84 research outputs found

    Comparing the effect of lecture and rescue training methods with the war maneuvers on the public aid preparedness in the personnel of the navy's military barracks

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    Aims: Simulation is one of active learning techniques that learners are encouraged to acquire skills and knowledge. This study aimed to determine comparing the effect of lecture and rescue training methods with the war maneuvers on the public aid preparedness in the personnel of the navy's military barracks in 2014. At first, Kolmogorov Smirnov test was used to detect normal data, and independent t-test was performed for normal data, and Mann-Whitney and Wilcoxon tests were used for non-normal data to examine the proposal. Methods: This research was a quasi-experimental study. 132 military personnel were selected by stratified sampling and divided identically in two groups into lectures and training along with combat maneuvers. Multiple-choice test made by researcher was used to determine the level of knowledge before and after the intervention. After gathering information and bringing them into the SPSS software, version 19, data were analyzed using descriptive statistics (Mean and Standard deviation) and inferential statistics. Results: The mean score of the subjects before and after intervention was obtained 12.81 ± 3 and 20.59 ± 3.34, respectively. The results of the comparison between the two groups before and after intervention showed that there were significant differences both lectures and practical groups (P <0.001). Moreover, both groups after intervention indicated an increased score, but the score of operation group increased more than lecture group. Conclusion: The practical training of military forces with war maneuvers has more impact than lecture training method on the amount of preparation and rescue. It is recommended to be used practical training method of military forces along with war maneuvers for military preparedness

    Evaluation of the Effect of Geomechanical Parameters and In Situ Stress on Tunnel Response Using Equivalent Mohr-Coulomb and Generalized Hoek-Brown Criteria

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    The generalized Hoek-Brown (GHB) failure criterion can estimate the rock mass parameters required for rock mechanics–related analyses such as numerical modeling in geomechanics. The determination of GHB parameters has been developed in the field of rock mechanics. Due to the wide use of the Mohr-Coulomb criterion and the lack of an existing relationship for determining its parameters for a rock mass, equivalent Mohr-Coulomb parameters (EMC) can be derived from the GHB. To determine the differences in the use of these two criteria, we analyzed the behavior of a deep circular tunnel in nine stress states for three metamorphic rocks recovered from the Canadian Shield from rock masses that present a very blocky structure. We carried out 241 simulations using the finite element code RS2 to assess the effect of the geological strength index (GSI), in situ stress, and rock type on the deviation of wall displacement, the number of yielded elements, and the differential stress obtained by the GHB and EMC parameters. A combination of low in situ stress and high GSI yielded similar results when using both failure criteria

    Computational, experimental details, and biological raw data accompanying the publication: “The synthesis and characterization of a nanomagnetite with potent antibacterial activity and low mammalian toxicity”

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    This data file includes experimental details on how to make uncoated iron oxide nanoparticles using a green electrochemical method. It provides the raw data on the antibacterial activity of one of these formulations, and the full computational data and methodology used to generate that data, of several different magnetite clusters of specific spin multiplicities for 4, 5, 7 and 9 iron atom magnetite clusters. This data will assist other researchers wishing to replicate or expand on these results for the investigation and use of nanomagnetite for antibacterial applications

    The synthesis and characterization of a magnetite nanoparticle with potent antibacterial activity and low mammalian toxicity

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    Magnetite has shown some promise as a biomedical material and antibacterial agent; however the benefits are normally only realized when it is used in combination with other metals or drugs. Unfunctionalized magnetite may be a biocompatible alternative. This report discusses the synthesis and potent antibacterial activity, with low associated mammalian organ toxicity, of nanomagnetite particles. Magnetite (Fe3O4) nanoparticles were electrochemically prepared in a green surfactant-free, closed water loop system. These materials, characterized by X-ray diffraction, FTIR, and vibrational magnetometry, also appear contaminated with Fe-O-O-H functionalities. This physical characterization is accompanied by a computational investigation of truncated clusters showing that a magnetite-derived cluster of 7 iron atoms is a sufficient model to generate the vibrational frequencies experimentally observed in magnetite using DFT calculations. The nanoparticles, evaluated for antibiotic activity, were shown to have minimum inhibitory concentrations of 2.8 and 2.0 μg/mL against E. coli and S. aureus respectively. This is both a 100-fold lower concentration than the human cytotoxic dose determined by an MTT assay and is also comparable to the effective dose of traditional antibiotics. A dose-dependent decrease in catalase activity and an increase in the levels of lipid peroxidation suggests that these nanoparticles act through damaging the anti-oxidant systems in cells. However, renal and hepatic damage was only observed at daily doses (2 weeks) of 100 μg/mL and higher. This significant therapeutic window suggests that these materials might prove useful as potential complementary therapeutics in the future

    The Correlation between Serum Levels of Anti-Toxoplasma gondii Antibodies and the Risk of Diabetes

