Select effective fasciolicides to control sheep liver fluke

International Fund for Agricultural Developmen

Climate Change, Gender Inequality and Migration in East Africa

East Africa, one of the most volatile regions in Africa, has been suffering from enormous problems caused by population growth, weak governance, war, and famine. Recently, the advent of climate change has exacerbated these pre-existing problems. These impacts are not felt equally across populations, and, according to various studies, disproportionately affect women. Despite reforms, rural East African women still struggle to access resources or participate in decision-making processes. As a result, they have a weaker ability to adapt to climate change than men. This weaker adaptive capacity influences migration patterns between the genders, and creates its own set of problems. Indeed, migration influenced by climate change forces women to take greater roles at home and confront increased violence. While not fully understood, there is growing evidence of the connection between climate change, migration, and gender disparities. Addressing these issues in isolation cannot bring a sustainable solution, but this article will explore the legal and policy measures needed to solve the complex societal and ecological problems facing the region. Through international collaboration, East Africa can take action to improve the lives of women, limit violence, and fight back against the rapidly changing climate

Seroepidemiology of hepatitis B virus in Addis Ababa Ethiopia: transmission patterns and vaccine control

A community-based seroepidemiological survey of Addis Ababa, Ethiopia was conducted in 1994 to inform on the transmission dynamics and control of hepatitis B virus (HBV) infection. Venous blood from 4736 individuals under 50 years of age from 1262 households, selected using stratified cluster-sampling, was screened for HBV markers using commercial ELISAs. HBsAg prevalence was 7% (95% CI 6–8), higher in males (9%; 7–10) than females (5%; 4–6). HBeAg prevalence in HBsAg positives was 23% (18–29), and less than 1% of women of childbearing age were HBeAg positive. Overall HBV seroprevalence (any marker), rose steadily with age to over 70% in 40–49 year olds, indicating significant childhood and adult transmission. Estimated instantaneous incidence was 3–4/100 susceptibles/year, higher in males than females in 0–4 year olds, and peaking in early childhood and young adults. The age at which 50% had evidence of infection was around 20 years, and the herd immunity threshold is approximated at 63–77%. Addis Ababa is of intermediate-high HBV endemicity, with negligible perinatal transmission. Our main findings are the identification of a significant difference between males and females in the age-acquisition of HBV infection, and marked differences between age groups in HBV incidence rates. These results should target future research studies of underlying risk factors. Furthermore, we generate a crude estimate of the level of coverage of HBV vaccine that would be required to eliminate the virus from the study population

The Impact of Soil and Water Conservation Program on the Income and Productivity of Farm Households in Adama District, Ethiopia

Land degradation due to soil erosion and nutrient depletion is one of the main problems constraining the development of the agricultural sector in Ethiopia. As part of intervention activities a number of soil and water conservation (SWC) practices have been promoted to smallholder farmers living in highly degraded and drought prone areas of the country. This study was conducted to assess the impact of SWC intervention on the livelihood of smallholder farm households in terms household income and productivity. To meet this objective primary data was gathered in 2012 from 101 SWC program participants and 115 non-participants that were randomly selected from 3 intervention area and 3 counterfactual villages respectively. Descriptive and inferential statistics and propensity score matching (PSM) models were used to address the stated objectives. Results of the descriptive statistics showed that before matching there was statistically significant difference between program participants and their counterfactual households in terms of sex and age of household head, family size and farm size generally in favor of program participants. Results of the PSM model revealed that SWC intervention did not result in significant difference between program participant and nonparticipant households in terms of total crop and household income, and crop yield. However it was to be noted that there were positive trends which all together should guide SWC policy makers to identify important factors influencing the contribution of such a program and reconsider the design and implementation of the interventionsKeywords: Soil and water, Conservation practices, Impact, Oromia regio

Perception of High School Students towards Voluntary HIV Counseling and Testing, using Health Belief Model in Butajira, SNNPR

