Multi-Epoch HST Observations of IZw18: Characterization of Variable Stars at Ultra-Low Metallicities

Variable stars have been identified for the first time in the very metal-poor Blue Compact dwarf galaxy IZw18, using deep multi-band (F606W, F814W)time-series photometry obtained with the Advanced Camera for Surveys (ACS) on board the Hubble Space Telescope (HST). We detected 34 candidate variable stars in the galaxy. We classify three of them as Classical Cepheids, with periods of 8.71, 125.0 and 130.3 days, respectively, and other two as long period variables with periodicities longer than a hundred days. These are the lowest metallicity Classical Cepheids known so far, thus providing the opportunity to explore and fit models of stellar pulsation fo Classical Cepheids at previously inaccessible metallicities. The period distribution of the confirmed Cepheids is markedly different from what is seen in other nearby galaxies, which is likely related to the star bursting nature of IZw18. By applying to the 8.71 days Cepheid theoretical Wesenheit (V,I) relations based on new pulsation models of Classical Cepheids specifically computed for the extremely low metallicity of this galaxy (Z=0.0004, Y=0.24), we estimate the distance modulus of IZw18 to be mu_0= 31.4pm0.2 D=19.0^{+1.8}_{-1.7}Mpc) for canonical models of Classical Cepheids, and of 31.2pm0.2 mag (D=17.4^{+1.6}_{-1.6}Mpc) using over luminous models. The theoretical modeling of the star's light curves provides mu_0=31.4pm0.1 mag, D=19.0^{+0.9}_{-0.9} Mpc, in good agreement with the results from the theoretical Wesenheit relations. These pulsation distances bracket the distance of 18.2pm1.5Mpc inferred by Aloisi et al. (2007) using the galaxy's Red Giant Branch Tip.Comment: 13 Pages, 6 Figures, accepted, Ap

Crowdworker Economics in the Gig Economy

The nature of work is changing. As labor increasingly trends to casual work in the emerging gig economy, understanding the broader economic context is crucial to effective engage- ment with a contingent workforce. Crowdsourcing represents an early manifestation of this fluid, laisser-faire, on-demand workforce. This work analyzes the results of four large-scale surveys of US-based Amazon Mechanical Turk workers recorded over a six-year period, providing compa- rable measures to national statistics. Our results show that despite unemployment far higher than national levels, crowd- workers are seeing positive shifts in employment status and household income. Our most recent surveys indicate a trend away from full-time-equivalent crowdwork, coupled with a reduction in estimated poverty levels to below national figures. These trends are indicative of an increasingly flexible workforce, able to maximize their opportunities in a rapidly changing national labor market, which may have material impacts on existing models of crowdworker behavior.This work was supported by an EPSRC studentship and EPSRC grants EP/N010558/1 and EP/R004471/1

Editorial: Exploiting wheat biodiversity and agricultural practices for tackling the effects of climate change

Editorial: Exploiting wheat biodiversity and agricultural practices for tackling the effects of climate chang

The Star Formation History of NGC 1705: a Post-Starburst Galaxy on the Verge of Activity

We infer the star formation history in different regions of the blue compact dwarf NGC 1705 by comparing synthetic color-magnitude diagrams with HST optical and near-infrared photometry. We find that NGC 1705 is not a young galaxy because its star formation commenced at least 5 Gyr ago. On the other hand, we confirm the existence of a recent burst of star formation between 15 and 10 Myr ago. We also find evidence for new strong activity, which started 3 Myr ago and is still continuing. The old population is spread across the entire galaxy, while the young and intermediate stars are more concentrated in the central regions. We derive an almost continuous star formation with variable rate, and exclude the presence of long quiescent phases between the episodes during the last ~1 Gyr. The central regions experienced an episode of star formation of \~0.07 Msun/yr (for a Salpeter initial mass function [IMF]) 15 to 10 Myr ago. This coincides with the strong activity in the central super star cluster. We find a rate of ~0.3 Msun/yr for the youngest ongoing burst which started ~3 Myr ago. This is higher than in other dwarfs and comparable to the rate of NGC 1569. The star formation rate of earlier episodes is not especially high and falls in the range 10^{-3}-10^{-1} Msun/yr. The IMF is close to the Salpeter value or slightly steeper.Comment: 34 pages, including 6 tables and 14 .ps figures (9 in colour), AJ in pres

Thermogenic flux induced by lignoceric acid in peroxisomes isolated from HepG2 cells and from X- adrenoleukodystrophy and control fibroblasts

