Endocrine, Physiological and Histopathological Responses of Fish and their Larvae to Stress with Emphasis on Exposure to Crude Oil and Various Petroleum Hydrocarbons

Various endocrine and physiological responses of fish exposed to forceful physical and chemical stimuli are reviewed with emphasis on the effects of crude oils and their hydrocarbon constituents. The chemistry and toxicity of petroleum hydrocarbons are examined and methods for experimental exposure of fish to crude oil and petroleum hydrocarbons are considered. A variety of blood-borne parameters recognized as reliable tools in determining the relative severity of stress in fish are reviewed. The effects of stress and petroleum hydrocarbons on endocrine responses including changes in plasma catecholamines, corticosteroids, and thyroid hormones are reviewed. The physiological responses: changes in plasma glucose, osmotic and ionic regulation, blood oxygen, hematocrit and hemoglobin concentration are explored, and histopathological effects of crude oil on fish are reviewed. Recent studies of the effects of petroleum hydrocarbons on fish larvae are considered and the increased sensitivity of the early life stages of fish are highlighted

M-Learning: The New Horizon of Learning at SQU

M-learning extends the theory and practice of learning and mobility in converging technological environments. Developing a smart course in order to improve the standard of education at Sultan Qaboos University (SQU) is one of the main aims of the current authors. This proposal requires developing innovative applications for ubiquitous, mobile technologies for learning. This kind of development covers new educational and technological methods and concepts for supporting formal and informal learning. SQU is currently using Moodle as the open source e-learning management system to support and enhance traditional learning. Although elearning in SQU has proven its importance in enhancing traditional learning, it is limited to areas and locations where a personal computer exists. This constraint is a burden to many e-learning users who are staff or students, especially if they live in rural areas of Oman. To overcome this drawback, an investigative survey of the importance of m-learning was designed and distributed to SQU students. The results showed that almost all students favored and supported the idea and requested the implementation of a m-learning application. As a step forward, this paper proposes an extension for e-learning—a new m-learning tool to support learners who use mobile device technologies. Our goal in introducing m-learning at SQU is not to replace e-learning but to complement and improve it so both modalities are available, since each grants certain advantages to users

Homozygous loss-of-function variants in FILIP1 cause autosomal recessive arthrogryposis multiplex congenita with microcephaly

Arthrogryposis multiplex congenita forms a broad group of clinically and etiologically heterogeneous disorders characterized by congenital joint contractures that involve at least two different parts of the body. Neurological and muscular disorders are commonly underlying arthrogryposis. Here, we report five affected individuals from three independent families sharing an overlapping phenotype with congenital contractures affecting shoulder, elbow, hand, hip, knee and foot as well as scoliosis, reduced palmar and plantar skin folds, microcephaly and facial dysmorphism. Using exome sequencing, we identified homozygous truncating variants in FILIP1 in all patients. FILIP1 is a regulator of filamin homeostasis required for the initiation of cortical cell migration in the developing neocortex and essential for the differentiation process of cross-striated muscle cells during myogenesis. In summary, our data indicate that bi-allelic truncating variants in FILIP1 are causative of a novel autosomal recessive disorder and expand the spectrum of genetic factors causative of arthrogryposis multiplex congenita

Para que servem os inventários de fauna?

Inventários de fauna acessam diretamente a diversidade de uma localidade, em um determinado espaço e tempo. Os dados primários gerados pelos inventários compõem uma das ferramentas mais importantes na tomada de decisões a respeito do manejo de áreas naturais. Entretanto, vários problemas têm sido observados em diversos níveis relacionados aos inventários de fauna no Brasil e vão desde a formação de recursos humanos até a ausência de padronização, de desenho experimental e de seleção de métodos inadequados. São apresentados estudos de caso com mamíferos, répteis, anfíbios e peixes, nos quais são discutidos problemas como variabilidade temporal e métodos para detecção de fauna terrestre, sugerindo que tanto os inventários quanto os programas de monitoramento devam se estender por prazos maiores e que os inventários devem incluir diferentes metodologias para que os seus objetivos sejam plenamente alcançados.Inventories of fauna directly access the diversity of a locality in a certain period of time. The primary data generated by these inventories comprise one of the most important steps in decisions making regarding the management of natural areas. However, several problems have been observed at different levels related to inventories of fauna in Brazil, and range from the training of humans to the lack of standardization of experimental design and selection of inappropriate methods. We present case studies of mammals, reptiles, amphibians and fishes, where they discussed issues such temporal variability and methods for detection of terrestrial fauna, suggesting that both inventories and monitoring programs should be extended for longer terms and that inventories should include different methodologies to ensure that their goals are fully achieved

