The mineral resources of the English Channel and Thames Estuary

This report accompanies the Marine mineral resource map the marine sand and gravel resources of the English Channel and Thames Estuary (Bide et al, 2012). It has been published as part of the research project Mineral Resource Assessment of the UK Continental Shelf commissioned by The Crown Estate. The map is one of a series that covers the UK Continental Shelf (UKCS). Knowledge of mineral resources is essential for effective and sustainable planning decisions. The marine mineral resource maps provide a comprehensive, relevant and accessible information base. This information will allow all stakeholders (planners, industry and members of the public) to visualise the distribution of offshore minerals to a common standard and at a common scale, an important requirement of an integrated marine planning system. The maps will also facilitate the conservation (safeguarding) of non-renewable mineral resources for future generations in accordance with the principles of sustainable development

A note on a result of Liptser-Shiryaev

Given two stochastic equations with different drift terms, under very weak assumptions Liptser and Shiryaev provide the equivalence of the laws of the solutions to these equations by means of Girsanov transform. Their assumptions involve both the drift terms. We are interested in the same result but with the main assumption involving only the difference of the drift terms. Applications of our result will be presented in the finite as well as in the infinite dimensional setting.Comment: 22 pages; revised and enlarged versio

The mineral resources of the East Inshore and East Offshore marine plan areas, southern North Sea

Minerals are naturally occurring raw materials essential for the development of a modern economy. However, mineral resources are finite and can only be worked where they occur. As their extraction is subject to many constraints, it is important that society uses minerals in the most efficient and sustainable manner. Identifying the distribution of known mineral resources on the UK Continental Shelf (UKCS) and presenting them in a consistent fashion at a national scale allows minerals to be considered in the marine spatial planning process and permits more effective and sustainable management strategies to be developed. The British Geological Survey (BGS) has undertaken a commission from The Crown Estate to prepare a series of mineral resource maps which cover the UKCS. Mineral resource information was compiled following a desk study of data held by the BGS and external sources. This report summarises the mineral resources depicted on the first of these maps - the East Inshore and East Offshore Marine Plan Areas in the southern North Sea. These are the first areas (Figure 1) for which the Marine Management Organisation is preparing marine plans (MMO, 2010). The map has been produced by the collation and interpretation of a wide range of information, much of which is spatially variable and not always available in a consistent and convenient form. The map depicts mineral resources of current or potential future economic interest in the area. It comprises a 1:500 000 scale map (which accompanies this report) depicting marine aggregate (sand and gravel) resources on the sea bed, and two 1:1 500 000 scale maps (as annexes in this report) depicting coal and evaporite resources at depth beneath the sea bed. These map scales are convenient for the overall display of the data. However, all the data are held digitally at larger scales using a Geographical Information System (GIS), which allows for revision, updating and customisation of the information, together with integration with other datasets

Rigorous results on superconducting ground states for attractive extended Hubbard models

We show that the exact ground state for a class of extended Hubbard models including bond-charge, exchange, and pair-hopping terms, is the Yang "eta-paired" state for any non-vanishing value of the pair-hopping amplitude, at least when the on-site Coulomb interaction is attractive enough and the remaining physical parameters satisfy a single constraint. The ground state is thus rigorously superconducting. Our result holds on a bipartite lattice in any dimension, at any band filling, and for arbitrary electron hopping.Comment: 12 page

Citrullination of α2-antiplasmin is unlikely to contribute to enhanced plasmin generation in COVID-19 pathophysiology

COVID-19 is caused by the SARS-CoV-2. Severe COVID-19 is characterized by immune cell activation, leading to inflammation and the formation of neutrophil extracellular traps (NETs). COVID-19 is also associated with an imbalance in coagulation and fibrinolytic activity. Exuberant fibrinogen production secondary to the inflammatory response, coupled with elevated thrombin generation, provokes fibrin deposition. However, despite paradoxically increased plasmin generation potential in plasma from patients with COVID-19, fibrinolytic pathways are unable to counter this process. Patients with severe COVID-19 have a high risk of developing venous thromboembolism, and patients with COVID-19 with venous thromboembolism have an increased risk of death

Flow profoundly influences fibrin network structure: Implications for fibrin formation and clot stability in haemostasis

