Investigation of growth conditions, crystal structure and surface morphology of SmS films fabricated by MOCVD technique

The polycrystalline SmS films were fabricated by MOCVD technique using a number of ditiocarbamates, synthesized by different techniques. The growth kinetics and temperature dependencies of the film growth rate are investigated, which allowed us to determine the activation energies and the reaction type. The investigations of the structure and surface morphology of films were carried out. The technological conditions are determined providing the fabrication of single-phase SmS films of cubic modification with the most ordered crystal structure

Изучение видового разнообразия бактерий рода Bifidobacterium кишечной микрофлоры с использованием метода MALDI-TOF масс-спектрометрии

Background: The members of genus Bifidobacterium represent a significant part of intestinal microbiota in adults and predominate in infants. Species repertoire of the intestinal bifidobacteria is known to be subjected to major changes with age; however, many details of this process are still to be elucidated.Objective: Our aim was to study the diversity of intestinal bifidobacteria and changes of their qualitative and quantitative composition characteristics during the process of growing up using MALDI-TOF mass-spectrometric analysis of pure bacterial cultures.Methods: A cross-sectional study of bifidobacteria in the intestinal microbiota was performed in 93 healthy people of the ages from 1 month to 57 years. Strains were identified using Microflex LT MALDI-TOF MS, the confirmation was performed by 16S rRNA gene fragment sequencing.Results: 93% of isolated bifidobacterial strains were successfully identified using MALDI-TOF mass-spectrometry. At least two of the strains from each species were additionally identified by 16S rRNA gene fragment sequencing, in all of the cases the results were the same. It was shown that the total concentration of bifidobacteria decreases with age (p 0.001) as well as the frequency of isolation of Bifidobacterium bifidum (p =0.020) and Bifidobacterium breve (p 0.001), and the frequency of isolation of Bifidobacterium adolescentis, increases (p 0.001), representing the continuous process of transformation of microbiota.Conclusion: The method of MALDI-TOF mass spectrometry demonstrated the ability to perform rapid and reliable identification of bifidobacteria that allowed the study of changes in the quantitative and qualitative characteristics of human microbiota in the process of growing up.Представители рода Bifidobacterium представляют значительную часть микрофлоры кишечника взрослых людей и численно доминируют в микрофлоре младенцев. Известно, что видовой состав кишечных бифидобактерий подвергается сильным изменениям с возрастом, однако многие детали этого процесса остаются неясными.Цель исследования: изучить видовое разнообразие бифидобактерий кишечника и изменения их качественного и количественного состава в процессе взросления человека при помощи технологии MALDI-TOF масс-спектрометрического анализа белковых профилей чистых культур.Методы: кросс-секционное исследование разнообразия бифидобактерий в составе нормальной микрофлоры кишечника проведено у 93 человек в возрасте от 1 мес до 57 лет. Осуществляли выделе- ние чистых культур и их идентификацию на приборе Microflex LT MALDI-TOF MS (Bruker Daltonics, Германия), подтверждение реализовывали с использованием секвенирования фрагмента гена 16S рРНК.Результаты: с применением MALDI-TOF масс-спектрометрии было успешно идентифицировано 93% выделенных штаммов бифидобактерий. Минимум по 2 представителя от каждого из видов были дополнительно определены методом секвенирования фрагмента гена 16SрРНК; во всех случаях результаты методов совпали. Показано, что с возрастом происходит снижение общей концентрации бифидобактерий (p 0,001), уменьшается встречаемость видов Bifidobacterium bifidum (p =0,020) и Bifidobacterium breve (p 0,001), а встречаемость вида Bifidobacterium adolescentis увеличивается (p 0,001), отражая постепенные процессы перестройки микрофлоры.Заключение: метод MALDI-TOF масс-спектрометрии показал возможность быстрой и надежной идентификации бифидобактерий, позволившей провести исследование изменений количественных и качественных показателей микрофлоры человека в процессе взрослени

Sign reversal of the Hall resistance in the mixed-state of La1.89_{1.89} Ce0.11_{0.11}CuO4_{4} and La1.89_{1.89}Ce0.11_{0.11}(Cu0.99_{0.99}Co0.01_{0.01})O4_{4} thin films

The transport properties of La$_{1.89}$Ce$_{0.11}$CuO$_{4}$(LCCO) and La$_{1.89}$Ce$_{0.11}$(Cu$_{0.99}$Co$_{0.01}$)O$_{4}$ (LCCO:Co) superconducting thin films are investigated. When the external field $\bf H$ is applied along the crystallographic c-axis, a double sign reversal of the Hall voltage in the mixed state of LCCO:Co thin films is observed whereas a single sign reversal is detected in LCCO. A double sign reversal of the Hall signal in LCCO can be recovered if the magnetic field is tilted away from the plane of the film. We find that the transition from one to two of the Hall sign reversal coincides with the change in the pinning from strong to weak. This temperature/field induced transition is caused either by the magnetic impurities in LCCO:Co or by the coupling between the pancake vortices and the in-plane Josephson vortices in LCCO. These results are in agreement with early theoretical and numerical predictions.Comment: 6 pages, 4 figures, the proceedings of VORTEX VII in Physica

EFFECTIVIZATION OF THE TRANSPORT TELECOMMUNICATIONS DESIGN FOR CORPORATIVE SYSTEM OF AN INDUSTRIAL OBJECT

Improvement of transport network design efficiency problems at the expense of the  system approach to the estimation of network quality and assigned communications services quality are considered. Methods and technical facilities that provide constancy and control complexness of network quality on different stages of its life cycle are offered

Arterial ischemic stroke in children: The use of thrombolytic therapy

In recent years, the number of diagnosed cases of arterial ischemic stroke (AIS) in children has increased significantly. Intravenous and endovascular thrombolytic therapy of AIS is the most effective treatment for adults. Currently, the literature provides descriptions of a series of clinical observations in children with AIS, that received therapy with thrombolysis. This type of therapy is recommended to be performed on the basis of pediatric stroke primary centers. Since 2018, on the basis of the Center for Cerebrovascular Pathology Treatment, Morozov Children’s City Clinical Hospital, 34 children with AIS aged 3,5-14 years received intravenous thrombolytic therapy. The article describes the clinical observations of 4 patients with AIS who underwent treatment with thrombolysis. © 2020, Pediatria Ltd. All rights reserved

Problems and controversial issues in diagnostics of pneumonia in newborns

The literature review on the basis of modern domestic and foreign literature data presents information about pneumonia in newborns. It discusses issues of classification and diagnostic criteria for the disease; summarizes actual information about peculiarities, epidemiology of neonatal pneumonia, etiology and specific risk factors for congenital pneumonia, pneumonia with early and late onset, including nosocomial and ventilator-associated pneumonia, communityacquired pneumonia in newborns. It provides data on frequency of respiratory and general clinical symptoms, results of image diagnostics and laboratory diagnostics of the disease. © 2019, Pediatria Ltd.. All rights reserved

Determining the components and the structure of the decision support system software for automatic control systems of the complex systems

Пропонується мінімально необхідний склад і структура комплексу програм СППР для автоматизованих систем управління складними системами, які функціонують в умовах динамічної обстановки і невизначеності інформації.Предлагается минимально необходимый состав и структура комплекса программ СППР для автоматизированных систем управления сложными системами, которые функционируют в условиях динамической обстановки и неопределенности информации.The article considers the minimum required components and structure of the decision support systems software for automatic control systems of the complex systems operating in dynamic situation and with ambiguous information