205 research outputs found
Weakly Interacting Bose Mixtures at Finite Temperature
Motivated by the recent experiments on Bose-Einstein mixtures with tunable
interactions we study repulsive weakly interacting Bose mixtures at finite
temperature. We obtain phase diagrams using Hartree-Fock theory which are
directly applicable to experimentally trapped systems. Almost all features of
the diagrams can be characterized using simple physical insights. Our work
reveals two surprising effects which are dissimilar to a system at zero
temperature. First of all, no pure phases exist, that is, at each point in the
trap, particles of both species are always present. Second, even for very weak
interspecies repulsion when full mixing is expected, condensate particles of
both species may be present in a trap without them being mixed.Comment: 4 pages, 2 figure
Binary Bose-Einstein Condensate Mixtures in Weakly and Strongly Segregated Phases
We perform a mean-field study of the binary Bose-Einstein condensate mixtures
as a function of the mutual repulsive interaction strength. In the phase
segregated regime, we find that there are two distinct phases: the weakly
segregated phase characterized by a `penetration depth' and the strongly
segregated phase characterized by a healing length. In the weakly segregated
phase the symmetry of the shape of each condensate will not take that of the
trap because of the finite surface tension, but its total density profile still
does. In the strongly segregated phase even the total density profile takes a
different symmetry from that of the trap because of the mutual exclusion of the
condensates. The lower critical condensate-atom number to observe the complete
phase segregation is discussed. A comparison to recent experimental data
suggests that the weakly segregated phase has been observed.Comment: minor change
Topology of the ground state of two interacting Bose-Einstein condensates
We investigate the spatial patterns of the ground state of two interacting
Bose-Einstein condensates. We consider the general case of two different atomic
species (with different mass and in different hyperfine states) trapped in a
magnetic potential whose eigenaxes can be tilted with respect to the vertical
direction, giving rise to a non trivial gravitational sag. Despite the
complicated geometry, we show that within the Thomas-Fermi approximations and
upon appropriate coordinate transformations, the equations for the density
distributions can be put in a very simple form. Starting from this expressions
we give explicit rules to classify the different spatial topologies which can
be produced, and we discuss how the behavior of the system is influenced by the
inter-atomic scattering length. We also compare explicit examples with the full
numeric Gross-Pitaevskii calculation.Comment: RevTex4, 8 pages, 7 figure
Macroscopic quantum tunneling of two-component Bose-Einstein condensates
We show theoretically the existence of a metastable state and the possibility
of decay to the ground state through macroscopic quantum tunneling in
two-component Bose-Einstein condensates with repulsive interactions. Numerical
analysis of the coupled Gross-Pitaevskii equations clarifies the metastable
states whose configuration preserves or breaks the symmetry of the trapping
potential, depending on the interspecies interaction and the particle number.
We calculate the tunneling decay rate of the metastable state by using the
collective coordinate method under the WKB approximation. Then the height of
the energy barrier is estimated by the saddle point solution. It is found that
macroscopic quantum tunneling is observable in a wide range of particle
numbers. Macroscopic quantum coherence between two distinct states is
discussed; this might give an additional coherent property of two-component
Bose condensed systems. Thermal effects on the decay rate are estimated.Comment: 11 pages, 10 figures, revtex
Observation of metastable states in spinor Bose-Einstein condensates
Bose-Einstein condensates have been prepared in long-lived metastable excited
states. Two complementary types of metastable states were observed. The first
is due to the immiscibility of multiple components in the condensate, and the
second to local suppression of spin-relaxation collisions. Relaxation via
re-condensation of non-condensed atoms, spin relaxation, and quantum tunneling
was observed. These experiments were done with F=1 spinor Bose-Einstein
condensates of sodium confined in an optical dipole trap.Comment: 3 figures included in paper, fourth figure separat
10 simple rules to create a serious game, illustrated with examples from structural biology
Serious scientific games are games whose purpose is not only fun. In the
field of science, the serious goals include crucial activities for scientists:
outreach, teaching and research. The number of serious games is increasing
rapidly, in particular citizen science games, games that allow people to
