Unclassified autoimmune pancreatitis mimicking pancreatic cancer

A 24-year-old black male presented with a 1-week obstructive jaundice and intermittent abdominal pain, with no significant weight loss and an unsuspicious abdominal exam. Blood chemistry showed a cholestatic pattern but a complete immunological and tumoral panel (anti-smooth muscle antibody, anti-mitochondrial antibody, anti-nuclear antibody, anti-neutrophil cytoplasmic antibody, anti-Smith, anti-double-stranded-DNA antibody (anti-dsDNA), complement C3/C4, carcinoembryonic antigen, CA 19-9 and IgG4) were all within normal limits. Abdominal ultrasound revealed dilatation of the intra and extra-hepatic bile ducts. CT scan showed an abnormal dilatation of the distal bile duct but no focal enlargement of the head of the pancreas. Endoscopic ultrasound suggested an inflammatory process but the magnetic resonance cholangio-pancreatography favored a neoplastic obstruction of the distal common bile duct. Fine-needle aspiration cytology was insufficient for definitive diagnosis and the patient underwent major surgery. Follow-up with mild exocrine pancreatic insufficiency treated with enzyme replacement.info:eu-repo/semantics/publishedVersio

Gravitational collapse of the OMC-1 region

We have investigated the global dynamical state of the Integral Shaped Filament in the Orion A cloud using new N$_2$H$^+$ (1-0) large-scale, IRAM30m observations. Our analysis of its internal gas dynamics reveals the presence of accelerated motions towards the Orion Nebula Cluster, showing a characteristic blue-shifted profile centred at the position of the OMC-1 South region. The properties of these observed gas motions (profile, extension, and magnitude) are consistent with the expected accelerations for the gravitational collapse of the OMC-1 region and explain both the physical and kinematic structure of this cloud.Comment: 5 pages, 2 figures; Accepted by A&

Detection of Point Sources in Cosmic Ray Maps using the Mexican Hat Wavelet Family

An analysis of the sensitivity of gaussian and mexican hat wavelet family filters to the detection of point sources of ultra-high energy cosmic rays was performed. A source embedded in a background was simulated and the number of events and amplitude of this source was varied aiming to check the sensitivity of the method to detect faint sources with low statistic of events.Comment: Proceedings of the Second International Symposium on Strong Electromagnetic Fields and Neutron Stars (Havana, Cuba, 2011). 6 pages, 4 figure

Helix Formation and Folding in an Artificial Peptide

We study the relation between $\alpha$-helix formation and folding for a simple artificial peptide, Ala$_{10}$-Gly$_5$-Ala$_{10}$. Our data rely on multicanonical Monte Carlo simulations where the interactions among all atoms are taken into account. The free-energy landscape of the peptide is evaluated for various temperatures. Our data indicate that folding of this peptide is a two-step process: in a first step two $\alpha$-helices are formed which afterwards re-arrange themselves into a U-like structure.Comment: 15 pages, with 9 eps figure

Exact solution for the energy density inside a one-dimensional non-static cavity with an arbitrary initial field state

We study the exact solution for the energy density of a real massless scalar field in a two-dimensional spacetime, inside a non-static cavity with an arbitrary initial field state, taking into account the Neumann and Dirichlet boundary conditions. This work generalizes the exact solution proposed by Cole and Schieve in the context of the Dirichlet boundary condition and vacuum as the initial state. We investigate diagonal states, examining the vacuum and thermal field as particular cases. We also study non-diagonal initial field states, taking as examples the coherent and Schrodinger cat states.Comment: 10 pages, 8 figure

Electron-scale shear instabilities: magnetic field generation and particle acceleration in astrophysical jets

Strong shear flow regions found in astrophysical jets are shown to be important dissipation regions, where the shear flow kinetic energy is converted into electric and magnetic field energy via shear instabilities. The emergence of these self-consistent fields make shear flows significant sites for radiation emission and particle acceleration. We focus on electron-scale instabilities, namely the collisionless, unmagnetized Kelvin-Helmholtz instability (KHI) and a large-scale dc magnetic field generation mechanism on the electron scales. We show that these processes are important candidates to generate magnetic fields in the presence of strong velocity shears, which may naturally originate in energetic matter outburst of active galactic nuclei and gamma-ray bursters. We show that the KHI is robust to density jumps between shearing flows, thus operating in various scenarios with different density contrasts. Multidimensional particle-in-cell (PIC) simulations of the KHI, performed with OSIRIS, reveal the emergence of a strong and large-scale dc magnetic field component, which is not captured by the standard linear fluid theory. This dc component arises from kinetic effects associated with the thermal expansion of electrons of one flow into the other across the shear layer, whilst ions remain unperturbed due to their inertia. The electron expansion forms dc current sheets, which induce a dc magnetic field. Our results indicate that most of the electromagnetic energy developed in the KHI is stored in the dc component, reaching values of equipartition on the order of $10^{-3}$ in the electron time-scale, and persists longer than the proton time-scale. Particle scattering/acceleration in the self generated fields of these shear flow instabilities is also analyzed

Transverse electron-scale instability in relativistic shear flows

Electron-scale surface waves are shown to be unstable in the transverse plane of a shear flow in an initially unmagnetized plasma, unlike in the (magneto)hydrodynamics case. It is found that these unstable modes have a higher growth rate than the closely related electron-scale Kelvin-Helmholtz instability in relativistic shears. Multidimensional particle-in-cell simulations verify the analytic results and further reveal the emergence of mushroom-like electron density structures in the nonlinear phase of the instability, similar to those observed in the Rayleigh Taylor instability despite the great disparity in scales and different underlying physics. Macroscopic ($\gg c/\omega_{pe}$) fields are shown to be generated by these microscopic shear instabilities, which are relevant for particle acceleration, radiation emission and to seed MHD processes at long time-scales