180 research outputs found

    Personality Type A or Personality Type D, Which is a Strong Predictor of Coronary Heart Disease?

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    Considering the increasing incidence and prevalence of coronary heart disease and the increasing emphasis of health researchers on the association and relationship of psychosocial factors with the occurrence and persistence of cardiovascular disease, the need to identify the desired factors and determine each of the personality and psychological factors. The effect is felt more than ever in patients who are also the target of the present study. The main purpose of this study was to determine the predictors of coronary heart disease based on personality types. Among cardiovascular patients, men and women aged 25-60 years in Shahid Madani and 29 Bahman hospitals in Tabriz, who were admitted to surgical wards for coronary angiography in 2015, 50 people were selected who met the inclusion criteria. Also, 50 patients were selected from the patients' companions and answered the questionnaires of Denollet type D personality and Ratus personality pattern questionnaire. Findings showed that the variables of negative emotions, social inhibition of the personality type D subscale were predictors of coronary heart disease. But the role of personality type A in predicting coronary heart disease is not significant. Social inhibition was also the strongest predictor of coronary heart disease. The present study showed that personality factors are predictors of coronary heart disease

    Assessment of different anther culture approaches to produce doubled haploids in cucumber (Cucumis sativus L.)

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    [EN] Cucumber is one of the most important vegetable crops worldwide, which makes it a good candidate to produce doubled haploid (DH) lines to accelerate plant breeding. Traditionally, these approaches involved induction of gynogenesis or parthenogenesis with irradiated pollen, which carries some disadvantages compared to androgenesis. Despite this, studies on anther/microspore cultures in cucumber are surprisingly scarce. Furthermore, most of them failed to unambiguously demonstrate the haploid origin of the individuals obtained. In this work we focused on anther cultures using two cucumber genotypes, different previously published protocols for anther culture, different in vitro culture variants to make it more efficient, and most importantly, a combination of flow cytometry and microsatellite molecular markers to evaluate the real androgenic potential and the impact of anther wall tissue proliferation. We developed a method to produce DH plants involving a bud pretreatment at 4 C, a 35 C treatment to anthers, culture with BAP and 2,4-D, and induction of callus morphogenesis by an additional 35 C treatment and sequential culture first in liquid medium in darkness and second in solid medium with light. We also found that factors such as genotype, proliferation of anther wall tissues, orientation of anthers in the culture medium and growth regulator composition of the initial anther culture medium have a remarkable impact. Our rate of chromosome doubling (81%) was high enough to exclude additional chromosome doubling steps. Together, our results present androgenesis as an improvable but yet more convenient alternative to traditional gynogenesis and parthenogenesis-based approaches.Thanks are due to all the whole staff of the Cell Biology Group for helping and training AA during his stay in the group. This work was supported by Grant AGL2017- 88135-R to JMSS from Spanish Ministerio de EconomıŽa y Competitividad (MINECO) jointly funded by FEDER.Asadi, A.; Zebarjadi, A.; Abdollahi, MR.; SeguĂ­-Simarro, JM. (2018). Assessment of different anther culture approaches to produce doubled haploids in cucumber (Cucumis sativus L.). Euphytica. 214(216):1-17. https://doi.org/10.1007/s10681-018-2297-xS117214216Abdollahi MR, Najafi S, Sarikhani H, Moosavi SS (2016) Induction and development of anther-derived gametic embryos in cucumber (Cucumis sativus L.) by optimizing the macronutrient and agar concentrations in culture medium. Turk J Biol 40(3):571–579Ashok Kumar HG, Murthy HN (2004) Effect of sugars and amino acids on androgenesis of Cucumis sativus. Plant Cell, Tissue Organ Cult 78(3):201–208. https://doi.org/10.1023/b:ticu.0000025637.56693.68Bai B, Su YH, Yuan J, Zhang XS (2013) Induction of somatic embryos in arabidopsis requires local YUCCA expression mediated by the down-regulation of ethylene biosynthesis. Mol Plant 6(4):1247–1260. https://doi.org/10.1093/mp/sss154Claveria E, Garcia-Mas J, Dolcet-Sanjuan R (2005) Optimization of cucumber doubled haploid line production using in vitro rescue of in vivo induced parthenogenic embryos. J Am Soc Hortic Sci 130(4):555–560Corral-MartĂ­nez P, Nuez F, SeguĂ­-Simarro JM (2011) Genetic, quantitative and microscopic evidence for fusion of haploid nuclei and growth of somatic calli in cultured ms1035 tomato anthers. Euphytica 178(2):215–228. https://doi.org/10.1007/s10681-010-0303-zDanin-Poleg