Qualitative Assessment of Effects of Encroachment on Water Resources of Agba Dam, Ilorin Nigeria

The city of Ilorin in Nigeria has experienced high population growth and rapid urbanization. Agba Dam is one of the major sources of potable water in Ilorin, and currently been threatened by anthropogenic induced encroachment activities, with potential for significant derogatory effects on its quality. Therefore, this paper assesses the qualitative impact of encroachment on the water resources regime of Agba Dam, Ilorin, Nigeria. Field survey was carried out to scope proximal anthropogenic activities and to delineate historical and current extent of the encroachment area of the dam. Representative water samples were collected from locations within the dam catchment, and subsequently analyzed for alkalinity, dissolved carbondioxide, chloride, total iron, copper, sulphate, colour, calcium, dissolved oxygen and turbidity. In addition, historical physical and chemical data of water samples obtained from the dam were also acquired, and analyzed to determine temporal variation in the quality. The results show a reduction of 0.89 km2 or 63% in the historical buffer boundary of the dam. The values of the measured physico-chemical parameters were generally similar to that obtained for the historical values and therefore suggest limited impact of the anthropogenic activities on the water quality. However, slight increases were observed in the measured concentrations of the alkalinity, dissolved carbondioxide, chloride, iron, copper and sulphate, and this indicates possibilities of water quality alteration, with potential consequences for ecosystem and aquatic life if the trend is unabated. Keywords: Anthropogenic, Water quality, Agba dam, Ilorin Nigeri

Cost of Corrosion of Metallic Products in Federal University of Agriculture, Abeokuta

The cost of corrosion has been increasing drastically due to the degradation of the metallic materials. This study was carried out to estimate the “Cost of Corrosion of Metallic Products in Federal University of Agriculture, Abeokuta (FUNAAB)”. Questionnaires were administered and interviews were also conducted to gather necessary information. The cost of corrosion from 2013-2015 was estimated and analysed with the aid of engineering economy method and statistical analysis method. For the cost of corrosion prevention methods, cleaning gave the highest cost contribution (69%), followed by the use of oil (30%), use of grease (1%), and painting gave zero percent of the total cost. While on the cost of corrosion maintenance methods, repair gave the highest cost contributions (66%), and prevention gave (34%) of the total cost. The overall cost of corrosion from (2013-2015) gave an upward trend, but a downward trend in future value and the annualized value. While the forecast cost from (2013-2016) at (95%) confidence level and (5%) significance level gave an upward trend. The present value, future value, and annualized value from (2013-2016) increased by (66%, 43%, and 75%) respectively. The total cost and the total annualized value of corrosion from (2013-2015) were estimated to be N 166,955,641 and N 93,791,024, and with the forecast (2013-2016) were found to be N 277,650,388 and N 163,672,460 respectively. Under the corrosion prevention methods and corrosion maintenance methods, cleaning and repair gave highest cost contribution respectively. Corrosion prevention methods need to be added to bring down the repair cost of those facilities for saving cost

Experimental Analysis of the Wear Properties of Carburized HSS (ASTM A600) Cutting Tool

Prediction and control of undesirable deterioration of cutting tools are the most essential challenges emanating in the design of tool which has to be checked. As a result of an increase in wear rate of HSS cutting tools, so has the need for wear resistant. The result has been a progression of carburizing the tools for better performance. Based on the theoretical analysis and study of tool wear and parameters that mitigates against wear resistance of cutting tools, this research work presents an experimental investigation and analysis of the wear properties of carburized HSS cutting tools. Twelve Samples under consideration were carburized HSS (ASTM A600) tools (0.65% C) treated at 800,850,900 and 950oC with holding time of 60, 90 and 120 minutes respectively. The wear properties of weight loss, wear volume, wear resistance and wear rate were carried out using Rotopol –V, impact tester, polisher, grinder and weight scale. It was found from the experiment carried out that cutting tool(sample 5) carburized at holding temperature and time of 800 oC and 90 minutes has the lowest cutting weight loss, volume and wear rate of 0.002 g, 0.00026 cm3 and 5.476 X10-10 cm2 with maximum wear resistance of 1.83X109 . This showed that sample 5 has the best wear properties which undermined the general believe that the sample with highest holding temperature and time should have the highest wear properties. This experiment has further established carburization as one of the heat treatment methods that involved carbon penetration to the depth that improved wear rate and resistance of a material

