our characterization is tight in the sense that we provide exponential lower bounds when each of the requirements for consistency is violated. We also analyze matching with uncorrelated preferences, where we obtain a larger variety of results. While socially stable matching always allows a polynomial sequence to a stable state, for other classes different additional assumptions are sufficient to guarantee the same results. For the problem of reaching a given stable state, we show NP-hardness in almost all considered classes of matching games.Comment: Conference Version in WINE 201

Direct photons in d+Au collisions at s_(NN)**(1/2)=200GeV with STAR

Results are presented of an ongoing analysis of direct photon production in s_(NN)=200GeV deuteron-gold collisions with the STAR experiment at RHIC. A significant excess of direct photons is observed near mid-rapidity 0<y<1 and found to be consistent with next-to-leading order pQCD calculations including the contribution from fragmentation photons.Comment: 4 pages, 4 figures, HotQuarks 200

Rhythm in the speech of a person with right hemisphere damage: Applying the pairwise variability index

Although several aspects of prosody have been studied in speakers with right hemisphere damage (RHD), rhythm remains largely uninvestigated. This study compares the rhythm of an Australian English speaker with right hemisphere damage (due to a stroke, but with no concomitant dysarthria) to that of a neurologically unimpaired individual. The speakers' rhythm is compared using the pairwise variability index (PVI) which allows for an acoustic characterization of rhythm by comparing the duration of successive vocalic and intervocalic intervals. A sample of speech from a structured interview between a speech and language therapist and each participant was analysed. Previous research has shown that speakers with RHD may have difficulties with intonation production, and therefore it was hypothesized that there may also be rhythmic disturbance. Results show that the neurologically normal control uses a similar rhythm to that reported for British English (there are no previous studies available for Australian English), whilst the speaker with RHD produces speech with a less strongly stress-timed rhythm. This finding was statistically significant for the intervocalic intervals measured (t(8) = 4.7, p < .01), and suggests that some aspects of prosody may be right lateralized for this speaker. The findings are discussed in relation to previous findings of dysprosody in RHD populations, and in relation to syllable-timed speech of people with other neurological conditions