PYRAMIR: Calibration and operation of a pyramid near-infrared wavefront sensor

The concept of pyramid wavefront sensors (PWFS) has been around about a decade by now. However, there is still a great lack of characterizing measurements that allow the best operation of such a system under real life conditions at an astronomical telescope. In this article we, therefore, investigate the behavior and robustness of the pyramid infrared wavefront sensor PYRAMIR mounted at the 3.5 m telescope at the Calar Alto Observatory under the influence of different error sources both intrinsic to the sensor, and arising in the preceding optical system. The intrinsic errors include diffraction effects on the pyramid edges and detector read out noise. The external imperfections consist of a Gaussian profile in the intensity distribution in the pupil plane during calibration, the effect of an optically resolved reference source, and noncommon-path aberrations. We investigated the effect of three differently sized reference sources on the calibration of the PWFS. For the noncommon-path aberrations the quality of the response of the system is quantified in terms of modal cross talk and aliasing. We investigate the special behavior of the system regarding tip-tilt control. From our measurements we derive the method to optimize the calibration procedure and the setup of a PWFS adaptive optics (AO) system. We also calculate the total wavefront error arising from aliasing, modal cross talk, measurement error, and fitting error in order to optimize the number of calibrated modes for on-sky operations. These measurements result in a prediction of on-sky performance for various conditions

Pedestrian Detection in Crowded Environments through Bayesian Prediction of Sequential Probability Matrices

In order to safely navigate populated environments, an autonomous vehicle must be able to detect human shapes using its sensory systems, so that it can properly avoid a collision. In this paper, we introduce a Bayesian approach to the Viola-Jones algorithm, as a method to automatically detect pedestrians in image sequences. We present a probabilistic interpretation of the basic execution of the original tool and develop a technique to produce approximate convolutions of probability matrices with multiple local maxima

CAFE: Calar Alto Fiber-fed Echelle spectrograph

We present here CAFE, the Calar Alto Fiber-fed Echelle spectrograph, a new instrument built at the Centro Astronomico Hispano Alem\'an (CAHA). CAFE is a single fiber, high-resolution ($R\sim$70000) spectrograph, covering the wavelength range between 3650-9800\AA. It was built on the basis of the common design for Echelle spectrographs. Its main aim is to measure radial velocities of stellar objects up to $V\sim$13-14 mag with a precision as good as a few tens of $m s^{-1}$. To achieve this goal the design was simplified at maximum, removing all possible movable components, the central wavelength is fixed, so the wavelentgth coverage; no filter wheel, one slit and so on, with a particular care taken in the thermal and mechanical stability. The instrument is fully operational and publically accessible at the 2.2m telescope of the Calar Alto Observatory. In this article we describe (i) the design, summarizing its manufacturing phase; (ii) characterize the main properties of the instrument; (iii) describe the reduction pipeline; and (iv) show the results from the first light and commissioning runs. The preliminar results indicate that the instrument fulfill the specifications and it can achieve the foreseen goals. In particular, they show that the instrument is more efficient than anticipated, reaching a $S/N\sim$20 for a stellar object as faint as $V\sim$14.5 mag in $\sim$2700s integration time. The instrument is a wonderful machine for exoplanetary research (by studying large samples of possible systems cotaining massive planets), galactic dynamics (high precise radial velocities in moving groups or stellar associations) or astrochemistry.Comment: 12 pages, 23 figures; Acepted for publishing in A&A, 201

Systematic review of the methods of health economic models assessing antipsychotic medication for schizophrenia

