Influence of processing methods on the quality attributes of bio-fortified sweet potato products

Bio-fortified sweet potato (BSP) is one of the crops that can be used to address the problems of vitamin A deficiency in the Sub-Saharan Africa but it’s currently being underutilized. This study seeks to evaluate the effects of different heat processing methods on the quality of products made from BSP in order to increase its utilization. Freshly harvested tubers were purchased from a Research Farm in Federal University of Agriculture, Abeokuta (FUNAAB), Nigeria and brought to the Processing Centre, Nigerian Stored Products Research Institute (NSPRI), Ilorin. The sample was taken through some standard pre-processing operations of sorting, peeling, washing, slicing (2.11 mm), and deep frying (3 minutes) while some portions were boiled immediately after sorting with or without skin for 10–15 minutes. Each treated sample was analysed for sensory, proximate, vitamins and mineral compositions following standard methods. Results showed that fried sample had highest acceptability for aroma (7.25) and crispiness (7.00) while sample boiled without skin (15 min) was rated with least scores in colour (5.30), appearance (5.40), texture (4.95), crispiness (4.65) and overall acceptability (5.70). Protein, vitamin C, phenolics, flavonoids and reducing sugar contents were 6.53–18.52%, 10.89–76.69 mg/100 g, 0.57–3.15 mg/L, 94.64–383.91 mg/L and 43.05–237.12 g/100 g respectively while some minerals such as Na, K and Zn ranged from 8.42–17.45, 5.12–9.30 and 0.03–0.09 mg/L respectively. Different heat processing at different durations affected the sensory attributes, nutritional and mineral compositions of BSP. Key words: Post-harvest, food security, potato, heat treatment, qualit

Probing exotic phenomena at the interface of nuclear and particle physics with the electric dipole moments of diamagnetic atoms: A unique window to hadronic and semi-leptonic CP violation

The current status of electric dipole moments of diamagnetic atoms which involves the synergy between atomic experiments and three different theoretical areas -- particle, nuclear and atomic is reviewed. Various models of particle physics that predict CP violation, which is necessary for the existence of such electric dipole moments, are presented. These include the standard model of particle physics and various extensions of it. Effective hadron level combined charge conjugation (C) and parity (P) symmetry violating interactions are derived taking into consideration different ways in which a nucleon interacts with other nucleons as well as with electrons. Nuclear structure calculations of the CP-odd nuclear Schiff moment are discussed using the shell model and other theoretical approaches. Results of the calculations of atomic electric dipole moments due to the interaction of the nuclear Schiff moment with the electrons and the P and time-reversal (T) symmetry violating tensor-pseudotensor electron-nucleus are elucidated using different relativistic many-body theories. The principles of the measurement of the electric dipole moments of diamagnetic atoms are outlined. Upper limits for the nuclear Schiff moment and tensor-pseudotensor coupling constant are obtained combining the results of atomic experiments and relativistic many-body theories. The coefficients for the different sources of CP violation have been estimated at the elementary particle level for all the diamagnetic atoms of current experimental interest and their implications for physics beyond the standard model is discussed. Possible improvements of the current results of the measurements as well as quantum chromodynamics, nuclear and atomic calculations are suggested.Comment: 46 pages, 19 tables and 16 figures. A review article accepted for EPJ

CP-Violating Effects in Neutralino Scattering and Annihilation

CP-violating effects that mix the CP-even and CP-odd Higgs bosons can have important consequences for annihilation and scattering of supersymmetric neutralino dark matter. Specifically, we study the dependence on the phase of the third generation trilinear couplings At and Ab. We find enhancements in the neutralino annihilation scattering rate which are typically factors of one to four; in the narrow regime of parameter space with neutralino mass close to half the Higgs mass, we find new (CP violating) resonances which may increase the annihilation cross section by factors up to 106. CP-violating effects can also modify the neutralino scattering rate off nucleons. For cross sections accessible to upcoming experiments, the rate can be enhanced by a factor as large as 2 or suppressed by a factor of up to 3; for lower cross sections, the suppression can be as large as seven orders of magnitude. We find cases in the region being probed by dark matter searches which are experimentally or cosmologically excluded when CP is conserved but are allowed when CP is violated. These effects are important for direct and indirect detection of neutralino dark matter in cryogenic detectors, the Earth, the Sun, the galactic halo and the galactic center.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/49125/2/jhep072002052.pd