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    Background: This study investigated the presence of specific antibodies against Toxoplasma gondii infection among people with diabetes (type I and II) in comparison with control group. Methods: Overall 300 serum samples were collected equally from three groups including patients with type I and type II diabetes and non-diabetic healthy control that referred to Tabriz Central Laboratory in northwest Iran during July to Sep 2015. The level of specific IgG and IgM antibodies against T. gondii were measured using the chemiluminescence immunoassay (CLIA) method. Chi-square and One-Way ANCOVA were used for data analysis. Results: Overall, 300 samples from diabetic patients (type I and type II) and control group were examined and results showed 3, 8 and 2 cases were seropositive for anti- T. gondii IgM respectively. Anti- T. gondii IgG seropositivity in type I and type II diabetes and control groups were 69%, 63% and 59% respectively. We did not observe any statistical differences among all studied groups in terms of toxoplasmosis. There was no statistically significant relationship between all variables and seropositivity for anti-T. gondii antibodies in type I and II diabetes and non-diabetic groups. Conclusion: Although there was no statistically significant relationship between diabetes and toxoplasmosis further investigations especially experimental studies using animal models are needed. Furthermore, these findings would not be contrary to the need for healthcare in order to the prevention of infectious disease in diabetic patients

    Association study of Interleukin 10 gene polymorphisms in Iraqi patients with multiple sclerosis

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    Multiple sclerosis (MS) is a type of autoimmune disease where immune cell attacks our cells mistakenly; its severity is measured by expanded disease status scale (EDSS). The study aims the investigation of −1082 polymorphism in interleukin 10 (IL-10) as one of the etiologies that develops the disease. This is a case-control study that allele-specific polymerase chain reaction (AS-PCR) were provided to compare 100 relapsing-remitting MS (RRMS) patients, which fulfills McDonald criteria with 100 healthy controls depending on the −1082 (G/A) polymorphism of the gene encoding IL-10. The A allele frequency of IL-10 gene has been considerably less in MS patients compare to healthy control (60.50 Vs. 81%). Genotype distributions of the single nucleotide polymorphism (SNP) -1082 fulfills Hardy-Weinberg equilibrium in cases (P = 0.155) but it doesn't in controls (P < 0.0001). In MS patients, Heterozygous (GA) genotypes were non-significantly associated with MS (OR = 0.834,95% CI = 0.6890 to 1.29, P 0.706) but homozygous (AA) were significantly associated with this condition (OR = 3.420, 95% CI = 1.450 to 8.065, P = 0.0037). To conclude, the genotype distribution of −1082 (G/A) polymorphism has been showed a significant difference in the case/control study recruited in Erbil province-Iraq, and EDSS is significantly higher in A allele's carrier genotypes. There was non-significance association AA genotypes and duration of the disease

    SiO2 nanoparticle and KCl salt effects on filtration and thixotropical behavior of polymeric water based drilling fluid: With zeta potential and size analysis

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    Maturity of conventional and shallow reserves and demand of energy force the drilling industry to drill deeper and more complicated wells. The nanoparticles initiated revolution in different aspects of science and engineering. Utilizing these particles can lead to a more efficient drilling in deep and troublesome environments. In this study the polymeric water based drilling fluid was set as base fluid. Effects of SiO2 nanoparticles and KCl salt on different aspects of polymeric water based drilling fluid filtration and thixotropical behavior in different concentrations and temperatures were investigated. Mostly, the SiO2 nanoparticle addition improved the drilling fluid performance however, the addition of SiO2 nanoparticles in higher concentrations was not so effective. The concentration of SiO2 nanoparticles for effective and justifiable usage should be carefully selected. The KCl also had impact on SiO2 nanoparticles behavior in drilling fluid. It is shown by measuring zeta potential and particles size, the SiO2 nanoparticles in different temperatures, SiO2 and KCl concentrations have different properties. The high KCl concentration affected the effectiveness of SiO2 nanoparticles in filtration behavior improvement. Moreover, presence of KCl changed the thixotropical behavior of SiO2 contained drilling fluid. Keywords: Nanofluid, Drilling fluid, Filtration, Thixotropy, SiO2 nanoparticl

    Comparative survey on scolicidal effects of selenium and silver nanoparticles on protoscolices of hydatid cyst

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    Hydatidosis is a zoonotic diseases which affects human and livestock animals. The surgical treatment of hydatid diseases in man is still the most effective approach, but spillage of protoscolices is the risk of surgery. Therefore, it is essential to develop alternative approaches. Injection of protoscolicidal agents into the cysts preoper¬atively is an alternative method.The aim of the present study was the determination and comparison of lethal effects of silver nanoparticles (Ag-NPs) and selenium nanoparticles (Se-NPs) on protoscolices of hydatid cyst. Livers and lungs of sheep, which was naturally infected by hydatid cyst were collected from Tabriz slaughterhouse and transferred to the parasitology laboratory. Initially, the surface of cysts was disinfected by 70% Alcohol. Then, 25 ml of each cyst fluid were aspirated by sterile syringe and transferred to Erlenmeyer flask. After 30 minutes, the supernatant was discarded and protoscolices were washed with phosphate-buffered saline and tested by 1% eosin to assess their viability. Next, the samples of protoscolices, which were over 90%, were selected and the effect of 50, 125, 250 and 500 (µg/ml) of Se-NPs and Ag-NPs in the exposure times of 10, 20, 30 and 60 min were evaluated. Data were analysed by SAS software and analyzed by Duncan's comparison test. The significant differences were considered to be p<0.0001.The difference between the scolicidal effects of Se-NPs was statistically significant for all examined concentrations and exposure times compared to the control group (p<0.0001). On the other hand, the scolicidal effect of Ag-NPs in 10 and 20 min exposer was not significant in comparison to the control group. Overall scolicidal effect of Se-NPs was higher than Ag-NPs and the difference was significant (p<0.0001).The results of the present research indicated that it is possible to use Se-NPs as an effective scolicidal treatment. It is suggested the study of employing this compound in vivo or in combination with other procedures in treating hydatid cyst in further studies
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