Background Numerous economic models have assessed the cost-effectiveness of antipsychotic medications in schizophrenia. It is important to understand what key impacts of antipsychotic medications were considered in the existing models and limitations of existing models in order to inform the development of future models. Objectives This systematic review aims to identify which clinical benefits, clinical harms, costs and cost savings of antipsychotic medication have been considered by existing models, to assess quality of existing models and to suggest good practice recommendations for future economic models of antipsychotic medications. Methods An electronic search was performed on multiple databases (MEDLINE, EMBASE, PsycInfo, Cochrane database of systematic reviews, The NHS Economic Evaluation Database and Health Technology Assessment database) to identify economic models of schizophrenia published between 2005–2020. Two independent reviewers selected studies for inclusion. Study quality was assessed using the National Institute for Health and Care Excellence (NICE) checklist and the Cooper hierarchy. Key impacts of antipsychotic medications considered by exiting models were descriptively summarised. Results Sixty models were included. Existing models varied greatly in key impacts of antipsychotic medication included in the model, especially in clinical outcomes used for assessing reduction in psychotic symptoms and types of adverse events considered in the model. Quality of existing models was generally low due to failure to capture the health and cost impact of adverse events of antipsychotic medications and input data not obtained from best available source. Good practices for modelling antipsychotic medications are suggested. Discussions This review highlights inconsistency in key impacts considered by different models, and limitations of the existing models. Recommendations on future research are provided

No variations in transit times for Qatar-1 b

The transiting hot Jupiter planet Qatar-1 b was presented to exhibit variations in transit times that could be of perturbative nature. A hot Jupiter with a planetary companion on a nearby orbit would constitute an unprecedented planetary configuration, important for theories of formation and evolution of planetary systems. We performed a photometric follow-up campaign to confirm or refute transit timing variations. We extend the baseline of transit observations by acquiring 18 new transit light curves acquired with 0.6-2.0 m telescopes. These photometric time series, together with data available in the literature, were analyzed in a homogenous way to derive reliable transit parameters and their uncertainties. We show that the dataset of transit times is consistent with a linear ephemeris leaving no hint for any periodic variations with a range of 1 min. We find no compelling evidence for the existence of a close-in planetary companion to Qatar-1 b. This finding is in line with a paradigm that hot Jupiters are not components of compact multi-planetary systems. Based on dynamical simulations, we place tighter constraints on a mass of any fictitious nearby planet in the system. Furthermore, new transit light curves allowed us to redetermine system parameters with the precision better than that reported in previous studies. Our values generally agree with previous determinations.Comment: Accepted for publication in A&

An All Sky Transmission Monitor: ASTMON

We present here the All Sky Transmission MONitor (ASTMON), designed to perform a continuous monitoring of the surface brightness of the complete night-sky in several bands. The data acquired are used to derive, in addition, a subsequent map of the multiband atmospheric extinction at any location in the sky, and a map of the cloud coverage. The instrument has been manufactured to afford extreme weather conditions, and remain operative. Designed to be fully robotic, it is ideal to be installed outdoors, as a permanent monitoring station. The preliminary results based on two of the currently operative units (at Do\~nana National Park - Huelva- and at the Calar Alto Observatory - Almer\'ia -, in Spain), are presented here. The parameters derived using ASTMON are in good agreement with previously reported ones, what illustrates the validity of the design and the accuracy of the manufacturing. The information provided by this instrument will be presented in forthcoming articles, once we have accumulated a statistically amount of data.Comment: 12 Figures, Accepted for publishing in PAS

Bacterial Contamination on Household Toys and Association with Water, Sanitation and Hygiene Conditions in Honduras

There is growing evidence that household water treatment interventions improve microbiological water quality and reduce diarrheal disease risk. Few studies have examined, however, the impact of water treatment interventions on household-level hygiene and sanitation. This study examined the association of four water and sanitation conditions (access to latrines, improved sanitation, improved water and the plastic biosand filter) on the levels of total coliforms and E. coli on existing and introduced toys during an on-going randomized controlled trial of the plastic biosand filter (plastic BSF). The following conditions were associated with decreased bacterial contamination on children’s toys: access to a latrine, access to improved sanitation and access to the plastic BSF. Overall, compared to existing toys, introduced toys had significantly lower levels of both E. coliand total coliforms. Results suggest that levels of fecal indicator bacteria contamination on children’s toys may be associated with access to improved water and sanitation conditions in the home. In addition, the fecal indicator bacteria levels on toys probably vary with duration in the household. Additional information on how these toys become contaminated is needed to determine the usefulness of toys as indicators or sentinels of water, sanitation and hygiene conditions, behaviors and risks