1,346 research outputs found
The Efficacy and Clinical Safety of Various Analgesic Combinations for Post-Operative Pain after Third Molar Surgery: A Systematic Review and Meta-Analysis.
Objectives
To run a systematic review and meta-analysis of randomized clinical trials aiming to answer the clinical question "which analgesic combination and dosage is potentially the most effective and safe for acute post-operative pain control after third molar surgery?".
Materials and Methods
A systematic search of computer databases and journals was performed. The search and the evaluations of articles were performed by 2 independent reviewers in 3 rounds. Randomized clinical trials related to analgesic combinations for acute post-operative pain control after lower third molar surgery that matched the selection criteria were evaluated to enter in the final review.
Results
Fourteen studies with 3521 subjects, with 10 groups (17 dosages) of analgesic combinations were included in the final review. The analgesic efficacy were presented by the objective pain measurements including sum of pain intensity at 6 hours (SPID6) and total pain relief at 6 hours (TOTPAR6). The SPID6 scores and TOTPAR6 scores of the reported analgesic combinations were ranged from 1.46 to 6.44 and 3.24 - 10.3, respectively. Ibuprofen 400mg with oxycodone HCL 5mg had superior efficacy (SPID6: 6.44, TOTPAR6: 9.31). Nausea was the most common adverse effect, with prevalence ranging from 0-55%. Ibuprofen 200mg with caffeine 100mg or 200mg had a reasonable analgesic effect with fewer side effects.
Conclusion
This systematic review and meta-analysis may help clinicians in their choices of prescribing an analgesic combination for acute post-operative pain control after lower third molar surgery. It was found in this systematic review Ibuprofen 400mg combined with oxycodone HCL 5mg has superior analgesic efficacy when compared to the other analgesic combinations included in this study.published_or_final_versio
Interaction avec un picoprojecteur : État de l'art et analyse des attentes des utilisateurs
4 pagesNational audienceUn picoprojecteur est un vidéoprojecteur portatif aux dimensions réduites. On appelle également picophone, un smartphone qui intègre un tel dispositif. Encore très peu diffusé, ce nouveau dispositif interactif mobile est commercialisé depuis 2 ans. Cet article dresse un état de l'art des recherches actuellement menées sur le sujet, puis présente les attentes d'un panel de 50 utilisateurs potentiels
Oral tolerance and functional Treg cells are induced in BALB/c mice after gavage with bovine β-lactoglobulin (BLG)
Sensitization to a purified cow’s milk (CM) allergen facilitates further oral sensitization to other CM proteins in mice
Alternatives to colonoscopy for population-wide colorectal cancer screening
published_or_final_versio
Comparing generalized and specific problematic smartphone/internet use: longitudinal relationships between smartphone application- based addiction and social media addiction and psychological distress
Background and aims: The literature has proposed two types of problematic smartphone/internet use: generalized problematic use and specific problematic use. However, longitudinal findings on the associations between the two types of problematic use and psychological distress are lacking among East-Asians. The present study examined temporal associations between both generalized and specific problematic use of the smartphone/internet, and psychological distress.
Methods: Hong Kong University students (N 5 308; 100 males; mean age 5 23.75 years; SD ± 5.15) were recruited with follow-ups at three, six, and nine months after baseline assessment. All participants completed the Smartphone Application-Based Addiction Scale (for generalized problematic smartphone/internet use), the Bergen Social Media Addiction Scale (for specific problematic smartphone/internet use), and the Hospital Anxiety and Depression Scale (for psychological distress) in each assessment. Latent growth modeling (LGM) was constructed to understand temporal associations between generalized/specific problematic use and psychological distress.
Results: The LGM suggested that the intercept of generalized problematic use was significantly associated with the intercept of psychological distress (standardized coefficient [b] 5 0.32; P < 0.01). The growth of generalized problematic use was significantly associated with the growth of psychological distress (b 5 0.51; P < 0.01). Moreover, the intercept of specific problematic use was significantly associated with the intercept of psychological distress (b 5 0.28; P < 0.01) and the growth of psychological distress (b 5 0.37; P < 0.01).
Conclusion: The initial level of problematic use of the smartphone/internet may prevent psychological distress
Comparison of the immune response induced in mice experimentally sensitized with genetically modified MON810 maize vs its conventional counterpart
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Psychometric testing of three Chinese online-related addictive behavior instruments among Hong Kong university students
Objective: To validate the Chinese version of the nine-item Internet Gaming Disorder Scales- Short Form (IGDS-SF9), Bergen Social Media Addiction Scale (BSMAS), and Smartphone Application-Based Addiction Scale (SABAS) among Hong Kong university students.
Participants and Methods: Participants aged between 17 and 30 years participated in the present study (n=307; 32.4% males; mean [SD] age=21.64 [8.11]). All the participants completed the IGDS-SF9, BSMAS, SABAS, and the Hospital Anxiety and Depression Scale (HADS). Confirmatory factor analyses (CFAs) were used to examine the factorial structures and the unidimensionality for IGDS-SF9, BSMAS, and SABAS.
Results: CFAs demonstrated that the three scales were all unidimensional with satisfactory fit indices: comparative fit index = 0.969 to 0.992. In addition, the IGDS-SF9 and BSMAS were slightly modified based on the modification index in CFA.
Conclusions: The Chinese IGDS-SF9, BSMAS, and SABAS are valid instruments to assess the addiction levels of internet-related activities for Hong Kong university students
Specific IgE responses in patients allergic to goat’s milk but tolerant to cow’s milk: involvement of minor differences in primary structure between caprine and bovine caseins
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