Solution of viscous flow problems by using the boundary element method

A scheme based on the Boundary Element Method (BEM) for solving the problem of steady flow of an incompressible viscous fluid is presented in this thesis. The problem is governed by both Navier-Stokes (N-S) equations and the continuity equation. The fundamental solution of the two-dimensional N-S is derived, and the partial differential equations are converted to an integral equation;The computer code is flexible enough to handle a variety of boundary and domain elements with different degrees of interpolation polynomial. Boundary and domain integrals over corresponding elements are evaluated analytically. The Newton Raphson iteration scheme accompanied by a relaxation factor is used to solve the nonlinear equations. The code includes a post processor that calculates the velocity components at any point inside the domain;The scheme has been applied to three test problems. The first concerns Couette flow, which has been used as a test case for testing the rate of convergence and accuracy. The second and the third concern the driven cavity and the flow in a stepped channel, respectively;In the integral equation formulation, the primary unknowns are tractions on the domain boundary and velocities in the interior. Because the shear stress, drag, and lift can be simply computed from the values of tractions along the boundary, such a formulation is markedly superior to either the finite-difference or the finite-element formulation. In customary pressure-velocity or streamfunction-vorticity formulations, employed in the finite-difference or finite-element methods, calculation of stress, drag, and lift involves extensive postprocessing

Role of the Immune System and Bioactive Lipids in Trafficking Bone Marrow-Derived Stem Cells in Patients with Ischemic Heart Disease

Acute myocardial infarction (AMI) triggers the mobilization of stem/progenitor cells from bone marrow (BMSPCs) into peripheral blood (PB). The underlying mechanisms orchestrating this mobilization and subsequent homing of BMSPCs to the myocardium are poorly understood. While the role of traditional chemokines in the mobilization and homing of hematopoietic stem cell (HSCs) to BM niches is undisputed, their role in directing BMSPCs to the highly proteolytic environment of the ischemic myocardium is debatable and other redundant mechanism may exist. Based on our observation that bioactive lipids, such as sphingosine-1 phosphate (S1P) and ceramide-1 phosphate (C1P), play an important role in regulating trafficking of HSCs; we explored if they also direct trafficking of BMSPCs in the setting of myocardial ischemia. While BMSPCs expressed S1P receptors regardless of the source, the expression of S1P receptor 1 (S1PR1) and receptor 3 (S1PR3), which are responsible for migration and chemotaxis, was elevated in BMSPCs in naïve BM cells and was reduced following mobilization. This expression correlated to differential response of BMSPCs to S1P in chemotaxis assays. By employing flow cytometry analyses, we observed an increase in circulating PB CD34+, CD133+ and CXCR4+ lineage negative (Lin-)/CD45- cells that are enriched in non-HSCs (P \u3c 0.05 vs. controls). This corroborated our mass spectrometry studies showing a temporal increase in S1P and C1P plasma levels. At the same time, plasma obtained in the early phases following AMI strongly chemoattracted human BM-derived CD34+/Lin- and CXCR4+/Lin- cells in Transwell chemotaxis assays in an S1P dependent fashion. We examined other mechanisms that may contribute to the homing of BMSPCs to the infarcted myocardium due to the reduction of S1PRs upon mobilization. We observed that hypoxia induced higher expression of cathelicidins in cardiac tissues. Indeed, PB cells isolated from patients with AMI migrated more efficiently to low, yet physiological, gradient of SDF-1 in Transwell migration assays compared to SDF-1 alone. Together, these observations suggest that while elevated S1P plasma levels early in the course of AMI may trigger mobilization of non-HSCs into PB, cathelicidins appear to play an important role in their homing to ischemic and damaged myocardium

You Cannot Teach Writing – But You Can Provoke Talent

Panel: Teaching Writin

Parental Influence on Student Educational Expectations: Results from the 2012 Qatar Education Study

This study investigated factors that are likely to influence students’ educational expectations in the State of Qatar, concentrating on selected parental factors. Drawing on recent work in the field, the study examined the intersection of student demographic and socio-economic attributes along with contextual factors, on student educational expectations. The study uses student and parent data from a nation-wide survey of preparatory and secondary schools, the 2012 Qatar Education Study. The results showed students’ gender and grade level positively affect their reported educational expectations, with females and those in higher grade levels more likely to report higher expectations. While student reports of parental involvement were not significant, parent reports were marginally significant. The paper concludes with some recommendations for further study and research

The Onset of Chaos in Pulsating Variable Stars

Random changes in pulsation period occur in cool pulsating Mira variables, Type A, B, and C semiregular variables, RV Tauri variables, and in most classical Cepheids. The physical processes responsible for such fluctuations are uncertain, but presumably originate in temporal modifications of the envelope convection in such stars. Such fluctuations are seemingly random over a few pulsation cycles of the stars, but are dominated by the regularity of the primary pulsation over the long term. The magnitude of stochasticity in pulsating stars appears to be linked directly to their dimensions, although not in simple fashion. It is relatively larger in M supergiants, for example, than in short-period Cepheids, but is common enough that it can be detected in visual observations for many types of pulsating stars. Although chaos was discovered in such stars 80 years ago, detection of its general presence in the group has only been possible in recent studies.Comment: To appear in the proceedings of the Odessa Variable Stars 2010 Conference (see http://uavso.org.ua/?page=vs2010&lang=en), edited by I. Andronov and V. Kovtyuk

Perovskite Strontium Doped Rare Earth Manganites Nanocomposites and Their Photocatalytic Performances

Studying catalysts in situ is an important topic that helps us to understand their surface structure and electronic states in operation. Three types of materials are used in the degradation of organic matter, which has applications in the environmental remediation and self -cleaning surfaces. The technique is widely known but still hampered by one significant limitation. The materials generally absorb ultra violet UV light but we need to develop active materials for visible light. Utilizing the sunlight efficiently for solar energy conversion is an important demand in the present time. The research on visible-light active photocatalysts attracted a lot of interest. The perovskite-like compounds are found to be active catalysts for the oxidation of carbon monoxide. In the present chapter, we will focus on the application of the nano-sized strontium doped neodymium manganites within perovskite like structure as photocatalysis and studying their photocatalytic performance