Dear Sirs, Haemostasis requires fibrinogen conversion to fibrin and formation of a stable fibrin network. Fibrin network properties, including fibre thickness, branchpoint density, fibre density, mechanical stability, porosity, and resistance to lysis can differentiate plasma clots of healthy individuals from those with haemostatic or thrombotic disorders. Plasma from patients with a bleeding history produces thick, minimally-branched fibres in coarse, deformable networks that are highly susceptible to lysis, whereas plasma from patients with a personal or family history of thrombosis produces thin, highly-branched fibres in impermeable, rigid networks that are relatively resistant to fibrinolysi

Preserving the palaeoenvironmental record in Drylands: Bioturbation and its significance for luminescence-derived chronologies

Luminescence (OSL) dating has revolutionised the understanding of Late Pleistocene dryland activity. However, one of the key assumptions for this sort of palaeoenvironmental work is that sedimentary sequences have been preserved intact, enabling their use as proxy indicators of past changes. This relies on stabilisation or burial soon after deposition and a mechanism to prevent any subsequent re-mobilisation. As well as a dating technique OSL, especially at the single grain level, can be used to gain an insight into post-depositional processes that may distort or invalidate the palaeoenvironmental record of geological sediment sequences. This paper explores the possible impact of bioturbation (the movement of sediment by flora and fauna) on luminescence derived chronologies from Quaternary sedimentary deposits in Texas and Florida (USA) which have both independent radiocarbon chronologies and archaeological evidence. These sites clearly illustrate the ability of bioturbation to rejuvenate ancient weathered sandy bedrock and/or to alter depositional stratigraphies through the processes of exhumation and sub-surface mixing of sediment. The use of multiple OSL replicate measurements is advocated as a strategy for checking for bioturbated sediment. Where significant OSL heterogeneity is found, caution should be taken with the derived OSL ages and further measurements at the single grain level are recommended. Observations from the linear dunes of the Kalahari show them to have no bedding structure and to have OSL heterogeneity similar to that shown from the bioturbated Texan and Florida sites. The Kalahari linear dunes could have therefore undergone hitherto undetected post-depositional sediment disturbance which would have implications for the established OSL chronology for the region

Single-top Wt-channel production matched with parton showers using the POWHEG method

We present results for the next-to-leading order calculation of single-top Wt-channel production interfaced to Shower Monte Carlo programs, implemented according to the POWHEG method. A comparison with MC@NLO is carried out. Results obtained using the PYTHIA shower are also shown and the effect of typical cuts is briefly discussed.Comment: 23 pages, 9 figure

Health behavior correlates among colon cancer survivors: NC STRIDES baseline results

Objective: To examine health behaviors (fruit/vegetable intake and physical activity) and their association with social cognitive theory (SCT) constructs among colorectal cancer (CRC) survivors (n=304) and comparable non-CRC-affected participants (n=521). Methods: Baseline data were analyzed bivariately and modeled with linear regression. Participants were 48% female, 36% African American (mean age = 67). Results: Behaviors were comparable between groups, but survivors perceived more social support for behaviors (P<.05). Lack of employment was associated with greater frequency of healthy behaviors (P<.05) as were more modifiable factors including higher self-efficacy and lower barriers. Conclusions: SCT constructs were associated with behavior and may be targets for future interventions, but other variables may be important as well

Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms

Clonal proliferation in myeloproliferative neoplasms (MPN) is driven by somatic mutations in JAK2, CALR or MPL, but the contribution of inherited factors is poorly characterized. Using a three-stage genome-wide association study of 3,437 MPN cases and 10,083 controls, we identify two SNPs with genome-wide significance in JAK2V617F-negative MPN: rs12339666 (JAK2; meta-analysis P=1.27 × 10−10) and rs2201862 (MECOM; meta-analysis P=1.96 × 10−9). Two additional SNPs, rs2736100 (TERT) and rs9376092 (HBS1L/MYB), achieve genome-wide significance when including JAK2V617F-positive cases. rs9376092 has a stronger effect in JAK2V617F-negative cases with CALR and/or MPL mutations (Breslow–Day P=4.5 × 10−7), whereas in JAK2V617F-positive cases rs9376092 associates with essential thrombocythemia (ET) rather than polycythemia vera (allelic χ2 P=7.3 × 10−7). Reduced MYB expression, previously linked to development of an ET-like disease in model systems, associates with rs9376092 in normal myeloid cells. These findings demonstrate that multiple germline variants predispose to MPN and link constitutional differences in MYB expression to disease phenotype