From autoantibody research to standardized diagnostic assays in the management of humen diseases : Report on the 12th Dresden Symposium on Autoantibodies September 23–26, 2015

Item does not contain fulltext432 p

From autoantibody research to standardized diagnostic assays in the management of human diseases - report of the 12th Dresden Symposium on Autoantibodies

Item does not contain fulltex

Effects Of Cigarette Smoke Inhalation And Coffee Consumption On Bone Formation And Osseous Integration Of Hydroxyapatite Implant [os Efeitos Do Cigarro E Do Consumo De Café Sobre A Formação óssea E A Integração óssea De Implantes De Hidroxiapatita]

The present study aims to assess the effects of cigarette smoke inhalation and/or coffee consumption on bone formation and osseous integration of a dense hydroxyapatite (D.HA) implant in rats. For this study, 20 male rats were divided into four groups (n = 5): C.T (control) group, C.E (coffee) group, C.I (cigarette) group and C.C (coffee + cigarette) group. During 16 weeks, animals in the C.I group were exposed to cigarette smoke inhalation equivalent to 6 cigarettes per day; specimens in the C.E group drank coffee as liquid diet; and rats in the C.C group were submitted to both substances. In the 6th week a 5 mm slit in the parietal bone and a 4 mm slit in the tibia were performed on the left side: the former was left open while the latter received a D.HA implant. As soon as surgeries were finished, the animals returned to their original protocols and after 10 weeks of exposure they were euthanised (ethically sacrificed) and the mentioned bones collected for histological processing. Data showed that exposure to cigarette smoke inhalation and coffee consumption did not interfere in weight gain and that solid and liquid diet consumption was satisfactory. Rats in the C.C group showed a decrease in bone neoformation around the tibial D.HA implant (31.8 ± 2.8) as well as in bone formation in the parietal slit (28.6 ± 2.2). On their own, cigarette smoke inhalation or coffee consumption also led to diminished bone neoformation around the implant and delayed the bone repair process in relation to the C.T group. However, reduction in the bone repair process was accentuated with exposure to both cigarette smoke inhalation and coffee consumption in this study.731173177Tipo de preparo de café, , http://www.abic.com.br, Associação Brasileira da Indústria do Café-ABIC. Available from: Access in: 10 June 2007Alves, R.C., Casal, S., Oliveira, B., Benefícios do café na saúde: Mito ou realidade? (2009) Quimica Nova, 32 (8), pp. 2169-2180. , http://dx.doi.org/10.1590/S0100-40422009000800031Araujo, F.A., (2007) Café (Coffea arabica L.) submetido a diferentes torrefações: Caracterização química e avaliação da atividade antioxidante e sensorial., p. 157. , São Paulo: Universidade de São Paulo. Tese de Doutorado em Nutrição ExperimentalBenatti, B.B., César-Neto, J.B., Gonçalves, P.F., Sallum, E.A., Nociti, F.H., Smoking affects the self-healing capacity of periodontal tissues. A histological study in the rat (2005) European Journal of Oral Science, 113 (5), pp. 400-403. , http://dx.doi.org/10.1111/j.1600-0722.2005.00240.xBueno, A.C., Ribeiro, K.G., Cruz, T.M., Ivo, T.P.F., Santos, A.M.M., Camilli, J.A., Garcia, J.A.D., Soares, E.A., Efeitos da fumaça de cigarro sobre a osteogênese e a resistência mecânica óssea em ratos (2011) Revista de Ciência Farmacêutica Básica Aplicada, 32 (1)Felipe, L., Simões, L.C., Gonçalves, D.U., Mancini, P.C., Avaliação do efeito da cafeína no teste vestibular (2005) Revista Brasileira Otorrinolaringologia, 71 (6), pp. 758-762. , http://dx.doi.org/10.1590/S0034-72992005000600012Froes, N.D.T.C., Pereira, E.S., Negrelli, W.F., Fatores de risco da osteoporose: Prevenção e detecção através do monitoramento clínico e genético (2002) Acta Ortopédica. Brasileira, 10 (1), pp. 52-56Heaney, R.P., Effects of caffeine on bone and the calcium economy (2002) Food and Chemical Toxicology, 40 (9), pp. 1263-1270. , http://dx.doi.org/10.1016/S0278-6915(02)00094-7Kapoor, D., Jones, T.H., Smoking and hormones in health and endocrine disorders (2005) European Journal of Endocrinology, 152 (4), pp. 491-499. , http://dx.doi.org/10.1530/eje.1.01867Lacerda, S.A., Matuoka, R.I., McEdo, R.M., Petenusci, S.O., Campos, A.A., Brentegani, L.G., Bone quality associated with daily consumption of coffee: A biochemical, radiographic and histometric study (2010) Brazilian Dental Journal, 21 (3), pp. 199-204. , http://dx.doi.org/10.1590/S0103-64402010000300004Lima, C.C., Silva, T.D., Santos, L., Nakagaki, W.R., Loyola, Y.C.S., Resck, M.C.C., Camilli, J.A., Garcia, J.A.D., Effects of ethanol on the osteogenesis around porous hydroxyapatite implants (2011) Brazilian Journal of Biology, 71 (1), pp. 115-119. , http://dx.doi.org/10.1590/S1519-69842011000100017Lloyd, T., Rollings, N., Eggli, D.F., Kieselhorst, K., Chinchilli, V.M., Dietary caffeine consumption and bone status of postmenopausal women (1997) American Journal of Clinical Nutrition, 65, pp. 1826-1830Mandarim-De-Lacerda, C.A., What is the interest of normal and pathological morphological research to be quantitative? The exemple of the stereology (1999) Brazilian Journal of Morphological, 16 (2), pp. 131-139Marks, S.C., Popoff, S.N., Bone cell biology: The regulation of development, structure, and function in the skeleton (1988) American Journal of Anatomy, 183 (1), pp. 2-44Nehlig, A., (2004) Coffee, Tea, Chocolate, and the Brain, , http://dx.doi.org/10.1201/9780203618851, Boca Raton: CRC Press LLCNociti Jr., F.H., César, N.J., Carvalho, M.D., Sallum, E.A., Bone density around titanium implants may be influenced by intermittent cigarette smoke inhalation-A histometric study in rats (2002) International Journal of Oral and Maxillofacial Implants, 17 (3), pp. 347-352Pinto, N.A.V.D., (2002) Avaliação química e sensorial de diferentes padrões de bebida do café arábica cru e torrado., p. 92. , Lavras: Universidade Federal de Lavras. Tese de doutorado em Ciência dos AlimentosPlaneta, C.S., Cruz, F.C., Bases neurofisiológicas da dependência do tabaco (2005) Revista de Psiquiatria Clínica, 32 (5), pp. 251-258Sakakura, C.E., Marcantonio Jr., E., Rezende, M.L.R., O efeito do tabagismo na implantodontia (2001) BCI, 8 (32), pp. 276-280Sakamoto, W., Nishihira, J., Fujie, K., Iizuka, T., Handa, H., Ozaki, M., Yukawa, S., Effect of coffee consumption on bone metabolism (2001) Bone, 28 (3), pp. 332-336. , http://dx.doi.org/10.1016/S8756-3282(00)00444-0Soares, E.A., Favaro, W.J., Cagnon, V.H.A., Bertran, C.A., Camilli, J.A., Effects of alcohol and nicotine on the mechanical resistance of bone and bone neoformation around hydroxyapatite implants (2010) Journal of Bone Mineral Metabolism, 28 (1), pp. 101-107. , http://dx.doi.org/10.1007/s00774-009-0115-1Svendsen, P., Hau, J., (1984) Handbook of laboratory animal science, 1. , Boca Raton: CRC PressTsuang, Y.H., Sun, J.S., Chen, L.T., Sun, S.C., Chen, S.C., Direct effects of caffeine on osteoblastic cells metabolism: The possible causal effect of caffeine on the formation of osteoporosis (2006) Journal of Orthopaedic Surgery, 1, p. 7. , http://dx.doi.org/10.1186/1749-799X-1-7(1993) The ICD-10 classification of mental and behavioural disorders: Diagnostic criteria for research., , World Health Organization-WHO, Geneva: WH

