1,507 research outputs found
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Thermal and wind devices for multisensory human-computer interaction: an overview
In order to create immersive experiences in virtual worlds, we need to explore different human senses (sight, hearing, smell, taste, and touch). Many different devices have been developed by both industry and academia towards this aim. In this paper, we focus our attention on the researched area of thermal and wind devices to deliver the sensations of heat and cold against peopleâs skin and their application to human-computer interaction (HCI). First, we present a review of devices and their features that were identified as relevant. Then, we highlight the usersâ experience with thermal and wind devices, highlighting limitations either found or inferred by the authors and studies selected for this survey. Accordingly, from the current literature, we can infer that, in wind and temperature-based haptic systems (i) users experience wind effects produced by fans that move air molecules at room temperature, and (ii) there is no integration of thermal components to devices intended for the production of both cold or hot airflows. Subsequently, an analysis of why thermal wind devices have not been devised yet is undertaken, highlighting the challenges of creating such devices.EspĂrito Santo Research and Innovation Foundation (FAPES, Brazil) - Finance Code 2021-GL60J), the Coordination for the Improvement of Higher Education Personnel (CAPES, Brazil) - Finance Code 88881.187844/2018-01 and 88887.570688/2020-00 and by the National Council for Scientific and Technological (CNPq, Brazil) - Finance Code 307718/2020-4. The work was also funded by the European Unionâs Horizon 2020 Research and Innovation programme under Grant Agreement no. 688503. E. B. Saleme additionally acknowledges aid from the Federal Institute of EspĂrito Santo
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Technology Enhanced Mulsemedia Learning (TEML) for Learners with Dyslexia
Mulsemedia-multiple sensorial media- includes both traditional multimedia and human sensorial effects, which gives immersive real-world experience. The booming of new technology and wearable devices creates a new avenue for Mulsemedia research in education and has brought new opportunities for Technology Enhanced Mulsemedia Learning (TEML). Traditional methods focus on unisensory experiences, even though the surrounding environment is multisensory. Moreover, this type of learning helps to stimulate various sensory channels to reinforce the learning process, which can also more benefit individuals with a variety of learning disabilities particularly dyslexia which affects a person's ability to read. Moreover, TEML helps to obtain 21st-century learning skills such as cognitive, productivity, social-cultural, metacognitive, and technological dimensions. This paper proposes TEML for learners with dyslexia, for that, this study focuses on an approach for identifying methods for dyslexia, a method for designing Mulsemedia devices using IoT technology, and an evaluation method for performing quality of experience (QoS) using questionnaire, and physiological signals such as GSR (Galvanic Skin Responses), and EEG (Electroencephalography). Those methods help to analyze the learner's emotional responses while experiencing Mulsemedia content.This work is supported by the Centre for Machine Learning and Intelligence (CMLI) funded by the Department of Science and Technology (DST-CURIE)
The C-terminal region of Trypanosoma cruzi MASPs is antigenic and secreted via exovesicles.
Trypanosoma cruzi is the etiological agent of Chagas disease, a neglected and emerging tropical disease, endemic to South America and present in non-endemic regions due to human migration. The MASP multigene family is specific to T. cruzi, accounting for 6% of the parasite's genome and plays a key role in immune evasion. A common feature of MASPs is the presence of two conserved regions: an N-terminal region codifying for signal peptide and a C-terminal (C-term) region, which potentially acts as GPI-addition signal peptide. Our aim was the analysis of the presence of an immune response against the MASP C-term region. We found that this region is highly conserved, released via exovesicles (EVs) and has an associated immune response as revealed by epitope affinity mapping, IFA and inhibition of the complement lysis assays. We also demonstrate the presence of a fast IgM response in Balb/c mice infected with T. cruzi. Our results reveal the presence of non-canonical secreted peptides in EVs, which can subsequently be exposed to the immune system with a potential role in evading immune system targets in the parasite
Determinants of out-of-pocket health expenditure on children: an analysis of the 2004 Pelotas Birth Cohort
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