produce and/or analyze scientific data. Interestingly, it is possible to build
a set of rules providing a guideline to create or improve serious games. We
present arguments gathered from our own experience ( Phylo , DocMolecules ,
HiRE-RNA contest and Pangu) as well as examples from the growing literature on
scientific serious games
Spinor condensates and light scattering from Bose-Einstein condensates
These notes discuss two aspects of the physics of atomic Bose-Einstein
condensates: optical properties and spinor condensates. The first topic
includes light scattering experiments which probe the excitations of a
condensate in both the free-particle and phonon regime. At higher light
intensity, a new form of superradiance and phase-coherent matter wave
amplification were observed. We also discuss properties of spinor condensates
and describe studies of ground--state spin domain structures and dynamical
studies which revealed metastable excited states and quantum tunneling.Comment: 58 pages, 33 figures, to appear in Proceedings of Les Houches 1999
Summer School, Session LXXI
Formation, dynamics and stability of coreless vortex dipoles in phase-separated binary condensates
We study the motion of the Gaussian obstacle potential created by blue
detuned laser beam through a phase-separated binary condensate in
pancake-shaped traps. For the velocity of the obstacle above a critical
velocity, we observe the generation of vortex dipoles in the outer component
which can penetrate the inner component. This is equivalent to finite, although
small, transport of outer component across the inner component. In the inner
component, the same method can lead to the formation of coreless vortex
dipoles.Comment: 12 pages, 9 figure
FUS/TLS Is a Co-Activator of Androgen Receptor in Prostate Cancer Cells
Androgen receptor (AR) is a member of the nuclear receptor family of transcription factors. Upon binding to androgens, AR becomes transcriptionally active to regulate the expression of target genes that harbor androgen response elements (AREs) in their promoters and/or enhancers. AR is essential for the growth and survival of prostate cancer cells and is therefore a target for current and next-generation therapeutic modalities against prostate cancer. Pathophysiologically relevant protein-protein interaction networks involving AR are, however, poorly understood. In this study, we identified the protein FUsed/Translocated in LipoSarcoma (FUS/TLS) as an AR-interacting protein by co-immunoprecipitation of endogenous proteins in LNCaP human prostate cancer cells. The hormonal response of FUS expression in LNCaP cells was shown to resemble that of other AR co-activators. FUS displayed a strong intrinsic transactivation capacity in prostate cancer cells when tethered to basal promoters using the GAL4 system. Chromatin immunoprecipitation experiments showed that FUS was recruited to ARE III of the enhancer region of the PSA gene. Data from ectopic overexpression and âknock-downâ approaches demonstrated that AR transcriptional activity was enhanced by FUS. Depletion of FUS reduced androgen-dependent proliferation of LNCaP cells. Thus, FUS is a novel co-activator of AR in prostate cancer cells
Monitoring county-level chlamydia incidence in Texas, 2004 â 2005: application of empirical Bayesian smoothing and Exploratory Spatial Data Analysis (ESDA) methods
<p>Abstract</p> <p>Background</p> <p>Chlamydia continues to be the most prevalent disease in the United States. Effective spatial monitoring of chlamydia incidence is important for successful implementation of control and prevention programs. The objective of this study is to apply Bayesian smoothing and exploratory spatial data analysis (ESDA) methods to monitor Texas county-level chlamydia incidence rates by examining spatiotemporal patterns. We used county-level data on chlamydia incidence (for all ages, gender and races) from the National Electronic Telecommunications System for Surveillance (NETSS) for 2004 and 2005.</p> <p>Results</p> <p>Bayesian-smoothed chlamydia incidence rates were spatially dependent both in levels and in relative changes. Erath county had significantly (p < 0.05) higher smoothed rates (> 300 cases per 100,000 residents) than its contiguous neighbors (195 or less) in both years. Gaines county experienced the highest relative increase in smoothed rates (173% â 139 to 379). The relative change in smoothed chlamydia rates in Newton county was significantly (p < 0.05) higher than its contiguous neighbors.</p> <p>Conclusion</p> <p>Bayesian smoothing and ESDA methods can assist programs in using chlamydia surveillance data to identify outliers, as well as relevant changes in chlamydia incidence in specific geographic units. Secondly, it may also indirectly help in assessing existing differences and changes in chlamydia surveillance systems over time.</p
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