119 research outputs found
Kinematics of gas and stars in circumnuclear star-forming regions of early type spirals
(Abbr.) We present high resolution (R~20000) spectra in the blue and the far
red of cicumnuclear star-forming regions (CNSFRs) in three early type spirals
(NGC3351, NGC2903 and NGC3310) which have allowed the study of the kinematics
of stars and ionized gas in these structures and, for the first time, the
derivation of their dynamical masses for the first two. In some cases these
regions, about 100 to 150 pc in size, are seen to be composed of several
individual star clusters with sizes between 1.5 and 4.9 pc estimated from
Hubble Space Telescope (HST) images. The stellar dispersions have been obtained
from the Calcium triplet (CaT) lines at 8494,8542,8662 \AA,
while the gas velocity dispersions have been measured by Gaussian fits to the
H and [OIII] 5007 \AA lines on the high dispersion
spectra. Values of the stellar velocity dispersions are between 30 and 68 km/s.
We apply the virial theorem to estimate dynamical masses of the clusters,
assuming that systems are gravitationally bounded and spherically symmetric,
and using previously measured sizes. The measured values of the stellar
velocity dispersions yield dynamical masses of the order of 10 to 10
solar masses for the whole CNSFRs. Stellar and gas velocity dispersions are
found to differ by about 20 to 30 km/s with the H emission lines being
narrower than both the stellar lines and the [OIII] 5007 \AA
lines. The twice ionized oxygen, on the other hand, shows velocity dispersions
comparable to those shown by stars, in some cases, even larger. We have found
indications of the presence of two different kinematical components in the
ionized gas of the regions...Comment: 4 pages, proceeding of the meeting "Young massive star clusters -
Initial conditions and environments", Granada, Spain, 200
Unmodified cellulose filter paper, a sustainable and affordable sorbent for the isolation of biogenic amines from beer samples
While current trends in Green Analytical Chemistry aim at reducing or simplifying sample treatment, food usually comprises complex matrices where direct analysis is not possible in most cases. In this context, sample treatment plays a pivotal role. Biogenic amines are naturally formed in many foodstuffs due to the action of microorganisms, while their presence has been associated with adverse health effects. In this work, the extraction of seven biogenic amines (cadaverine, histamine, phenylethylamine, putrescine, spermidine, spermine, and tyramine) from beer samples has been simplified using laboratory filter paper as sorbent without any further modification. The analysis of the eluates by direct infusion mass spectrometry reduces the time of analysis, increasing the sample throughput. This simple but effective method enabled the determination of the analytes with limits of detection as low as 0.06 mg L−1 and relative standard deviations better than 11.9%. The suitability of the method has been assessed by analyzing eight different types of beers by the standard addition method
Defibrotide inhibits donor leucocyte-endothelial interactions and protects against acute graft-versus-host disease
Altres ajuts: This study has been funded by Josep Carreras Leukaemia Foundation (Grant 11R/2016 and 03R/2019).Allogeneic hematopoietic stem cell transplantation (allo-HCT) is an effective therapy for the treatment of high-risk haematological malignant disorders and other life-threatening haematological and genetic diseases. Acute graft-versus-host disease (aGvHD) remains the most frequent cause of non-relapse mortality following allo-HCT and limits its extensive clinical application. Current pharmacologic agents used for prophylaxis and treatment of aGvHD are not uniformly successful and have serious secondary side effects. Therefore, more effective and safe prophylaxis and therapy for aGvHD are an unmet clinical need. Defibrotide is a multi-target drug successfully employed for prophylaxis and treatment of veno-occlusive disease/sinusoidal obstruction syndrome. Recent preliminary clinical data have suggested some efficacy of defibrotide in the prevention of aGvHD after allo-HCT. Using a fully MHC-mismatched murine model of allo-HCT, we report here that defibrotide, either in prophylaxis or treatment, is effective in preventing T cell and neutrophil infiltration and aGvHD-associated tissue injury, thus reducing aGvHD incidence and severity, with significantly improved survival after allo-HCT. Moreover, we performed in vitro mechanistic studies using human cells revealing that defibrotide inhibits leucocyte-endothelial interactions by down-regulating expression of key endothelial adhesion molecules involved in leucocyte trafficking. Together, these findings provide evidence that defibrotide may represent an effective and safe clinical alternative for both prophylaxis and treatment of aGvHD after allo-HCT, paving the way for new therapeutic approaches
Phase transitions for suspension flows
This paper is devoted to study thermodynamic formalism for suspension flows
defined over countable alphabets. We are mostly interested in the regularity
properties of the pressure function. We establish conditions for the pressure
function to be real analytic or to exhibit a phase transition. We also
construct an example of a potential for which the pressure has countably many
phase transitions.Comment: Example 5.2 expanded. Typos corrected. Section 6.1 superced the note
"Thermodynamic formalism for the positive geodesic flow on the modular
surface" arXiv:1009.462
Normal-superconducting transition induced by high current densities in YBa2Cu3O7-d melt-textured samples and thin films: Similarities and differences
Current-voltage characteristics of top seeded melt-textured YBa2Cu3O7-d are
presented. The samples were cut out of centimetric monoliths. Films
characteristics were also measured on microbridges patterned on thin films
grown by dc sputtering. For both types of samples, a quasi-discontinuity or
quenching was observed for a current density J* several times the critical
current density Jc. Though films and bulks much differ in their magnitude of
both Jc and J*, a proposal is made as to a common intrinsic origin of the
quenching phenomenon. The unique temperature dependence observed for the ratio
J*/Jc, as well as the explanation of the pre-quenching regime in terms of a
single dissipation model lend support to our proposal.Comment: 10 pages, 10 figures, submitted to Physical Review
Robust exponential decay of correlations for singular-flows
We construct open sets of Ck (k bigger or equal to 2) vector fields with
singularities that have robust exponential decay of correlations with respect
to the unique physical measure. In particular we prove that the geometric
Lorenz attractor has exponential decay of correlations with respect to the
unique physical measure.Comment: Final version accepted for publication with added corrections (not in
official published version) after O. Butterley pointed out to the authors
that the last estimate in the argument in Subsection 4.2.3 of the previous
version is not enough to guarantee the uniform non-integrability condition
claimed. We have modified the argument and present it here in the same
Subsection. 3 figures, 34 page
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