Y, Reis N, Tzuri G, Katzir N (2001) Development and characterization of microsatellite markers in Cucumis. Theor Appl Genet 102(1):61–72. https://doi.org/10.1007/s001220051618Dong Y-Q, Zhao W-X, Li X-H, Liu X-C, Gao N-N, Huang J-H, Wang W-Y, Xu X-L, Tang Z-H (2016) Androgenesis, gynogenesis, and parthenogenesis haploids in cucurbit species. Plant Cell Rep. https://doi.org/10.1007/s00299-016-2018-7FAOSTAT (2018) http://faostat.fao.org. Accessed July 2018Ficcadenti N, Sestili S, Annibali S, Di Marco M, Schiavi M (1999) In vitro gynogenesis to induce haploid plants in melon Cucumis melo L. Genet Breed 53:255–257GaƂązka J, Niemirowicz-Szczytt K (2013) Review of research on haploid production in cucumber and other cucurbits. Folia Hortic. https://doi.org/10.2478/fhort-2013-0008Hamidvand Y, Abdollahi MR, Chaichi M, Moosavi SS (2013) The effect of plant growth regulators on callogenesis and gametic embryogenesis from anther culture of cucumber (Cucumis sativus L.). Int J Agric Crop Sci 5(10):1089Kurtar ES, Balkaya A, Kandemir D (2016) Evaluation of haploidization efficiency in winter squash (Cucurbita maxima Duch.) and pumpkin (Cucurbita moschata Duch.) through anther culture. Plant Cell, Tissue Organ Cult 127(2):497–511. https://doi.org/10.1007/s11240-016-1074-6Lotfi M, Alan AR, Henning MJ, Jahn MM, Earle ED (2003) Production of haploid and doubled haploid plants of melon (Cucumis melo L.) for use in breeding for multiple virus resistance. Plant Cell Rep 21(11):1121–1128Metwally EI, Moustafa SA, El-Sawy BI, Shalaby TA (1998) Haploid plantlets derived by anther culture of Cucurbita pepo. Plant Cell, Tissue Organ Cult 52(3):171–176. https://doi.org/10.1023/a:1005908326663Mohamed M, Refaei E (2004) Enhanced haploids regeneration in anther culture of summer squash (Curcurbita pepo L.). Cucurbit Genet Coop Rep 27:57–60Murashige T, Skoog F (1962) A revised medium for rapid growth and bioassays with tobacco tissue cultures. Physiol Plant 15:473–479Parra-Vega V, Renau-Morata B, Sifres A, SeguĂ­-Simarro JM (2013) Stress treatments and in vitro culture conditions influence microspore embryogenesis and growth of callus from anther walls of sweet pepper (Capsicum annuum L.). Plant Cell, Tissue Organ Cult 112(3):353–360. https://doi.org/10.1007/s11240-012-0242-6Rakha M, Metwally E, Moustafa S, Etman A, Dewir Y (2012) Evaluation of regenerated strains from six Cucurbita interspecific hybrids obtained through anther and ovule in vitro cultures. Aust J Crop Sci 6(1):23–30Saghai-Maroof MA, Soliman KM, Jorgensen RA, Allard RW (1984) Ribosomal DNA spacer-length polymorphisms in barley: mendelian inheritance, chromosomal location, and population dynamics. Proc Natl Acad Sci USA 81(24):8014–8018. https://doi.org/10.1073/pnas.81.24.8014Sauton A, Dumas de Vaulx R (1987) Obtention de plantes haploides chez melon (Cucumis melo L.) par gynogenese indute par du pollen irraidiĂ©. Agronomie 7:141–148SeguĂ­-Simarro JM (2016) Androgenesis in solanaceae. In: GermanĂ  MA, Lambardi M (eds) In vitro embryogenesis. Methods in molecular biology, vol 1359. Springer, New York, pp 209–244. https://doi.org/10.1007/978-1-4939-3061-6_9SeguĂ­-Simarro JM, Nuez F (2006) Androgenesis induction from tomato anther cultures: callus characterization. Acta Hort 725:855–861SeguĂ­-Simarro JM, Nuez F (2007) Embryogenesis induction, callogenesis, and plant regeneration by in vitro culture of tomato isolated microspores and whole anthers. J Exp Bot 58(5):1119–1132SeguĂ­-Simarro JM, Nuez F (2008) Pathways to doubled haploidy: chromosome doubling during androgenesis. Cytogenet Genome Res 120(3–4):358–369. https://doi.org/10.1159/000121085Shalaby TA (2006) Embryogenesis and plantlets regeneration from anther culture of squash plants (Cucurbita pepo L.) as affected by different genotypes. J Agric Res Tanta Univ 32(1):173–183Song H, Lou QF, Luo XD, Wolukau JN, Diao WP, Qian CT, Chen JF (2007) Regeneration of doubled haploid plants by androgenesis of cucumber (Cucumis sativus L.). Plant Cell, Tissue Organ Cult 90(3):245–254. https://doi.org/10.1007/s11240-007-9263-ySteward FC, Mapes MO, Mears K (1958) Growth and organized development of cultured cells. II. Organization in cultures grown from freely suspended cells. Am J Bot 45(10):705–708Su YH, Zhao XY, Liu YB, Zhang CL, O’Neill SD, Zhang XS (2009) Auxin-induced WUS expression is essential for embryonic stem cell renewal during somatic embryogenesis in arabidopsis. Plant J 59(3):448–460. https://doi.org/10.1111/j.1365-313X.2009.03880.xSuprunova T, Shmykova N (2008) In vitro induction of haploid plants in unpollinated ovules, anther and microspore culture of Cucumis sativus. In: Cucurbitaceae 2008: proceedings of the IXth Eucarpia meeting on genetics and breeding of cucurbitaceae, pp 371–374Xie M, Qin L-Y, Pan J-S, He H-L, Wu A-Z, Cai R (2005) Flower morphogenesis and microspore development versus anther culture of cucumber. Acta Bot Boreal-Occid Sin 25(6):1096Zhan Y, Chen J-F, Malik AA (2009) Embryoid induction and plant regeneration of cucumber (Cucumis sativus L.) through microspore culture. Acta Hort Sin 36(2):221–22