This work analyzes the thermogenic flux induced by the very long-chain fatty acid (VLCFA) lignoceric acid (C24:0) in isolated peroxisomes. Specific metabolic alterations of peroxisomes are related to a variety of disorders, the most frequent one being the neurodegenerative inherited disease X-linked adrenoleukodystrophy (X-ALD). A peroxisomal transport protein is mutated in this disorder. Due to reduced catabolism and enhanced fatty acid elongation, VLCFA accumulate in plasma and in all tissues, contributing to the clinical manifestations of this disorder. During peroxisomal metabolism, heat is produced but it is considered lost. Instead, it is a form of energy that could play a role in molecular mechanisms of this pathology and other neurodegenerative disorders. The thermogenic flux induced by lignoceric acid (C24:0) was estimated by isothermal titration calorimetry in peroxisomes isolated from HepG2 cells and from fibroblasts obtained from X-linked adrenoleukodystrophy patients and healthy subjects. Heat flux induced by lignoceric acid in HepG2 peroxisomes was exothermic, indicating normal peroxisomal metabolism. In X-ALD peroxisomes the heat flux was endothermic, indicating the requirement of heat/energy, possibly for cellular metabolism. In fibroblasts from healthy subjects the effect was less pronounced than in HepG2, a kind of cell known to have greater FA metabolism than fibroblasts. Our hypothesis is that heat is not lost but it could act a s an activator, for example on the heat-sensitive pathway related to TRVP2 receptors. To investigate this hypothesis we focused on peroxisomal metabolism, considering that impaired heat generation could contribute to the development of peroxisomal neurodegenerative disorders

The Acute Inflammatory Response in Trauma / Hemorrhage and Traumatic Brain Injury: Current State and Emerging Prospects

Traumatic injury/hemorrhagic shock (T/HS) elicits an acute inflammatory response that may result in death. Inflammation describes a coordinated series of molecular, cellular, tissue, organ, and systemic responses that drive the pathology of various diseases including T/HS and traumatic brain injury (TBI). Inflammation is a finely tuned, dynamic, highly-regulated process that is not inherently detrimental, but rather required for immune surveillance, optimal post-injury tissue repair, and regeneration. The inflammatory response is driven by cytokines and chemokines and is partially propagated by damaged tissue-derived products (Damage-associated Molecular Patterns; DAMP's). DAMPs perpetuate inflammation through the release of pro-inflammatory cytokines, but may also inhibit anti-inflammatory cytokines. Various animal models of T/HS in mice, rats, pigs, dogs, and non-human primates have been utilized in an attempt to move from bench to bedside. Novel approaches, including those from the field of systems biology, may yield therapeutic breakthroughs in T/HS and TBI in the near future

I Zw 18 revisited with HST/ACS and Cepheids: New Distance and Age

We present new V and I-band HST/ACS photometry of I Zw 18, the most metal-poor blue compact dwarf (BCD) galaxy in the nearby universe. It has been argued in the past that I Zw 18 is a very young system that started forming stars only 1 Gyr) red giant branch (RGB) stars may also exist. Our new data, once combined with archival HST/ACS data, provide a deep and uncontaminated optical color-magnitude diagram (CMD) that now strongly indicates an RGB. The RGB tip (TRGB) magnitude yields a distance modulus (m-M)_0 = 31.30 +/- 0.17, i.e., D = 18.2 +/- 1.5 Mpc. The time-series nature of our observations allows us to also detect and characterize for the first time three classical Cepheids in I~Zw~18. The time-averaged Cepheid and magnitudes are compared to the VI reddening-free Wesenheit relation predicted from new non-linear pulsation models specifically calculated at the metallicity of I Zw 18. For the one bona-fide classical Cepheid with a period of 8.63 days this implies a distance modulus (m-M)_0 = 31.42 +/- 0.26. The other two Cepheids have unusually long periods (125.0 and 129.8 d) but are consistent with this distance. The coherent picture that emerges is that I Zw 18 is older and farther away than previously believed. This rules out the possibility that I Zw 18 is a truly primordial galaxy formed recently (z < 0.1) in the local universe.Comment: 12 pages, 3 figures, submitted to ApJ

Feedback in the local LBG Analog Haro 11 as probed by far-UV and X-ray observations

We have re-analyzed FUSE data and obtained new Chandra observations of Haro 11, a local (D_L=88 Mpc) UV luminous galaxy. Haro 11 has a similar far-UV luminosity (10^10.3 L_\odot), UV surface brightness (10^9.4 L_\odot kpc^-2), SFR, and metallicity to that observed in Lyman Break Galaxies (LBGs). We show that Haro 11 has extended, soft thermal (kT~0.68 keV) X-ray emission with a luminosity and size which scales with the physical properties (e.g. SFR, stellar mass) of the host galaxy. An enhanced alpha/Fe, ratio of ~4 relative to solar abundance suggests significant supernovae enrichment. These results are consistent with the X-ray emission being produced in a shock between a supernovae driven outflow and the ambient material. The FUV spectra show strong absorption lines similar to those observed in LBG spectra. A blueshifted absorption component is identified as a wind outflowing at ~200-280 km/s. OVI\lambda\lambda1032,1038 emission, the dominant cooling mechanism for coronal gas at T~10^5.5 K is also observed. If associated with the outflow, the luminosity of the OVI emission suggests that <20% of the total mechanical energy from the supernovae and solar winds is being radiated away. This implies that radiative cooling through OVI is not significantly inhibiting the growth of the outflowing gas. In contradiction to the findings of Bergvall et al 2006, we find no convincing evidence of Lyman continuum leakage in Haro 11. We conclude that the wind has not created a `tunnel' allowing the escape of a significant fraction of Lyman continuum photons and place a limit on the escape fraction of f_{esc}<2%. Overall, both Haro 11 and a previously observed LBG analogue VV 114, provide an invaluable insight into the X-ray and FUV properties of high redshift LBGs.Comment: Accepted for publication in ApJ, 40 pages, 17 figure