889 research outputs found

    De EMU:Hoe en waarom?

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    Rousing reviews and instigative images: The impact of online reviews and visual design characteristics on app downloads

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    Mobile apps are very popular. However, this is not true for every app, with some apps receiving millions of downloads, while other apps are mostly ignored. We investigate the popularity of apps in terms of downloads by focusing on two salient cues: (a) online recommendations (e.g., presence and valence of online reviews) and (b) visual characteristics of app icons (e.g., use of visual metaphors and anthropomorphism). Study 1 was a field study in which we content-analyzed 500 apps from the “transportation” subcategory of the Google Play Store. We found that the presence and valence of online reviews, as well as the presence of visual metaphors in app icons were positively related to the number of app downloads. Study 2 was an experiment in which we presented participants with different app icons containing different types of visual metaphors. We again found that app icons with visual metaphors led to more positive attitudes towards the apps and behavioral intentions. Combined, our studies show that both online consumers (through online reviews) and app designers (through visual design) impact an app’s popularity. </jats:p

    Hergebruik ijzerrijk drinkwaterslib biedt kansen voor natuurontwikkeling

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    Hoge fosfaatbeschikbaarheid in voormalige landbouwpercelen belemmert natuurbeheerders bij het omvormen van deze terreinen naar natuurgebieden. Het opbrengen van ijzerrijk drinkwaterslib verlaagt de fosforbeschikbaarheid en lijkt daarom een goed alternatief voor gronden waar afgraven van de fosfaatrijke toplaag geen optie is

    Real-time propagators at finite temperature and chemical potential

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    We derive a form of spectral representations for all bosonic and fermionic propagators in the real-time formulation of field theory at finite temperature and chemical potential. Besides being simple and symmetrical between the bosonic and the fermionic types, these representations depend explicitly on analytic functions only. This last property allows a simple evaluation of loop integrals in the energy variables over propagators in this form, even in presence of chemical potentials, which is not possible over their conventional form

    Coherent effects in double-barrier Josephson junctions

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    The general solution for ballistic electronic transport through double-barrier Josephson junctions is derived. We show the existence of a regime of phase-coherent transport in which the supercurrent is proportional to the single barrier transparency and the way in which this coherence is destroyed for increasing interlayer thickness. The quasiparticle dc current at arbitrary voltage is determined.Comment: 4 pages, 2 figures, submitted to Phys. Rev.

    Modulating local airway immune responses to treat allergic asthma: lessons from experimental models and human studies

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    With asthma affecting over 300 million individuals world-wide and estimated to affect 400 million by 2025, developing effective, long-lasting therapeutics is essential. Allergic asthma, where Th2-type immunity plays a central role, represents 90% of child and 50% of adult asthma cases. Research based largely on animal models of allergic disease have led to the generation of a novel class of drugs, so-called biologicals, that target essential components of Th2-type inflammation. Although highly efficient in subclasses of patients, these biologicals and other existing medication only target the symptomatic stage of asthma and when therapy is ceased, a flare-up of the disease is often observed. Therefore, it is suggested to target earlier stages in the inflammatory cascade underlying allergic airway inflammation and to focus on changing and redirecting the initiation of type 2 inflammatory responses against allergens and certain viral agents. This focus on upstream aspects of innate immunity that drive development of Th2-type immunity is expected to have longer-lasting and disease-modifying effects, and may potentially lead to a cure for asthma. This review highlights the current understanding of the contribution of local innate immune elements in the development and maintenance of inflammatory airway responses and discusses available leads for successful targeting of those pathways for future therapeutics

    Modulating local airway immune responses to treat allergic asthma: lessons from experimental models and human studies

    Get PDF
    With asthma affecting over 300 million individuals world-wide and estimated to affect 400 million by 2025, developing effective, long-lasting therapeutics is essential. Allergic asthma, where Th2-type immunity plays a central role, represents 90% of child and 50% of adult asthma cases. Research based largely on animal models of allergic disease have led to the generation of a novel class of drugs, so-called biologicals, that target essential components of Th2-type inflammation. Although highly efficient in subclasses of patients, these biologicals and other existing medication only target the symptomatic stage of asthma and when therapy is ceased, a flare-up of the disease is often observed. Therefore, it is suggested to target earlier stages in the inflammatory cascade underlying allergic airway inflammation and to focus on changing and redirecting the initiation of type 2 inflammatory responses against allergens and certain viral agents. This focus on upstream aspects of innate immunity that drive development of Th2-type immunity is expected to have longer-lasting and disease-modifying effects, and may potentially lead to a cure for asthma. This review highlights the current understanding of the contribution of local innate immune elements in the development and maintenance of inflammatory airway responses and discusses available leads for successful targeting of those pathways for future therapeutics.Pathogenesis and treatment of chronic pulmonary disease

    Nucleon propagation through nuclear matter in chiral effective field theory

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    We treat the propagation of nucleon in nuclear matter by evaluating the ensemble average of the two-point function of nucleon currents in the framework of the chiral effective field theory. We first derive the effective parameters of nucleon to one loop. The resulting formula for the effective mass was known previously and gives an absurd value at normal nuclear density. We then modify it following Weinberg's method for the two-nucleon system in the effective theory. Our results for the effective mass and the width of nucleon are compared with those in the literature.Comment: 11 pages including 4 figures. To appear in Eur. J. Phys.
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