Background: Voluntary counseling and testing (VCT) for HIV is one of the strategies for HIV/AIDS prevention, and yet, there is very little information on what influences the services in Ethiopia. Objective: To assess the perception and attitude of students towards VCT services using the Health Belief Model. Methods: A cross sectional descriptive study was conducted in January 2006, among Butajira senior secondary school students where a multi stage sampling method was used. Results: About ninety seven percent of the students had heard about VCT services but less than one fifth of them had undergone VCT. Eighty two percent of the students were willing to undergo VCT. It was shown that willingness to VCT was significantly associated with perceived susceptibility [AOR=0.37(0.28, 0.89)], perceived barrier [AOR= 0.45 (0.23, 0.89)] and perceived benefit [AOR=1.79 (1.44, 2.49)]. Conclusions: The majority of students had heard about VCT and revealed willingness to undergo VCT. High perceived susceptibility and barriers were associated with low willingness to undergo VCT. On the other hand, students with high perceived benefits showed better willingness to undergo VCT. It is recommended that messages onVCT give emphasis on personal susceptibility to HIV/AIDS and benefits of VCT

Sero-epidemiology of rubella in the urban population of Addis Ababa Ethiopia

We conducted a community-based cluster sample survey of rubella sero-epidemiology in Addis Ababa, Ethiopia in 1994. Among 4666 individuals for whom complete data were available, rubella antibody prevalence was 91% (95% confidence interval: 90, 92). On multivariable analysis, seroprevalence was lower among individuals who were resident in Addis Ababa for 1 year or less. Approx. 50% seroprevalence was attained by age 4 years, and the estimated average age at infection was 5·2 years. The highest age-specific force of infection was estimated to occur in 5- to 9-year-olds. The early age at infection corresponded with a low estimated incidence of congenital rubella syndrome (CRS) of 0·3 per 1000 live births, equivalent to nine cases of CRS in 1994. The predicted critical level of immunity for elimination of rubella via vaccination was 85–91%, requiring 89–96% coverage with a vaccine of 95% effectiveness. Unless very high coverage of rubella vaccine could be guaranteed, the introduction of childhood vaccination could increase the incidence of CRS in Addis Ababa

Combined inhibition of IGF-1R pathway and HDAC blocks Uveal Melanoma cell survival and induces apoptosis.

https://openworks.mdanderson.org/sumexp22/1146/thumbnail.jp

Draft Genome Sequence of Photorhabdus temperata Strain Meg1, an Entomopathogenic Bacterium Isolated from Heterorhabditis megidis Nematodes

Photorhabdus temperata strain Meg1 is an entomopathogenic bacterium that forms a symbiotic association with Heterorhabditis nematodes. We report here a 4.9-Mbp draft genome sequence for P. temperata strain Meg1, with a G+C content of 43.18% and containing 4,340 candidate protein-coding genes

Fertility Desire and Contraceptive Utilization among People Living With HIV/AIDS on ART in Hosanna Town, Southern Ethiopia

HIV positive individuals may or may not have intention to have children. They could also have different degrees of utilization and demand for contraception. The desire of HIV infected persons to have children in the future has implication for the transmission of HIV to sexual partners or newborns. The study was designed to assess the fertility desire and contraceptive utilization among PLWHAs on ART in Hossana town. institutional based cross sectional study supplemented by in-depth  interview was conducted from January to March 2010 on total sample of 321 who were on ART. Women 18-49 years and men 18-59 years were included. Data was entered by using EPI info 2000 then exported and  analyzed by SPSS 17.0. Total of 117 (36.45%) of respondents were   desiring children. Respondents with no children (AOR 60.89, 95% CI  8.02-462.05), those who intended to use family planning in the future (AOR 4.35, 95% CI 1.61-11.73) were more likely to desire children. 102(31.8%) were using family planning. Being married (AOR 7.83, 95% CI 1.08-56.79), having three or more children (AOR 4.54, 95% CI  1.12-18.48), and having knowledge on mother to child transmission (AOR 4.29, 95% CI 1.98-9.26) plan to have children in the future (AOR 0.29, 95% CI 0.1-0.82) were significantly associated with family planning. A highproportion of HIV positive individuals desired children. A better and   evidence based understanding of fertility intentions and demand for contraception was needed to promote and protect women and men living  with HIV/AIDs to make informed decisions about reproduction and to have access to appropriate sexual reproductive health services