Whole-genome sequencing reveals host factors underlying critical COVID-19

Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care1 or hospitalization2,3,4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes—including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)—in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease

Chemical and physico-chemical properties of orange fleshed sweet potatoes (OFSP) chips dried using solar dyers

In this study, drying technology was employed to process fresh orange fleshed sweet potatoes (OFSP) into dried slices using NSPRI improved solar tent dryer, parabolic shaped solar tent dryer in comparison with open air drying and its effect on the chemical, physico-chemical and mineral constituents of dried OFSP slices was investigated. Results showed that the dried-OFSP contained ash (3.69-4.09 %), fat (4.09-5.09 %), crude fibre (4.69-5.15 %), protein (5.87-8.28 %), carbohydrate (78.22-82.21 %), vitamin C (8.55-20.49 mg/100g), phenolics (0.1-1.28 mg/kg), flavonoids (984-145 mg/kg) and reducing sugar (35.01-82.23 g/100g). The total titratable acidity of the dried OFSP slices varied between 0.56-0.89 %, total soluble solids ranged between 5.70-7.00 °Brix while pH ranged between 4.94-6.47. Zinc, magnesium, potassium, calcium, sodium, iron were present in varying levels but aluminium, lead and cadmium were not detected in all the samples. This study therefore showed that good quality dried OFSP slices with appreciable nutrient content can be obtained from drying in NSPRI solar tent dryers especially with the use of the parabolic shaped solar tent dryer. Thus, the parabolic solar tent dryer is recommended for drying crops. Keywords: Drying technology, Orange fleshed sweet potato, NSPRI solar dyers, Physicochemical propertie

Freqüência de anticorpos homólogos anti-Borrelia burgdorferi em eqüinos na mesorregião metropolitana de Belém, Estado do Pará Occurrence of homologous anti-Borrelia burgdorferi antibodies in equines in the metropolitan mesorregion of Belém, State of Para, Brazil

Espiroquetas transmitidas por carrapatos são microrganismos de ampla distribuição geográfica e acometem animais silvestres, domésticos e seres humanos. Procedeu-se a análise sorológica de 300 soros de eqüinos onde 58 animais eram do município Ananideua, 61 eram de Belém, 131 de Castanhal e 50 eram do município de Santa Izabel do Pará para Borrelia burgdorferi através do teste ELISA indireto. Não foram observadas diferenças significativas (P < 0,05) entre os municípios, nem quanto à raça, sexo e função dos animais. Um total de 80 (26,7%) animais foram positivos para B. burgdorferi com os títulos de 1:800, 72 (90%) eqüinos; 1:1.600, 6 (7,5%) eqüinos; e 1:3.200, 2 (2,5%) eqüinos. Os resultados observados foram similares aos descritos nos EUA, onde foram relatadas freqüências de soropositivos variando entre 7 e 75% em eqüinos assintomáticos. A presença de anticorpos homólogos contra B. burgdorferi em eqüinos na mesorregião metropolitana de Belém é indicativo da ampla distribuição do agente e da possibilidade de ocorrerem casos humanos deste agente na região.<br>Spirochaetes transmitted by ticks are microorganisms of worldwide distribution, which infect wild, domestic animals and human beings. A total of 300 equine sera from four municipalities: Ananideua (58), Belém (61), Castanhal (131), and Santa Izabel do Pará (50), were evaluated for Borrelia burgdorferi by an Elisa test. There were no significant differences (P<0.05) among municipalities, breed, sex or husbandry. A total of 80 (26.7%) horses were B. burgdorferi positive with titles of 1:800, 72 (90%) horses, 1:1.600, 6 (7.5%) horses, and 1:3.200, 2 (2.5%) horses. The results were similar to those in the USA, where related frequencies ranged from 7 to 75% in asymptomatic seropositive horses. The presence of anti-B.burgdorferi homologous antibodies in horses from four municipalities in the metropolitan mesorregion of Belém suggests the possibility of occurrence of human cases in the region