Conservation status of marine biodiversity of the Western Indian Ocean

The Western Indian Ocean is comprised of productive and highly diverse marine ecosystems that are rich sources of food security, livelihoods, and natural wonder. The ecological services that species provide are vital to the productivity of these ecosystems and healthy biodiversity is essential for the continued support of economies and local users. The stability of these valuable resources, however, is being eroded by growing threats to marine life from overexploitation, habitat degradation and climate change, all of which are causing serious reductions in marine ecosystem services and the ability of these ecosystems to support human communities. Quantifying the impacts of these threats and understanding the conservation status of the region’s marine biodiversity is a critical step in applying informed management and conservation measures to mitigate loss and retain the ecological value of these systems. This report highlights trends in research needs for species in the region, including priorities for fundamental biological and ecological research and quantifying trends in the populations of species. The assessments and analyses submitted in this report should inform conservation decision-making processes and will be valuable to policymakers, natural resource managers, environmental planners and NGOs

The Removal of Ibuprofen Drugs Residues from Municipal Wastewater by Moringa Oleifera Seeds

Municipal wastewater may contain residues of different drugs causing severe chemical contamination of water bodies. However, the microbial degradation of Wastewater Treatment Plants (WWTP) may not eliminate such drug residues completely. The current work was designed to remove the Ibuprofen drug residues by using the Moringa Oleifera seeds. Various testing methods such as Brunauer, Emmett and Teller (BET), Transmission Electron Microscopy (TEM), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR) were applied to assess the efficiency of such plant seeds in bioremoval of ibuprofen residues from municipal wastewater The batch reactor was used to find the optimum operating conditions using various parameters with different pH values, duration time, Ibuprofen concentration and various quantities of plant seeds. In the batch reactor, the operation conditions were: pH 7, duration time 150 min, Ibuprofen dose of 1000 mg/l, activated adsorbents and Moringa Oleifera seeds in the amount of 1000 mg/l. Moreover, the packed bed reactor was used to examine different parameters such as initial Ibuprofen concentration, flow rate and bed depth for 6 hours. It was found that the best conditions were 2 cm depth, and 25 l/hr flow rate. Meanwhile, the kinetic constants were studied by adsorption equilibrium with the isothermal Langmuir and Freundlich models. The best results were shown with the Freundlich isotherm, and the first pseudo order was more suitable for the removal of Ibuprofen by adsorbed activation of Moringa Oleifera seeds

Endocrine, Physiological and Histopathological Responses of Fish and their Larvae to Stress with Emphasis on Exposure to Crude Oil and Various Petroleum Hydrocarbons

Various endocrine and physiological responses of fish exposed to forceful physical and chemical stimuli are reviewed with emphasis on the effects of crude oils and their hydrocarbon constituents. The chemistry and toxicity of petroleum hydrocarbons are examined and methods for experimental exposure of fish to crude oil and petroleum hydrocarbons are considered. A variety of blood-borne parameters recognized as reliable tools in determining the relative severity of stress in fish are reviewed. The effects of stress and petroleum hydrocarbons on endocrine responses including changes in plasma catecholamines, corticosteroids, and thyroid hormones are reviewed. The physiological responses: changes in plasma glucose, osmotic and ionic regulation, blood oxygen, hematocrit and hemoglobin concentration are explored, and histopathological effects of crude oil on fish are reviewed. Recent studies of the effects of petroleum hydrocarbons on fish larvae are considered and the increased sensitivity of the early life stages of fish are highlighted

M-Learning: The New Horizon of Learning at SQU

M-learning extends the theory and practice of learning and mobility in converging technological environments. Developing a smart course in order to improve the standard of education at Sultan Qaboos University (SQU) is one of the main aims of the current authors. This proposal requires developing innovative applications for ubiquitous, mobile technologies for learning. This kind of development covers new educational and technological methods and concepts for supporting formal and informal learning. SQU is currently using Moodle as the open source e-learning management system to support and enhance traditional learning. Although elearning in SQU has proven its importance in enhancing traditional learning, it is limited to areas and locations where a personal computer exists. This constraint is a burden to many e-learning users who are staff or students, especially if they live in rural areas of Oman. To overcome this drawback, an investigative survey of the importance of m-learning was designed and distributed to SQU students. The results showed that almost all students favored and supported the idea and requested the implementation of a m-learning application. As a step forward, this paper proposes an extension for e-learning—a new m-learning tool to support learners who use mobile device technologies. Our goal in introducing m-learning at SQU is not to replace e-learning but to complement and improve it so both modalities are available, since each grants certain advantages to users