Installations from Privilege to Survival: Emergence and Evolution of Dalit Voice on Instagram Accounts

Growth of New Media has paved way for abundant possibility to articulate marginal voices. It is the emergence of social networking services that aids all the subaltern expressions to visualize their concerns on divergent virtual platforms. Visibility is the only path through which they can present their own underprivileged problems of discrimination and sense of identity. Ten years have passed since Instagram released its initial operations as a photo and video sharing space, and now the service witnesses a gradual shift of content creations. The proposed research paper traces the evolution of Instagram from a content-based perspective, arguing that the service has become a realm of survival as far as some communities are concerned drastically moving away from the privileged shutterbugs. It has the efficiency to advocate Dalit voice through multiple interactions. The paper attempts to analyse the Instagram accounts of Dalit Desk and The Blue Club foregrounding how the issues of caste atrocities in India are being mediated without the support of conventional media. The intervention of Instagram is perceived of two types in a structural approach; the first type being informative and persuasive for the common users where the second type seems to be academic and intellectual aiming to create potential exchanges on Dalit discourses. The former method makes use of the strategy of posting images directly which are related to segregation meanwhile the latter depends on a series of academic interactions in video format. Though the approaches are structurally different, they thematically intersect at a single point of representation. Considering the advancement of New Media as an alternative stream for the oppressed, the paper interprets distinctive installations in the form of real-life photos, short videos, posters, and long interactive videos as instances of rendering unheard inputs

Factors Associated with Revision Surgery after Internal Fixation of Hip Fractures

Background: Femoral neck fractures are associated with high rates of revision surgery after management with internal fixation. Using data from the Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) trial evaluating methods of internal fixation in patients with femoral neck fractures, we investigated associations between baseline and surgical factors and the need for revision surgery to promote healing, relieve pain, treat infection or improve function over 24 months postsurgery. Additionally, we investigated factors associated with (1) hardware removal and (2) implant exchange from cancellous screws (CS) or sliding hip screw (SHS) to total hip arthroplasty, hemiarthroplasty, or another internal fixation device. Methods: We identified 15 potential factors a priori that may be associated with revision surgery, 7 with hardware removal, and 14 with implant exchange. We used multivariable Cox proportional hazards analyses in our investigation. Results: Factors associated with increased risk of revision surgery included: female sex, [hazard ratio (HR) 1.79, 95% confidence interval (CI) 1.25-2.50; P = 0.001], higher body mass index (fo

Global Retinoblastoma Presentation and Analysis by National Income Level

Importance: Early diagnosis of retinoblastoma, the most common intraocular cancer, can save both a child's life and vision. However, anecdotal evidence suggests that many children across the world are diagnosed late. To our knowledge, the clinical presentation of retinoblastoma has never been assessed on a global scale. Objectives: To report the retinoblastoma stage at diagnosis in patients across the world during a single year, to investigate associations between clinical variables and national income level, and to investigate risk factors for advanced disease at diagnosis. Design, Setting, and Participants: A total of 278 retinoblastoma treatment centers were recruited from June 2017 through December 2018 to participate in a cross-sectional analysis of treatment-naive patients with retinoblastoma who were diagnosed in 2017. Main Outcomes and Measures: Age at presentation, proportion of familial history of retinoblastoma, and tumor stage and metastasis. Results: The cohort included 4351 new patients from 153 countries; the median age at diagnosis was 30.5 (interquartile range, 18.3-45.9) months, and 1976 patients (45.4) were female. Most patients (n = 3685 84.7%) were from low-and middle-income countries (LMICs). Globally, the most common indication for referral was leukocoria (n = 2638 62.8%), followed by strabismus (n = 429 10.2%) and proptosis (n = 309 7.4%). Patients from high-income countries (HICs) were diagnosed at a median age of 14.1 months, with 656 of 666 (98.5%) patients having intraocular retinoblastoma and 2 (0.3%) having metastasis. Patients from low-income countries were diagnosed at a median age of 30.5 months, with 256 of 521 (49.1%) having extraocular retinoblastoma and 94 of 498 (18.9%) having metastasis. Lower national income level was associated with older presentation age, higher proportion of locally advanced disease and distant metastasis, and smaller proportion of familial history of retinoblastoma. Advanced disease at diagnosis was more common in LMICs even after adjusting for age (odds ratio for low-income countries vs upper-middle-income countries and HICs, 17.92 95% CI, 12.94-24.80, and for lower-middle-income countries vs upper-middle-income countries and HICs, 5.74 95% CI, 4.30-7.68). Conclusions and Relevance: This study is estimated to have included more than half of all new retinoblastoma cases worldwide in 2017. Children from LMICs, where the main global retinoblastoma burden lies, presented at an older age with more advanced disease and demonstrated a smaller proportion of familial history of retinoblastoma, likely because many do not reach a childbearing age. Given that retinoblastoma is curable, these data are concerning and mandate intervention at national and international levels. Further studies are needed to investigate factors, other than age at presentation, that may be associated with advanced disease in LMICs. © 2020 American Medical Association. All rights reserved

