18 research outputs found

    SOME INSTRUMENTAL AND ETHICAL PROBLEMS OF SOCIOLOGICAL EDUCATION IN MODERN RUSSIA: ETHNOGRAPHY ATTEMPT

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    Статья посвящена анализу ряду инструментальных и этических проблем подготовки социологов. В качестве инструментальных анализируются проблема реализации так называемой «исследовательской педагогики», ее преимущества перед «транслирующей педагогикой»; проблема «стерильности» социологического образования, его оторванности от реальных социальных проблем; проблема неопределенности целей социологической магистратуры. Наряду с этим анализируется и этическая проблема профессии, выражающаяся в сервильноcти к заказчика (власти преимущественно). The article is devoted to analysis of some instrumental and ethic problems of the sociologist training. The problem of realization so called «the research pedagogic», its preferences upon «the reproducing pedagogic», the problem of the social education «sterility», separation from the real social problems, the problem of uncertain aims of the sociological magistratura as instrumental problems are analyzed. At the same time ethic problem of profession, displaying in service of customer (power) is analyzed

    Virtual Ontogeny of Cortical Growth Preceding Mental Illness

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    Background: Morphology of the human cerebral cortex differs across psychiatric disorders, with neurobiology and developmental origins mostly undetermined. Deviations in the tangential growth of the cerebral cortex during pre/perinatal periods may be reflected in individual variations in cortical surface area later in life. Methods: Interregional profiles of group differences in surface area between cases and controls were generated using T1-weighted magnetic resonance imaging from 27,359 individuals including those with attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depressive disorder, schizophrenia, and high general psychopathology (through the Child Behavior Checklist). Similarity of interregional profiles of group differences in surface area and prenatal cell-specific gene expression was assessed. Results: Across the 11 cortical regions, group differences in cortical area for attention-deficit/hyperactivity disorder, schizophrenia, and Child Behavior Checklist were dominant in multimodal association cortices. The same interregional profiles were also associated with interregional profiles of (prenatal) gene expression specific to proliferative cells, namely radial glia and intermediate progenitor cells (greater expression, larger difference), as well as differentiated cells, namely excitatory neurons and endothelial and mural cells (greater expression, smaller difference). Finally, these cell types were implicated in known pre/perinatal risk factors for psychosis. Genes coexpressed with radial glia were enriched with genes implicated in congenital abnormalities, birth weight, hypoxia, and starvation. Genes coexpressed with endothelial and mural genes were enriched with genes associated with maternal hypertension and preterm birth. Conclusions: Our findings support a neurodevelopmental model of vulnerability to mental illness whereby prenatal risk factors acting through cell-specific processes lead to deviations from typical brain development during pregnancy

    Subcortical volumes across the lifespan: data from 18,605 healthy individuals aged 3-90 years

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    Age has a major effect on brain volume. However, the normative studies available are constrained by small sample sizes, restricted age coverage and significant methodological variability. These limitations introduce inconsistencies and may obscure or distort the lifespan trajectories of brain morphometry. In response, we capitalized on the resources of the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium to examine age-related trajectories inferred from cross-sectional measures of the ventricles, the basal ganglia (caudate, putamen, pallidum, and nucleus accumbens), the thalamus, hippocampus and amygdala using magnetic resonance imaging data obtained from 18,605 individuals aged 3-90 years. All subcortical structure volumes were at their maximum value early in life. The volume of the basal ganglia showed a monotonic negative association with age thereafter; there was no significant association between age and the volumes of the thalamus, amygdala and the hippocampus (with some degree of decline in thalamus) until the sixth decade of life after which they also showed a steep negative association with age. The lateral ventricles showed continuous enlargement throughout the lifespan. Age was positively associated with inter-individual variability in the hippocampus and amygdala and the lateral ventricles. These results were robust to potential confounders and could be used to examine the functional significance of deviations from typical age-related morphometric patterns.Education and Child Studie

    Childhood Depression, Interpersonal Problem-Solving, and Self-Ratings of Performance

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    This study investigated the application of interpersonal and cognitive theories of adult depression to childhood depression. The Childhood Depression Inventory was administered to elementary school children, aged nine to eleven. Those scoring in the upper and lower third of the sample were designated as depressed (n = 20) and nondepressed (n = 20). Within two days, a measure of interpersonal problem‐solving ability, three questionnaire items assessing self‐ratings of interpersonal problem‐solving performance, and the vocabulary subtest of the WISC‐R were administered to the depressed and nondepressed subjects. Consistent with interpersonal and cognitive theories, depressed children showed poorer primary means‐ends problem‐solving performance and lower self‐ratings on items assessing social‐comparison and self‐satisfaction with interpersonal problem‐solving performance. Depressed children also scored significantly lower on the vocabulary subtest. These findings are discussed in terms of their similarity to the responses of depressed adult subjects and their implications for further research examining childhood depression
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