IN CONSPECTU PROPE TOTIUS URBIS: LA APLICACIÓN DE DIFERENTES MÉTODOS DE ANÁLISIS DE VISIBILIDAD AL PAISAJE DEL AGER TARRACONENSIS

We present in this paper the results of the application of several visual methods on a group of locations, dated between VI and I centuries BC, of the ager tarraconensis (Tarragona,Spain) a hinterland of the roman colony of Tarraco. The difficulty in interpreting the diverse results in a combined way has been resolved by means of the use of statistical methods as Principal Components Analysis (PCA) and K-means clustering analysis. These methods have allowed us to carry out site classifications in function of the landscape visual structure that contains them and of the visual relationships that could be given among them. Also we have created and analized some visual networks in order to study the visual cohesion among the settlements.Presentamos en este artículo el resultado de la utilización de diversos métodos de análisis aplicados sobre un grupo de yacimientos datados entre los siglos VI y I a.C. Todos ellos pertenecen al llamado ager tarraconensis (Tarragona, España) es decir el hinterland de la colonia romana de Tarraco. La dificultad en interpretar los variados resultados obtenidos por diferentes aproximaciones ha sido resuelta mediante la aplicación de métodos estadísticos, como Análisis de Componentes Principales (ACP) y Análisis Clutens K-means. Estos métodos nos han permitido realizar clasificaciones de yacimientos en función de la estructura visual del paisaje que los contiene y de las interrelaciones que puedan producirse entre ellos. También se han creado redes visuales para analizar las posibles formas de cohesión visual en el territorio

Integración de tecnologías SGDB, SIG y GPS en la planificación, desarrollo y análisis de las prospecciones intensivas del Ager Tarraconensis

Se expone en este artículo la metodología de prospección desarrollada en el marco del estudio arqueológico del paisaje del Ager Tarraconensis (al occidente del río Francolí). Experiencias de prospección previas ayudaron en el desarrollo de metodologías que integrasen sistemas gestores de bases de datos (SGBD) y sistemas de información geográfica (SIG). La campaña de prospecciones intensivas que presentamos consideró desde la fase de planificación estas nuevas tecnologías, a las que se sumaron los sistemas de posicionamiento global (GPS) y el desarrollo de una base cartográfica georefenciada. Mediante la integración de tecnologías SGBD, SIG y GPS se pretende superar las dificultades que plantea la gestión de la gran cantidad de información generada por los seis diferentes equipos de campo que participan en el proyecto. Asimismo, gracias a la metodología utilizada la generación de planos de prospección se automatiza, reduciendo significativamente el tiempo empleado en el trabajo de laboratorio y ayudando a la distribución de las áreas de trabajo de los diversos equipos. En la fase de procesado de datos el tratamiento en SIG resultará esencial, no solamente por su capacidad de integración de datos procedentes de otros estudios con base cartográfica, sino por el tratamiento estadístico al que puede someter estos datos que resultarà en la producción de planos temáticos que reflejen eficazmente la complejidad de los resultados.In this article it is intended to show the surveying methodology developed in the framework of the Ager Tarraconensis project. Previous surveying experiences in the study area contributed to the development of methodologies allowing the integration of database management systems (DBMS) and geographic information systems (GIS). The addition of Global Positioning System (GPS) and the development of a georeferenced cartographic reference archive were employed from the early planning stages. By means of the use of new technologies, it is our purpose to overcome difficulties deriving from the large amount of data generated by the six independent field teams which integrate the project. Likewise, surveying maps generation is automatised, reducing considerably the amount of time invested and also helping the distribution of work areas among the teams. At the stage of data processing, GIS will turn out essential due to its capacity of integrating data from other studies and producing thematic maps which will effectively reflect the complexity of the survey outcomes

In conspectu prope totius urbis: an application of different visual methods at the ager Tarraconensis landscape

We present in this paper the results of the application of several visual methods on a group of locations, dated between VI and I centuries BC, of the ager Tarraconensis (Tarragona, Spain) a Hinterland of the roman colony of Tarraco. The difficulty in interpreting the diverse results in a combined way has been resolved by means of the use of statistical methods, such as Principal Components Analysis (PCA) and K-means clustering analysis. These methods have allowed us to carry out site classifications in function of the landscape's visual structure that contains them and of the visual relationships that could be given among them

Incidence of dyslipidemia in people with HIV who are treated with integrase inhibitors versus other antiretroviral agents

Objective: To compare the incidence of dyslipidemia in people with HIV receiving integrase inhibitors (INSTI) versus boosted protease inhibitors (PI/b) and nonnucleoside reverse transcriptase inhibitors (NNRTI) within RESPOND consortium of prospective cohorts. Methods: Participants were eligible if they were at least 18 years, without dyslipidemia and initiated or switched to a three-drug antiretroviral therapy (ART)-regimen consisting of either INSTI, NNRTI, or PI/b for the first time, between 1 January 2012 and 31 December 2018. Dyslipidemia was defined as random total cholesterol more than 240 mg/dl, HDL less than 35 mg/dl, triglyceride more than 200 mg/dl, or initiation of lipid-lowering therapy. Poisson regression was used to determine the adjusted incidence rate ratios. Follow-up was censored after 3 years or upon ART-regimen discontinuation or last lipid measurement or 31 December 2019, whichever occurred first. Results: Overall, 4577 people with HIV were eligible (INSTI = 66.9%, PI/b = 12.5%, and NNRTI = 20.6%), 1938 (42.3%) of whom were ART-naive. During 1.7 (interquartile range, 0.6-3.0) median years of follow-up, 1460 participants developed dyslipidemia [incidence rate: 191.6 per 1000 person-years, 95% confidence interval (CI) 182.0-201.7]. Participants taking INSTI had a lower incidence of dyslipidemia compared with those on PI/b (adjusted incidence rate ratio 0.71; CI 0.59-0.85), but higher rate compared with those on NNRTI (1.35; CI 1.15-1.58). Compared with dolutegravir, the incidence of dyslipidemia was higher with elvitegravir/cobicistat (1.20; CI 1.00-1.43) and raltegravir (1.24; CI 1.02-1.51), but lower with rilpivirine (0.77; CI 0.63-0.94). Conclusion: In this large consortium of heterogeneous cohorts, dyslipidemia was less common with INSTI than with PI/b. Compared with dolutegravir, dyslipidemia was more common with elvitegravir/cobicistat and raltegravir, but less common with rilpivirine