    Extended tabu search-based scheduling to improve profitability in heterogeneous parallel systems

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    Higher utilization of existing resources and facilities in order to increase efficiency and profitability is always one of the basic challenges for parallel processing systems and environments, and this challenge becomes more complicated when the system resources are heterogeneous. One way to achieve high efficiency and profitability of heterogeneous parallel systems is to schedule tasks optimally. In this paper, an extended tabu search-based scheduling algorithm (ESTS) is presented to improve the profitability of heterogeneous parallel systems, which can achieve suitable solutions in a short computational time. To evaluate the efficiency of the proposed solution, due to the lack of a suitable criterion to evaluate this problem, the obtained results are compared with both the results of an extended scheduling based on a genetic algorithm (ESGA) with a large number of chromosomes and a high number of generations, as well as an extended scheduling based on a simulated annealing algorithm (ESSA) with a linear temperature reduction. The benchmark files of different sizes were tested under the same conditions, and the comparison of results shows the superiority of the proposed solution in terms of profitability and computational time

    Identification and tissue-specific expression of rutin biosynthetic pathway genes in Capparis spinosa elicited with salicylic acid and methyl jasmonate

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    Capparis spinosa is an edible medicinal plant which is considered as an excellent source of rutin. Rutin is a glycoside of the flavonoid quercetin that has been reported to have a beneficial role in controlling various diseases such as hypertension, arteriosclerosis, diabetes, and obesity. In this study, the partial cDNA of four genes involved in the rutin biosynthetic pathway including 4-coumaroyl CoA ligase (4CL), flavonoid 3'-hydroxylase (F3'H), flavonol synthase (FLS) and flavonol-3-O-glucoside L-rhamnosyltransferase (RT) were identified in C.spinosa plants for the first time. The protein sequences of these genes shared high similarity with the same proteins in other plant species. Subsequently, the expression patterns of these genes as well as rutin accumulation in C.spinosa leaves treated with different concentrations of salicylic acid (SA) and methyl jasmonate (MeJA) and also in different tissues of Caper plants treated with 100 mgL(-1) SA and 150 mu M MeJA were evaluated. The expression of all four genes was clearly up-regulated and rutin contents increased in response to MeJA and SA treatments after 24 h. The highest rutin contents (5.30 mgg(-1) DW and 13.27 mgg(-1) DW), as well as the highest expression levels of all four genes, were obtained using 100 mgL(-1) SA and 150 mu M MeJA, respectively. Among the different tissues, the highest rutin content was observed in young leaves treated with 150 mu M MeJA, which corresponded to the expression of related genes, especially RT, as a key gene in the rutin biosynthetic pathway. These results suggest that rutin content in various tissues of C. spinosa can be enhanced to a significant extent by MeJA and SA treatments and the gene expression patterns of rutin-biosynthesis-related genes are regulated by these elicitors

