An efficient coupled-mode/FEM numerical method for linear wave propagation over 3D variable bathymetry domains

© Copyright 2016 by the International Society of Offshore and Polar Engineers (ISOPE).A robust numerical algorithm for the simulation of linear water wave propagation over uneven bottom topography is developed. The solution strategy is based on a highly efficient reduction of the 3D problem to a system of partial differential equations by means of a consistent coupled mode series expansion for water wave propagation over variable seabed. The main feature of the proposed series representation is the incorporation of special terms in the vertical expansion basis, accounting for the bottom boundary condition of the varying seabed. The formulation of the 2D system follows from the variations, with respect to the expansion coefficients (functions of the horizontal plane spatial coordinates), of a suitably chosen energy functional. The resulting model is a variable coefficient system of second order, with respect to the spatial coordinates, Partial Differential Equations (PDEs). Linear triangular finite elements are employed for the solution of this PDE system offering flexibility in the discretization of complex 2D domains. The numerical method developed has been applied to several test cases yielding accurate representations of the wave field at relatively low computational cost and small execution times

Time-domain, shallow-water hydroelastic analysis of VLFS elastically connected to the seabed

In order to ensure the safe operation of a VLFS, a combination of mooring, breakwater and other motion reducing systems is employed. In the present work, the transient hydroelastic response of a floating, thin elastic plate, elastically connected to the seabed, is examined. The plate is modelled as an Euler-Bernoulli strip, while the linearized shallow water equations are used for the hydrodynamic modelling. Elastic connectors are approximated by a series of simple spring-dashpot systems positioned along the strip. A higher order finite element scheme is employed for the calculation of the hydroelastic response of the strip-connector configuration, over the shallow bathymetry. After the definition of the initial-boundary value problem, its variational form is derived and discussed. Next, on the basis of the aforementioned formulation, an energy balance expression is obtained. The effect of variable bathymetry on the response of a two connector-strip system, is examined by means of three seabed profiles, featuring a flat bottom, an upslope and a downslope environment. For the flat bottom case, the strip response mitigating effect exerted by the employment of two and three elastic connectors is considered. Finally, by means of the derived energy balance equation, the energy exchange is monitored, providing a valuable insight into the transient phenomena that take place in the studied configurations.The present work has been supported by the project HYDELFS funded by the Operational Program "Education and Lifelong Learning" of the National Strategic Reference Framework (NSRF 2007-2013) -Research Funding Program ARHIMEDES-III: Investing in knowledge society through the European Social Fund. In particular, author Theodosios K. Papathanasiou acknowledges support from the aforementioned program for the period from 6/9/2012 to 30/09/2014

J-shaped relationship between habitual coffee consumption and 10-year (2002–2012) cardiovascular disease incidence:the ATTICA study

Purpose: The purpose of this work was to evaluate the association between coffee consumption and 10-year cardiovascular disease (CVD) incidence in the ATTICA study, and whether this is modified by the presence or absence of metabolic syndrome (MetS) at baseline. Methods: During 2001–2002, 3042 healthy adults (1514 men and 1528 women) living in the greater area of Athens were voluntarily recruited to the ATTICA study. In 2011–2012, the 10-year follow-up was performed in 2583 participants (15% of the participants were lost to follow-up). Coffee consumption was assessed by a validated food-frequency questionnaire at baseline (abstention, low, moderate, heavy). Incidence of fatal or non-fatal CVD event was recorded using WHO-ICD-10 criteria and MetS was defined by the National Cholesterol Education Program Adult Treatment panel III (revised) criteria. Results: Overall, after controlling for potential CVD risk factors, the multivariate analysis revealed a J-shaped association between daily coffee drinking and the risk for a first CVD event in a 10-year period. Particularly, the odds ratio for low (250 ml/day), compared to abstention, were 0.44 (95% CI 0.29–0.68), 0.49 (95% CI 0.27–0.92) and 2.48 (95% CI 1.56–1.93), respectively. This inverse association was also verified among participants without MetS at baseline, but not among participants with the MetS. Conclusions: These data support the protective effect of drinking moderate quantities of coffee (equivalent to approximately 1–2 cups daily) against CVD incidents. This protective effect was only significant for participants without MetS at baseline

Quality of Reporting and Study Design of CKD Cohort Studies Assessing Mortality in the Elderly Before and After STROBE:A Systematic Review

BACKGROUND:The STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) statement was published in October 2007 to improve quality of reporting of observational studies. The aim of this review was to assess the impact of the STROBE statement on observational study reporting and study design quality in the nephrology literature. STUDY DESIGN:Systematic literature review. SETTING & POPULATION:European and North American, Pre-dialysis Chronic Kidney Disease (CKD) cohort studies. SELECTION CRITERIA FOR STUDIES:Studies assessing the association between CKD and mortality in the elderly (>65 years) published from 1st January 2002 to 31st December 2013 were included, following systematic searching of MEDLINE & EMBASE. PREDICTOR:Time period before and after the publication of the STROBE statement. OUTCOME:Quality of study reporting using the STROBE statement and quality of study design using the Newcastle Ottawa Scale (NOS), Scottish Intercollegiate Guidelines Network (SIGN) and Critical Appraisal Skills Programme (CASP) tools. RESULTS:37 papers (11 Pre & 26 Post STROBE) were identified from 3621 potential articles. Only four of the 22 STROBE items and their sub-criteria (objectives reporting, choice of quantitative groups and description of and carrying out sensitivity analysis) showed improvements, with the majority of items showing little change between the period before and after publication of the STROBE statement. Pre- and post-period analysis revealed a Manuscript STROBE score increase (median score 77.8% (Inter-quartile range [IQR], 64.7-82.0) vs 83% (IQR, 78.4-84.9, p = 0.05). There was no change in quality of study design with identical median scores in the two periods for NOS (Manuscript NOS score 88.9), SIGN (Manuscript SIGN score 83.3) and CASP (Manuscript CASP score 91.7) tools. LIMITATIONS:Only 37 Studies from Europe and North America were included from one medical specialty. Assessment of study design largely reliant on good reporting. CONCLUSIONS:This study highlights continuing deficiencies in the reporting of STROBE items and their sub-criteria in cohort studies in nephrology. There was weak evidence of improvement in the overall reporting quality, with no improvement in methodological quality of CKD cohort studies between the period before and after publication of the STROBE statement