Isolation and characterisation of microorganisms contaminating herbal infusion sold in Minna, Nigeria

The microbiological assessment of ten herbal infusion samples from ten different locations in Minna, Niger State was investigated. The assessment of the microbial contamination on the herbal products was carried out, using standard methods. Pour plate method was used to cultivate serially diluted portions of the medicinal plant infusion samples. The results revealed that all the herbal preparations had the presence of microbial contaminants. The total heterotrophic counts of the different herbal samples ranged from 0 cfu/mL to 25.0 × 108cfu/mL while the total fungal counts ranged from 3.0×106cfu/mL to 3.5×108cfu/mL. The total viable bacteria counts showed that the highest counts of 25.0 × 108cfu/mL was recorded in the sample from Bosso and the least counts of 0 cfu/mL from Kasuwan-Gwari while the total fungal counts showed that the highest count of 3.5×108cfu/mL was found in the sample obtained from FUT campus and the least counts of 3.0×106cfu/mL in the sample from Mai-Kunkele. One way analysis of variance (ANOVA) showed that there was significant difference (p<0.05) in the microbial load of the herbal infusions from each location. The microbial isolates identified were E. coli, Staphylococcus aureus, Shigella sp, Klebsiella sp, Pseudomonas sp, Micrococcus sp, Salmonella sp, Aspergillus sp, Penicillium sp and Saccharomyces cerevisaie. Members of the genus Aspergillus were found to be predominant. This suggests that the herbal infusion harbors microorganisms that could be hazardous to human health and hence producers should maintain the highest possible level of hygiene during the processing and packaging of the products in order to ensure safety of the products

Investigation of Wear Land and Rate of Locally Made HSS Cutting Tool

Production technology and machining are inseparable with cutting operation playing important roles. Investigation of wear land and rate of cutting tool developed locally (C=0.56%) with an HSS cutting tool (C=0.65%) as a control was carried out. Wear rate test was carried out using Rotopol –V and Impact tester. The samples (12) of locally made cutting tools and one (1) sample of a control HSS cutting tool were weighed to get the initial weight and grit was fixed at a point for the sample to revolve at a specific time of 10 mins interval. Approach of macro transfer particles that involved mechanism of abrasion and adhesion which was termed as mechanical wear to handle abrasion adhesion processes was used in developing equation for growth wear at flank. It was observed from the wear test that best minimum wear rate of 1.09 x10-8 and 2.053x10-8 for the tools developed and control were measured. MATLAB was used to simulate the wear land and rate under different conditions. Validated results of both the experimental and modeling showed that cutting speed has effect on wear rate while cutting time has predicted measure on wear land. Both experimental and modeling result showed best performances of tools developed over the control

Polymer-drug nanoconjugate – an innovative nanomedicine: challenges and recent advancements in rational formulation design for effective delivery of poorly soluble drugs.

The published manuscript is available at EurekaSelect via - See more at: http://dx.doi.org/10.2174/2211738504666160213001714Abstract Background: Over the last four decades, the use of water soluble polymers in rational formulation design has rapidly evolved into valuable drug delivery strategies to enhance the safety and therapeutic effectiveness of poorly soluble drugs, particularly anticancer drugs. Novel advances in polymer chemistry have provided new generations of well defined polymeric architectures for specific applications in polymer-drug conjugate design. However, total control of crucial parameters such as particle size, molecular weight distribution, polydispersity, localization of charges, hydrophilic-lipophilic balance and non site-specific coupling reactions during conjugation has been a serious challenge. Objective: This review briefly describes the current advances in polymer-drug nanoconjugate design and various challenges hindering their transformation into clinically useful medicines. Method: Existing literature was reviewed. Results: This review provides insights into the significant impact of covalent and non-covalent interactions between drug and polymer on drug loading [or conjugation] efficiency, conjugate stability, mechanism of drug release from the conjugate and biopharmaceutical properties of poorly soluble drugs. The utility values and application of Quality by Design principles in rational design, optimization and control of the Critical Quality Attributes [CQA] and Critical Process Parameters [CPP] that underpin the safety, quality and efficacy of the nanoconjugates are also presented. Conclusion: It was apparent that better understanding of the physicochemical properties of the nanoconjugates as well as the drug-polymer interaction during conjugation process is essential to be able to control the biodistribution, pharmacokinetics, therapeutic activity and toxicity of the nanoconjugates which will in turn enhance the prospect of successful transformation of these promising nanoconjugates into clinically useful nanomedicines