    Environmental Knowledge of and Training Methods for Physicians and Nurses of Pars-e-Jonoubi Company, Iran

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    Background & Objective: Having employees with appropriate environmental behaviors and paying attention to their environmental knowledge and training is an important issue especially for industrial companies. However, the lack of prioritization of this important issue is one of the effective factors in the declining trend of environmental performance improvement of industrial companies. Therefore, the main purpose of the present study was to evaluate the environmental knowledge of physicians and nurses working at Pars-e-Jonoubi Company, Iran, and propose appropriate methods for their environmental training. Methods: This research was a descriptive survey. The statistical population included all physicians and nurses working at Pars-e-Jonoubi Company, from among which 135 individuals were selected through random stratified sampling method and based on the Morgan Table. The data collection tool was a researcher-made environmental knowledge questionnaire based on the view of Frick et al. Data was analyzed using descriptive statistics, t, independent t, Friedman, and chi-square tests. Results: The knowledge of physicians and nurses, in their own view, regarding environmental systems was near average (3.1 and 3.3, respectively). Physicians’ and nurses’ knowledge on environmental action was near average (3.2), and below average (2.6), respectively. Their knowledge of effectiveness was higher than average (physicians: 3.8, nurses: 4.3). Generally, physicians estimated their environmental knowledge as slightly higher than average (3.6) and nurses as nearly average (3.2). Moreover, there was a significant difference between the average of the three aforementioned dimensions of their environmental knowledge and the criterion average. In addition, there was a significant difference between the average of the three dimensions of environmental knowledge of physicians and nurses. They also ranked environmental training methods differently. Descriptive statistics and chi-squared test showed that 76 subjects (61%) preferred the compulsive environmental training method and 48 subjects (39%) preferred the optional method. Conclusion: The results of this research indicated that physicians and nurses working at Pars-e-Jonoubi Company felt the need for obtaining, generally, more environmental knowledge, and specifically, more action-related knowledge. Thus, it is suggested that the necessary requirements be provided for the environmental training of physicians and nurses working at this company according to each group’s preferred training method. Key Words: Knowledge, Training, Environmen

    Optimal power flow incorporating facts devices and stochastic wind power generation using krill herd algorithm

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    © 2020 by the authors. This paper deals with investigating the Optimal Power Flow (OPF) solution of power systems considering Flexible AC Transmission Systems (FACTS) devices and wind power generation under uncertainty. The Krill Herd Algorithm (KHA), as a new meta‐heuristic approach, is employed to cope with the OPF problem of power systems, incorporating FACTS devices and stochastic wind power generation. The wind power uncertainty is included in the optimization problem using Weibull probability density function modeling to determine the optimal values of decision variables. Various objective functions, including minimization of fuel cost, active power losses across transmission lines, emission, and Combined Economic and Environmental Costs (CEEC), are separately formulated to solve the OPF considering FACTS devices and stochastic wind power generation. The effectiveness of the KHA approach is investigated on modified IEEE‐30 bus and IEEE‐57 bus test systems and compared with other conventional methods available in the literature

    Spectroscopic characteristics of Xeloda chemodrug

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    Introduction: Spectroscopic properties of Xeloda chemodrug have been studied over varying concentrations ranging between 0.001 and 10 mg/mL, using laser-induced fluorescence (LIF) spectroscopy. The alternative photoluminescence (PL) and near infrared (NIR) measurements are carried out to authenticate the obtained results by the LIF method.Methods: The XeCl laser as the excitation coherent source with 160 mJ/pulse at 308 nm is employed for LIF measurements of the fluorophore of interest in the modular spectroscopic set-up.Results: Xeloda as a significant chemodrug acts as a notable fluorophore. LIF, PL and NIR spectroscopy techniques are employed to investigate the spectral properties of the chemodrug in terms of concentration. The maximum LIF peak intensity of Xeloda is achieved at λmax=410.5 nm and the characteristic concentration of CP1=0.05 mg/mL. PL signals are in good agreement with the data given by the LIF measurements. The characteristic NIR spectra of Xeloda as solid evidence of chemical bonding formation attest to fluorescence quenching at the fluorophore concentration of ~ 0.2 mg/mL. Besides, the spectral shift of fluorescence signals which is obtained in terms of fluorophore concentration- demonstrating as a diagnostic marker for the purpose of optimized chemotherapy.Conclusion: Xeloda exhibits outstanding fluorescence properties over the allowable concentration in human serum (Cmax). These characteristics could benefit the potential advantage of simultaneous laser-based imaging of cell-chemodrug interaction over in-vivo studies. DOI: 10.34172/jlms.2021.5
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