Acúmulo de nutrientes e matéria seca na parte aérea de dois cultivares de soja RR sob efeito de formulações de glyphosate Nutrient and shoot dry matter accumulation of two GR soybean cultivars under the effect of glyphosate formulations

O estudo da seletividade e dos efeitos secundários dos herbicidas nas culturas agrícolas é de extrema importância para o sucesso da agricultura. Objetivou-se com este trabalho avaliar o efeito de formulações de glyphosate sobre o acúmulo de nutrientes e produção de matéria seca na parte aérea de dois cultivares de soja resistente ao glyphosate (RR). O experimento foi conduzido em casa de vegetação, em delineamento de blocos ao acaso com seis repetições. Os tratamentos resultaram do arranjo fatorial entre formulações de glyphosate (Roundup Original®, Roundup Ready®, Roundup Transorb®, Roundup WG®, Roundup Ultra® e Zapp Qi®), mais uma testemunha e cultivares de soja RR (CD 225 RR e V Max RR). As aplicações dos herbicidas ocorreram quando as plantas se apresentavam no estádio V3, na dosagem de 960 g e.a. ha-1. O acúmulo de macronutrientes e micronutrientes e a produção de matéria seca na parte aérea das plantas sempre foram maiores no cultivar V Max RR em relação ao CD 225 RR. As formulações Roundup Ready® e Roundup Ultra® não proporcionaram redução no acúmulo de nutrientes e na produção de matéria seca na parte aérea dos cultivares. Por sua vez, Roundup Transorb®, Roundup Original® e Roundup WG® prejudicaram a nutrição dos cultivares e a produção de matéria seca. Conclui-se que o acúmulo de nutrientes e a produção de matéria seca na parte aérea de plantas de soja são alterados em função da aplicação de glyphosate, mesmo para cultivares RR.<br>The study of selectivity and secondary effects of herbicides on crops is extremely important to successful agriculture. This research aimed to evaluate the effect of glyphosate formulations on nutrient accumulation and dry matter production on the shoot of two glyphosateresistant (GR) soybean cultivars. The assay was carried out in a greenhouse and arranged in a randomized complete block design, replicated six times. The treatments were in a factorial arrangement including six glyphosate formulations (Roundup Original®, Roundup Ready®, Roundup Transorb®, Roundup WG®, Roundup Ultra® and Zapp Qi®), plus a control treatment, and two soybean cultivars (CD 225 RR and V Max RR). The herbicide applications were performed when the plants were at the V3 growth stage, using a dose of960 g a.e. ha-1 . The macronutrient and micronutrient accumulation and dry matter production in the shoot of the soybean plants were greater in V Max RR cultivar than in CD 225 RR cultivar. The formulations Roundup Ready® and Roundup Ultra® did not promote nutrient accumulation reduction in the shoot ofthe cultivars. In addition, the formulations Roundup Original®, Roundup Transorb® and Roundup WG® caused the greatest damage to nutrient accumulation and dry matter production. It was concluded that nutrient accumulation and dry matter production in the shoots of the soybean plants are affected by glyphosate application, even for GR cultivars