A simple static headspace method for phase equilibrium measurement

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Local ecological knowledge (LEK) on fish behavior around anchored FADs : The case of tuna purse seine and ringnet fishers from Southern Philippines

The Fishing Industry in the Philippines plays an important role in the food and employment need of Filipino fishers. By using anchored Fish Aggregating Devices (FADs or payao), the Philippine tuna fisheries was transformed into a million-dollar industry. Minimal studies on exploitation rates and fish behavior around anchored FADs hampered further understanding of this fishery practice. Studies on fish behavior using Local Ecological Knowledge (LEK) are good complement where data is limited. A study using semi-structured interview (n = 46) and three focus group discussions (n = 39 participants) to record fishers' knowledge and observations on the behavior of different fish species around anchored FADs was conducted. This particularly focused on attraction, retention, and departure behavior of fishes in identified FAD sites. Based on the fishers' knowledge, tuna schools are attracted to anchored FADs at 10 km distance. In anchored FADs, tuna form schools segregated by species and size. There was no relationship between the attraction distance and the reported school size and the various waiting times for fish to aggregate below the FADs. There was no variation between the species present at day or night time although fishers have reported a distinction of species found near the surface (0-10 m) and those found at other depths (11-20 m). Juvenile yellowfin tuna (Thunnus albacares), skipjack (Katsuwonus pelamis), and frigate and bullet tunas (Auxis spp.) are found to stay at 25-50 m from the FAD at a depth of >20 m. Adult oceanic tunas reside in deeper waters (75 m). The fish visual census produced similar results with the semi-structured interviews and FGDs but did not observe oceanic tunas at depths of 15-20 m in the anchored FADs examined.</p

Ingestion of marine plastic debris by green turtle(Chelonia mydas) in davao gulf, Mindanao, Philippines

Marine plastic debris is a global problem that is threatening marine biodiversity. Different marine organisms have been exposed to the lethal and sub-lethal effects of this problem. Sub-lethal effects include reduced fitness due to reduced feeding, reduced reproductive output, limb amputation, and exposure to diseases and toxic materials, while lethal effects include drowning, gastro-intestinal blockage, and stomach rupture. Marine turtles are very vulnerable to these effects since these organisms actively ingest plastic mistaking it as prey. This adds stress to the declining population of marine turtles. On 17 April 2015, a dead adult female green turtle was recovered in Brgy. Lapu-lapu, Agdao, Davao City, Philippines. Necropsy showed that several plastic materials caused blockage in the pyloric end of the stomach which may have caused the turtle’s mortality.</p

<em>TP53</em> intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome.

Somatic mutations of TP53 are among the most common in cancer and germline mutations of TP53 (usually missense) can cause Li-Fraumeni syndrome (LFS). Recently, recurrent genomic rearrangements in intron 1 of TP53 have been described in osteosarcoma (OS), a highly malignant neoplasm of bone belonging to the spectrum of LFS tumors. Using whole-genome sequencing of OS, we found features of TP53 intron 1 rearrangements suggesting a unique mechanism correlated with transcription. Screening of 288 OS and 1,090 tumors of other types revealed evidence for TP53 rearrangements in 46 (16%) OS, while none were detected in other tumor types, indicating this rearrangement to be highly specific to OS. We revisited a four-generation LFS family where no TP53 mutation had been identified and found a 445 kb inversion spanning from the TP53 intron 1 towards the centromere. The inversion segregated with tumors in the LFS family. Cancers in this family had loss of heterozygosity, retaining the rearranged allele and resulting in TP53 expression loss. In conclusion, intron 1 rearrangements cause p53-driven malignancies by both germline and somatic mechanisms and provide an important mechanism of TP53 inactivation in LFS, which might in part explain the diagnostic gap of formerly classified &quot;TP53 wild-type&quot; LFS

Internationalization and Stock Market Liquidity

What is the impact of internationalization (firms raising capital and trading in international markets) on the liquidity of the remaining firms in domestic markets? To address this question, we assemble a panel database of nearly 2,900 firms from 45 emerging economies over the period 1989-2000, constructed from annual and daily data. First, we find evidence of migration. The domestic trading of firms that cross-list or issue depositary receipts in foreign public exchanges tends to decrease, while a significant proportion of their trading activity concentrates in international markets. Second, this migration is negatively related to the liquidity of the remaining firms in their home market through two separate channels. There are liquidity spillovers within markets: Aggregate domestic trading activity is positively associated with the liquidity of individual firms in the same market. Moreover, the proportion of trading abroad is negatively related to the liquidity of firms in the domestic market. Copyright 2006, Oxford University Press.