The Challenges and Panaceas to Power Distribution Losses in Nigeria

Energy losses in the distribution network and its subsystems&nbsp;have been issues&nbsp;of great concerns&nbsp;in Nigeria’s power sector. For decades, several studies have been conducted on the challenges facing the power sector in Nigeria with most focus directed on the distribution subsystems. The major challenge in the distribution system is the high energy losses which are detrimental to the techno-economic benefits of the power systems. However, details of the distribution system challenges&nbsp;and the probable solutions have not been efficiently presented. In this study, some of these challenges are presented and the potential solutions are proposed. The features of the Nigeria distribution network, the technical and non-technical sources of losses as well as the identified challenges are presented before discussing&nbsp;the potential solutions. The panaceas so provided were from the understanding of some published works and other related materials as well as the in-depth understanding of the authors. This article can serve as a guide for the utilities and stakeholders in the power sector for efficient management operations and improved customer service delivery

Physical and immunological aspects of exercise in chronic diseases.

Physical inactivity and sedentary lifestyles are believed to be independent risk factors for the occurrence of numerous diseases, including, obesity, Type 2 diabetes, metabolic syndrome, cardiovascular disease, cancer and mental health, all leading to substantial morbidity and/or premature death. It has been found that regular exercise, is associated with better quality of life and health outcomes, and reduces the risk of cardiovascular disease and cancer. Here, we review the effects regular exercise has on mental health and well-being, on the immune system and in cancer, cardiovascular disease, autoimmunity and metabolic syndrome. Is exercise the new immunotherapy to treat diseases

The Study of the Impact of Nano Carbon Additives on Astm A53 Mild Steel During Machining

In the world today, most of the treated steels were done using chemicals which in turn degrades rapidly. This study developed treated metal from ASTM A53 mild steel using pulverized palm kernel shell as carburizer and egg shell as energizer due to their high carbon and calcium carbonate content. Samples of hundred (100) pieces of ASTM A53 mild steel with dimensional size of 100 x 30 mm each were used. The elemental composition of the sample was checked using UV-VIZ spectrometric machine. Four sets of steel boxes were fabricated in the dimensions of 200 x 50 x 200 mm with two faces detachable and small extension for carrying the boxes at high temperature. Prepared samples buried in pulverized carburizer and energizer at a mixed percentage ratio of 80 to 20 were put together in a muffle furnace (2,500oC max) for case hardening at different holding temperature and time of (HT- 60, 90, 120 and 180 minutes) and (CT- 950, 1000, 1050, 1100OC). This procedure was repeated severally with varying holding time and temperatures. The initial experiment started from 950oC and rose up to1100oC. The hardness for surface, interface and core were taken using hardness tester. Surface hardness of 139.4 HV at holding temperature 980oC and time 180 minutes gave best increase of 43% over the control of 79.7 HV while hardness at interface and core were 146 HV and 147 HV with percentages increase of 9 and 15.3 was achieved. The findings in this study also confirmed that waste materials with some element of carbon can be used to replace foreign chemicals intended for the same purpose

Cardiac metastases

We report a case of esophageal cancer with symptomatic metastases to the heart; the patient was treated with short-course radiotherapy with good symptomatic relief. We reviewed the current literature regarding the epidemiology, clinical presentation, diagnostic tools, treatment modalities, and the prognosis of cardiac metastases. In this report we summarize the most recent autopsy studies (published between 1975 and 2007), in which we found an autopsy incidence of cardiac metastases of 2.3% among the general population, while the incidence among autopsies of cancer patients was 7.1%. Therefore, we share the opinion with others that there has been an increase in the incidence of cardiac metastases among cancer patients diagnosed after 1970, in comparison with the reported incidences in older series before 1970 (7.1% vs 3.8%; Kruskal-Wallis rank test; P = 0.039). Special attention was given to the role of radiotherapy in the management of cardiac metastases